記憶度
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Appearance in Supravital stain: Dark blur-purple, fine or coarse punctate granules distributed throughout the cytoplasm
Basophilic stippling
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Associated diseases/conditions of Cabot ring
Megaloblastic anemia, Myelodysplastic syndrome
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What is the composition of Hemoglobin H?
Precipitated B-globin chains of hemoglobin
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Appearance in Supravital stain: Dark blue granules and filaments in cytoplasm (seen in reticulocyte)
Diffuse basophilia
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What is the appearance of Hemoglobin H in Wright stain?
Not visible
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Associated diseases/conditions of Howell-Jolly body
Hyposplenism, Postsplenectomy, Megaloblastic anemia, Thalassemia, Myelodysplastic syndromes
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What is the composition of Heinz body?
Denatured hemoglobin
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What is the appearance of Cabot ring in Wright stain?
Blue rings or figure-eights
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What is the composition of Diffuse basophilia?
RNA
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Commonly associated disease states with Teardrop cell (Dacryocyte).
Primary myelofibrosis, Myelophthisic anemia, Thalassemia, Megaloblastic anemia
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Appearance in Supravital stain: Fine, evenly dispersed, dark blue granules, imparts "golf ball" appearance to RBCs.
Hemoglobin H
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Associated diseases/conditions of Basophilic stippling
Lead poisoning, Thalassemias, Hemoglobinopathies, Megaloblastic anemia, Myelodysplastic syndromes
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Associated diseases/conditions of Diffuse basophilia
Hemolytic anemia, Folate deficiency
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Appearance in Supravital stain: Rings or figure-eights
Cabot ring
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Commonly associated disease states with Burr cell (Echinocyte).
Uremia, Pyruvate kinase deficiency
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What is the composition of Howell-Jolly body?
DNA(nuclear fragment)
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Associated diseases/conditions of Heinz bodies
Glucose-6-phosphate dehydrogenase deficiency, Unstable hemoglobin, Oxidant drugs/chemicals
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What is the appearance of Diffuse basophilia in Wright stain?
Bluish tinge throughout cytoplasm, also called polychromasia (seen in polychromatic erythrocytes).
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RBC with blunt or pointed, short projections that are usually evenly spaced over the surface of cell; present in all fields of blood film but in variable numbers per field.
Burr cell (echinocyte)
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What is the appearance of Heinz body in Wright stain?
Not visible
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Associated diseases/conditions of Pappenheimer bodies
Sideroblastic anemia, Hemoglobinopathies, Thalassemia, Megablastic anemia, Myelodysplastic syndrome, Hyposplenism, Postsplenectomy
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What is the composition of Cabot ring?
Mitotic spindle remnant
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Round, dark-purple granule attached to inner RBC membrane.
Heinz bodies
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What is the composition of Pappenheimer bodies?
Iron
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Appearance in Supravital stain: Irregular clusters of small, light to dark granules often near periphery of cell.
Pappenheimer bodies
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RBC with a single pointed extension resembling a teardrop or pear.
Teardrop cell (dacryocyte)
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What is the appearance of Pappenheimer bodies in Wright stain?
Irregular clusters of small, light to dark granules, often near periphery of cell
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What is the appearance of Howell-Jolly body in Wright stain?
Dark blue-purple dense, round granule, usually one per cell; occasionaly multiple
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What is the composition of Basophilic stippling?
Precipitated RNA
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Appearance in Supravital stain: Dark blue-purple, round granule, usually one per cell; occasionally multiple.
Howell-Jolly body
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Associated diseases/conditions of Hemoglobin H
Hemoglobin H disease
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What is the appearance of Basophilic stippling in Wright stain?
Dark blue-purple, fine or course punctate granules distributed throughout cytoplasm.