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Antimicrobial (Antibiotics)
  • MAHATHIR ALPHA

  • 問題数 66 • 11/9/2023

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    問題一覧

  • 1

    What is the antibiotics that is produced by the microorganism Streptomyces nodosus?

    Amphotericin B

  • 2

    What is the antibiotics that is produced by the microorganism Streptomyces noursei?

    Nystatin

  • 3

    Amphotericin B is produced by what microorganism?

    Streptomyces nodosus

  • 4

    What is the antibiotics that is produced by the microorganism Streptomyces venezuelae?

    Chloramphenicol

  • 5

    Nystatin is produced by what microorganism?

    Streptomyces noursei

  • 6

    Chloramphenicol is produced by what microorganism?

    Streptomyces venezuelae

  • 7

    What is the antibiotics that is produced by the microorganism Bacillus subtilis?

    Bacitracin

  • 8

    What is the antibiotics that is produced by the microorganism Bacillus polymyxa?

    Polymyxin

  • 9

    Bacitracin is produced by what microorganism?

    Bacillus subtilis

  • 10

    Polymyxin is produced by what microorganism?

    Bacillus polymyxa

  • 11

    What is the antibiotics that is produced by the microorganism Cephalosporium?

    Cephalosporins

  • 12

    Cephalosphorin is produced by what microorganism?

    Cephalosphorium

  • 13

    What is the antibiotics that is produced by the microorganism Micromonospora purpurea?

    Gentamicin

  • 14

    Gentamicin is produced by what microorganism?

    Micromonospora purpurea

  • 15

    What is the antibiotics that is produced by the microorganism Penicillium notatum?

    Penicillin

  • 16

    Penicillin is produced by what microorganism?

    Penicillium notatum

  • 17

    What is the antibiotics that is produced by the microorganism Streptomyces erythraeus?

    Erythromycin

  • 18

    What is the antibiotics that is produced by the microorganism Streptomyces Fradiae?

    Neomycin

  • 19

    Erythromycin is produced by what microorganism?

    Streptomyces erythraeus

  • 20

    Neomycin is produced by what microorganism?

    Streptomyces fradiae

  • 21

    What are the antiobiotics under Narrow-spectrum?

    Bacitracin, Clindamycin, Erythromycin, Gentamicin, Penicillin, Vancomycin

  • 22

    What are the antiobiotics under Broad spectrum?

    Ampicillin, Cephalosporins, Chloramphenicol, Ciprofloxacin, Rifampicin, Trimethoprim, Tetracycline

  • 23

    What are the classification of Antibacterial Drugs?

    Natural drugs, Semi-synthetic drugs, Synthetic drugs

  • 24

    Give examples of Natural drugs

    Erythromycin, Amphotericin B, Vancomycin, Tetracycline, Penicillin

  • 25

    Give examples of Semi-synthetic drugs

    Ampicillin, Carbenicillin, Methicillin

  • 26

    Give examples of Synthetic drugs

    Sulfonamides, Trimethoprim, Ciprofloxacin, Isoniazid

  • 27

    What are the classification of Antimicrobial agents?

    Bacteriostatic agents, Bactericidal agents

  • 28

    Give examples of Bacteriostatic agents

    Chloramphenicol, Erythromycin, Clindamycin

  • 29

    Give examples of Bactericidal agents

    Aminoglycosides, B-lactams, Glycopeptides

  • 30

    The capacity to inhibit other microorganisms

    Bacteriostatic

  • 31

    What are the kinds of Antimicrobial agents?

    Cell wall inhibitors, Protein synthesis inhibitors, Nucleic acid inhibitors, Cell membrane inhibitors, Essential metabolite inhibitors

  • 32

    The capacity to kill other microorganisms

    Bactericidal

  • 33

    Give examples of Nucleic acid inhibitors

    Rifampicin, Quinolones, Metronidazole

  • 34

    This kind of Antimicrobial agents are the most selective antibiotics with a high therapeutic index. Inhibits the transpeptidase enzymes in which cell growth stops and the death of the cells occurs.

    Cell wall inhibitor

  • 35

    These are chemical substances produced by microorganisms with the capacity to inhibit or kill other microorganisms.

    Antimicrobials

  • 36

    They are effective against a limited number of pathogens. Example: Bacitracin, clindamycin, erythromycin, gentamicin, penicillin and Vancomycin

    Narrow-spectrum

  • 37

    Give an example of Cell membrane inhibitors

    Polymyxin B and E

  • 38

    Give examples of Cell wall inhibitors

    Bacitracin, B-lactams, Isoniazid, Vancomycin, Carbenicillin, Penicillin

  • 39

    Give examples of Essential metabolite inhibitors

    Sulfamethoxazole (SMZ), Dapsone, Trimethoprim

  • 40

    They destroy different kinds of organisms. Example: Ampicillin, cephalosporins, chloramphenicol, ciprofloxacin, rifampicin, trimethoprim and tetracycline.

    Broad spectrum

  • 41

    Give examples of Protein synthesis inhibitors.

    Tetracycline, Aminoglycosides, Erythromycin, Chloramphenicol, Clindamycin, Linezoid

  • 42

    It is the kind of Antimicrobial agent that binds with a 30S subunit that result in the misreading of mRNA and 50S subunit that results in the inhibition of peptidyl transferase and peptide chain elongation.

    Protein synthesis inhibitors

  • 43

    This type of Antimicrobial drugs are produced by bacteria or fungi. Ex.: Erythromycin, amphotericin B, vancomycin, tetracycline, penicillin

    Natural drugs

  • 44

    It inhabits RNA polymerase.

    Rifampicin

  • 45

    It inhibits the synthesis of peptidoglycan precursors.

    Bacitracin

  • 46

    It interferes with DNA gyarase and topoisomerase IV and highly effective for enteric bacteria.

    Quinolones

  • 47

    This type of Antimicrobial drugs are modified drugs with added chemical groups. Ex.: Ampicillin, carbenicillin and methicillin.

    Semi-synthetic drugs

  • 48

    This type of Antibacterial drugs are chemically --produced drugs. Ex.: Sulfonamides, trimethoprim, ciprofloxacin, isoniazid.

    Synthetic drugs

  • 49

    It disrupts DNA and is effectice against anaerobic bacteria.

    Metronidazole

  • 50

    It inhibits transpeptidation.

    B-lactams

  • 51

    Gram- negatige bacteria (P. aeuruginosa) also used as a topical antibiotic.

    Polymyxin B and E

  • 52

    This type of bacteriostatic agent usually kill or destroy organisms and are used for the treatment of life-threatening infections. Ex. Aminoglycosides, B-lactams, Glycopeptide

    Bactericidal agents

  • 53

    It acts on growing cells and can either be a bactericidal or bactetiostatic agent.

    Isoniazid

  • 54

    It inhibits the translocation and elongation of peptidoglycan.

    Vancomycin

  • 55

    It inhibits folic acid and metabolism and has a higher therapeutic index.

    Sulfamethoxazole (SMZ)

  • 56

    This type of bacteriostatic agent inhibit the bacterial growth but generally they do not kill the microorganisms. Ex. Chloramphenicol, erythromycin, clindamycin

    Bacteriostatic agents

  • 57

    It blocks the initial step in protein synthesis.

    Linezolid

  • 58

    It interferes with folic acid sythesis.

    Dapsone

  • 59

    What are the Characteristics of Antimicrobial agents?

    1. Must be in an active form., 2. Must able to achieve concentration at the site of infection that is higher than the pathogen's MIC to be effective., 3. Must have "selective toxicity".

  • 60

    They are genetic elements that are capable of integrating genes(cassettes) by an integrin encoded site-specific recombinase.

    Integrons

  • 61

    It blocks the tetrahydrofale synthesis.

    Trimethoprim

  • 62

    It is the lowest concentration of a drug that can still inhibit bacterial growth.

    Minimal-inhibitory concentration (MIC)

  • 63

    It is the lowest concentration of a drug that can kill bacteria.

    Minimal lethal concentration

  • 64

    They are enzymes (transpeptidase or transglycolase) that mediate peptidoglycan cross-linking with reduced affinity for B-lactam antibiotics.

    Penicillin-binding proteins

  • 65

    It is the ratio of the toxic dose to the therapeutic dose and as such, the higher the therapeutic index, the more effective the chemotherapeutic agent.

    Therapeutic index

  • 66

    These are DNA elements that encode transposition and excision functions and which are also able to carry antibiotic resistance genes among plasmids and chromosomes.

    Transposons