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問題一覧
1
What is the antibiotics that is produced by the microorganism Streptomyces nodosus?
Amphotericin B
2
What is the antibiotics that is produced by the microorganism Streptomyces noursei?
Nystatin
3
Amphotericin B is produced by what microorganism?
Streptomyces nodosus
4
What is the antibiotics that is produced by the microorganism Streptomyces venezuelae?
Chloramphenicol
5
Nystatin is produced by what microorganism?
Streptomyces noursei
6
Chloramphenicol is produced by what microorganism?
Streptomyces venezuelae
7
What is the antibiotics that is produced by the microorganism Bacillus subtilis?
Bacitracin
8
What is the antibiotics that is produced by the microorganism Bacillus polymyxa?
Polymyxin
9
Bacitracin is produced by what microorganism?
Bacillus subtilis
10
Polymyxin is produced by what microorganism?
Bacillus polymyxa
11
What is the antibiotics that is produced by the microorganism Cephalosporium?
Cephalosporins
12
Cephalosphorin is produced by what microorganism?
Cephalosphorium
13
What is the antibiotics that is produced by the microorganism Micromonospora purpurea?
Gentamicin
14
Gentamicin is produced by what microorganism?
Micromonospora purpurea
15
What is the antibiotics that is produced by the microorganism Penicillium notatum?
Penicillin
16
Penicillin is produced by what microorganism?
Penicillium notatum
17
What is the antibiotics that is produced by the microorganism Streptomyces erythraeus?
Erythromycin
18
What is the antibiotics that is produced by the microorganism Streptomyces Fradiae?
Neomycin
19
Erythromycin is produced by what microorganism?
Streptomyces erythraeus
20
Neomycin is produced by what microorganism?
Streptomyces fradiae
21
What are the antiobiotics under Narrow-spectrum?
Bacitracin, Clindamycin, Erythromycin, Gentamicin, Penicillin, Vancomycin
22
What are the antiobiotics under Broad spectrum?
Ampicillin, Cephalosporins, Chloramphenicol, Ciprofloxacin, Rifampicin, Trimethoprim, Tetracycline
23
What are the classification of Antibacterial Drugs?
Natural drugs, Semi-synthetic drugs, Synthetic drugs
24
Give examples of Natural drugs
Erythromycin, Amphotericin B, Vancomycin, Tetracycline, Penicillin
25
Give examples of Semi-synthetic drugs
Ampicillin, Carbenicillin, Methicillin
26
Give examples of Synthetic drugs
Sulfonamides, Trimethoprim, Ciprofloxacin, Isoniazid
27
What are the classification of Antimicrobial agents?
Bacteriostatic agents, Bactericidal agents
28
Give examples of Bacteriostatic agents
Chloramphenicol, Erythromycin, Clindamycin
29
Give examples of Bactericidal agents
Aminoglycosides, B-lactams, Glycopeptides
30
The capacity to inhibit other microorganisms
Bacteriostatic
31
What are the kinds of Antimicrobial agents?
Cell wall inhibitors, Protein synthesis inhibitors, Nucleic acid inhibitors, Cell membrane inhibitors, Essential metabolite inhibitors
32
The capacity to kill other microorganisms
Bactericidal
33
Give examples of Nucleic acid inhibitors
Rifampicin, Quinolones, Metronidazole
34
This kind of Antimicrobial agents are the most selective antibiotics with a high therapeutic index. Inhibits the transpeptidase enzymes in which cell growth stops and the death of the cells occurs.
Cell wall inhibitor
35
These are chemical substances produced by microorganisms with the capacity to inhibit or kill other microorganisms.
Antimicrobials
36
They are effective against a limited number of pathogens. Example: Bacitracin, clindamycin, erythromycin, gentamicin, penicillin and Vancomycin
Narrow-spectrum
37
Give an example of Cell membrane inhibitors
Polymyxin B and E
38
Give examples of Cell wall inhibitors
Bacitracin, B-lactams, Isoniazid, Vancomycin, Carbenicillin, Penicillin
39
Give examples of Essential metabolite inhibitors
Sulfamethoxazole (SMZ), Dapsone, Trimethoprim
40
They destroy different kinds of organisms. Example: Ampicillin, cephalosporins, chloramphenicol, ciprofloxacin, rifampicin, trimethoprim and tetracycline.
Broad spectrum
41
Give examples of Protein synthesis inhibitors.
Tetracycline, Aminoglycosides, Erythromycin, Chloramphenicol, Clindamycin, Linezoid
42
It is the kind of Antimicrobial agent that binds with a 30S subunit that result in the misreading of mRNA and 50S subunit that results in the inhibition of peptidyl transferase and peptide chain elongation.
Protein synthesis inhibitors
43
This type of Antimicrobial drugs are produced by bacteria or fungi. Ex.: Erythromycin, amphotericin B, vancomycin, tetracycline, penicillin
Natural drugs
44
It inhabits RNA polymerase.
Rifampicin
45
It inhibits the synthesis of peptidoglycan precursors.
Bacitracin
46
It interferes with DNA gyarase and topoisomerase IV and highly effective for enteric bacteria.
Quinolones
47
This type of Antimicrobial drugs are modified drugs with added chemical groups. Ex.: Ampicillin, carbenicillin and methicillin.
Semi-synthetic drugs
48
This type of Antibacterial drugs are chemically --produced drugs. Ex.: Sulfonamides, trimethoprim, ciprofloxacin, isoniazid.
Synthetic drugs
49
It disrupts DNA and is effectice against anaerobic bacteria.
Metronidazole
50
It inhibits transpeptidation.
B-lactams
51
Gram- negatige bacteria (P. aeuruginosa) also used as a topical antibiotic.
Polymyxin B and E
52
This type of bacteriostatic agent usually kill or destroy organisms and are used for the treatment of life-threatening infections. Ex. Aminoglycosides, B-lactams, Glycopeptide
Bactericidal agents
53
It acts on growing cells and can either be a bactericidal or bactetiostatic agent.
Isoniazid
54
It inhibits the translocation and elongation of peptidoglycan.
Vancomycin
55
It inhibits folic acid and metabolism and has a higher therapeutic index.
Sulfamethoxazole (SMZ)
56
This type of bacteriostatic agent inhibit the bacterial growth but generally they do not kill the microorganisms. Ex. Chloramphenicol, erythromycin, clindamycin
Bacteriostatic agents
57
It blocks the initial step in protein synthesis.
Linezolid
58
It interferes with folic acid sythesis.
Dapsone
59
What are the Characteristics of Antimicrobial agents?
1. Must be in an active form., 2. Must able to achieve concentration at the site of infection that is higher than the pathogen's MIC to be effective., 3. Must have "selective toxicity".
60
They are genetic elements that are capable of integrating genes(cassettes) by an integrin encoded site-specific recombinase.
Integrons
61
It blocks the tetrahydrofale synthesis.
Trimethoprim
62
It is the lowest concentration of a drug that can still inhibit bacterial growth.
Minimal-inhibitory concentration (MIC)
63
It is the lowest concentration of a drug that can kill bacteria.
Minimal lethal concentration
64
They are enzymes (transpeptidase or transglycolase) that mediate peptidoglycan cross-linking with reduced affinity for B-lactam antibiotics.
Penicillin-binding proteins
65
It is the ratio of the toxic dose to the therapeutic dose and as such, the higher the therapeutic index, the more effective the chemotherapeutic agent.
Therapeutic index
66
These are DNA elements that encode transposition and excision functions and which are also able to carry antibiotic resistance genes among plasmids and chromosomes.
Transposons