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100問 • 1年前
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    問題一覧

  • 1

    The intensity of the pharmacological action of the drug is most dependent on ____________.

    Concentration of the drug at the receptor site.

  • 2

    True for an antagonist: I. No affinity II. No intrinsic activity III. Initiates biological response

    II

  • 3

    When a drug has narrow therapeutic index, it indicates that a drug is

    Less safe

  • 4

    If 1 mg of lorazepam produces the same anxiolytic response as 10 mg of diazepam, which is correct?

    Lorazepam is more potent than diazepam.

  • 5

    In the presence of picrotoxin, diazepam is less efficacious at causing sedation, regardless of the dose. Picrotoxin has no sedative effect, even at the highest dose. Which of the following is correct regarding these agents?

    Picrotoxin is a non competitive antagonist.

  • 6

    Which of the following describes the action of Protamine against Heparin?

    Chemical antagonism

  • 7

    True regarding active transport:

    AOTA

  • 8

    All of the following statements regarding drug transport are true except

    High molecular weight drugs diffuse across cell membrane more easily than low molecular weight drugs.

  • 9

    Administration of a sulfonamide antibiotic may displace bilirubin from binding sites on which of the following substances, leading to passage of bilirubin into the brain and the development of kernicterus?

    albumin

  • 10

    All of the following statements about plasma protein binding of a drug are true except which one?

    Drugs that are highly bound to plasma proteins generally have a greater VD compared with drugs that are highly bound to tissue proteins.

  • 11

    Food delays gastric emptying time. What effect does this have on absorption of orally administered drugs?

    Decreased absorption

  • 12

    According to Biopharmaceutics Classification System (BCS), a drug with high solubility and low permeability belongs to:

    Class 3

  • 13

    Pharmaceutical equivalent drug products must have the same ____________. I. Therapeutically active drug ingredients II. Salts or ester III. Dosage form and strength

    I, II & III

  • 14

    Drug metabolism happens in most cases, to convert the drug to a compound that is ____________. I. More polar II. More non-polar III. More lipid-soluble IV. More water-soluble

    I & IV

  • 15

    Pathway of drug biotransformation where it introduces or exposes a functional group on the drug molecules

    Phase 1

  • 16

    Isoniazid undergoes what type of conjugation reaction?

    Acetylation

  • 17

    Chloramphenicol is considered to be toxic in infants. This is due to tissue accumulation of unchanged chloramphenicol, resulting from an immature metabolic pathway. Which of the following enzymes would most likely be deficient?

    Glucuronosyltransferase

  • 18

    Inducers: I. Increase drug metabolizing enzymes II. Decrease drug metabolizing enzymes III. Increase plasma drug concentration of another drug IV. Decrease plasma drug concentration of another drug

    I & IV

  • 19

    Human milk is more acidic than plasma. Which of the following statements are true given this condition? I. Weak acid may diffuse into the breast milk and ionize. II. Weak acid may diffuse into the breast milk and remain unionized. III. Weak base may diffuse into the breast milk and ionize. IV. Weak base may diffuse into the breast milk and remain unionized

    II & III

  • 20

    The excretion of a weakly acidic drug is generally more rapid in alkaline urine than in acidic urine. This process occurs because I. A weak acid in alkaline media will exist primarily in its ionized form, which cannot be reabsorbed easily. II. A weak acid in alkaline media will exist in its lipophilic form, which cannot be reabsorbed easily. III. All drugs are excreted more rapidly in an alkaline urine.

    I only

  • 21

    The renal clearance of inulin is used as a measurement of

    GFR

  • 22

    A drug that will prevent the storage of cholinergic transmitter in vesicles thereby depleting the transmitter at the synapse.

    Vesamicol

  • 23

    This drug inhibits the release of acetylcholine. Has cosmetic use and is particularly important in treating strabismus and blepharospasms.

    Botox

  • 24

    The only adrenoceptor that is presynaptic in location

    Alpha 2

  • 25

    Ritodrine works as a tocolytic by activating this receptor

    Beta 2

  • 26

    Which of the following ingredients of a cough and cold preparation is classified as a decongestant.

    Phenylephrine

  • 27

    All of the following adverse effects are manifestations of cholinergic agonists except

    Xerostomia

  • 28

    An indirect acting cholinomimetic used in the diagnosis of myasthenia gravis.

    Edrophonium

  • 29

    The following are signs and symptoms of Organophosphate poisoning except

    Tachycardia

  • 30

    Toxicity of atropine can be managed by giving

    Physostigmine

  • 31

    Most of the drugs used in the treatment of Alzheimer’s disease are designed to produce ____________ effects.

    Cholinergic

  • 32

    An endogenous catecholamine that is used as the DOC for septic shock

    NE

  • 33

    Amphetamine exemplifies the pharmacologic mechanism of

    facilitation of transmitter release

  • 34

    A 58-year-old white male who has a history of essential hypertension and bronchial asthma has recently been diagnosed with prostatic hypertrophy. His medication history includes the following drugs: I. Propranolol IV. Finasteride II. Ipratropium V. Prazosin III. Metaproterenol Which agent would be most likely to cause postural hypotension?

    V

  • 35

    This dopamine 1 agonist can be used for hypertensive emergency due to its vasodilating effect

    Fenoldopam

  • 36

    Blood pressure of 120/90 mm Hg falls under what category of hypertension?

    Stage 1

  • 37

    James Dean went to the barangay clinic because he had been complaining of severe headaches, dizziness, and chest pain. Upon examination, the doctor diagnosed him with hypertension of unknown cause. Patients in whom no specific cause of hypertension can be found are said to have:

    Primary HTN

  • 38

    The following can be given to patients with hypertension and asthma except

    Nadolol

  • 39

    The pharmacologic profile of carvedilol is most similar to that of

    Labetalol

  • 40

    Norvasc ®

    Amlodipine

  • 41

    Prodrugs except

    Captopril

  • 42

    Angiotensin receptor antagonists or blockers (ARBs) are less likely to cause angioedema and cough than the angiotensin-converting enzyme inhibitors (ACEI) because

    ARBs do not inhibit the breakdown of bradykinin.

  • 43

    The following can give rise to birth defects except

    Methyldopa

  • 44

    Which of the following antihypertensives does not act at autonomic receptors?

    Hydralazine

  • 45

    Class of diuretics that commonly causes ototoxicity.

    Loop diuretics

  • 46

    Which of the following diuretics is contraindicated in patients with increased calcium levels in the blood?

    Chlorthalidone

  • 47

    It interferes with collecting tubular aldosterone-mediated sodium–potassium exchange and may cause hyperkalemia, gynecomastia, and menstrual irregularities.

    Spironolactone

  • 48

    The principal site of action of this drug is on the thick ascending limb of the loop of Henle. It is useful in treating pulmonary edema.

    Furosemide

  • 49

    Visual disturbances (yellow or green vision), confusion, anorexia, vomiting, atrioventricular (AV) block, and ventricular tachycardia are adverse effects of

    Cardiac glycosides

  • 50

    Antidote for Digoxin toxicity.

    AOTA

  • 51

    Which of the following pairings of an unwanted effect and the causative drug are true? I. Headache with Nitrates II. Cough with Irbesartan III. Lupus-like syndrome with Hydralazine

    I & III

  • 52

    Odd one out

    Enoxaparin

  • 53

    Close monitoring of anticoagulants is essential to prevent life-threatening effects such as bleeding. What should be monitored during Heparin therapy?

    aPTT

  • 54

    Prototype drug that prevents thromboxane A2 formation by inhibiting COX-1.

    Aspirin

  • 55

    All of the following agents have actions on blood platelets to modify clot formation except

    Dabigatran

  • 56

    Drug of choice for hypercholesterolemia

    HMG-CoA Reductase inhibitors

  • 57

    Much of the reduction in circulating LDL during treatment with simvastatin may be due to

    upregulation of HMG-CoA reductase

  • 58

    The following can be taken any time of the day except

    Pravastatin

  • 59

    Tyramine-containing food may cause dangerous hypertension in patients on this agent. I. Tranylcypromine IV. Fluoxetine II. Imipramine V. Phenelzine III. Buspirone

    l & V

  • 60

    A 38-year-old man has a history of affective disorders, including schizophrenia, depression, obsessive–compulsive disorder, and situational anxiety. His current medication profile includes the following drugs: I. Clozapine III. Buspirone II. Fluoxetine IV. Amoxapine Which agent is most likely being used to treat depression and obsessive– compulsive disorder?

    II

  • 61

    The following selectively block serotonin transporter except

    Doxepine

  • 62

    Which of the following agents is not used to treat anxiety?

    Thioridazine

  • 63

    The primary concern with opioid use during surgical procedures and overdose is the potential for significant respiratory and CNS depression leading to coma. This can be managed by the administration of opioid antagonists such as nalbuphine.

    First statement is correct

  • 64

    Which of the following drug combinations could work cooperatively to enhance a clinical anti-parkinsonian response?

    Levodopa and carbidopa

  • 65

    Which of the following statements are true regarding the similarities of Phenytoin and Phenobarbital? I. They have anti-epileptic effects II. They are enzyme inhibitors III. They both have low therapeutic indices

    I & III

  • 66

    Certain drugs are sometimes incorporated into local anesthetic solutions to prolong their activity and reduce their systemic toxicity. These drugs include I. Dobutamine II. Phenoxybenzamine III. Epinephrine

    III only

  • 67

    Which element is used in the management of Rheumatoid Arthritis?

    Gold

  • 68

    Cold intolerance and slowing down of metabolism are symptoms of?

    Hypothyroidism

  • 69

    All of the following can be used to treat hypothyroidism except

    Methimazole

  • 70

    The preferred drug given in the first trimester of pregnant patients with hyperthyroidism

    Propylthiouracil (PTU)

  • 71

    Which of the following preparations is a peakless insulin?

    Insulin Glargine

  • 72

    Which of the following insulins can be administered intravenously?

    regular insulin

  • 73

    Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitors block glucose reabsorption in the kidney thereby increasing its excretion thru urine. The most common ADR is:

    UTI

  • 74

    Common ADR of alpha glucosidase inhibitors such as Acarbose.

    Flatulence

  • 75

    The following belongs to first generation sulfonylureas, except:

    Torsemide

  • 76

    Which of the following drugs block the degradation of glucagon-like polypeptide-1?

    Saxagliptin

  • 77

    Which of the following classes of compounds directly stimulates the release of insulin from pancreatic beta cells?

    Sulfonylureas

  • 78

    Which of the following is a synthetic analogue of human glucagon-like polypeptide-1 that increases insulin secretion and reduces glucagon secretion?

    Exenatide

  • 79

    All of the following substances are endogenous tropic hormones secreted by the pituitary gland except

    Human chorionic gonadotropin (hCG)

  • 80

    Which of the following compounds is incorrectly matched with its mechanism of action?

    Pioglitazone: competitively blocks the binding of estrogens to their receptor

  • 81

    Which of the following compounds is incorrectly matched with one of its therapeutic uses?

    Raloxifene: ovulation induction

  • 82

    Agents used to treat hypercalcemia include I. Vitamin D III. Alendronate II. Calcitonin

    II, & III

  • 83

    Which of the following drugs should a patient avoid if he has previously experienced an allergic type of reaction to aspirin? I. Naproxen III. Ketoprofen II. Paracetamol

    I & III

  • 84

    The selective cyclooxygenase (COX) 2 inhibitors have been associated with which of the following adverse drug reactions?

    Cardiovascular thrombotic events

  • 85

    Which of the following antigout medications acts by decreasing serum levels but increasing urine levels of uric acid, thus increasing the risk of kidney stone development?

    Probenecid

  • 86

    A 22-year-old female presents with sneezing, watery and itchy eyes, and a runny nose. She has no significant medical history, but she is in the midst of final exams and must remain alert. What would be the best recommendation for her symptoms?

    Fexofenadine

  • 87

    A leukotriene modifier that inhibits the action of 5-lipoxygenase.

    Zileuton

  • 88

    Which corticosteroid is most appropriate to administer to a woman in preterm labor to accelerate fetal lung maturation?

    Betamethasone

  • 89

    Which of the following prostaglandin analogs is used specifically for the treatment of glaucoma?

    Latanoprost

  • 90

    This prostaglandin analog is an abortifacient but can also be used to manage NSAID-induced peptic ulcers.

    Alprostadil

  • 91

    Which of the antacids below causes diarrhea?

    Magnesium hydroxide

  • 92

    Which of the following drugs, based on its mechanism of action, is effective in treating diarrhea-predominant irritable bowel syndrome (IBS)?

    Alosetron

  • 93

    Which of the following is the main physical hazard when administering parenteral drugs with vesicant properties?

    Extravasation

  • 94

    Aldrich-Mees lines are a sign of what poisoning?

    Arsenic

  • 95

    Antidote for Lead poisoning

    EDTA

  • 96

    What chemical antidote is best given for Wilson's disease?

    Penicillamine

  • 97

    Methanol toxicity causes blindness due to the formation of

    Formic acid

  • 98

    A healthy 2-year-old boy ingested one of his mother's 2 mg clonazepam tablets 1 hour ago. The child presented to the emergency department with CNS depression but a normal heart rate and blood pressure. His bedside glucose checkis also normal. Which antidote might be helpful?

    Flumazenil

  • 99

    Cyanide intoxication is best managed by which drug?

    Hydroxocobalamin

  • 100

    Toxic metabolite of acetaminophen which causes hepatotoxicity

    NAPQI

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    問題一覧

  • 1

    The intensity of the pharmacological action of the drug is most dependent on ____________.

    Concentration of the drug at the receptor site.

  • 2

    True for an antagonist: I. No affinity II. No intrinsic activity III. Initiates biological response

    II

  • 3

    When a drug has narrow therapeutic index, it indicates that a drug is

    Less safe

  • 4

    If 1 mg of lorazepam produces the same anxiolytic response as 10 mg of diazepam, which is correct?

    Lorazepam is more potent than diazepam.

  • 5

    In the presence of picrotoxin, diazepam is less efficacious at causing sedation, regardless of the dose. Picrotoxin has no sedative effect, even at the highest dose. Which of the following is correct regarding these agents?

    Picrotoxin is a non competitive antagonist.

  • 6

    Which of the following describes the action of Protamine against Heparin?

    Chemical antagonism

  • 7

    True regarding active transport:

    AOTA

  • 8

    All of the following statements regarding drug transport are true except

    High molecular weight drugs diffuse across cell membrane more easily than low molecular weight drugs.

  • 9

    Administration of a sulfonamide antibiotic may displace bilirubin from binding sites on which of the following substances, leading to passage of bilirubin into the brain and the development of kernicterus?

    albumin

  • 10

    All of the following statements about plasma protein binding of a drug are true except which one?

    Drugs that are highly bound to plasma proteins generally have a greater VD compared with drugs that are highly bound to tissue proteins.

  • 11

    Food delays gastric emptying time. What effect does this have on absorption of orally administered drugs?

    Decreased absorption

  • 12

    According to Biopharmaceutics Classification System (BCS), a drug with high solubility and low permeability belongs to:

    Class 3

  • 13

    Pharmaceutical equivalent drug products must have the same ____________. I. Therapeutically active drug ingredients II. Salts or ester III. Dosage form and strength

    I, II & III

  • 14

    Drug metabolism happens in most cases, to convert the drug to a compound that is ____________. I. More polar II. More non-polar III. More lipid-soluble IV. More water-soluble

    I & IV

  • 15

    Pathway of drug biotransformation where it introduces or exposes a functional group on the drug molecules

    Phase 1

  • 16

    Isoniazid undergoes what type of conjugation reaction?

    Acetylation

  • 17

    Chloramphenicol is considered to be toxic in infants. This is due to tissue accumulation of unchanged chloramphenicol, resulting from an immature metabolic pathway. Which of the following enzymes would most likely be deficient?

    Glucuronosyltransferase

  • 18

    Inducers: I. Increase drug metabolizing enzymes II. Decrease drug metabolizing enzymes III. Increase plasma drug concentration of another drug IV. Decrease plasma drug concentration of another drug

    I & IV

  • 19

    Human milk is more acidic than plasma. Which of the following statements are true given this condition? I. Weak acid may diffuse into the breast milk and ionize. II. Weak acid may diffuse into the breast milk and remain unionized. III. Weak base may diffuse into the breast milk and ionize. IV. Weak base may diffuse into the breast milk and remain unionized

    II & III

  • 20

    The excretion of a weakly acidic drug is generally more rapid in alkaline urine than in acidic urine. This process occurs because I. A weak acid in alkaline media will exist primarily in its ionized form, which cannot be reabsorbed easily. II. A weak acid in alkaline media will exist in its lipophilic form, which cannot be reabsorbed easily. III. All drugs are excreted more rapidly in an alkaline urine.

    I only

  • 21

    The renal clearance of inulin is used as a measurement of

    GFR

  • 22

    A drug that will prevent the storage of cholinergic transmitter in vesicles thereby depleting the transmitter at the synapse.

    Vesamicol

  • 23

    This drug inhibits the release of acetylcholine. Has cosmetic use and is particularly important in treating strabismus and blepharospasms.

    Botox

  • 24

    The only adrenoceptor that is presynaptic in location

    Alpha 2

  • 25

    Ritodrine works as a tocolytic by activating this receptor

    Beta 2

  • 26

    Which of the following ingredients of a cough and cold preparation is classified as a decongestant.

    Phenylephrine

  • 27

    All of the following adverse effects are manifestations of cholinergic agonists except

    Xerostomia

  • 28

    An indirect acting cholinomimetic used in the diagnosis of myasthenia gravis.

    Edrophonium

  • 29

    The following are signs and symptoms of Organophosphate poisoning except

    Tachycardia

  • 30

    Toxicity of atropine can be managed by giving

    Physostigmine

  • 31

    Most of the drugs used in the treatment of Alzheimer’s disease are designed to produce ____________ effects.

    Cholinergic

  • 32

    An endogenous catecholamine that is used as the DOC for septic shock

    NE

  • 33

    Amphetamine exemplifies the pharmacologic mechanism of

    facilitation of transmitter release

  • 34

    A 58-year-old white male who has a history of essential hypertension and bronchial asthma has recently been diagnosed with prostatic hypertrophy. His medication history includes the following drugs: I. Propranolol IV. Finasteride II. Ipratropium V. Prazosin III. Metaproterenol Which agent would be most likely to cause postural hypotension?

    V

  • 35

    This dopamine 1 agonist can be used for hypertensive emergency due to its vasodilating effect

    Fenoldopam

  • 36

    Blood pressure of 120/90 mm Hg falls under what category of hypertension?

    Stage 1

  • 37

    James Dean went to the barangay clinic because he had been complaining of severe headaches, dizziness, and chest pain. Upon examination, the doctor diagnosed him with hypertension of unknown cause. Patients in whom no specific cause of hypertension can be found are said to have:

    Primary HTN

  • 38

    The following can be given to patients with hypertension and asthma except

    Nadolol

  • 39

    The pharmacologic profile of carvedilol is most similar to that of

    Labetalol

  • 40

    Norvasc ®

    Amlodipine

  • 41

    Prodrugs except

    Captopril

  • 42

    Angiotensin receptor antagonists or blockers (ARBs) are less likely to cause angioedema and cough than the angiotensin-converting enzyme inhibitors (ACEI) because

    ARBs do not inhibit the breakdown of bradykinin.

  • 43

    The following can give rise to birth defects except

    Methyldopa

  • 44

    Which of the following antihypertensives does not act at autonomic receptors?

    Hydralazine

  • 45

    Class of diuretics that commonly causes ototoxicity.

    Loop diuretics

  • 46

    Which of the following diuretics is contraindicated in patients with increased calcium levels in the blood?

    Chlorthalidone

  • 47

    It interferes with collecting tubular aldosterone-mediated sodium–potassium exchange and may cause hyperkalemia, gynecomastia, and menstrual irregularities.

    Spironolactone

  • 48

    The principal site of action of this drug is on the thick ascending limb of the loop of Henle. It is useful in treating pulmonary edema.

    Furosemide

  • 49

    Visual disturbances (yellow or green vision), confusion, anorexia, vomiting, atrioventricular (AV) block, and ventricular tachycardia are adverse effects of

    Cardiac glycosides

  • 50

    Antidote for Digoxin toxicity.

    AOTA

  • 51

    Which of the following pairings of an unwanted effect and the causative drug are true? I. Headache with Nitrates II. Cough with Irbesartan III. Lupus-like syndrome with Hydralazine

    I & III

  • 52

    Odd one out

    Enoxaparin

  • 53

    Close monitoring of anticoagulants is essential to prevent life-threatening effects such as bleeding. What should be monitored during Heparin therapy?

    aPTT

  • 54

    Prototype drug that prevents thromboxane A2 formation by inhibiting COX-1.

    Aspirin

  • 55

    All of the following agents have actions on blood platelets to modify clot formation except

    Dabigatran

  • 56

    Drug of choice for hypercholesterolemia

    HMG-CoA Reductase inhibitors

  • 57

    Much of the reduction in circulating LDL during treatment with simvastatin may be due to

    upregulation of HMG-CoA reductase

  • 58

    The following can be taken any time of the day except

    Pravastatin

  • 59

    Tyramine-containing food may cause dangerous hypertension in patients on this agent. I. Tranylcypromine IV. Fluoxetine II. Imipramine V. Phenelzine III. Buspirone

    l & V

  • 60

    A 38-year-old man has a history of affective disorders, including schizophrenia, depression, obsessive–compulsive disorder, and situational anxiety. His current medication profile includes the following drugs: I. Clozapine III. Buspirone II. Fluoxetine IV. Amoxapine Which agent is most likely being used to treat depression and obsessive– compulsive disorder?

    II

  • 61

    The following selectively block serotonin transporter except

    Doxepine

  • 62

    Which of the following agents is not used to treat anxiety?

    Thioridazine

  • 63

    The primary concern with opioid use during surgical procedures and overdose is the potential for significant respiratory and CNS depression leading to coma. This can be managed by the administration of opioid antagonists such as nalbuphine.

    First statement is correct

  • 64

    Which of the following drug combinations could work cooperatively to enhance a clinical anti-parkinsonian response?

    Levodopa and carbidopa

  • 65

    Which of the following statements are true regarding the similarities of Phenytoin and Phenobarbital? I. They have anti-epileptic effects II. They are enzyme inhibitors III. They both have low therapeutic indices

    I & III

  • 66

    Certain drugs are sometimes incorporated into local anesthetic solutions to prolong their activity and reduce their systemic toxicity. These drugs include I. Dobutamine II. Phenoxybenzamine III. Epinephrine

    III only

  • 67

    Which element is used in the management of Rheumatoid Arthritis?

    Gold

  • 68

    Cold intolerance and slowing down of metabolism are symptoms of?

    Hypothyroidism

  • 69

    All of the following can be used to treat hypothyroidism except

    Methimazole

  • 70

    The preferred drug given in the first trimester of pregnant patients with hyperthyroidism

    Propylthiouracil (PTU)

  • 71

    Which of the following preparations is a peakless insulin?

    Insulin Glargine

  • 72

    Which of the following insulins can be administered intravenously?

    regular insulin

  • 73

    Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitors block glucose reabsorption in the kidney thereby increasing its excretion thru urine. The most common ADR is:

    UTI

  • 74

    Common ADR of alpha glucosidase inhibitors such as Acarbose.

    Flatulence

  • 75

    The following belongs to first generation sulfonylureas, except:

    Torsemide

  • 76

    Which of the following drugs block the degradation of glucagon-like polypeptide-1?

    Saxagliptin

  • 77

    Which of the following classes of compounds directly stimulates the release of insulin from pancreatic beta cells?

    Sulfonylureas

  • 78

    Which of the following is a synthetic analogue of human glucagon-like polypeptide-1 that increases insulin secretion and reduces glucagon secretion?

    Exenatide

  • 79

    All of the following substances are endogenous tropic hormones secreted by the pituitary gland except

    Human chorionic gonadotropin (hCG)

  • 80

    Which of the following compounds is incorrectly matched with its mechanism of action?

    Pioglitazone: competitively blocks the binding of estrogens to their receptor

  • 81

    Which of the following compounds is incorrectly matched with one of its therapeutic uses?

    Raloxifene: ovulation induction

  • 82

    Agents used to treat hypercalcemia include I. Vitamin D III. Alendronate II. Calcitonin

    II, & III

  • 83

    Which of the following drugs should a patient avoid if he has previously experienced an allergic type of reaction to aspirin? I. Naproxen III. Ketoprofen II. Paracetamol

    I & III

  • 84

    The selective cyclooxygenase (COX) 2 inhibitors have been associated with which of the following adverse drug reactions?

    Cardiovascular thrombotic events

  • 85

    Which of the following antigout medications acts by decreasing serum levels but increasing urine levels of uric acid, thus increasing the risk of kidney stone development?

    Probenecid

  • 86

    A 22-year-old female presents with sneezing, watery and itchy eyes, and a runny nose. She has no significant medical history, but she is in the midst of final exams and must remain alert. What would be the best recommendation for her symptoms?

    Fexofenadine

  • 87

    A leukotriene modifier that inhibits the action of 5-lipoxygenase.

    Zileuton

  • 88

    Which corticosteroid is most appropriate to administer to a woman in preterm labor to accelerate fetal lung maturation?

    Betamethasone

  • 89

    Which of the following prostaglandin analogs is used specifically for the treatment of glaucoma?

    Latanoprost

  • 90

    This prostaglandin analog is an abortifacient but can also be used to manage NSAID-induced peptic ulcers.

    Alprostadil

  • 91

    Which of the antacids below causes diarrhea?

    Magnesium hydroxide

  • 92

    Which of the following drugs, based on its mechanism of action, is effective in treating diarrhea-predominant irritable bowel syndrome (IBS)?

    Alosetron

  • 93

    Which of the following is the main physical hazard when administering parenteral drugs with vesicant properties?

    Extravasation

  • 94

    Aldrich-Mees lines are a sign of what poisoning?

    Arsenic

  • 95

    Antidote for Lead poisoning

    EDTA

  • 96

    What chemical antidote is best given for Wilson's disease?

    Penicillamine

  • 97

    Methanol toxicity causes blindness due to the formation of

    Formic acid

  • 98

    A healthy 2-year-old boy ingested one of his mother's 2 mg clonazepam tablets 1 hour ago. The child presented to the emergency department with CNS depression but a normal heart rate and blood pressure. His bedside glucose checkis also normal. Which antidote might be helpful?

    Flumazenil

  • 99

    Cyanide intoxication is best managed by which drug?

    Hydroxocobalamin

  • 100

    Toxic metabolite of acetaminophen which causes hepatotoxicity

    NAPQI