HEMATOLOGY PROGRESS EXAM PART 2

35問 • 1年前

問題一覧

The majority of the iron in an adult is found as a constituent of: * 1/1 Hemoglobin Hemosiderin Myoglobin Transferrin

Hemoglobin

An increased amount of cytoplasmic basophilia in a blood cell indicates: * 1/1 Increased cytoplasmic maturation Decreased cytoplasmic maturation Reduction in size of the cell Decreased nuclear maturation

Decreased cytoplasmic maturation

Which of the following cytokines is most responsible for eosinophil differentiation and release from the bone marrow? * 0/1 IL-1 IL-2 IL-4 IL-5

IL-5

After the removal of red blood cells from the circulation hemoglobin is broken down into: * 1/1 Iron, porphyrin, and amino acids Iron, heme, and globin Heme, protoporphyrin, and amino acids Heme, hemosiderin, and globin

Iron, heme, and globin

Anemia secondary to uremia and chronic renal disease characteristically is: * 0/1 Microcytic, hypochromic Hemolytic Normocytic, normochromic Macrocytic

Normocytic, normochromic

Which abnormal RBC morphology is associated with pyruvate kinase deficiency? * 0/1 Acanthocytes Dacryocytes Echinocytes Drepanocytes

Echinocytes

Which of the following hemoglobinopathies is associated with rod shaped crystals? * 1/1 Hb S Hb C Hb SC Hb D

Hb C

The Philadelphia chromosome is formed by a translocation between: * 1/1 Chromosome 22 and chromosome 9 Chromosome 21 and chromosome 9 Chromosome 21 and chromosome 6 Chromosome 22 and chromosome 6

Chromosome 22 and chromosome 9

Biochemical abnormalities characteristic of polycythemia vera include: * 0/1 Increased serum B12 binding capacity Hypouricemia Hypohistaminemia Increased erythropoietin

Increased serum B12 binding capacity

The disease state that presents with QUANTITATIVE platelet disorder is: * 0/1 von Willebrand disease Hemophilia A Glanzmann thrombasthenia May-Hegglin anomaly

May-Hegglin anomaly

Automated methods of measuring hemoglobin cannot detect this form: * 0/1 Methemoglobin Carboxyhemoglobin Deoxyhemoglobin Sulfhemoglobin

Sulfhemoglobin

In the hemoglobin solubility (dithionate) test, which type of hemoglobin causes turbidity (positive reaction)? * 1/1 Hb D Hb E Hb S Hb A

Hb S

The hemoglobin variant that is seen frequently in the South East Asian population, demonstrates a microcytic blood smear, and migrates with HbC at pH 8.6 is: * 0/1 Hb Barts Hb F Hb E Hb H

Hb E

Which of the following markers are usually negative in hairy cell leukemia? * 0/1 CD 5 CD 11c CD 25 CD 103

CD 5

Which condition is associated with the BCR/ABL gene rearrangement and responds well to treatment with tyrosine kinase inhibitors? * 1/1 Chronic myeloid leukemia Essential thrombocytosis Chronic idiopathic myelofibrosis Polycythemia vera

Chronic myeloid leukemia

Which of the following conditions is most often associated with the V617F mutation of JAK2? * 0/1 Chronic myelogenous leukemia Acute monocytic leukemia MDS with multilineage dysplasia Polycythemia vera

Polycythemia vera

Vasoconstriction is caused by several regulatory molecules, which include: * 1/1 Fibrinogen and vWF ADP and EPI Thromboxane A2 and serotonin Collagen and actomyosin

Thromboxane A2 and serotonin

The most potent plasminogen activator in the contact phase of coagulation is: * 0/1 Kallikrein Streptokinase HMWK Fibrinogen

Kallikrein

The activation of plasminogen to plasmin resulting in the degradation of fibrin occurs by: * 1/1 PAl-1 Alpha-2 antiplasmin tPA Alpha-2 macroglobulin

tPA

An inhibitor of plasmin activity is: * 0/1 tPA PAl-1 Alpha-2 antiplasmin Plasminogen

Alpha-2 antiplasmin

The 2 factors that differentiate liver disease from vitamin K deficiency are: * 1/1 II and VII IX and VII VIII and IX V and VII

V and VII

In patients who present with bleeding disorders caused by platelets, the most common type of bleeding is: * 1/1 Mucosal bleeding Hemarthrosis Delayed bleeding Deep hematomas

Mucosal bleeding

The most common cause of bleeding in patients is: * 0/1 Qualitative platelet defect Qualitative abnormality of fibrinogen Quantitative abnormality of fibrinogen Quantitative abnormality of platelets

Quantitative abnormality of platelets

Which subtype of van Willebrand disease is the most common? * 0/1 Type 1 Type 2A Type 2B Type 3

Type 1

Platelet aggregation will occur with the end production of: * 1/1 Cyclooxygenase Arachidonic acid Prostacyclin Thromboxane A2

Thromboxane A2

A pregnant women has routine coagulation testing performed. PT and aPTT are normal. Her fibrinogen level is elevated at 450 (reference range 150-350) due to acute phase reactants during pregnancy. The other factor that may be elevated due to this is: * 0/1 FVII FVIII FXI FXIII

FVIII

Which of the following are characteristic of a factor XII deficiency? * 0/1 Negative bleeding history Negative screening test Decreased risk of thrombosis Decreased platelet count

Negative bleeding history

One of the coagulation test results that correlates with mortality in patients with the SARS-CoV-2 virus was: * 1/1 PT APTT D-dimer Thrombin time

D-dimer

If small blood clot exists in an anticoagulated blood specimen, which blood cell parameter will be affected the most? * 0/1 Leukocyte count Erythrocyte count Platelet count Microhematocrit

Platelet count

Sometimes used in conjunction with DC: * 0/1 Electronic impedance Optical scatter Radiofrequency None of these

Radiofrequency

RL flag except: * 0/1 Platelet clumps RBC fragments Giant platelets Cold agglutinins

Cold agglutinins

The primary pathophysiologic mechanism of anemia associated with chronic kidney disease is: * 1/1 Inadequate production of erythropoietin Excessive hemolysis Hematopoietic stem cell mutation Toxic destruction of stem cells

Inadequate production of erythropoietin

RBC with membrane folded over: * 1/1 Aplastic anemia Iron deficiency anemia Hemoglobin C, hemoglobin SC disease Sickle cell anemia, thalassemia

Hemoglobin C, hemoglobin SC disease

Lazy leukocyte syndrome: * 0/1 Monocyte-macrophage series Neutrophilic series Lymphocytic series Erythrocytic series

Neutrophilic series

The newer clinical instruments for measuring blood clotting are based on: 0/1 Clot elasticity Fibrin adhesion Conduction of impedance of an electrical current by fibrin Changes in optical density

Changes in optical density

other names parasitology

Yves Laure Pimentel · 70問 · 2年前

other names parasitology