11. TRANSPLANTATION IMMUNOLOGY

Yves Laure Pimentel · 70問 · 2年前

通報

問題一覧

TRANSPLANT TO SAME INDIVIDUAL

Autograft

SAFEST TRANSPLANT

Autograft

TRANSPLANT BET. TWINS

Syngeneic graft/isograft

BET. 2 INDI., SAME SPECIE

Allograft

TWO DIFFERENT INDIVIDUALS AND SPECIES

Xenograft/heterograft

CD8+GRAFT CELL -> CELL DEATH

Direct Recognition

CD8+GRAFT CELL -> CELL DEATH

Indirect Recognition

CD4+APC W/ MHC II -> CYTOKINES

Indirect Recognition

DONORS CELL DESTROY THE RECIPIENTS TISSUE

GRAFT VS HOST DISEASE

RESULT IF NOT COMPATIBLE

GRAFT REJECTION

RECIPENT DESTROY THE TRANSPLANT TISSUE, RECIPIENT REACT IF NOT COMPATIBLE

GRAFT REJECTION

sites accessible to the immune system in the recipient ARE SUSCEPTIBLE TO

GRAFT REJECTION

Regulator and Effector of graft rejection:

CELL MEDIATED

– safest transplant

Cornea

Active infection- THE MOST IMPORTANT EXCLUSION IN THIS ORGAN

Heart

________ – primary method for monitoring organ rejection in Heart

Endomyocardial BIOPSY

– standard modality for tx of aortic and mitral valve defect

Xenogenic valve replacement

Sources: bovine and porcine

Heart Valves

Heart Valves Sources:

bovine and porcine

Usually transplanted with other organ. Patient w/ short gut syndrome

Intestine

Donor: stable cardiopulmonary status and liver function

Intestine

strongest assoc. between Tranplant survival

Kidney- HLA D (DR,MB,MT)

most common transplant

Kidney-

Kidney- ref. lab

NKTI NATIONAL KIDNEY TRANSPLANT INSTITUTE

No need for HLA typing

Liver

– LARGEST group of transplant recipient

Congenital Biliary Atresia

– occurs to 30-50% ptx

Biliary tract fistulae or leak

Biliary tract fistulae or leak – occurs to ?% ptx

30-50%

- Donor and recipient must have the same BRONCHIAL circumference

Lungs

other names parasitology

other names parasitology

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PARASITOLOGY

PARASITOLOGY

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HTMLBE

HTMLBE

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CC - 1 LAB. SAFETY, BASIC UNITS, AND CONVERSION FACTOR

CC - 1 LAB. SAFETY, BASIC UNITS, AND CONVERSION FACTOR

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HISTOPATHOLOGY

HISTOPATHOLOGY

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CC-2 SPECTROPHOTOMETRY

CC-2 SPECTROPHOTOMETRY

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CC-3 ELECTROPHORESIS

CC-3 ELECTROPHORESIS

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AUBF LAB SAFETY

AUBF LAB SAFETY

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CSF 1

CSF 1

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CSF 2

CSF 2

82問 • 2年前

SEMEN 1

SEMEN 1

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SEMEN 2

SEMEN 2

7問 • 2年前

SYNOVIAL FLUID 1

SYNOVIAL FLUID 1

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SYNOVIAL FLUID 2

SYNOVIAL FLUID 2

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Yves Laure Pimentel · 25問 · 2年前

SEROUS FLUID

SEROUS FLUID

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PLEURAL FLUID

PLEURAL FLUID

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PERICARDIAL FLUID

PERICARDIAL FLUID

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PERITONEAL FLUID/ ASCITIC FLUID

PERITONEAL FLUID/ ASCITIC FLUID

30問 • 2年前

Yves Laure Pimentel · 92問 · 2年前

AMNIOTIC FLUID

AMNIOTIC FLUID

92問 • 2年前

Yves Laure Pimentel · 80問 · 2年前

FECALYSIS

FECALYSIS

80問 • 2年前