Anticoagulants

MAHATHIR ALPHA · 55問 · 2年前

通報

問題一覧

Commonly Used Anticoagulants

EDTA, Double oxalate, Sodium citrate, Sodium fluoride, Heparin, ACD, CPD, CPDA

Complete name of EDTA

Ethyle Diamine Tetra Acetic Acid

Complete name of ACD

Acid Citrate Dextrose

Complete name of CPD

Citrate Phosphate Dextrose

Complete name of CPDA

Citrate Phosphate Dextrose Adenine

Anticoagulant with the ff. charactetistics: -Chelates Ca -Uses: •Cell count •Blood smear •Platelet count

EDTA

Used for routine hematological work and has an chelating effect on calcium molecule in blood

EDTA

Three types of EDTA salts used in salt or liquid form

Sodium, Potassium, Lithium

True/False: Dipotassium salt is more soluble than Disodium salt, therefore they are more preffered.

True

Coding of vial for EDTA

Lavender cap

Recommended concentration for EDTA

1.5 to 2 ml

True/False: Trisodium EDTA is NOT recommended brcause of high pH

True

Anticoagulant with the ff. charactetistics: -Binds Ca in soluble complex -Uses: •Coagulation studies

Sodium citrate

Acts by chelatkng calcium in blood and is used as 3.2% and 3.8% solution.

Trisodium citrate

Coding of Vial for Sodium citrate

Blue cap

Coding of Vial for Heparin

Green cap

Coding of Vial for ACD

Yellow cap

Coding of vial for Sodium fluoride

Gray cap

Coding of vial for NO ADDITIVE

Red cap

It binds Ca to form insoluble Ca oxalate and distorts cell morphology.

Oxalate

Anticoagulant with the ff. charactetistics: -Inactivates thrombin -Uses: •Osmotic fragility test

Heparin

Anticoagulant with the ff. charactetistics: -Preservative -Prevents glycolysis

Fluoride

It is used for determination of Blood Sugar.

Sodium fluoride

Type YES after reading...

YES

Salt of Heparin which is commonly used for chemistry, gas analysis and emergency tests.

Lithium salt

It is the best Anticoagulant for osmotic fragility tests and suitable for phenotyping.

Heparin

Heparin is produced by what?

Basophils, Mast cells

Type YES after reading ...

YES

Type YES after reading... USES OF HEPARIN

YES

Preserve RBC for Blood bankong and HLA typing

ACD

Inhibit Thrombin activation

Heparin

For Glucose Determination

Sodium flouride

Anticoagulant for WBC preservation

ACD

Anticoagulants for Blood Storage

ACD, CPD, CPDA, Heparin

Type YES after reading...

YES

Causes chelation of calcium

Citrate

Prevents fall in pH

Sodium diphosphate

It is added in modified CPD as it improves viability of RBC because of enchanced ATP production

Adenine

Adjust osmotic pressure

Sodium chloride

Maintains high level of ATP in RBC

Adenine

Prevents disintegration of RBC

Mannitol

2 pathways for energy production

Embedem Mayeroff pathway, Pentose phosphate pathway

Prevents carmalization of glucose in citrate dextrose solution during autoclaving.

Citric acid

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