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The Control of Microbial Growth Part 1
  • MAHATHIR ALPHA

  • 問題数 62 • 10/21/2023

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  • 1

    It refers to the destruction and removal of all forms of microbial life, including endospores. And is usually done by steam under pressure or a sterilizing gas such as ethylene oxide.

    Sterilization

  • 2

    Give one example of a sterilizing gas used for sterilization

    Ethylene oxide

  • 3

    It refers to the use of sufficient heat treatment to kill endospores of Clostridium botulinum in canned foods.

    Commercial sterilization

  • 4

    What endospore of an bacteria can survive but will not be able to germinate and grow under normal storage condition in commercial sterilization?

    Thermophilic bacteria

  • 5

    it leads to the destruction of vegetative pathogens. And may make use of physical or chemical methods.

    Disinfection

  • 6

    It leads to the destruction of vegetative state pathogens on living tissues. and the treatment is always by chemical antimicrobials.

    Antiseptics

  • 7

    True/False: Antisepsis treatment is always by chemical antimicrobials.

    True

  • 8

    What is destroyed during disinfection

    Vegetative pathogens

  • 9

    Commercial sterilization treament are used to kill endospores of what microorganisms in canned foods?

    Clostridium botulinum

  • 10

    What is used for mechanical removal in degerming?

    Alcohol-soaked swab

  • 11

    It refers to the removal of microbes from a limited area such as the skin around the injection site. Mostly a mechanical removal by an alcohol-soaked swab.

    Degerming

  • 12

    It is a treatment which is intended to lower microbial counts on eating and drinking utensils to safe public health levels. It can be done with a high temperature washing or by dipping into a chemical disinfectant.

    Sanitation

  • 13

    True/False: Sanitation cannot be done with a high temperature washing or by dipping into a chemical disinfectant.

    False

  • 14

    True/False: Bacterial population DO NOT die at a constant rate when heated or treated with antimicrobial agents.

    False

  • 15

    For each minute the bacterial population is treated or heated with antimicrobial agents, how many of the population is killed?

    90 percent

  • 16

    What are the factors affecting the effectiveness of antimicrobial treatments?

    The number of microbes, Environmental influences, Time of exposure, Microbial characteristics

  • 17

    It kills microorganism primarily by coagulation of proteins (denaturation), which caused by breakage of the hydrogen bonds that hold the protein.

    Moist heat

  • 18

    It refers to the coagulation of proteins.

    Protein denaturation

  • 19

    It kills vegetative bacterial and fungal pathogens and almost all viruses within 10 minutes, less effective on endospores.

    Boiling or flowing steam

  • 20

    How long does it take for a boiling or flowing stream to kill vegetative bacterial and fungal pathogens and almost all viruses?

    10 minutes

  • 21

    This method is used in Dishes, Basins and Pitchers.

    Boiling or flowing steam

  • 22

    What is the mechanism of Action of Boiling or flowing steam?

    Protein denaturation

  • 23

    What are the physical methods that are used to control microbial growth?

    Heat, Cold, High pressure, Desiccation, Osmotic pressure, Radiation

  • 24

    It is a very effective method of sterilization, at about 15 psi (121°C), all vegetative cells and their endospores are killed in about 15 mins.

    Autoclaving

  • 25

    How long does it takes for vegetative cells and their endospores to be killed after Autoclaving?

    15 minutes

  • 26

    What are Autoclaving used in?

    Microbiological media, Solutions, Linens, Utensils, Dressings, Other items that can withstand temperature and pressure

  • 27

    What is the mechanism of action of Autoclaving?

    Protein denaturation

  • 28

    It refers to the use of mild heating which is sufficient to kill the microorganisms that can cause spoilage problem without really damaging the taste of the product.

    Pasteurization

  • 29

    What is the heat treatment for milk?

    72° for 15 seconds

  • 30

    Pasteurization is used in what?

    Milk, Cream, Certain alcoholic beverages( beer and wine)

  • 31

    What is the mechanism of action for Pasteurization?

    Protein denaturation

  • 32

    It kills by oxidation effect

    Dry heat

  • 33

    It is a very effective method of sterilization is used in Inoculating loops.

    Direct flaming

  • 34

    It is a very effective method of sterilization that is used in paper cups, contaminated dressings, animal carcasses, bags and wipes.

    Incineration

  • 35

    It is a very effective method of sterilization but requires temperature at 170°C for about 2 hours.

    Hot-air sterilization

  • 36

    Where is hot-air sterilization used in?

    Empty glassware, Instruments, Needles, Glass syringes

  • 37

    What is the mechanism of action of Direct flaming?

    Burning contaminants into ashes

  • 38

    What is the mechanism of action of Incineration?

    Burning to ashes

  • 39

    What is the mechanism of action of Hot-air sterilization?

    Oxidation

  • 40

    Most filters in filtration method in use consist what?

    Cellulose , Nitrocellulose

  • 41

    What is the mechanism of action of filtration?

    Separation of bacteria from suspending liquid

  • 42

    The passage of a liquid or gas through a screen like materials with pores small enough to retain microbes.

    Filtration

  • 43

    It is used to sterilize heat sensitive materials such as enzymes, vaccines and antibiotic solutions. And removes microbes by passage of a liquid or gas.

    Filtration

  • 44

    Where is filtration method used in?

    Sterilizing liquids(enzymes, vaccines) that are destroyed by heat

  • 45

    It has a bacteriostatic effect and is often used in food, drug and culture preservation.

    Refrigeration

  • 46

    What is the mechanism of action of Refrigeration?

    Decreased chemical reactions and possible changes in protein

  • 47

    It is an effective method for preserving microbial cultures, in which cultures are quick-frozen between -50°C and 95°C. And is also used in food, drug and culture preservation.

    Deep-freezing

  • 48

    What is the mechanism of action of Deep-freezing?

    Decreased chemical reactions and possible changes in protein

  • 49

    What is the mechanism of action of Lyophilization?

    Decreased chemical reactions and possible changes in protein

  • 50

    In this method, water is removed by high vacuum at low temperature.

    Lyophilization

  • 51

    It is the most effective method for long term preservation of microbial culture.

    Lyophilization

  • 52

    It is used for the preservation of colors and nutrient values. and is often used in fruit juices.

    High pressure

  • 53

    What is the mechanism of action of High pressure?

    Alteration of molecular structure of proteins and carbohydrates.

  • 54

    It involves removing of water from microbes; primarily bacteriostatic. and is used in food preservation.

    Desiccation

  • 55

    What is the mechanism of action of desiccation?

    Disruption of metabolism

  • 56

    It results in loss of water from microbial cells and is also used in Food preservation.

    Osmotic pressure

  • 57

    What is the mechanism of action of Osmotic pressure?

    Plasmolysis

  • 58

    It can kill microorganism in two ways( Ionizing and Non-ionizing).

    Radiation

  • 59

    Involves the use gamma rays or high energy electron and is not widespread in routine sterilization.

    Ionizing radiation

  • 60

    It is used for sterilizing pharmaceuticals and medical and dental supplies.

    Ionizing radiation

  • 61

    In this type of radiation, the radiation is not very penetrating. And is used for control of closed environment with UV lamp.

    Non-ionizing radiation

  • 62

    Mechanism of Action of Ionizing Radiation

    Destruction of DNA