major component of Alpha 1 band

These are natural antibiotics

protect us againts the oxidative property of Ironw because it binds hemoglobin and it has inverse relationship to intravascular hemolysis

how many % increases of Acute Phase reactants if there is an inflammation

stimulus of APR

parameter and used to monitor inflammation

non specific form of ab

indirect measurement of APR and reacts slowly

major humoral (fluid) component of natural immunity

what is the humoral factor that has enzymatic activity that binds copper; for serum copper measurement

increase when there is inflammation

APR production in the

It triggers inflammation in APR

Are cellular factors of immunity that process and "present" antigens to T cell receptor

C-Reactive Protein: increase AT

C-Reactive Protein hours half life

C-Reactive Protein: Adult:

indicator of acute INFLAMMATION

non specific form of Ab.

used for DIFFERENTIATION between bacterial and viral infection

COMPLEMENT ACTIVATOR

C-Reactive Protein Main Substrate: COMMON CONSTITUENT OF MICROBIAL ENZYMES

Threshold for High Cardiovascular risk

Indirect measure of APR

Direct and quantitative measure of APR

Reacts SLOWLY

Reacts RAPIDLY

Removal of cholesterol (cholesterol-filled macrophages) ? Recycle

Serum Amyloid A:x?,

Increase more in bacterial than viral infection

protease inhibitor (elastase)

Alpha1-antitrypsin –?x, ? hours

Alpha1-antitrypsin DSE

Clot formation, most abundant coag factor, Increase in coronary artery disease (esp.women)

– 20-10x, 24hours

– 2-5x, 24 hours

Haptoglobin – ?x, ? hours

opsonization and lysis

HAPTOGLOBIN IS INVERSELY PROPORTIONAL TO

: 2x, 48-72 hrs -complement activation, opsonin, Ca dependent, recognizes Mannose

Ceruloplasmin used to monitor WHAT disease

used to monitor HODGKINS disease

-associated with HDL cholesterol, and it is thought to play a role in metabolism of cholesterol; by removing cholesterol-filled macrophages at the site of tissue injury, it contributes to the cleaning up of the area.

Series of serum proteins that are normally present and whose overall function is mediations of inflammation

-A trimer that acts as opsonin, which is calcium-dependent

- Recognizes foreign carbohydrates from pathogenic microorganisms

Homologous to C1q

-Major component of the alpha-band when serum is electrophoresed

General inhibitor of proteases released from leukocytes, especially elastase; deficiency of such results to emphysema

-An alpha-2 globulin that primarily binds irreversibly to free hemoglobin released by intravascular hemolysis

-Most abundant coagulation factor; cleaved by thrombin to form fibrin clot

-Principal copper-transporting protein in human plasma

Acts as ferroxidase, oxidizing iron from Fe2+ to Fe3+; this may serves as a means of releasing iron from ferritin for binding to transferrin

Deficiency is associated with wilson's Disease

Ceruloplasmin Deficiency is associated with