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Routes of Administration
79問 • 1年前
  • ユーザ名非公開
    • 通報

    問題一覧

  • 1

    Also known as presystemic metabolism

    First Pass Effect

  • 2

    High First Pass Effect: _____ Bioavailability

    Decreased

  • 3

    Must be swallowed and has COMPLETE first-pass effect

    Oral Route

  • 4

    Provides systemic effect

    Oral Route

  • 5

    Drug is inserted in the rectum

    Rectal Route

  • 6

    May give local or systemic effect Buccal route

    Rectal Route

  • 7

    Can partially bypass the first-pass effect

    Rectal Route

  • 8

    Placed BETWEEN gums and inner lining of the cheek

    Buccal Route

  • 9

    Placed under the tongue

    Sublingual route

  • 10

    Available dosage form for Nitroglycerin

    Sublingual route

  • 11

    ENTERAL routes that CAN COMPLETELY BYPASS FIRST PASS EFFECT

    Sublingual route, Buccal Route

  • 12

    Emergency route

    IV Push

  • 13

    Non Emergency Route (More that 30 minutes)

    IV Infusion

  • 14

    Both emergency and non emergency route (1-30 minutes)

    IV Bolus

  • 15

    Which is slower among the two

    Subcutaneous

  • 16

    Injected into the muscle

    Intramuscular

  • 17

    90 degrees angle

    Intramuscular

  • 18

    Injected into the veins

    Intravenous

  • 19

    25 degrees angle

    Intravenous

  • 20

    100% Bioavailability or Absolute availability

    Intravenous

  • 21

    TB testing route

    Intradermal

  • 22

    Allergy testing route

    Intradermal

  • 23

    Injected into the dermis

    Intradermal

  • 24

    Injected into the corium

    Intradermal

  • 25

    10-15 degree angle

    Intradermal

  • 26

    Carbonic Anhydrase Inhibitor that is DIURETIC also a treatment for GLAUCOMA

    Acetazolamide

  • 27

    Injected under the skin

    Subcutaneous

  • 28

    25 degrees angle

    Subcutaneous

  • 29

    Drug given via subcutaneous route

    Heparin

  • 30

    Drug given via subcutaneous route

    Insulin

  • 31

    Injected into the spinal canal

    Intrathecal

  • 32

    Injected into the subarachnoid spaces

    Intrathecal

  • 33

    20 degrees angle

    Intrathecal

  • 34

    Methotrexate

    Intrathecal

  • 35

    Cytarabine

    Intrathecal

  • 36

    Hydrocortisone

    Intrathecal

  • 37

    Morphine

    Intrathecal

  • 38

    Morphine

    Intrathecal

  • 39

    Vinca alkaloids such as Vincristine when given intrathecally:

    Fatal

  • 40

    Injected inside the joint cavity

    Intra-articular

  • 41

    45 degree angle

    Intra-articular

  • 42

    Route of Glucocorticoids for Osteoarthritis

    Intra-articular

  • 43

    Route of Hyarulonic acid for Osteoarthritis

    Intra-articular

  • 44

    Identify the ROA used in the graph This is given via IV

    IV Bolus

  • 45

    Identify the route of administration used in the graph Given via IV

    IV Infusion

  • 46

    Identify the route of administration used in the graph Given via orally

    Extended release

  • 47

    Identify the route of administration used in the graph Given via orally

    Immediate release

  • 48

    Quick release when taken orally

    Immediate release

  • 49

    Steady state drug concentration

    Extended release

  • 50

    Allows precise control of PLASMA drug concentration

    IV Infusion

  • 51

    Rapid injection of medication needed to achieve immediate effect

    IV Bolus

  • 52

    Peak concentration is obtained Immediately after the dose is given

    IV Bolus

  • 53

    What is collor green in the graph

    Extended released

  • 54

    What is collor red in the graph

    Immediate released

  • 55

    What is collor blue in the graph

    Delayed released

  • 56

    Drug A is extended release and Drug B is given delayed release but has the same brand

    Pharmaceutical Alternative

  • 57

    What ROA are the zigzags, red and black

    Multiple IV Bolus

  • 58

    What ROA is the curve line color black?

    IV Infusion

  • 59

    Cmax

    Peak

  • 60

    Cmin

    Trough

  • 61

    Time the trough level needed to reach the MEC

    8

  • 62

    Time the trough level needed to reach the CSS or Concentration of Steady State

    16

  • 63

    What would most likely be the reason for the drug’s increasing plasma concentration towards reaching the therapeutic range?

    Decreasing clearance of the drug thru time

  • 64

    Increasing Plasma Concentration = Increased half life = _______ Drug clearance

    Decreasing

  • 65

    Administered at the SITE where the pharmacological response is desired

    Local Route

  • 66

    Have MINIMAL absorption to the SYSTEMIC circulation

    Local Route

  • 67

    Salbutamol for Asthma

    Local Route

  • 68

    Topical steroids for Eczema

    Local Route

  • 69

    ICS drugs for Allrgic rhinitis

    Local Route

  • 70

    The drug administered reaches the blood stream and produce systemic effect

    Systemic Route

  • 71

    Oral Amoxicillin

    Systemic Effect

  • 72

    Intravenous and Intramuscular

    Systemic Effect

  • 73

    Transdermal patch

    Systemic Effect

  • 74

    Rectal

    Both

  • 75

    Bronchodilators

    Local effects

  • 76

    GENERAL anesthesia

    Systemic Effect

  • 77

    Which of the following refers to the form of parenteral administration that involves injecting drugs such as methotrexate to the spinal cord?

    Intrathecal

  • 78

    The peak concentration for an intravenous bolus dose would be obtained ____.

    Immediately after the dose is given

  • 79

    Which are TRUE regarding local effect of drugs? I. Drug is administered at the site where the pharmacological response is desired. II. Drug preparations intended to produce local effects have minimal absorption to the systemic circulation. III. Anti-asthma drugs administered via inhalational route produce local effects.

    I, II and III

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    問題一覧

  • 1

    Also known as presystemic metabolism

    First Pass Effect

  • 2

    High First Pass Effect: _____ Bioavailability

    Decreased

  • 3

    Must be swallowed and has COMPLETE first-pass effect

    Oral Route

  • 4

    Provides systemic effect

    Oral Route

  • 5

    Drug is inserted in the rectum

    Rectal Route

  • 6

    May give local or systemic effect Buccal route

    Rectal Route

  • 7

    Can partially bypass the first-pass effect

    Rectal Route

  • 8

    Placed BETWEEN gums and inner lining of the cheek

    Buccal Route

  • 9

    Placed under the tongue

    Sublingual route

  • 10

    Available dosage form for Nitroglycerin

    Sublingual route

  • 11

    ENTERAL routes that CAN COMPLETELY BYPASS FIRST PASS EFFECT

    Sublingual route, Buccal Route

  • 12

    Emergency route

    IV Push

  • 13

    Non Emergency Route (More that 30 minutes)

    IV Infusion

  • 14

    Both emergency and non emergency route (1-30 minutes)

    IV Bolus

  • 15

    Which is slower among the two

    Subcutaneous

  • 16

    Injected into the muscle

    Intramuscular

  • 17

    90 degrees angle

    Intramuscular

  • 18

    Injected into the veins

    Intravenous

  • 19

    25 degrees angle

    Intravenous

  • 20

    100% Bioavailability or Absolute availability

    Intravenous

  • 21

    TB testing route

    Intradermal

  • 22

    Allergy testing route

    Intradermal

  • 23

    Injected into the dermis

    Intradermal

  • 24

    Injected into the corium

    Intradermal

  • 25

    10-15 degree angle

    Intradermal

  • 26

    Carbonic Anhydrase Inhibitor that is DIURETIC also a treatment for GLAUCOMA

    Acetazolamide

  • 27

    Injected under the skin

    Subcutaneous

  • 28

    25 degrees angle

    Subcutaneous

  • 29

    Drug given via subcutaneous route

    Heparin

  • 30

    Drug given via subcutaneous route

    Insulin

  • 31

    Injected into the spinal canal

    Intrathecal

  • 32

    Injected into the subarachnoid spaces

    Intrathecal

  • 33

    20 degrees angle

    Intrathecal

  • 34

    Methotrexate

    Intrathecal

  • 35

    Cytarabine

    Intrathecal

  • 36

    Hydrocortisone

    Intrathecal

  • 37

    Morphine

    Intrathecal

  • 38

    Morphine

    Intrathecal

  • 39

    Vinca alkaloids such as Vincristine when given intrathecally:

    Fatal

  • 40

    Injected inside the joint cavity

    Intra-articular

  • 41

    45 degree angle

    Intra-articular

  • 42

    Route of Glucocorticoids for Osteoarthritis

    Intra-articular

  • 43

    Route of Hyarulonic acid for Osteoarthritis

    Intra-articular

  • 44

    Identify the ROA used in the graph This is given via IV

    IV Bolus

  • 45

    Identify the route of administration used in the graph Given via IV

    IV Infusion

  • 46

    Identify the route of administration used in the graph Given via orally

    Extended release

  • 47

    Identify the route of administration used in the graph Given via orally

    Immediate release

  • 48

    Quick release when taken orally

    Immediate release

  • 49

    Steady state drug concentration

    Extended release

  • 50

    Allows precise control of PLASMA drug concentration

    IV Infusion

  • 51

    Rapid injection of medication needed to achieve immediate effect

    IV Bolus

  • 52

    Peak concentration is obtained Immediately after the dose is given

    IV Bolus

  • 53

    What is collor green in the graph

    Extended released

  • 54

    What is collor red in the graph

    Immediate released

  • 55

    What is collor blue in the graph

    Delayed released

  • 56

    Drug A is extended release and Drug B is given delayed release but has the same brand

    Pharmaceutical Alternative

  • 57

    What ROA are the zigzags, red and black

    Multiple IV Bolus

  • 58

    What ROA is the curve line color black?

    IV Infusion

  • 59

    Cmax

    Peak

  • 60

    Cmin

    Trough

  • 61

    Time the trough level needed to reach the MEC

    8

  • 62

    Time the trough level needed to reach the CSS or Concentration of Steady State

    16

  • 63

    What would most likely be the reason for the drug’s increasing plasma concentration towards reaching the therapeutic range?

    Decreasing clearance of the drug thru time

  • 64

    Increasing Plasma Concentration = Increased half life = _______ Drug clearance

    Decreasing

  • 65

    Administered at the SITE where the pharmacological response is desired

    Local Route

  • 66

    Have MINIMAL absorption to the SYSTEMIC circulation

    Local Route

  • 67

    Salbutamol for Asthma

    Local Route

  • 68

    Topical steroids for Eczema

    Local Route

  • 69

    ICS drugs for Allrgic rhinitis

    Local Route

  • 70

    The drug administered reaches the blood stream and produce systemic effect

    Systemic Route

  • 71

    Oral Amoxicillin

    Systemic Effect

  • 72

    Intravenous and Intramuscular

    Systemic Effect

  • 73

    Transdermal patch

    Systemic Effect

  • 74

    Rectal

    Both

  • 75

    Bronchodilators

    Local effects

  • 76

    GENERAL anesthesia

    Systemic Effect

  • 77

    Which of the following refers to the form of parenteral administration that involves injecting drugs such as methotrexate to the spinal cord?

    Intrathecal

  • 78

    The peak concentration for an intravenous bolus dose would be obtained ____.

    Immediately after the dose is given

  • 79

    Which are TRUE regarding local effect of drugs? I. Drug is administered at the site where the pharmacological response is desired. II. Drug preparations intended to produce local effects have minimal absorption to the systemic circulation. III. Anti-asthma drugs administered via inhalational route produce local effects.

    I, II and III