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G. Anti-Parkinson Drugs
26問 • 1年前
  • ユーザ名非公開
    • 通報

    問題一覧

  • 1

    Degeneration of dopaminergic neurons that arise in the substance nigra (misfolding of alpha-synuclein)

    Parkinson’s Disease

  • 2

    -capone drugs

    COMT Blockers

  • 3

    Precursor of Dopamine

    Levodopa

  • 4

    Conversion of Levodopa to Dopamine is via what enzyme?

    Dopa decarboxylase

  • 5

    Carbidopa is combined with Levodopa:

    blocks dopa decarboxylase peripherally, to lessen nausea and vomitting

  • 6

    Levodopa is polar

    true

  • 7

    Dopamine is polar

    true

  • 8

    Levodopa and Dopamine are polar drugs but with the help this enzyme they can enter the BBB

    L-AAT or L-Amino Acyl Transporter via active process

  • 9

    Levodopa + Carbidopa

    Potentiation

  • 10

    To lessen the “ON-OFF” phenomenon during Levodopa treatment. What drugs can be added to help this situation?

    Selegelin; MAO-B inhibitor

  • 11

    Levodopa happens to “WEAR-OFF” due to being converted to non polar and oxidase reactions. To lessen the wear-off phenomenon, what drug should be added to the treatment?

    COMT blockers (-capones)

  • 12

    Drug of choice for Parkinson’s Disease

    Levodopa

  • 13

    Drug of choice for Parkison-LIKE disease

    Biperidine / Benztropine / Trihexyphenidyl

  • 14

    INCREASED prolactin = _______ Dopamine

    DECREASE

  • 15

    Pergolide, an ergot derivatives used for parkinsonism was withdrawn from the market due to

    Cardiac Fibrosis

  • 16

    FDA-approved drugs for hyperprolactinemia (increased prolactins)

    Ergots: Bromocriptine / Cabergoline

  • 17

    Anti-viral and anti-PD

    Amantadine

  • 18

    FDA-approved drugs for restless leg syndrome (RLS)

    Non Ergots: Ropinirole / Rotigotine / Pramipexole

  • 19

    A/Es of Amantadine

    Livedo reticularis

  • 20

    Bromocriptine/ Cabergoline

    Ergot derivative dopamine agonist

  • 21

    Ropinirole / Rotigotine / Pramipexole

    Non ergot derivative dopamine agonist

  • 22

    Bromocriptine

    Ergot derivative dopamine agonist

  • 23

    Cabergoline

    Ergot derivative dopamine agonist

  • 24

    Ropinirole

    Non ergot derivative dopamine agonist

  • 25

    Rotigotine

    Non ergot derivative dopamine agonist

  • 26

    Pramipexole

    Non ergot derivative dopamine agonist

    • Module 2 Part 1

    Module 2 Part 1

    ユーザ名非公開 · 100問 · 1年前

    Module 2 Part 1

    Module 2 Part 1

    100問 • 1年前
    ユーザ名非公開

    Module 1

    Module 1

    ユーザ名非公開 · 13問 · 1年前

    Module 1

    Module 1

    13問 • 1年前
    ユーザ名非公開

    Module 2

    Module 2

    ユーザ名非公開 · 100問 · 1年前

    Module 2

    Module 2

    100問 • 1年前
    ユーザ名非公開

    Antibiotics

    Antibiotics

    ユーザ名非公開 · 10問 · 1年前

    Antibiotics

    Antibiotics

    10問 • 1年前
    ユーザ名非公開

    Module 2 Part 2

    Module 2 Part 2

    ユーザ名非公開 · 100問 · 1年前

    Module 2 Part 2

    Module 2 Part 2

    100問 • 1年前
    ユーザ名非公開

    Module 2 (Part 2)

    Module 2 (Part 2)

    ユーザ名非公開 · 100問 · 1年前

    Module 2 (Part 2)

    Module 2 (Part 2)

    100問 • 1年前
    ユーザ名非公開

    Module 2 Part 3

    Module 2 Part 3

    ユーザ名非公開 · 85問 · 1年前

    Module 2 Part 3

    Module 2 Part 3

    85問 • 1年前
    ユーザ名非公開

    Module 4

    Module 4

    ユーザ名非公開 · 100問 · 1年前

    Module 4

    Module 4

    100問 • 1年前
    ユーザ名非公開

    Module 4 Part 2

    Module 4 Part 2

    ユーザ名非公開 · 100問 · 1年前

    Module 4 Part 2

    Module 4 Part 2

    100問 • 1年前
    ユーザ名非公開

    Module 4 Part 3

    Module 4 Part 3

    ユーザ名非公開 · 60問 · 1年前

    Module 4 Part 3

    Module 4 Part 3

    60問 • 1年前
    ユーザ名非公開

    Module 2 (Part 4)

    Module 2 (Part 4)

    ユーザ名非公開 · 68問 · 1年前

    Module 2 (Part 4)

    Module 2 (Part 4)

    68問 • 1年前
    ユーザ名非公開

    Randome Questions

    Randome Questions

    ユーザ名非公開 · 13問 · 1年前

    Randome Questions

    Randome Questions

    13問 • 1年前
    ユーザ名非公開

    1

    1

    ユーザ名非公開 · 100問 · 1年前

    1

    1

    100問 • 1年前
    ユーザ名非公開

    Module 2 (Part 5)

    Module 2 (Part 5)

    ユーザ名非公開 · 100問 · 1年前

    Module 2 (Part 5)

    Module 2 (Part 5)

    100問 • 1年前
    ユーザ名非公開

    2

    2

    ユーザ名非公開 · 100問 · 1年前

    2

    2

    100問 • 1年前
    ユーザ名非公開

    Module 2 (Part 6)

    Module 2 (Part 6)

    ユーザ名非公開 · 68問 · 1年前

    Module 2 (Part 6)

    Module 2 (Part 6)

    68問 • 1年前
    ユーザ名非公開

    Module 4 Part 1

    Module 4 Part 1

    ユーザ名非公開 · 5問 · 1年前

    Module 4 Part 1

    Module 4 Part 1

    5問 • 1年前
    ユーザ名非公開

    問題一覧

  • 1

    Degeneration of dopaminergic neurons that arise in the substance nigra (misfolding of alpha-synuclein)

    Parkinson’s Disease

  • 2

    -capone drugs

    COMT Blockers

  • 3

    Precursor of Dopamine

    Levodopa

  • 4

    Conversion of Levodopa to Dopamine is via what enzyme?

    Dopa decarboxylase

  • 5

    Carbidopa is combined with Levodopa:

    blocks dopa decarboxylase peripherally, to lessen nausea and vomitting

  • 6

    Levodopa is polar

    true

  • 7

    Dopamine is polar

    true

  • 8

    Levodopa and Dopamine are polar drugs but with the help this enzyme they can enter the BBB

    L-AAT or L-Amino Acyl Transporter via active process

  • 9

    Levodopa + Carbidopa

    Potentiation

  • 10

    To lessen the “ON-OFF” phenomenon during Levodopa treatment. What drugs can be added to help this situation?

    Selegelin; MAO-B inhibitor

  • 11

    Levodopa happens to “WEAR-OFF” due to being converted to non polar and oxidase reactions. To lessen the wear-off phenomenon, what drug should be added to the treatment?

    COMT blockers (-capones)

  • 12

    Drug of choice for Parkinson’s Disease

    Levodopa

  • 13

    Drug of choice for Parkison-LIKE disease

    Biperidine / Benztropine / Trihexyphenidyl

  • 14

    INCREASED prolactin = _______ Dopamine

    DECREASE

  • 15

    Pergolide, an ergot derivatives used for parkinsonism was withdrawn from the market due to

    Cardiac Fibrosis

  • 16

    FDA-approved drugs for hyperprolactinemia (increased prolactins)

    Ergots: Bromocriptine / Cabergoline

  • 17

    Anti-viral and anti-PD

    Amantadine

  • 18

    FDA-approved drugs for restless leg syndrome (RLS)

    Non Ergots: Ropinirole / Rotigotine / Pramipexole

  • 19

    A/Es of Amantadine

    Livedo reticularis

  • 20

    Bromocriptine/ Cabergoline

    Ergot derivative dopamine agonist

  • 21

    Ropinirole / Rotigotine / Pramipexole

    Non ergot derivative dopamine agonist

  • 22

    Bromocriptine

    Ergot derivative dopamine agonist

  • 23

    Cabergoline

    Ergot derivative dopamine agonist

  • 24

    Ropinirole

    Non ergot derivative dopamine agonist

  • 25

    Rotigotine

    Non ergot derivative dopamine agonist

  • 26

    Pramipexole

    Non ergot derivative dopamine agonist