ABO Blood Group System

15問 • 1年前

問題一覧

The reactivity of blood group A is confirmed by detecting the presence of which immunodominant sugar molecule? N-acetyl-D-neuraminic acid L-fucose N-acetyl-D-galactosamine N-acetyl-D-glucosamine D-galactose

N-acetyl-D-galactosamine

The mating of parents of which two ABO phenotypes can potentially produce offspring with ALL of the common four blood types? AB and O AB and A AB and B AB and AB A and B

A and B

Bombay phenotype (Oh) individuals may have antibodies with all the following specificities EXCEPT: Anti-A Anti-B Anti-H Anti-O Anti-A,B

Anti-O

Which cells agglutinate most strongly with Ulex europaeus lectin? O and A2 A1 and A2 O and A1B B and A2B A1 and B

O and A2

Immune A and B alloantibodies differ from non-red cell stimulated (naturally occurring) A and B alloantibodies in that the immune antibodies: Are generally IgG rather than IgM Are unable to cross the placenta Can be enhanced in reactivity by incubation at 4oC Cause direct agglutination at room temperature Rarely cause clinical hemolysis

Are generally IgG rather than IgM

Which ABH substances would you expect to find in the saliva of a group A secretor? H only H and A H and B H and O A only

H and A

Which of the following is the best explanation for why the ABO system is the most important blood group system in transfusion safety? It is the only system in which antibodies are normally produced for the antigens an individual lacks ABO antibodies are capable of causing rapid, severe intravascular hemolysis Reactions with ABO antibodies are the most common cause of transfusion-related death ABO antibodies are often implicated in severe hemolytic disease of the fetus and newborn Routine ABO forward and reverse grouping is difficult to interpret and fraught with error

ABO antibodies are capable of causing rapid, severe intravascular hemolysis

A 26 year old pregnant female is being tested prior to a scheduled C-section tomorrow. Her cell grouping (forward typing) is consistent with blood group O, while her serum grouping (reverse grouping or "back-typing") appears to be group A. The most common reason for this type of ABO discrepancy is: She has the Bombay phenotypewrong She is a non-secretor, so her plasma lacks A Clerical errors or a sample mix-up Use of an uncalibrated centrifuge She has undiagnosed acute leukemia (AML)

Clerical errors or a sample mix-up

An ABO discrepancy between forward and reverse grouping owing to weak-reacting or missing antibodies could be BEST explained by which of the following: Patient has a subgroup of blood group A Patient is very old or very young Patient has acquired B phenotype Patient has antibodies to low incidence antigens Patient has antibodies against reagent preservatives

Patient is very old or very young

A blood donor has the genotype hh, AB. What is his apparent red cell phenotype during routine forward and reverse group typing? A B O AB Cannot be determined

Approximately what percentage of group A individuals could be further classified as subgroup A1? 20% 40% 60% 80% 99%

80%

Which of the following statements is TRUE regarding the A2 blood group? Dolichos biflorus lectin agglutinates A2 but not A1 RBC Ulex europaeus lectin will give stronger reactions with A1 than with A2 RBCs A2 RBCs have more H antigen than A1 RBCs If anti-A1 is made by an A2 person, it is usually clinically significant Most A2 individuals have a different form of anti-B than A1 individuals

A2 RBCs have more H antigen than A1 RBCs

Which of the following genes codes for production of the same basic antigen as the gene known as H? O Le Lu Se A

Alert! Completely absurd and unrealistic question coming! The labels have come off of some of the reagent bottles in your transfusion service, so the ABO testing reagents are just sitting there, label-less (and they just look ridiculous!). A new lab scientist is trying to find the anti-B, and he asks, "What color is anti-B?" You reply: "Green" "Orange" "Blue" "Yellow" "Your mother was a hamster and your father smelt of elderberries!"

"Yellow"

Which of the following statements is TRUE regarding Hemolytic Disease of the Fetus/Newborn (HDFN) caused by ABO antibodies? Fetal hemolysis is typically severe It rarely occurs during the first pregnancy It is most common with O mothers and A babies A negative cord blood direct antiglobulin test excludes it It occurs less commonly than Rh HDFN

It is most common with O mothers and A babies

other names parasitology

Yves Laure Pimentel · 70問 · 2年前

other names parasitology