問題一覧
1
What makes up 10-20 percent of the lymphoid population?
B lymphocytes
2
What is found in the Marginating pool?
50% PMNs that adhere to the vessel walls or are sequenstered in the capillaries
3
Youngest stage
Metamyelocyte/juvenile
4
Short-lived lymphocyte with humoral-mediated immunity
B lymphocyte
5
What is the cytoplasm staining of Promyelocyte?
Basophilic
6
What are the Secondary or Specific Granules found in Basophil?
Histamine, Heparin, Peroxidase, Eosinophilic Chemotactic Factor A
7
Youngest cell to appear in peripheral blood
Band
8
What are found in the Mitotic pool?
Myeloblast, Promyelocyte, Myelocyte
9
What is the cytoplasm staining of Band?
Beige/Salmond
10
What is the Normal range of WBC of Infants upto 1 year of age?
6000-16000/uL of blood
11
Its major function is to provide defense against helmenthic parasites and it has a role in allergic reactions by lessening hypersensitivity reactions through the release of an amine oxidase, which neutralizes histamine.
Eosinophil
12
In this stage of the lymphocyte, the size of the cell is 10-12 um, chromatin not as dense as small lymphocyte.
Medium lymphocyte
13
How long is the maturation sequence of Granulocytes?
About 14 days
14
It is a stage of lymphocyte wherein its cytoplasm is nongranular, moderate and darkblue in color
Prolymphocyte
15
What are the POOLS of Neutrophils in the body?
Bone marrow-production and maturation, Blood
16
Lymphocyte with tumor host defense
Null lymphocytes
17
N, E, B
Mature granulocyte
18
What are the Secondary or Specific Granules found in the Storage pool?
Metamyelocyte, Bands, Segmented PMN's
19
First appearance of primary granules
Promyelocyte
20
It is formed from the disintegration of eosinophils and is made up of lysophospholipase found in the cytoplasm of eosinophils.
Charcot-Leyden Crystal
21
What are found in the maturing pool?
Metamyelocyte
22
It refer to the detection of changes in numbers of circulating WBCs(percentage of each type). It indicates infection, poisoning, leukemia, chemotheraphy, parasites or allergy reactions.
Differential WBC counts
23
What is the Normal range of WBC of Adults?
4000-11000/uL of blood
24
In Neutrophil, it competes with bacteria for Fe (possibly inhibiting growth) and may promote PMN adherence to endothelial cells.
Lactoferrin-Fe binding glycoprotein
25
In this stage of the granulocyte, the size of the cell is 12-18 um, has a oval/round nucleus, a coarser and condensed chromatin and no Nucleoli.
Myelocyte
26
What are the Secondary or Specific Granules found in Neutrophil?
Aminopeptidase, Collagenase, Muramidase, Lactoferrin, Lysozyme, Basic proteins, Plasminogen activator, Alkaline phosphatase
27
1st recognizable in granulocytic series
Myeloblast
28
What is the Ratio of primary to secondary granules of Mature neutrophil?
2-3:1
29
What is the other term for Neutrophil?
Polymorphonuclear (PMN)
30
It is a stage of lymphocyte wherein its cytoplasm is more abundant, pale moderate blue in color.
Medium Lymphocyte
31
What are the stages of Plasma cells?
Plasmablast, Proplasmacyte, Plasmacyte/plasma cell
32
In this stage of the granulocyte, the size of the cell is 10-16 um, has a Unsegmented/bi lobed nucleus, a condensed nucleus and no Nucleoli.
Basophil
33
What are found in the Circulating pool?
50% of PMNs circulating freely
34
What are the Smaller Secondary or Specific Granules found in Eosinophil?
Arylsulfatase, Peroxidase, Acid phosphatase
35
What are the granules found on Eosinophil?
Reddish-orange with affinity for eosin(acidic)
36
What makes up 60-80 percent of the lymphoid population?
T lymphocyte
37
In this stage of the granulocyte, the size of the cell is 15-21 um, has a oval/round nucleus, a slightly coarse chromatin and 2-3 Nucleoli.
Promyelocyte
38
What are the Larger Secondary or Specific granules/Major basic Proteins found in Eosinophil?
Acid hydrolase, Peroxidase, Phospholipase, Cathepsin, Eosinophilic Cationic CHON, Eosinophil-derived neurotoxin
39
It responds to allergic or hypersensitivity reactions a such as allergic asthma and delayed-onset allergy reaction
Basophil
40
First appearance of secondary granules
Myelocyte
41
It is a stage of lymphocyte wherein its cytoplasm is thin rim around nucleus and Robin's egg blue.
Mature small lymphocyte
42
True/False: Concentration of Eosinophil is normally high at night or in the afternoon.
True
43
In this stage of the lymphocyte, the size of the cell is 12-16 um, it has a round/oval nucleus and nucleoli is not visible, abundant clear and very pale blue cytoplasm
Large lymphocyte
44
In this stage of the granulocyte, The size of the cell is 15-20 um, has a round/slightly oval nucleus, a fine chromatin and 2-5 Nucleoli.
Myeloblast
45
Try to Memorize!
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46
In this stage of the lymphocyte, the size of the cell is 10-18 um, it has a coarse chromatin, round/oval nucleus, a coarse 1-2 Nucleoli.
Lymphoblast
47
What is the life span of Neutrophil/Polymorphonuclear (PMN)?
9-10 days
48
Long lived lymphocyte (4-10 years) with cellular-mediated immunity
T lymphocyte
49
Charcot-Leyden crystal are seen in what conditions?
Allergic asthma (nasal mucos), Pulmonary eosinophilic infiltrates (pleural fluid), Parasitic infection (stool)
50
What is the cytoplasm staining of Metamyelocyte?
Beige/Salmon
51
What is the cytoplasm staining of myelocyte?
Basophilic acidophilic
52
It is the orderly production of mature granulocytes (N,E,B)
Granulocyte production
53
What are the stages of lymphocyte?
Lymphoblast, Prolymphocyte, Mature small lymphocyte, Medium lymphocyte, Large lymphocyte
54
What are the POOLS of Neutrophils in the Blood?
Circulating pool, Marginating pool
55
What makes up 10 percent percent of the lymphoid population?
Null lymphocyte
56
What are the granules found in Basophil?
Water soluble blue black specific granules with affinity to methylene blue
57
What is Charcot-Leyden crystal made of?
Lysophospholipase
58
In this stage of the lymphocyte, the size of the cell is the same as lymphoblast or smaller, it has a more clumped chromatin, round/oval nucleus, a coarse 1-2 Nucleoli.
Prolymphocyte
59
What is the cytoplasm staining of Neutrophil, eosinophil and basophil?
Beige/Salmond
60
What is the Normal range of WBC at birth or infants?
10,000-25,000/uL of blood
61
It responds to parasitic and helminthic infection and allergy.
Eosinophil
62
It is a stage of lymphocyte wherein its cytoplasm appears smooth, has no granules and moderate dark blue in color
Lymphoblast
63
In this stage of the lymphocyte, the size of the cell is 8-10 um, it has a dense chromatin, round/oval nucleus, a not visible Nucleoli.
Mature small lymphocyte
64
What does Eosinophil releases that neutralize histamine?
Amine oxidase
65
What are the POOLS of Neutrophil in the Bone marrow production and maturation?
Mitotic pool, Maturing pool, Storage pool
66
What are the granules found in Neutrophil?
Pink-rose violet granules
67
It is the Major basic CHON -arginine- rich protein that plays a major role in killing parasites
Eosinophil