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Pathogenesis Part 1
  • MAHATHIR ALPHA

  • 問題数 78 • 10/15/2023

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  • 1

    Development of an infection and disease

    Pathogenesis

  • 2

    It involves the growth and multiplication of microorganisms that causes damage to the host.

    Infection

  • 3

    It is the bodily invasion of pathogenic microorganisms that reproduce, multiply, and then cause diseases through local cellular injury, toxin secretion or antigen-antibody reaction in the host.

    Infection

  • 4

    What are the types of Infection according to the Cause?

    Autogenous infection, Iatrogenic infection, Opportunistic infection, Nosocomial infection

  • 5

    This type of infection is caused by a microorganism from the microbiota of the host.

    Autogenous infection

  • 6

    This type of infection is an infection that occurs as the result of some medical treatment or procedure

    Iatrogenic infection

  • 7

    This type of infection is an infection that affects immunocompromised host but not the individual with a normal immune system

    Opportunistic infection

  • 8

    This type of infection is also known as the hospital- acquired infection and is a acquired at a healthcare facility

    Nosocomial infection

  • 9

    It still considered as the cornerstone of modern infection control programs

    Handwashing

  • 10

    What are the 4 common types of Nosocomial Infections?

    Urinary tract infection, Lung infection, Surgical site infection, Blood stream infection

  • 11

    What are the Predisposing factors to Nosocomial Infection?

    Wide variety of microbes in the hospital environment, Weakened or immuno compromised patients

  • 12

    Chain of transmission of Nosocomial Infection

    From health worker to patients, From patients to patients, Use of fomites, Airborne transmission, Vector-borne transmission

  • 13

    What are the types of Infection according to Host Distribution?

    Local infection, Focal infection, Systemic infection

  • 14

    In this type of infection, the signs and symptoms are confined in one area.

    Local infection

  • 15

    This type of infection starts as an local infection before spreading to the other parts of the body.

    Focal infection

  • 16

    In this type of infection, the microbes spread throughout the body through the blood or lymph.

    Systemic infection

  • 17

    What are the types of systematic infections?

    Bacteremia, Septicemia, Pyremia

  • 18

    The presence of bacteria in blood

    Bacteremia

  • 19

    True/False: Organisms invade the bloodstream with Active Multiplication

    False

  • 20

    True/False: The highest concentration of bacteria in the blood occurs before the fever spikes.

    True

  • 21

    Active multiplication of the invading bacteria in the blood

    Septicemia

  • 22

    It is a condition wherein pus-producing organisms reapetedly invade the bloodstream and become localized at different parts of the body.

    Pyremia

  • 23

    What are the extent of Infection?

    Primary infection, Secondary infection, Latent infection, Mixed infection, Acute infection, Chronic infection

  • 24

    It is the initial infection that causes the illness

    Primary infection

  • 25

    Give an example of primary infection

    Common cold

  • 26

    It is an infection caused by opportunistic pathogens after the primary infection has weakened the host's immune system

    Secondary infection

  • 27

    Give examples of secondary infections

    Pneumonia, Bronchitis

  • 28

    It is an infection which is clinically silent inside the body and causes no noticable illness in the host. Then severe and acute infraction manifest.

    Latent infection

  • 29

    Give an example of Latent infection

    Asymptomatic type polio infection

  • 30

    It is an infection caused by two or more organisms

    Mixed infection

  • 31

    Give an example of Mixed infection

    Wound infection

  • 32

    Type of infection that develops and progresses slowly

    Acute infection

  • 33

    Example of an Acute infection

    Whooping cough

  • 34

    An infection which develops slowly with milder but long lasting symptoms

    Chronic infection

  • 35

    Give an example of chronic infection

    Tuberculosis

  • 36

    Give the routes of infections through Direct Transmission

    Congenital contact, Sexual contact, Infectious respiratory secretions, Hand to hand transmission

  • 37

    Microbes that are transmitted through Congenital Contact

    Streptococcus agalactiae , Neisseria gonorrhoeae, Treponema pallidum

  • 38

    Microbes that are transmitted through sexual contact

    Neisseria gonorrhoeae, Treponema pallidum

  • 39

    Microbes that are transmitted through Infectious respiratory secretions or droplets.

    Streptococcus pyogenes, Neisseria meningitidis

  • 40

    Microbes transmitted through hand to hand transmission

    Rhinovirus

  • 41

    Give the routes of infections through Indirect Transmission

    Fomites, Water, Arthropod vectors

  • 42

    A specific illness or disorder that is characterized by a recognizable signs and symptoms which are attributable to heredity, infection, and environment.

    Disease

  • 43

    It results when the infection produces notable changes in the human physiology, specifically those that cause damage to the body's organ system

    Disease

  • 44

    List down the Classification of Infectious Diseases

    Communicable disease, Non-communicable disease

  • 45

    This type of disease spreads from one host to another, either directly or indirectly.

    Communicable disease

  • 46

    Give examples of Communicable diseases.

    Tuberculosis, Herpes, Flu, Chicken pox

  • 47

    This type of disease does not spread from one host to another. And caused by external microbes or by opportunistic pathogens living in the body.

    Non-communicable disease

  • 48

    Give examples of Non-communicable disease

    Tetanus, Botulism

  • 49

    List down the Classification of Disease According to Occurence

    Sporadic disease, Endemic disease, Epidemic disease, Pandemic disease

  • 50

    This type of disease occurs ocassionally

    Sporadic disease

  • 51

    This type of disease is constantly present in a particular location or population.

    Endemic disease

  • 52

    This type of disease is a disease that affects a large number of people in a population within a short period of time

    Epidemic disease

  • 53

    This is a disease that affects populations across large regions around the world.

    Pandemic disease

  • 54

    These are objective changes that can be measured. Examples are fever, redness, swelling, and paralysis

    Signs

  • 55

    These are subjective indications of the disease in a person. Examples are pain and malaise.

    Symptoms

  • 56

    It is a group of signs and symptoms that are associated with a disease. Example is AIDS.

    Syndrome

  • 57

    The Phases of Infectious Disease

    Incubation period, Prodromal period, Clinical period or illness period, Decline period, Convalescence or the period of recovery

  • 58

    The time between the exposure to a pathogenic organism and the onset of symptoms.

    Incubation period

  • 59

    In this phase of infectious disease, the signs and symptoms would appear

    Prodromal period

  • 60

    The peak of characteristic signs and symptoms of an infection or a disease.

    Clinical or illness period

  • 61

    The period in which the signs and symptoms begin to subside as the host's condition improves.

    Decline period

  • 62

    The period in which the surviving host is recuperating towards full recovery.

    Convalescence or the period of recovery

  • 63

    List down the Predisposing Factors of Diseases

    Gender, Genetic factors, Climate and weather, Nutrition, Fatigue/stress, Environment, Lifestyle, Age, Occupation

  • 64

    Give the 2 General Classes of Pathogenic Microorganisms

    True pathogen, Opportunistic pathogens

  • 65

    Give examples of Opportunistic pathogens

    Neisseria meningitidis, Escherichia coli

  • 66

    These organisms are able to invade the tissues of healthy individuals through some inherent ability causing various diseases. normally found outside the host.

    True pathogen

  • 67

    These organisms normally do not cause diseases in their natural habitat in healthy person. They cause diseases if the host is immunocompromised or if they enter a different part of the body.

    Opportunistic pathogens

  • 68

    Types of Host-microbe Relationship

    Symbiosis, Mutualism, Commensalism, Parasitism

  • 69

    It is the association of two organisms living in close proximity.

    Symbiosis

  • 70

    It is a symbiotic relationship in which both organisms benefit from each other.

    Mutualism

  • 71

    It is a relationship in which one organism benefits while there is no beneficial or harmful effect to the other.

    Commensalism

  • 72

    It is a relationship in which one organism (parasite) benefits at the expense of its host.

    Parasitism

  • 73

    It is a complex interaction between the host, indwelling device, and bacteria and is a key component in bacterial pathogenesis.

    Biofilm production

  • 74

    It pertains to the ability of a pathogenic agent to produce a disease in a susceptible individual.

    Pathogenicity

  • 75

    Give some examples of Focal Infection.

    Tooth infection, Tonsillitis, Appendicitis, Wound infection

  • 76

    Tooth infection, tonsillitis, appendicitis and wound infections are caused by what?

    Clostridium tetani

  • 77

    Give some examples of Local Infection.

    Infected wounds, Boils, Abscesses

  • 78

    "memory cell" of the immune system

    B- lymphocyte