Common Clinically Significant Hemoglobinopathies

MAHATHIR ALPHA · 55問 · 2年前

通報

問題一覧

What is the Hemoglobin solubility test result for Sickle cell Anemia?

Positive

What is the Hemoglobin solubility test result for Hb C disease?

Negative

What is the Hemoglobin solubility test result for Hb SC-Harlem?

Positive

What is the Hemoglobin solubility test result for Hb E disease?

Negative

What is the Hemoglobin solubility test result for Hb O-Arab?

Negative

What is the Hemoglobin solubility test result for Hb D disease?

Negative

What is the Hemoglobin solubility test result for Hb G disease?

Negative

What is the Hemoglobin solubility test result for Hb SC disease?

Positive

What is the Hemoglobin solubility test result for Hb S-B-thalassemia?

Positive

What is the Hemoglobin solubility test result for Hb SG?

Positive

What is the Hemoglobin solubility test result for Hb SD disease?

Positive

What is the Hemoglobin solubility test result for Hb SO-Arab

Positive

What is/are the abnormal hemoglobin in Sickle cell anemia?

Hb S

What is/are the abnormal hemoglobin in Hb C disease?

Hb C

What is/are the abnormal hemoglobin in Hb SC-Harlem?

Hb C-Harlem, Hb S

What is/are the abnormal hemoglobin in Hb E disease?

Hb E

What is/are the abnormal hemoglobin in Hb O-Arab disease?

Hb O-Arab

What is/are the abnormal hemoglobin in Hb D disease?

Hb D-Punjab

What is/are the abnormal hemoglobin in Hb G disease?

Hb G, Hb G-Philadelphia

What is/are the abnormal hemoglobin in Hb SC disease?

Hb S, Hb C

What is/are the abnormal hemoglobin in Hb S-B-Thalessemia?

Hb S, B thalassemia mutation

What is/are the abnormal hemoglobin in Hb SD disease?

Hb S, Hb D

What is/are the abnormal hemoglobin in Hb SG disease?

Hb S, Hb G

What is/are the abnormal hemoglobin in Hb SO-Arab disease?

Hb S, Hb O-Arab

List down the Homozygous Hemoglobin Disorders?

Sickle cell anemia, Hb C disease, Hb E disease, Hb O-Arab disease

List down the Rare Homozygous Hemoglobin Disorders?

Hb D disease, Hb G disease

List down the Hemoglobin disorders that is/are not Homozygous?

Hb SC-Harlem disease, Hb SC disease, Hb S-B-Thalassemia, Hb SD disease, Hb SG disease, Hb SO-Arab

Which groups are primarily affected by Sickle cell Anemia?

African, African American, Middle Eastern, Indian, Mediterranian

Which groups are primarily affected by Hb SC disease?

African, African American, Middle Eastern, Indian, Mediterranian

Which groups are primarily affected by Hb S-B-thalassemia?

African, African American, Middle Eastern, Indian, Mediterranian

Which groups are primarily affected by Hb SD disease?

African, African American, Middle Eastern, Indian, Mediterranian

Which groups are primarily affected by HB SG disease?

African, African American, Middle Eastern, Indian, Mediterranian

Which groups are primarily affected by Hb SO-Arab?

African, African American, Middle Eastern, Indian, Mediterranian

Which groups are primarily affected by Hb C?

African, African American

Which groups are primarily affected by Hb SC-Harlem?

Rare, so uncertain; African, African American

Which groups are primarily affected by Hb E?

African, African American, Southeast Asian

Which groups are primarily affected by Hb O-Arab?

Kenyan, African American, Israeli, Egyptian, Bulgarian

Which groups are primarily affected by Hb D?

Middle Eastern, Indian

Which groups are primarily affected by Hb G?

African American, Ghanaian

What RBC morphology of Sickle cell anemia?

Sickle cell, Target cell, Polychromasia, Nucleated RBCs, Howell-Jolly body, Basophilic stippling

What RBC morphology of Hb C disease?

Hb C crystal, Target cells, Nucleated RBCs, Occasionally some Microcytes

What RBC morphology of Hb SC-Harlem?

Target cells

What RBC morphology of Hb E disease ?

Target cells, Microcyte

What RBC morphology of Hb O-Arab

Target cells

What RBC morphology of Hb D disease?

Target cells

What RBC morphology of Hb G disease?

Target cells

What is the RBC morphology of Hb SC disease?

Sickle cells, Hb SC crystals, Target cells

What RBC morphology of S-B-thalassemia?

Sickle cell, Target cell, Microcytes

What RBC morphology of Hb SD disease?

Sickle cells, Target cells

What RBC morphology of Hb SG disease?

Target cells

What RBC morphology of Hb SO-Arab

Sickle cells, Target cells

What is the symptoms/organ defects of Sickle cell anemia?

Vasoocclusion, Bacterial infections, Hemolytic anemia, Aplastic episodes

What is the symptoms/organ defects of Hb C disease?

Mild splenomegaly, Mild hemolysis

What is the symptoms/organ defects of Hb SC-Harlem disease?

Similar symptoms to Hb SS

What is the symptoms/organ defects of Hb E?

Mild splenomegaly, Mild anemia, No symptoms

What is the symptoms/organ defects of Hb O-Arab?

Mild splenomegaly

What is the symptoms/organ defects of Hb D disease?

Mild hemolytic anemia, Mild splenomegaly

What is the symptoms/organ defects of Hb G disease?

Mild splenomegaly, Mild hemolytic anemia

What is the symptoms/organ defects of Hb SC

Similar to Hb SS but milder

What is the symptoms/organ defects of Hb S-B-thalassemia?

Hemolytic anemia, Splenomegaly

What is the symptoms/organ defects of Hb SD disease?

Similar to Hb SS but milder

What is the symptoms/organ defects of Hb SG disease?

No symptom

What is the symptoms/organ defects of Hb SO-Arab?

Similae to Hb SS

Translation(Pre-finals)

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Transcription

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