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100問 • 1年前

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問題一覧

Analyze and select the basic product formulation for a tablet.

Active Ingredient, Diluent or Filler, Binder, Disintegrant, Lubricant

Select the oral dosage form, which contains one or more active ingredients dissolved in a suitable base.

Oral Solution

Which of the following statements is correct regarding oral solutions?

Oral pharmaceutical solutions are usually formulated so that the patient receives the usual dose in a conveniently administered volume, such as 5 mL (1 tsp), 10 mL, or 15 mL (1 tbsp).

Select the undesirable characteristic of a dispersed phase of a suspension:

Enhances crystal growth formation

Which of the following is considered an undesirable quality of a suspension?

Suspended particles settle rapidly

Which of the following is a disadvantage characteristic of suspension?

Formation of a compact when the particles eventually settle

Which of the following statement is true regarding suspension?

Suspensions are chemically more stable than solutions.

Select the appropriate procedure to produce aesthetically pleasing suspension:

Add an amount of flocculating agent that will bring about a sedimentation volume equal to 1

First pharmaceutical product of recombinant DNA technology:

Human insulin

Capsule shaped compressed tablet that allows the coated product to be about one third smaller than a capsule filled with an equivalent amount of powder.

Gelatin coated tablet

Classify the medical device: Pacemaker

Class III

SPF

Sun protection factor

Amphoteric surfactants:

Betaine

Select the principal category to which ethyl cellulose belong:

Tablet Binder

Classify clay, silica gel, colloids, metals, activated charcoal, activated alumina as a pharmaceutical excipient:

Adsorbent

Classify glycerin, honey, glucose syrup, egg yolk, sugar alcohols as a pharmaceutical excipient:

Humectant

The following pair are coarse dispersions

Emulsion and suspension

Antifoaming agent:

Castor Oil

Identify the components of yellow ointment:

Yellow wax, yellow petrolatum

Which of the following are used as pharmaceutical ointment bases? I. Lanolin II. Mineral Oil III. Petrolatum IV. Glycerin

I, III

Which of the following statement correctly describe oleaginous ointment bases? I. They include fixed oils of vegetable origin, fats from animals and semisolid HC obtained from petroleum II. Vegetable oils and animal fats have lower water-absorbing capacity III. Vegetable oils raise the melting point of ointments IV. Oleaginous ointment bases are excellent emollients

I, II, IV

Compute for the volume of alcohol to be added to preserve the prescription below. Rx Active drug 5mL Other Drug solids 3 mL Glycerin 15 mL Sucrose 25 g Ethanol 95% q.s Purified water, q.s. 100mL

6.21 mL

Which of the following is correctly matched?

Liniments – Oleaginous

Select the statements that best described syrups as diluting agents: I. Syrups are useful as diluting agents for water soluble drugs II. Syrups act both as solvents and flavoring agents III. Glycyrrhiza Syrup is an excellent vehicle for saline substances because of its colloidal properties, sweet flavor and licorice taste IV. Aromatic Eriodictyon Syrup is the diluting agent of choice for masking taste of urea

I, II, III

Water obtained by distillation, ion- exchange treatment, reverse osmosis or any other suitable process; contains no added substance; and NOT used in preparations intended for parenteral administration:

Purified Water

Which is not an ideal characteristic of a suppository base?

Remains stable in rectal fluids

Find the incorrect statement about theobroma oil:

It is a naturally occurring alkaloid.

Identify cosmetics which are regulated as a drugs:

Lip Balms, Mouthwashes, Antiperspirants, Diaper Ointments

Use of potassium diformate in veterinary medicine:

Strong Antimicrobial

Select the category of emulsifiers or stabilizers that are used primarily as thickening agents and stabilizers for oil in-water emulsions of certain lotions and ointments for external use

HMW alcohols

Method of preparing powders that consists of enclosing the powder container, which rotates and mixes the powder ingredients:

Tumbling

Preservatives interfere with microbial growth and metabolism through one or more of these mechanisms, EXCEPT________:

Reversible protein precipitation

Which sterilization method allows the sterilization of packaged finished products that are ready for shipment because sterilizing material permeates sealed plastic films and cartons?

Gas Sterilization

Identify the colorant not obtained from a biological source:

Nitroso-Dyes

Reason why granules or coarse particles is preferred over fine powders in effervescent preparations.

Decrease dissolution leading to a less violent effervescence.

Defined as the breaking of tablet edges, while the tablet leaves the press or during subsequent handling and coating operations:

Chipping

Types of suppositories: I. Urethral III. Rectal II. Vaginal IV. Oral

I, II and III

Which of the following is a suspension?

Magaldrate

Arrange the following steps of sugarcoating process: I. Color coating IV. Polishing II. Sealing V. Subcoating III. Smoothing

II-V-III-I-IV

Select the appropriate remedy for a capsule defect where the active ingredient prescribed dissolves in an acid medium:

Coat the capsules with polyvinyl acetate phthalate.

This step allows the flavor and odor of a solution to enhance:

Aging

Range of sodium ion concentration in a TPN preparation:

100 – 120 mEq

Determine the effect of overwetting to resulting granules:

Granules will be hard

Sodium bisulfite

Antioxidant

Pharmaceutical glass that is composed of relatively high proportions of sodium oxide and calcium oxide; has a relatively lower concentration of migratory oxides; considered to be of relatively good chemicals resistance for only one use; and suitable for solutions that are buffered and have a pH below 7 and are not reactive with the glass:

Type II

This explains the erratic motion of colloid

Brownian motion

The following formula is used in preparing CT Acetaminophen using wet granulation method. Each tablet contains: Acetaminophen ………… 300 mg PVP………………………………..… 22.5 mg Lactose…………………….…….61.75 mg Alcohol (200 proof)……….. 4.5 mL Stearic acid………………..……. 9.0 mg Talc……………………………………. 13.5 mg Corn starch…………………..43.25 mg To make 10,000 tablets, calculate the amount of PVP to be weighed (g):

225 g

Tablets which have a smooth, rapid disintegration when chewed or allowed to dissolve in the mouth, have a creamy base, usually of specially flavored and colored mannitol.

Chewable tablet

Constitutive property

Refractive index

Classify the following techniques to its corresponding flavoring methodology: Use of menthol to anesthetized taste buds

Physiological

Identify the forces that account for the solubility of iodine in a solution of KI:

Ion-Dipole, Ion- Induced Dipole Forces

Which of the following is the most stable form of chelates?

5- to 6-membered rings

Identify the Law/ Principles which states that when the reaction is reversible, delta S=0:

Gibbs Free Energy

Find the classification of Complexes:

Metal Complexes, Organic Complexes, Inclusion/Occlusion Compounds

Ethylenediamineteatraacetic acid is a:

Hexadentate

Identify the statement/mathematical expression, which does NOT express the First Law of Thermodynamics:

∆ E = EB + EA

Select the concept that explains the thermodynamics state of a perfect crystal at absolute zero:

3rd Law of Thermodynamics

The HLB system I. Each surface-active agents is assigned an HLB value which is indicative of the substance’s polarity II. HLB values range from 1-40 III. Substances that are highly polar or hydrophilic have been assigned higher numbers IV. In using the HLB concept in the preparation of an emulsion, one selects emulsifying agents having higher or lower HLB values as the oleaginous phase of the emulsion

I, II, III

Surfactants: I. Wetting agents aids in attaining contact between solid particles and liquids II. Emulsifying agents reduce interfacial tension between oil and water, resulting in minimizing surface energy through the formation of globules III. Detergents reduce the surface tension and aid in wetting the surface and the dirt IV. Solubilizing agents have HLB values from 3-6

I, II, III

HLB values I. Materials that are hydrophilic have been assigned higher numbers than those that are less polar and more lipophilic II. Surface-active agents with HLB values 3-6 are greatly hydrophilic and produce oil-in-water emulsion III. Surface active agents with HLB 8-18 produce oil-in-water emulsions IV. The usual range of HLB values for surface-active agents is between 1-20

I, III, IV

Adsorption I. When molecules and ion are partitioned in favor of the interface, the phenomenon in called positive adsorption. II. An example of absorption is taking up of water by a sponge. III. When the molecules of a liquid or gas penetrate into the capillary spaces of the medium, this phenomenon is called absorption IV. An example of absorption is when concentration of alkaloid molecules attaches on the surface of clay

I, II, III

Select the viscometers which can be used for both Newtonian and Non-Newtonian system:

Cup and Bob, Cone and Plate

Select the Non-Newtonian liquids

Tobramycin, Chloramphenicol Palmitate Suspension

Analyze and select the factor that governs the degree of repulsion in systems containing dispersed particles.

Electrokinetic Potential

A prescription requires 100 mL of a 1% solution of apomorphine hydrochloride (MW 312.79) that is isotonic with blood serum. The freezing point lowering of the drug is 0.08oC and that of 0.9 percent sodium chloride is 0.52oC. How many grams of sodium chloride will be added to make 100 mL of isotonic solution?

0.76 g

Calculate the approximate E value of boric acid. (MW 61.84, Liso 1.8)

0.5

Strongest intermolecular force

Hydrogen bond

Select the statement that characterizes association colloids:

Micelles are aggregates of molecules or ions of the substance dissolved in the dispersion medium.

Identify the property which is used to determine the molecular weight of colloids:

Light Scattering

Find the statement that is INCORRECT regarding the influence of some factors on the solubility of solids:

The configuration of a solid molecule has NO effect on its solubility.

Select the statement that BEST describes solubility of solids in liquids:

The solubility of a solid in an ideal solution depends on the temperature, melting point of the solid and molar heat of fusion.

Lyophilic colloids

Gelatin

The difference between the surface tensions of the liquid/vapor and solid/vapor and that of the solid/liquid:

Work Of Adhesion

Molecules and ions that are adsorbed at interfaces are termed as:

AOTA

Defined as the difference in potential between the actual surface and the electroneutral region of the solution:

both Nernst Potential and Electrothermodynamic Potential

The following are true about Brownian movement except:

The velocity of the particles decreases with decreasing particle size

The following are true about viscosity of colloidal dispersions except:

Spherocolloids form dispersions of relatively high viscosity

Hypertonic solution:

Make the following preparation solution isotonic: Phenacaine hydrochloride 0.06 g Boric acid 0.30 g Sterilized distilled water q.s. 100.0 mL (E for boric acid = 0.50, E for phenacaine hydrochloride = 0.20)

18 mL

If the surface tension of water γS is 72.8 dynes/cm at 20°C, the surface tension of benzene, γL, is 28.9 dynes/cm, and the interfacial tension between benzene and water, γLS, is 35.0 dynes/cm, Following equilibration, γS′ is 62.2 dynes/cm and γL′ is 28.8 dynes/cm. What is the final spreading coefficient?

– 1.6 dynes/cm

The following are true about the stability of colloids except:

NOTA

The following are true about chelates except:

When the ligand provides one group for attachment to the central ion, the chelate is called bidentate

The following are true about organic molecular complexes except:

NOTA

The following are true about drug complexes except:

NOTA

The following are true about inclusion/ occlusion compound complexes except:

NOTA

A sample of calcium oxide powder with a true density of 3.203 and weighing 131.3 g was found to have a bulk volume of 82.0 cm3 when placed in a 100 mL graduated cylinder. Calculate the porosity.

50%

Liso of non-electrolytes

1.9

Select the statement that best describes “Refilling of a Prescription”:

Dispensing the remaining balance of medicines ordered in the prescription

Violative prescription:

Only the brand name is written on the prescription, with the phrase, “No substitution”

Agency where the pharmacist must report the destruction of dangerous drugs?

PDEA

A person affixing “RPh” title on his/her name violates the:

Philippine Pharmacy Act

What are the components of the “Essential Health Benefit Package” based on the Universal Health Care Law:

Primary care, medicines, diagnostic and laboratory tests, preventive, curative, rehabilitative services

Applicable S-license for the retail of DP/s containing Table I Controlled Chemical/s:

S-1

Category A are: Pharmaceutical establishments/outlets where the direct and immediate control and supervision of a duly registered and licensed pharmacist is required, per establishment, whether in-store or online, including:

NOTA

Magna Carta for Disabled Persons

RA 7277

Legal basis of Immunizing Pharmacist Certification

Professional Regulatory Board of Pharmacy Resolution No. 05 series of 2021

Which of the following statement is correct regarding the oversight role and functions of pharmacists in Category B establishments: I. The supervising pharmacist must be physically present in the establishment/ outlet for a minimum of two (2) hours a week II. The location of each establishment/ outlet which the pharmacist supervises must be within the same provincial LGU within each region. In the case of NCR, it shall be considered as a single unit III. The distance between the two farthest establishments/outlets supervised by a single pharmacist must not exceed fifty (50) km in distance IV. A pharmacist shall be allowed to supervise a minimum of fifteen (15) establishment/outlets

I, II

A pharmacist working in Category A establishment/outlet may be allowed to simultaneously work in Category B establishment/outlet.

True

Identify the law violated when Pharmacy X was found selling counterfeit medicines:

RA 8203

100

In RA 11223, population-based health services shall be financed by:

Department of Health

Module 2 Part 1

Module 2 Part 1

Module 1

Module 1

Module 2

Module 2

Antibiotics

Antibiotics

Module 2 Part 2

Module 2 Part 2

Module 2 (Part 2)

Module 2 (Part 2)

Module 2 Part 3

Module 2 Part 3

Module 4

Module 4

Module 4 Part 2

Module 4 Part 2

Module 4 Part 3

Module 4 Part 3

Module 2 (Part 4)

Module 2 (Part 4)

Randome Questions

Randome Questions

Module 2 (Part 5)

Module 2 (Part 5)

Module 2 (Part 6)

Module 2 (Part 6)

Module 4 Part 1

Module 4 Part 1

問題一覧

Analyze and select the basic product formulation for a tablet.

Active Ingredient, Diluent or Filler, Binder, Disintegrant, Lubricant

Select the oral dosage form, which contains one or more active ingredients dissolved in a suitable base.

Oral Solution

Which of the following statements is correct regarding oral solutions?

Oral pharmaceutical solutions are usually formulated so that the patient receives the usual dose in a conveniently administered volume, such as 5 mL (1 tsp), 10 mL, or 15 mL (1 tbsp).

Select the undesirable characteristic of a dispersed phase of a suspension:

Enhances crystal growth formation

Which of the following is considered an undesirable quality of a suspension?

Suspended particles settle rapidly

Which of the following is a disadvantage characteristic of suspension?

Formation of a compact when the particles eventually settle

Which of the following statement is true regarding suspension?

Suspensions are chemically more stable than solutions.

Select the appropriate procedure to produce aesthetically pleasing suspension:

Add an amount of flocculating agent that will bring about a sedimentation volume equal to 1

First pharmaceutical product of recombinant DNA technology:

Human insulin

Capsule shaped compressed tablet that allows the coated product to be about one third smaller than a capsule filled with an equivalent amount of powder.

Gelatin coated tablet

Classify the medical device: Pacemaker

Class III

SPF

Sun protection factor

Amphoteric surfactants:

Betaine

Select the principal category to which ethyl cellulose belong:

Tablet Binder

Classify clay, silica gel, colloids, metals, activated charcoal, activated alumina as a pharmaceutical excipient:

Adsorbent

Classify glycerin, honey, glucose syrup, egg yolk, sugar alcohols as a pharmaceutical excipient:

Humectant

The following pair are coarse dispersions

Emulsion and suspension

Antifoaming agent:

Castor Oil

Identify the components of yellow ointment:

Yellow wax, yellow petrolatum

Which of the following are used as pharmaceutical ointment bases? I. Lanolin II. Mineral Oil III. Petrolatum IV. Glycerin

I, III

I, II, IV

Compute for the volume of alcohol to be added to preserve the prescription below. Rx Active drug 5mL Other Drug solids 3 mL Glycerin 15 mL Sucrose 25 g Ethanol 95% q.s Purified water, q.s. 100mL

6.21 mL

Which of the following is correctly matched?

Liniments – Oleaginous

I, II, III

Purified Water

Which is not an ideal characteristic of a suppository base?

Remains stable in rectal fluids

Find the incorrect statement about theobroma oil:

It is a naturally occurring alkaloid.

Identify cosmetics which are regulated as a drugs:

Lip Balms, Mouthwashes, Antiperspirants, Diaper Ointments

Use of potassium diformate in veterinary medicine:

Strong Antimicrobial

Select the category of emulsifiers or stabilizers that are used primarily as thickening agents and stabilizers for oil in-water emulsions of certain lotions and ointments for external use

HMW alcohols

Method of preparing powders that consists of enclosing the powder container, which rotates and mixes the powder ingredients:

Tumbling

Preservatives interfere with microbial growth and metabolism through one or more of these mechanisms, EXCEPT________:

Reversible protein precipitation

Which sterilization method allows the sterilization of packaged finished products that are ready for shipment because sterilizing material permeates sealed plastic films and cartons?

Gas Sterilization

Identify the colorant not obtained from a biological source:

Nitroso-Dyes

Reason why granules or coarse particles is preferred over fine powders in effervescent preparations.

Decrease dissolution leading to a less violent effervescence.

Defined as the breaking of tablet edges, while the tablet leaves the press or during subsequent handling and coating operations:

Chipping

Types of suppositories: I. Urethral III. Rectal II. Vaginal IV. Oral

I, II and III

Which of the following is a suspension?

Magaldrate

Arrange the following steps of sugarcoating process: I. Color coating IV. Polishing II. Sealing V. Subcoating III. Smoothing

II-V-III-I-IV

Select the appropriate remedy for a capsule defect where the active ingredient prescribed dissolves in an acid medium:

Coat the capsules with polyvinyl acetate phthalate.

This step allows the flavor and odor of a solution to enhance:

Aging

Range of sodium ion concentration in a TPN preparation:

100 – 120 mEq

Determine the effect of overwetting to resulting granules:

Granules will be hard

Sodium bisulfite

Antioxidant

Type II

This explains the erratic motion of colloid

Brownian motion

225 g

Tablets which have a smooth, rapid disintegration when chewed or allowed to dissolve in the mouth, have a creamy base, usually of specially flavored and colored mannitol.

Chewable tablet

Constitutive property

Refractive index

Classify the following techniques to its corresponding flavoring methodology: Use of menthol to anesthetized taste buds

Physiological

Identify the forces that account for the solubility of iodine in a solution of KI:

Ion-Dipole, Ion- Induced Dipole Forces

Which of the following is the most stable form of chelates?

5- to 6-membered rings

Identify the Law/ Principles which states that when the reaction is reversible, delta S=0:

Gibbs Free Energy

Find the classification of Complexes:

Metal Complexes, Organic Complexes, Inclusion/Occlusion Compounds

Ethylenediamineteatraacetic acid is a:

Hexadentate

Identify the statement/mathematical expression, which does NOT express the First Law of Thermodynamics:

∆ E = EB + EA

Select the concept that explains the thermodynamics state of a perfect crystal at absolute zero:

3rd Law of Thermodynamics

I, II, III

I, III, IV

I, II, III

Select the viscometers which can be used for both Newtonian and Non-Newtonian system:

Cup and Bob, Cone and Plate

Select the Non-Newtonian liquids

Tobramycin, Chloramphenicol Palmitate Suspension

Analyze and select the factor that governs the degree of repulsion in systems containing dispersed particles.

Electrokinetic Potential

0.76 g

Calculate the approximate E value of boric acid. (MW 61.84, Liso 1.8)

0.5

Strongest intermolecular force

Hydrogen bond

Select the statement that characterizes association colloids:

Micelles are aggregates of molecules or ions of the substance dissolved in the dispersion medium.

Identify the property which is used to determine the molecular weight of colloids:

Light Scattering

Find the statement that is INCORRECT regarding the influence of some factors on the solubility of solids:

The configuration of a solid molecule has NO effect on its solubility.

Select the statement that BEST describes solubility of solids in liquids:

The solubility of a solid in an ideal solution depends on the temperature, melting point of the solid and molar heat of fusion.

Lyophilic colloids

Gelatin

The difference between the surface tensions of the liquid/vapor and solid/vapor and that of the solid/liquid:

Work Of Adhesion

Molecules and ions that are adsorbed at interfaces are termed as:

AOTA

Defined as the difference in potential between the actual surface and the electroneutral region of the solution:

both Nernst Potential and Electrothermodynamic Potential

The following are true about Brownian movement except:

The velocity of the particles decreases with decreasing particle size

The following are true about viscosity of colloidal dispersions except:

Spherocolloids form dispersions of relatively high viscosity

Hypertonic solution:

18 mL

– 1.6 dynes/cm

The following are true about the stability of colloids except:

NOTA

The following are true about chelates except:

When the ligand provides one group for attachment to the central ion, the chelate is called bidentate

The following are true about organic molecular complexes except:

NOTA

The following are true about drug complexes except:

NOTA

The following are true about inclusion/ occlusion compound complexes except:

NOTA

A sample of calcium oxide powder with a true density of 3.203 and weighing 131.3 g was found to have a bulk volume of 82.0 cm3 when placed in a 100 mL graduated cylinder. Calculate the porosity.

50%

Liso of non-electrolytes

1.9

Select the statement that best describes “Refilling of a Prescription”:

Dispensing the remaining balance of medicines ordered in the prescription

Violative prescription:

Only the brand name is written on the prescription, with the phrase, “No substitution”

Agency where the pharmacist must report the destruction of dangerous drugs?

PDEA

A person affixing “RPh” title on his/her name violates the:

Philippine Pharmacy Act

What are the components of the “Essential Health Benefit Package” based on the Universal Health Care Law:

Primary care, medicines, diagnostic and laboratory tests, preventive, curative, rehabilitative services

Applicable S-license for the retail of DP/s containing Table I Controlled Chemical/s:

S-1

NOTA

Magna Carta for Disabled Persons

RA 7277

Legal basis of Immunizing Pharmacist Certification

Professional Regulatory Board of Pharmacy Resolution No. 05 series of 2021

I, II

A pharmacist working in Category A establishment/outlet may be allowed to simultaneously work in Category B establishment/outlet.

True

Identify the law violated when Pharmacy X was found selling counterfeit medicines:

RA 8203

100

In RA 11223, population-based health services shall be financed by:

Department of Health