Rh Blood Group System Quiz

15問 • 1年前

問題一覧

Name the three genes responsible for the production of Rh antigens. RHAG, RH1, and RH2 RHAG, DCE, and dce RHAG, RHD, and RHCE RHD, RHCc, and RHEe RHD, RHCE, and RHce

RHAG, RHD, and RHCE

Which of the following is TRUE regarding the weak D phenotype? Occurs when the D antigen has missing or abnormal parts (epitopes) Is easily distinguished from partial D by serologic testing Was traditionally identified by an indirect antiglobulin test Are usually at risk for making anti-D if exposed to D+ blood Most often results from inheritance of the R0r' genotype

Was traditionally identified by an indirect antiglobulin test

Which of the following red blood cell abnormalities is associated with the Rhnull phenotype? Stomatocytes Ovalocytes Acanthocytes Spherocytes Schistocytes

Stomatocytes

A patient has the following Rh phenotype: D:+ C:+ c:+ E:+ e:+ What is her most likely Rh genotype? R1R1 R1R2 R2r R0ry R2r"

R1R2

A Caucasian patient has the following Rh phenotype: D:+ C:+ c:+ E:- e:+ Which of the following is his most likely Rh genotype? R1R0 R1r R0r R1R1 R0r' ryr'

R1r

An African-American patient has the following Rh phenotype: D:+ C:+ c:+ E:+ e:+ f:– Which of the following is her most likely Rh genotype? R1R2 R0Rz R2r' Rzr R0ry

R1R2

An African-American male potential blood recipient has the following Rh phenotype: D:+ C:+ E:– c:+ e:+ Which of the following is his most likely genotype? R1r R1R2 R0r' Rzry R1R0

R1R0

35 year old O-negative male trauma patient receives a transfusion of two units of O-positive red blood cells before his blood type is known. After his typing is completed, he is switched to O-negative and he receives 6 additional type-specific RBC units. He survives and is transferred to the surgical ICU. Which of the following is TRUE regarding his situation? He has an 80% chance of forming anti-D He is at high risk for an acute hemolytic transfusion reaction Blood bank case review is needed to find the reason for this error He should immediately be given 20 vials of Rh Immune Globulin (RhIG) He is unlikely to develop delayed hemolysis

He is unlikely to develop delayed hemolysis

What percentage of blood specimens derived from those of European descent will have a positive agglutination result with the anti-c reagent? 15% 35% 50% 80% 100%

80%

Which alloantibody is most likely to be produced if a patient that has the Rh genotype of R1R1 is transfused with red blood cells that have an Rh genotype of R0R0? Anti-D Anti-C Anti-c Anti-E Anti-e

Anti-c

A 63 year old male presents with a positive antibody screen and clinical and serologic findings consistent with warm autoimmune hemolytic anemia. In addition, the reference lab technologist also identifies an antibody that reacts stronger when the test RBCs are D-positive. The supervisor suggests the technologist consider anti-LWa in addition to anti-D. Which of the following TWO techniques will MOST assist in differentiating between these two antibodies? Ficin/Papain treatment: LWa destroyed, D resistant D-positive cord cells: anti-LWa negative, anti-D reactive Adsorption/elution with D-negative RBCs: Anti-LWa detected, anti-D not detected Test RBCs treated with 0.2 M DTT: Anti-Lwa strongly reactive, anti-D nonreactive Test RBCs from pregnant donor: Anti-LWa stronger, anti-D weaker

Adsorption/elution with D-negative RBCs: Anti-LWa detected, anti-D not detected

In which of the following groups is Weak D testing required if the initial D typing results appear negative? Routine testing of pregnant female blood recipients Rh typing of allogeneic (volunteer) whole blood donors Pretransfusion testing for sickle cell anemia patients Pretransfusion testing for cardiac surgery patients Confirmatory testing of D-negative RBC by a transfusion service

Rh typing of allogeneic (volunteer) whole blood donorscorrect Pretransfusio

Which of the following is TRUE about Anti-D? It is primarily the IgG isotype rather than IgM It binds complement efficiently, leading to efficient hemolysis It causes hemolysis with prominent schistocyte formation It does not react with D positive cells treated with ficin It does not react with D positive cells treated with dithiothreitol (DTT)

It is primarily the IgG isotype rather than IgM

Anti-G will react with red blood cells of each of the following phenotypes except: D+C- D-C+ D-C- D+C+ rG

D-C-

If a patient had a positive direct antiglobulin test (DAT) with Anti-IgG, what would happen if you performed a Weak D test on the patient cells? A false-positive result A false-negative result An indeterminate result A valid test result An invalid Rh control test

A false-positive result

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Yves Laure Pimentel · 64問 · 2年前

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