IMMUNOHEMATOLOGY 3

22問 • 2年前

問題一覧

9. All of the following are required tests on donor blood, except: * 0/1 A. HBsAg B. Anti-CMV C. HIV-1 D. Anti-HTLV I/II

B. Anti-CMV

10. Which of the following bands would constitute a positive Western Blot result for HIV? * 1/1 A. p24, gp41, p17 B. p55, gp120, p51 C. gp160, p31, p56 D. p24, p30, p55

A. p24, gp41, p17

1. Is there a discrepancy between the following blood typing and secretor study results? * 1/1 A. No problem, the sample is from a group A secretor B. Blood types as A and saliva types as B C. Blood types as A, but the secretor study is inconclusive D. No problem, the sample is from a group A nonsecretor

A. No problem, the sample is from a group A secretor

2. What is the best course of action given the following test result? (Assume the patient has not been transfused recently.) * 0/1 A. Nothing, typing is normal B. Type patient cells with anti-A1 lectin and type serum with A2 cells C. Retype patient cells; type with anti-H and anti-A,B; use screen cells or A2 cells on patient serum; run patient autocontrol D. Wash patient cells four times with saline; then repeat the forward type

C. Retype patient cells; type with anti-H and anti-A,B; use screen cells or A2 cells on patient serum; run patient autocontrol

3. The following results were obtained on a 41-year-old female: Due to the discrepant reverse grouping, a panel was performed on patient serum revealing the presence of anti-M. How can the reverse grouping be resolved? * 0/1 A. Repeat the reverse grouping with a 10-minute incubation at room temperature B. Repeat the reverse grouping using A1 cells that are negative for M antigen C. Repeat the reverse grouping using A1 cells that are positive for M antigen D. No further work is necessary

B. Repeat the reverse grouping using A1 cells that are negative for M antigen

B. Perform a saline replacement for crossmatching

5. The following results were obtained on a 51-year-old male with hepatitis C: Anti-A = 4+ Anti-B = 4+ Anti-D = 3+ A1 cells = 0 B cells = 0 What should be done next? * 0/1 A. Retype the patient’s sample to confirm group AB positive B. Repeat the Rh typing C. Run a saline control in forward grouping D. Report the patient as group AB, Rh positive

C. Run a saline control in forward grouping

6. An Rh phenotyping shows the following results: Anti-D = 4+ Anti-C = 2+ Anti-E = 0 Anti-c = 0 Anti-e = 3+ What is the most likely Rh genotype? * 0/1C. R1R1 A. R1r’ B. R0r C. R1R1 D. R1r

C. R1R1

7. An obstetric patient, 34 weeks pregnant, shows a positive antibody screen at the indirect antiglobulin phase of testing in screening cells I and II; screening cell III was negative. She is group B, Rh negative. This is her first pregnancy. She has no prior history of transfusion. What is the most likely explanation for the positive antibody screen? * 0/1 A. She has developed an antibody to fetal RBCs B. She probably does not have antibodies because this is her first pregnancy, and she has not been transfused; check for technical error C. She received an antenatal dose of RhIg D. Impossible to determine without further testing

C. She received an antenatal dose of RhIg

8. A patient’s serum contains a mixture of antibodies. One of the antibodies is identified as anti-D. Anti-Jka or anti-Fya and possibly another antibody are present. What technique(s) may be helpful to identify the other antibody(s)? * 1/1 A. Enzyme panel; select cell panel B. Thiol reagents C. Lowering the pH and increasing the incubation time D. Using albumin as an enhancement medium in combination with selective adsorption

A. Enzyme panel; select cell panel

9. An anti-M reacts strongly through all phases of testing. Which of the following techniques would not contribute to removing this reactivity so that more clinically significant antibodies may be revealed? * 0/1 A. Acidifying the serum B. Prewarmed technique C. Adsorption with homozygous cells D. Testing with enzyme-treated RBCs

A. Acidifying the serum

10. The reactivity of an unknown antibody could be anti-Jka, but the antibody identification panel does not fit this pattern conclusively. Which of the following would not be effective in determining if the specificity is anti-Jka? * 0/1 A. Testing with enzyme-treated cells B. Select panel of homozygous cells C. Testing with 2-aminoethylisothiouronium bromide (AET)–treated cells D. Increased incubation time

C. Testing with 2-aminoethylisothiouronium bromide (AET)–treated cells

11. A cold-reacting antibody is found in the serum of a recently transfused patient and is suspected to be anti-I. The antibody identification panel shows reactions with all cells at room temperature, including the autocontrol. The reaction strength varies from 2+ to 4+. What procedure would help to distinguish this antibody from other cold-reacting antibodies? * 1/1 A. Autoadsorption technique B. Neutralization using saliva C. Autocontrol using ZZAP reagent-treated cells D. Reaction with cord blood cells

D. Reaction with cord blood cells

12. An antibody identification panel reveals the presence of anti-Leb and a possible second specificity. Saliva from which person would best neutralize the Leb antibody? * 1/1

13. The automated blood bank analyzer does not detect weak forms of D antigen. Why would running type and screens on the analyzer prevent a patient with a weak D phenotype from forming anti-D? * 0/1 A. Weak D persons cannot form anti-D B. The analyzer would show the sample as Rh negative; the patient would receive Rh-negative blood C. The analyzer would show the sample as Rh positive; the patient would receive Rh-positive blood D. A and C

B. The analyzer would show the sample as Rh negative; the patient would receive Rh-negative blood

14. A cord blood workup was ordered on baby boy Jones. The mother is O negative. Results on the baby are as follows: Anti-A = 4+ Anti-B = 0 Anti-A, B = 4+ Anti-D = 0 DAT (poly) = 2+ The test for weak D on the baby was positive at the AHG phase. Is the mother an RhIg candidate? * 1/1 A. No, the baby is Rh positive B. Yes, the baby’s Rh type cannot be determined because of the positive DAT result C. No, the baby is Rh negative D. Yes, the mother is Rh negative

B. Yes, the baby’s Rh type cannot be determined because of the positive DAT result

15. RBCs from a recently transfused patient were positive on DAT when tested with anti-IgG. Screen cells and a panel performed on a patient’s serum showed very weak reactions with inconclusive results. What procedure could help to identify the antibody? * 0/1 A. Elution followed by a panel on the eluate B. Adsorption followed by a panel on the adsorbed serum C. Enzyme panel D. Antigen typing the patient’s RBCs

A. Elution followed by a panel on the eluate

16. A patient types as O positive. All three screening cells and RBCs from two O-positive donor units show agglutination after incubation at 37°C and increase in reactivity at the IAT phase of testing. What action should be taken next? * 0/1 A. Perform an autocontrol and DAT on the patient B. Perform an enzyme panel C. Perform an elution D. Choose another 2 units and repeat crossmatching

A. Perform an autocontrol and DAT on the patient

17. Four units of blood are ordered for a patient. Blood bank records are checked and indicate that 5 years ago this patient had an anti-Jkb. What is the next course of action? * 0/1 A. Antigen type units for the Jkb antigen, and only crossmatch units positive for Jkb B. Antigen type units for the Jkb antigen, and only crossmatch units negative for Jkb C. Randomly pull 4 units of blood that are ABO compatible, and perform crossmatching D. Perform IS crossmatching on 4 Jkb-negative units

B. Antigen type units for the Jkb antigen, and only crossmatch units negative for Jkb

18. A 56-year-old patient diagnosed with colon cancer demonstrates a positive antibody screen in all three screen cells at the AHG phase. The panel study shows 10 cells as positive as well as the autocontrol at the AHG phase. The reactions varied from 1+ to 3+. This patient had a history of receiving 2 units of blood approximately 1 month ago. What should be done next? * 1/1 A. Perform a DAT on patient cells B. Perform an autoadsorption C. Perform an alloadsorption D. Issue O-negative cells

C. Perform an alloadsorption

19. A 33-year-old maternity patient has blood drawn for a type and screen at 36 weeks’ pregnancy. The following results are found on the automated blood bank analyzer: The reference laboratory identified anti-P1 in the patient plasma by using enzyme techniques. How could the ABO discrepancy be solved? A. Wash the patient’s RBCs, and repeat the forward grouping B. Test the patient’s plasma against A2 cells C. Warm the patient’s plasma at 37°C for 10 minutes, and repeat the reverse grouping D. Treat the A1 cells with DTT, and repeat the reverse grouping

C. Warm the patient’s plasma at 37°C for 10 minutes, and repeat the reverse grouping

20. An O-negative mother with no record of any previous pregnancies gives birth to her first child, a B-positive baby. The baby’s DAT is weakly positive, and the saline control is negative. The antibody screen is also negative. The baby appears healthy but after 2 days develops mild jaundice, which is treated with phototherapy. After 4 days in the hospital, the baby goes home, without complications. What is the most likely explanation for the weakly positive DAT result? * 1/1 A. Technical error B. A low-titer anti-D C. Immune anti-B from the mother D. A maternal antibody against a low-incidence antigen

C. Immune anti-B from the mother

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Yves Laure Pimentel · 64問 · 2年前

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