Routes of Administration

79問 • 1年前

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通報

問題一覧

Also known as presystemic metabolism

First Pass Effect

High First Pass Effect: _____ Bioavailability

Decreased

Must be swallowed and has COMPLETE first-pass effect

Oral Route

Provides systemic effect

Oral Route

Drug is inserted in the rectum

Rectal Route

May give local or systemic effect Buccal route

Rectal Route

Can partially bypass the first-pass effect

Rectal Route

Placed BETWEEN gums and inner lining of the cheek

Buccal Route

Placed under the tongue

Sublingual route

Available dosage form for Nitroglycerin

Sublingual route

ENTERAL routes that CAN COMPLETELY BYPASS FIRST PASS EFFECT

Sublingual route, Buccal Route

Emergency route

IV Push

Non Emergency Route (More that 30 minutes)

IV Infusion

Both emergency and non emergency route (1-30 minutes)

IV Bolus

Which is slower among the two

Subcutaneous

Injected into the muscle

Intramuscular

90 degrees angle

Intramuscular

Injected into the veins

Intravenous

25 degrees angle

Intravenous

100% Bioavailability or Absolute availability

Intravenous

TB testing route

Intradermal

Allergy testing route

Intradermal

Injected into the dermis

Intradermal

Injected into the corium

Intradermal

10-15 degree angle

Intradermal

Carbonic Anhydrase Inhibitor that is DIURETIC also a treatment for GLAUCOMA

Acetazolamide

Injected under the skin

Subcutaneous

25 degrees angle

Subcutaneous

Drug given via subcutaneous route

Heparin

Drug given via subcutaneous route

Insulin

Injected into the spinal canal

Intrathecal

Injected into the subarachnoid spaces

Intrathecal

20 degrees angle

Intrathecal

Methotrexate

Intrathecal

Cytarabine

Intrathecal

Hydrocortisone

Intrathecal

Morphine

Intrathecal

Morphine

Intrathecal

Vinca alkaloids such as Vincristine when given intrathecally:

Fatal

Injected inside the joint cavity

Intra-articular

45 degree angle

Intra-articular

Route of Glucocorticoids for Osteoarthritis

Intra-articular

Route of Hyarulonic acid for Osteoarthritis

Intra-articular

Identify the ROA used in the graph This is given via IV

IV Bolus

Identify the route of administration used in the graph Given via IV

IV Infusion

Identify the route of administration used in the graph Given via orally

Extended release

Identify the route of administration used in the graph Given via orally

Immediate release

Quick release when taken orally

Immediate release

Steady state drug concentration

Extended release

Allows precise control of PLASMA drug concentration

IV Infusion

Rapid injection of medication needed to achieve immediate effect

IV Bolus

Peak concentration is obtained Immediately after the dose is given

IV Bolus

What is collor green in the graph

Extended released

What is collor red in the graph

Immediate released

What is collor blue in the graph

Delayed released

Drug A is extended release and Drug B is given delayed release but has the same brand

Pharmaceutical Alternative

What ROA are the zigzags, red and black

Multiple IV Bolus

What ROA is the curve line color black?

IV Infusion

Cmax

Peak

Cmin

Trough

Time the trough level needed to reach the MEC

Time the trough level needed to reach the CSS or Concentration of Steady State

What would most likely be the reason for the drug’s increasing plasma concentration towards reaching the therapeutic range?

Decreasing clearance of the drug thru time

Increasing Plasma Concentration = Increased half life = _______ Drug clearance

Decreasing

Administered at the SITE where the pharmacological response is desired

Local Route

Have MINIMAL absorption to the SYSTEMIC circulation

Local Route

Salbutamol for Asthma

Local Route

Topical steroids for Eczema

Local Route

ICS drugs for Allrgic rhinitis

Local Route

The drug administered reaches the blood stream and produce systemic effect

Systemic Route

Oral Amoxicillin

Systemic Effect

Intravenous and Intramuscular

Systemic Effect

Transdermal patch

Systemic Effect

Rectal

Both

Bronchodilators

Local effects

GENERAL anesthesia

Systemic Effect

Which of the following refers to the form of parenteral administration that involves injecting drugs such as methotrexate to the spinal cord?

Intrathecal

The peak concentration for an intravenous bolus dose would be obtained ____.

Immediately after the dose is given

Which are TRUE regarding local effect of drugs? I. Drug is administered at the site where the pharmacological response is desired. II. Drug preparations intended to produce local effects have minimal absorption to the systemic circulation. III. Anti-asthma drugs administered via inhalational route produce local effects.

I, II and III

Module 2 Part 1

Module 2 Part 1

Module 1

Module 1

Module 2

Module 2

Antibiotics

Antibiotics

Module 2 Part 2

Module 2 Part 2

Module 2 (Part 2)

Module 2 (Part 2)

Module 2 Part 3

Module 2 Part 3

Module 4

Module 4

Module 4 Part 2

Module 4 Part 2

Module 4 Part 3

Module 4 Part 3

Module 2 (Part 4)

Module 2 (Part 4)

Randome Questions

Randome Questions

Module 2 (Part 5)

Module 2 (Part 5)

Module 2 (Part 6)

Module 2 (Part 6)

Module 4 Part 1

Module 4 Part 1

BCS

BCS

Pharmacokinetics

Pharmacokinetics

Enzyme Inducers and Enzyme Inhibitors

ユーザ名非公開 · 25問 · 1年前

Enzyme Inducers and Enzyme Inhibitors

25問 • 1年前

ユーザ名非公開

Metabolism and Excretion

ユーザ名非公開 · 31問 · 1年前

Metabolism and Excretion

PHARMACODYNAMICS

PHARMACODYNAMICS

Ramdom

Ramdom

A. Parasympathetic (Cholinergic) Drugs

ユーザ名非公開 · 43問 · 1年前

A. Parasympathetic (Cholinergic) Drugs

Module 1

Module 1

Module 1

Module 1

Module 2

Module 2

Module 3

Module 3

Module 2

Module 2

Module 3

Module 3

Module 3 Rationales

Module 3 Rationales

Terms

Terms

Module 3 Rationales

Module 3 Rationales

Excipients

Excipients

Module 4

Module 4

Flavors,Sweeteners, and Colors

ユーザ名非公開 · 17問 · 1年前

Flavors,Sweeteners, and Colors

Module 5

Module 5

Anti Glaucoma

Anti Glaucoma

B. Parasympathetic (Cholinergic) Blockers — Anti Cholinergic Agents

ユーザ名非公開 · 20問 · 1年前

B. Parasympathetic (Cholinergic) Blockers — Anti Cholinergic Agents

20問 • 1年前

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C. Sympathetic (Adrenergic) Drugs

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C. Sympathetic (Adrenergic) Drugs

80問 • 1年前

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D. Sympathetic (Adrenergic) BLOCKERS

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D. Sympathetic (Adrenergic) BLOCKERS

15問 • 1年前

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E. Nicotinic Receptor Blockers

ユーザ名非公開 · 30問 · 1年前

E. Nicotinic Receptor Blockers

30問 • 1年前

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F. Central Muscle Relaxants (or Spasmolytic agents)

ユーザ名非公開 · 19問 · 1年前

F. Central Muscle Relaxants (or Spasmolytic agents)

Rationale Quiz 1.0

Rationale Quiz 1.0

A. Anxiolytic Agents

A. Anxiolytic Agents

B.1 Drugs for Depression

ユーザ名非公開 · 29問 · 1年前

B.1 Drugs for Depression

29問 • 1年前

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B.2 Drugs for Mania / Bipolar Disorder

ユーザ名非公開 · 15問 · 1年前

B.2 Drugs for Mania / Bipolar Disorder

15問 • 1年前

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C. Drugs for Psychoses - Typical and Atypical Antipsychotics

ユーザ名非公開 · 44問 · 1年前

C. Drugs for Psychoses - Typical and Atypical Antipsychotics

44問 • 1年前

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D. Drugs for Seizure Disorders

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D. Drugs for Seizure Disorders

36問 • 1年前

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E. General Anesthetics

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E. General Anesthetics

32問 • 1年前

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G. Anti-Parkinson Drugs

ユーザ名非公開 · 26問 · 1年前

G. Anti-Parkinson Drugs

26問 • 1年前

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H. Drugs for Alzheimer's Disease

ユーザ名非公開 · 6問 · 1年前

H. Drugs for Alzheimer's Disease

Rationale Quiz 2

Rationale Quiz 2

1. Diuretics

1. Diuretics

2. Angiotensin Blockers

ユーザ名非公開 · 12問 · 1年前

2. Angiotensin Blockers

12問 • 1年前

ユーザ名非公開

3 and 4. CCBs: Non-dihydropyridines and Vasodilators

ユーザ名非公開 · 20問 · 1年前

3 and 4. CCBs: Non-dihydropyridines and Vasodilators

Module 2

Module 2

Pharmacodynamics

Pharmacodynamics

Drug Classes

Drug Classes

MOA

MOA

5. Sympatholytics

5. Sympatholytics

B. Drugs for Heart Failure

ユーザ名非公開 · 6問 · 1年前

B. Drugs for Heart Failure

6問 • 1年前

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C. Drugs for Arrhythmia

ユーザ名非公開 · 36問 · 1年前

C. Drugs for Arrhythmia

36問 • 1年前

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D. Drugs for Hyperlipidemia

ユーザ名非公開 · 11問 · 1年前

D. Drugs for Hyperlipidemia

E. Angina Pectoris

E. Angina Pectoris

F. Thrombotic Disorders

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F. Thrombotic Disorders

Antidotes

Antidotes

Deficiencies

Deficiencies

A. Growth Hormones

A. Growth Hormones

B. Adrenal Steroids

B. Adrenal Steroids

C. GnRH, FSH & LH & Sex Hormones

ユーザ名非公開 · 45問 · 1年前

C. GnRH, FSH & LH & Sex Hormones

D. Thyroid Hormones

D. Thyroid Hormones

E. Diabetes Mellitus

E. Diabetes Mellitus

F. Drugs for osteoporosis

ユーザ名非公開 · 21問 · 1年前

F. Drugs for osteoporosis

Rationale Quiz

Rationale Quiz

A. Asthma

A. Asthma

B. Allergic Rhinitis

B. Allergic Rhinitis

問題一覧

Also known as presystemic metabolism

First Pass Effect

High First Pass Effect: _____ Bioavailability

Decreased

Must be swallowed and has COMPLETE first-pass effect

Oral Route

Provides systemic effect

Oral Route

Drug is inserted in the rectum

Rectal Route

May give local or systemic effect Buccal route

Rectal Route

Can partially bypass the first-pass effect

Rectal Route

Placed BETWEEN gums and inner lining of the cheek

Buccal Route

Placed under the tongue

Sublingual route

Available dosage form for Nitroglycerin

Sublingual route

ENTERAL routes that CAN COMPLETELY BYPASS FIRST PASS EFFECT

Sublingual route, Buccal Route

Emergency route

IV Push

Non Emergency Route (More that 30 minutes)

IV Infusion

Both emergency and non emergency route (1-30 minutes)

IV Bolus

Which is slower among the two

Subcutaneous

Injected into the muscle

Intramuscular

90 degrees angle

Intramuscular

Injected into the veins

Intravenous

25 degrees angle

Intravenous

100% Bioavailability or Absolute availability

Intravenous

TB testing route

Intradermal

Allergy testing route

Intradermal

Injected into the dermis

Intradermal

Injected into the corium

Intradermal

10-15 degree angle

Intradermal

Carbonic Anhydrase Inhibitor that is DIURETIC also a treatment for GLAUCOMA

Acetazolamide

Injected under the skin

Subcutaneous

25 degrees angle

Subcutaneous

Drug given via subcutaneous route

Heparin

Drug given via subcutaneous route

Insulin

Injected into the spinal canal

Intrathecal

Injected into the subarachnoid spaces

Intrathecal

20 degrees angle

Intrathecal

Methotrexate

Intrathecal

Cytarabine

Intrathecal

Hydrocortisone

Intrathecal

Morphine

Intrathecal

Morphine

Intrathecal

Vinca alkaloids such as Vincristine when given intrathecally:

Fatal

Injected inside the joint cavity

Intra-articular

45 degree angle

Intra-articular

Route of Glucocorticoids for Osteoarthritis

Intra-articular

Route of Hyarulonic acid for Osteoarthritis

Intra-articular

Identify the ROA used in the graph This is given via IV

IV Bolus

Identify the route of administration used in the graph Given via IV

IV Infusion

Identify the route of administration used in the graph Given via orally

Extended release

Identify the route of administration used in the graph Given via orally

Immediate release

Quick release when taken orally

Immediate release

Steady state drug concentration

Extended release

Allows precise control of PLASMA drug concentration

IV Infusion

Rapid injection of medication needed to achieve immediate effect

IV Bolus

Peak concentration is obtained Immediately after the dose is given

IV Bolus

What is collor green in the graph

Extended released

What is collor red in the graph

Immediate released

What is collor blue in the graph

Delayed released

Drug A is extended release and Drug B is given delayed release but has the same brand

Pharmaceutical Alternative

What ROA are the zigzags, red and black

Multiple IV Bolus

What ROA is the curve line color black?

IV Infusion

Cmax

Peak

Cmin

Trough

Time the trough level needed to reach the MEC

Time the trough level needed to reach the CSS or Concentration of Steady State

What would most likely be the reason for the drug’s increasing plasma concentration towards reaching the therapeutic range?

Decreasing clearance of the drug thru time

Increasing Plasma Concentration = Increased half life = _______ Drug clearance

Decreasing

Administered at the SITE where the pharmacological response is desired

Local Route

Have MINIMAL absorption to the SYSTEMIC circulation

Local Route

Salbutamol for Asthma

Local Route

Topical steroids for Eczema

Local Route

ICS drugs for Allrgic rhinitis

Local Route

The drug administered reaches the blood stream and produce systemic effect

Systemic Route

Oral Amoxicillin

Systemic Effect

Intravenous and Intramuscular

Systemic Effect

Transdermal patch

Systemic Effect

Rectal

Both

Bronchodilators

Local effects

GENERAL anesthesia

Systemic Effect

Which of the following refers to the form of parenteral administration that involves injecting drugs such as methotrexate to the spinal cord?

Intrathecal

The peak concentration for an intravenous bolus dose would be obtained ____.

Immediately after the dose is given

I, II and III