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100問 • 1年前

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The minimum hemoglobin concentration in a fingerstick from a male blood donor is: a 12.0 9/dL (120 g/L) b 12.5 g/dL (125 g/L) c 13.5 g/dL (135 g/L) d 15.0 g/dL. (150 g/L)

b 12.5 g/dL (125 g/L)

Acause for permanent deferral of blood donation is: a diabetes b residence in an endemic malaria region c_ history of jaundice of uncertain cause d_ history of therapeutic rabies vaccine

c_ history of jaundice of uncertain cause

Which of the following prospective donors would be accepted for donation? a 32-year-old woman who received a transfusion in a complicated delivery 5 months previously b 19-year-old sailor who has been stateside for 9 months and stopped taking his anti-malarial medication 9 months previously c 22-year-old college student who has a temperature of 99.2°F (37.3°C) and states that he feels well, but is nervous about donating d 45-year-old woman who has just recovered from a bladder infection and is still taking antibiotics

c 22-year-old college student who has a temperature of 99.2°F (37.3°C) and states that he feels well, but is nervous about donating

Which one of the following constitutes permanent rejection status of a donor? a a tattoo 5 months previously b recent close contact with a patient with viral hepatitis ¢ 2 units of blood transfused 4 months previously d confirmed positive test for HBsAg 10 years previously

d confirmed positive test for HBsAg 10 years previously

According to AABB standards, which of the following donors may be accepted as a blood donor? traveled to an area endemic for malaria 9 months previously spontaneous abortion at 2 months of pregnancy, 3 months previously resides with a known hepatitis patient received a blood transfusion 22 weeks previously

spontaneous abortion at 2 months of pregnancy, 3 months previously

Below are the results of the history obtained trom a prospective female blood donor: age: 16 temperature: 99.0°F (37.2°C) Het: 36% history: tetanus toxoid immunization 1 week previously How many of the above results excludes this donor from giving blood for a routine transfusion? a none b 1 c 2 d 3

b 1

For apheresis donors who donate platelets more frequently than every 4 weeks, a platelet count must be performed prior to the procedure and be at least: a 150 x 103/uL (150 x 109/L) b 200 x 103/uL (200 x 109/L) ¢ 250 x 103/uL (250 x 109/L) d 300 x 103/pL (300 x 109/L)

a 150 x 103/uL (150 x 109/L)

Prior to blood donation, the intended venipuncture site must be cleaned with a scrub solution containing: a hypochlorite b isopropyl alcohol c 10% acetone d_ PVP iodine complex

d_ PVP iodine complex

All donor blood testing must include: a complete Rh phenotyping b anti-CMV testing c direct antiglobulin test d_ serological test for syphilis

_ serological test for syphilis

During the preparation of Platelet Concentrates from Whole Blood, the blood should be: cooled towards 6°C cooled towards 20°-24°C warmed to 37°C heated to 57°C

cooled towards 20°-24°C

The most common cause of posttransfusion hepatitis can be detected in donors by testing for: a anti-HCV b HBsAg ¢ anti-HAV IgM d anti-HBe

b HBsAg

The Western blot is a confirmatory test for the presence of: CMV antibody anti-HIV-1 HBsAg serum protein abnormalities

anti-HIV-1

The test that is currently used to detect donors who are infected with the AIDS virus is: a anti-HBc b anti-HIV 1,2 c HBsAg d ALT

b anti-HIV 1,2

A commonly used screening method for anti-HIV-1 detection is: a latex agglutination b radioimmunoassay (RIA) c thin-layer-chromatography (TLC) d enzyme-labeled immunosorbent assay (ELISA)

d_ enzyme-labeled immunosorbent assay (ELISA)

Rejuvenation of a unit of Red Blood Cells is a method used to: remove antibody attached to RBCs inactivate viruses and bacteria restore 2,3-DPG and ATP to normal levels filter blood clots and other debris

restore 2,3-DPG and ATP to normal levels

A unit of packed cells is split into 2 aliquots under closed sterile conditions at 8 AM. ‘The expiration time for each aliquot is now: a 4PM on the same day b 8 pM on the same day c 8AM the next morning d the original date of the unsplit unit

d the original date of the unsplit unit

A unit of Red Blood Cells expiring in 35 days is split into 5 small aliquots using a sterile pediatric quad set and a sterile connecting device. Each aliquot must be labeled as expiring in: a 6hours b 12 hours c 5Sdays d 35 days

d 35 days

When platelets are stored on a rotator set on an open bench top, the ambient air temperature must be recorded: once a day twice a day every 4 hours every hour

every 4 hours

Which of the following is the correct storage temperature for the component listed? Cryoprecipitated AHF, 4°C Fresh Frozen Plasma (FFP), -20°C Red Blood Cells, Frozen, -40°C Platelets, 37°C

Fresh Frozen Plasma (FFP), -20°C

A unit of Red Blood Cells is issued at 9:00 am. At 9:10 aM the unit is returned to the Blood Bank. The container has not been entered, but the unit has not been refrigerated during this time span. The best course of action for the technologist is to: a culture the unit for bacterial contamination b discard the unit if not used within 24 hours c store the unit at room temperature d record the return and place the unit back into inventory

d record the return and place the unit back into inventory

The optimum storage temperature for Red Blood Cells, Frozen is: a -80°C b -20°C ¢ -12°C d 4c

a -80°C

The optimum storage temperature for Red Blood Cells is: a -80°C b -20°C ¢ -12°C d 4c

d 4c

If the seal is entered on a unit of Red Blood Cells stored at 1°C to 6°C, what is the maximum allowable storage period, in hours? a 6 b 24 c 48 d 72

b 24

The optimum storage temperature for cryoprecipitated AHF is: -20°C -12°C 4C 22°C

-20°C

Cryoprecipitated AHF must be transfused within what period of time following thawing and pooling? a 4 hours b 5 hours c 12 hours d 24 hours

a 4hours

Platelets prepared in a polyolefin type container, stored at 22°-24°C in 50 mL of plasma, and gently agitated can be used for up to: a 24 hours b 48 hours c 3 days d 5 days

d 5 days

The optimum storage temperature for platelets is: a -20°C b -12°C c 4¢ d 22°C

d 22°C

According to AABB standards, Fresh Frozen Plasma must be infused within what period of time following thawing? 24 hours 36 hours 48 hours 72 hours

24 hours

Cryoprecipitated AHF, if maintained in the frozen state at -18°C or below, has a shelf life of: 42 days 6 months 12 months 36 months

12 months

Once thawed, Fresh Frozen Plasma must be transfused within: a 4 hours b 8 hours ¢ 12 hours d 24 hours

d 24 hours

Animportant determinant of platelet viability following storage is: a plasma potassium concentration b plasma pH ¢ prothrombin time d_ activated partial thromboplastin time

b plasma pH

In the liquid state, plasma must be stored at: a 1°-6C b 22°C c 37°C d 56°C

a 1°-6C

During storage, the concentration of 2,3-diphosphoglycerate (2,3-DPG) decreases in a unit of: a Platelets b Fresh Frozen Plasma c Red Blood Cells d Cryoprecipitated AHF

c Red Blood Cells

Cryoprecipitated AHF: is indicated for fibrinogen deficiencies should be stored at 4°C prior to administration will not transmit hepatitis B virus is indicated for the treatment of hemophilia B

is indicated for fibrinogen deficiencies

Which apheresis platelets product should be irradiated? autologous unit collected prior to surgery random stock unit going to a patient with DIC a directed donation given by a mother for her son a directed donation given by an unrelated family friend

a directed donation given by a mother for her son

Irradiation of a unit of Red Blood Cells is done to prevent the replication of donor: a granulocytes b lymphocytes c red cells d platelets

b lymphocytes

Plastic bag overwraps are recommended when thawing units of FFP in 37°C water baths because they prevent: the FFP bag from cracking when it contacts the warm water water from slowly dialyzing across the bag membrane the entry ports from becoming contaminated with water the label from peeling off as the water circulates in the bath

the entry ports from becoming contaminated with water

Which of the following blood components must be prepared within 8 hours after phlebotomy? Red Blood Cells Fresh Frozen Plasma Red Blood Cells, Frozen Cryoprecipitated AHF

Fresh Frozen Plasma

Cryoprecipitated AHF contains how many units of Factor VIII? a 4g b 80 c 130 d 250

b 80

Which of the following blood components contains the most Factor VIII concentration relative to volume? a Single-Donor Plasma b Cryoprecipitated AHF c Fresh Frozen Plasma d Platelets

b Cryoprecipitated AHF

The most effective component to treat a patient with fibrinogen deficiency is: a Fresh Frozen Plasma b Platelets c Fresh Whole Blood d Cryoprecipitated AHF

d Cryoprecipitated AHF

Ablood component prepared by thawing Fresh Frozen Plasma at refrigerator temperature and removing the fluid portion is: a Plasma Protein Fraction b Cryoprecipitated AHF c Factor IX Complex d FP24

Cryoprecipitated AHF

Upon inspection, a unit of platelets is noted to have visible clots, but otherwise appears normal. The technologist should: a issue without concern b filter to remove the clots c centrifuge to express off the clots d quarantine for Gram stain and culture

d quarantine for Gram stain and culture

According to AABB Standards, at least 90% of all Apheresis Platelets units tested shall contain a minimum of how many platelets? a 5.5x 10^10 b 6.5 x 10^10 c 3.0 x 10^11 d 5.0x 10^11

c 3.0 x 10^11

According to AABB Standards, Platelets prepared from Whole Blood shall have at least: a 5.5 x 10^10 platelets per unit in at least 90% of the units tested b 6.5 x 10^10 platelets per unit in 90% of the units tested ¢ 7.5x 10^10 platelets per unit in 100% of the units tested d 8.5 x 10^10 platelets per unit in 95% of the units tested

a 5.5 x 10^10 platelets per unit in at least 90% of the units tested

Which of the following is proper procedure for preparation of Platelets from Whole Blood? a light spin followed by a hard spin b light spin followed by 2 hard spins ¢ 2 light spins d hard spin followed by a light spin

a light spin followed by a hard spin

According to AABB standards, what is the minimum pH required for Platelets at the end of the storage period? a 6.0 b 6.2 c 68 d 7.0

b 6.2

According to AABB standards, Platelets must be: a gently agitated if stored at room temperature b separated within 12 hours of Whole Blood collection ¢ suspended in sufficient plasma to maintain a pH of 5.0 or lower d_ prepared only from Whole Blood units that have been stored at 4°C for 6 hours

a gently agitated if stored at room temperature

A unit of Whole Blood-derived (random donor) Platelets should contain at least: a 1.0x 10^10 platelets b 5.5 x 10^9 platelets c 5.5x 10^11" platelets d 90% of the platelets from the original unit of Whole Blood

b 5.5 x 10^9 platelets

Platelets prepared by apheresis should contain at least: a 1x 10^10 platelets b 3x10^10 platelets c 3x10^11 platelets d 5x 10^11 platelets

c 3x10^11 platelets

Leukocyte-Reduced Red Blood Cells are ordered for a newly diagnosed bone marrow candidate. What is the best way to prepare this product? crossmatch only CMV-seronegative units irradiate the unit with 1,500 rads wash the unit with saline prior to infusion transfuse through a Log^3 leukocyte-removing filter

transfuse through a Log^3 leukocyte-removing filter

Of the following blood components, which one should be used to prevent HLA alloimmunization of the recipient? a_ Red Blood Cells b Granulocytes c Irradiated Red Blood Cells d Leukocyte-Reduced Red Blood Cells

d Leukocyte-Reduced Red Blood Cells

father donating Platelets for his son is connected to a continuous flow machine, which uses the principle of centrifugation to separate Platelets from Whole Blood. As the Platelets are harvested, all other remaining elements are returned to the donor. This method of Platelet collection is known as: a apheresis b autologous c homologous d_ fractionation

a apheresis

To qualify as a donor for autologous transfusion a patient’s hemoglobin should be at least: a 8 g/dL (80 g/L) b 11 g/dL (110 g/L) ¢ 13 g/dL (130 g/L) d 15 g/dL (150 g/L)

b 11 g/dL (110 g/L)

What is/are the minimum pretransfusion testing requirement(s) for autologous donations collected and transfused by the same facility? a ABO and Rh typing only b ABO/Bh type, antibody screen c ABO/Rh type, antibody screen, crossmatch d no pretransfusion testing is required for autologous donations

a ABO and Rh typing only

In a quality assurance program, Cryoprecipitated AHF must contain a minimum of how many, international units of Factor VIII? 60 70 80 90

An assay of plasma from a bag of Cryoprecipitated AHF yields a concentration of 9 international Units ([U) of Factor VIII per mL of Cryoprecipitated AHF If the volume is 9 mL, what is the Factor VIII content of the bag in IU? a 9 b 18 c 27 d 81

d 81

Refer to the following table: Given the most probable genotypes of the parents, which of the following statements best describes the most probable Rh genotypes of the 4 children? a 2 are R1r, 2 are R1R1 b 3 are R1r, is rr ¢ 1 is Ror, 1 is R1r, 2 are R1R1 d lis Ror’, 1 is R1R1, 2 are R1r

a 2 are R1r, 2 are R1R1

The linked HLA genes on each chromosome constitute a(n): allele trait phenotype haplotype

haplotype

An individual’s red blood cells give the following reactions with Rh antisera: anti-D anti-C anti-E anti-c anti-e Rhcontrol 4+ 3+ 0 3+ 3+ 0 The individual’s most probable genotype is: a DCe/DcE b DcE/dce c Dce/dce d DCe/dce

d DCe/dce

A blood donor has the genotype: hh, AB. What is his red blood cell phenotype? a A b B c O d AB

c O

An individual has been sensitized to the k antigen and has produced anti-k. What is her most probable Kell system genotype? a KK b Kk c kk d K0K0

a KK

Given the following typing results, what is this donor’s racial ethnicity? Le(a—b-); Fy(a—b-); Js(a+b+) a African American b Asian American c Native American d Caucasian

a African American

A mother has the red cell phenotype D+C+E-c-e+ with anti-c (titer of 32 at AHG) in her serum. The father has the phenotype D+C+E-c+e+. The baby is Rh-negative and not affected with hemolytic disease of the newborn. What is the baby’s most probable Rh genotype? a r1r1 b r1r c R1R1 d R1r

a r1r1

In an emergency situation, Rh-negative red cells are transfused into an Rh-positive person of the genotype CDe/CDe. The first antibody mest likely to develop is: a anti-c b anti-d c anti-e d anti-E

a anti-c

Most blood group systems are inherited as: sex-linked dominant sex-linked recessive autosomal recessive autosomal codominant

autosomal codominant

The mating of an Xg(a+) man and an Xg(a-) woman will only produce: a Xg(a-) sons and Xg(a-) daughters b Xg(a+) sons and Xg(a+) daughters c Xg(a-) sons and Xg(a+) daughters d Xg(a+) sons and Xg(a-) daughters

c Xg(a-) sons and Xg(a+) daughters

Refer to the following data: a R0R0 b R1r' c R0r'' d R1R2

a R0R0

The red cells of a nonsecretor (se/se) will most likely type as: Le{a-b-) Le(atb+) Le(a+b-) Le(a-b+)

Le{a-b-)

Which of the following phenotypes will react with anti-f? a rr b R1R1 c R2Ro d R1R2

a rr

patient's red blood cells gave the following reactions: The most probable genotype of this patient is: a R1R2 b R2r” c Rzr d RzRz

a R1R2

Anti-N is identified in a patient’s serum. If random crossmatches are performed on 10 donor units, how many would be expected to be compatible? a 0 b 3 c 7 d 10

b 3

A woman types as Rh-positive. She has an anti-c titer of 32 at AHG. Her baby has a negative DAT and is not affected by hemolytic disease of the newborn. What is the father’s most likely Rh phenotype? a rr b r"r c R1r d R2r

a rr

Which of the following red cell typings are most commonly found in the African American donor population? a Lu(a-b-) b Jk(a-b-) c Fy(a-b-) d K-k-

c Fy(a-b-)

Four units of blood are needed for elective surgery. The patient’s serum contains anti-C, anti-e, anti-Fya and anti-Jkb. Which of the following would be the best source of donor blood? a test all units in current stock b test 100 group O, Rh-negative donors c test 100 group-compatible donors d rare donor file

d rare donor file

A donor is tested with Rh antisera with the following results: anti-D anti-C anti-E anti-c anti-e Rh control + + 0 + + 0 What is his most probable Rh genotype? a R1R1 b R1r c Ror d R2r

b R1r

A family has been typed for HLA because 1 of the children needs a stem cell donor. Typing results are listed below: father: A1,3;B8,35 mother: A2,23;B12,18 child #1: A1,2;B8,12 child #2: A1,23;B8,18 child #3: A3,23,B18,? What is the expected B antigen in child #3? a A1 b A2 c B12 d B35

d B35

Which of the following is the best source of HLA-compatible platelets? a mother b father c siblings d cousins

c siblings

A patient is group O, Rh-negative with anti-D and anti-K in her serum. What percentage of the general Caucasian donor population would be compatible with this patient? a 0.5 b 2.0 c 3.0 d 6.0

d 6.0

The observed phenotypes in a particular population are: Phenotype Number of persons Jk(a+b-) 122 Jk(a+b+) 194 Jk(a-b+) 84 What is the gene frequency of Jk* in this population? a 0.31 b 0.45 c 0.55 d 0.60

c 0.55

In a random population, 16% of the people are Rh-negative (rr). What percentage of the Rh-positive population is heterozygous for r? a 36% b 48% c 57% d 66%

b 48%

In relationship testing, a “direct exclusion” is established when a genetic marker is: a absent in the child, but present in the mother and alleged father b absent in the child, present in the mother and absent in the alleged father c present in the child, absent in the mother and present in the alleged father d present in the child, but absent in the mother and alleged father

d present in the child, but absent in the mother and alleged father

Relationship testing produces the following red cell phenotyping results: ABO Rh alleged father: B D+C-c+E+e- mother: O D+C+E-c-e+ child: O D+C+E-c+e+ What conclusions may be made? a there is no exclusion of paternity b paternity may be excluded on the basis of ABO typing c paternity may be excluded on the basis of Rh typing d paternity may be excluded on the basis of both ABO and Rh typing

c paternity may be excluded on the basis of Rh typing

In a relationship testing case, the child has a genetic marker that is absent in the mother and cannot be demonstrated in the alleged father. What type of paternity exclusion is this known as? a indirect b direct ¢ prior probability d Hardy-Weinberg

b direct

A patient is typed with the following results: The most probable reason for these findings is that the patient is group: a O; confusion due to faulty group O antiserum b O; with an anti-A1 c Ax; with an anti-A1 d A1; with an anti-A

c Ax; with an anti-A1

Human blood groups were discovered around 1900 by: Jules Bordet Louis Pasteur Karl Landsteiner PL Mollison

Karl Landsteiner

Cells of the Ag subgroup will: a react with Dolichos biflorus b bE- with anti-A c give a mixed-field reaction with anti-A,B d bE- with anti-H

c give a mixed-field reaction with anti-A,B

The enzyme responsible for conferring H activity on the red cell membrane is alpha-: a_ galactosyl transferase b N-acetylgalactosaminyl transferase c L-fucosyl transferase d N-acetylglucosaminyl transferase

c L-fucosyl transferase

Even in the absence of prior transfusion or pregnancy, individuals with the Bombay phenotype (Oh) will always have naturally occurring: anti-Rh anti-Ko anti-U anti-H

anti-H

‘The antibody in the Lutheran system that is best detected at lower temperatures is: anti-Lua anti-Lub anti-Lu3 anti-Lu2ab

anti-Lua

Which of the following antibodies is neutralizable by pooled human plasma? anti-Kn^a anti-Ch anti-Yk^a anti-Cs^a

anti-Ch

Anti-Sd^a is strongly suspected if: the patient has been previously transfused the agglutinates are mixed-field and refractile the patient is group A or B only a small number of panel cells are reactive

the agglutinates are mixed-field and refractile

HLA antibodies are: a naturally occurring b induced by multiple transfusions c directed against granulocyte antigens only d frequently cause hemolytic transfusion reactions

b induced by multiple transfusions

Genes of the major histocompatibility complex (MHC): code for HLA-A, HLA-B, and HLA-C antigens only are linked to genes in the ABO system are the primary genetic sex-determinants contribute to the coordination of cellular and humoral immunity

contribute to the coordination of cellular and humoral immunity

Isoimmunization to platelet antigen HPA-1a and the placental transfer of maternal antibodies would be expected to cause newborn: a_ erythroblastosis b leukocytosis ¢ leukopenia d thrombocytopenia

d thrombocytopenia

Saliva from which of the following individuals would neutralize an auto anti-H in the serum of a group A, Le(a-b+) patient? a group A, Le(a-b-) b group A, Le{atb-) c group O, Le(a+b-) d_ group O, Le(a-b+)

d_ group O, Le(a-b+)

Inhibition testing can be used to confirm antibody specificity for which of the following antibodies? anti-Lua anti-M anti-Le^a anti-Fya

anti-Le^a

Which of the following Rh antigens has the highest frequency in Caucasians? D E c e

Anti-D and anti-C are identified in the serum of a transfused pregnant woman, gravida 2, para 1. Nine months previously she received Rh immune globulin (RhIG) after delivery. Tests of the patient, her husband, and the child revealed the following: The most likely explanation for the presence of anti-C is that this antibody is: a actually anti-C^w b from the RhIG dose c actually anti-G d naturally occurring

c actually anti-G

100

The phenomenon of an Rh-positive person whose serum contains anti-D is best explained by: ’ a gene deletion b missing antigen epitopes ¢ trans position effect d_ gene inhibition

b missing antigen epitopes

other names parasitology

Yves Laure Pimentel · 70問 · 2年前

other names parasitology