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100問 • 1年前
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  • 1

    Which of the following pair of amino acids undergoes direct deamination?

    Serine and Glycine

  • 2

    Claviceps purpurea is a fungus which infects crop plants. Arrange the process ofinfection. I. Some of the hyphal strands produce asexual spores, known as conidiospores, which become suspended in a viscous, sugary liquid, known as honeydew II. Insects are attracted to this honeydew and carry it and the spores to other host plants, where the process is repeated. III. Spores comes into contact with the ovary of a grass, frequently rye, where it germinates, forming hyphal strands that penetrate into the host tissue. IV. The hyphae eventually form a mass of tissue known as a mycelium, which supplants the ovary. V. Honeydew is secreted by the mycelium.

    III-IV-I-V-II

  • 3

    The process of synthesis of glucose and other carbohydrate molecules from simple precursors.

    Photosynthesis

  • 4

    Glycolysis: EMP pathway; Photosynthesis:

    Calvin cycle

  • 5

    What is the product of light reaction?

    ATP and NADPH

  • 6

    The site of the Calvin cycle reactions

    Chloroplast

  • 7

    During the Krebs Cycle, which step directly produces GTP, which can be converted into ATP?

    Succinyl CoA to Succinate

  • 8

    The following are products of Krebs cycle.

    3 NADH, 1 FADH2 and 1 GTP

  • 9

    Which intermediate of the citric acid cycle is used for the synthesis of heme?

    Succinyl-CoA

  • 10

    Which step in the Krebs cycle involves substrate-level phosphorylation?

    Succinyl-CoA to Succinate

  • 11

    The conversion of isocitrate to α-ketoglutarate is possible because of what chemical reaction?

    Oxidative decarboxylation

  • 12

    An amino acid relevant to the production of heme.

    Glycine

  • 13

    Arrange the process of curing of Vanilla. I. Upon developing correct moisture level and aroma, the pods are laid in the open air, alternating between sun and shade, driving out moisture without overly drying the pods. II. The soaked pods are wrapped in woolen blankets in the day and packed in wool- covered boxes at night until the pods lose 70-80% of their original weight. III. The ripe vanilla pods are dipped into warm water for about 3 minutes IV. The pods are then graded and tied into bundles stored and sealed in closed boxes (e.g. tin containers) for shipment V. The fruits are collected as they ripen to a yellow color, 6 to 10 months after pollination.

    V-III-II-I-IV

  • 14

    Complete the general enzyme reaction scheme: E + S ⇆ ES →___

    E+P

  • 15

    This tradionally used herbal plant is used to aid cough, STOMACH ULCERS, and has been shown to exhibit ANTI-INFLAMMATORY properties.

    Glycyrrhiza glabra

  • 16

    The Lineweaver-Burke plot below is typical for a substrate with what type of inhibitor?

    Non-competitive

  • 17

    The source of thebaine

    P. bracteatum

  • 18

    Which of the following is the catalytic strategy exhibited by chymotrypsin?

    Promotion of a reaction that is immeasurably slow at neutral pH

  • 19

    Quinine is from a plant family called:

    Rubiaceae

  • 20

    The consumption of this traditionally herbal plant would cause an additive effect when taken with OHAs.

    Momordica charantia

  • 21

    The Cori cycle primarily involves the conversion of:

    Glucose to lactate in muscle cells and lactate to glucose in the liver.

  • 22

    Which of the following enzymes is involved in the "committed step" of glycolysis?

    Phosphofructokinase-1

  • 23

    At the end of glycolysis, three two-carbon fragments are produced.

    Not true

  • 24

    Which step in the glycolysis pathway produces NADH?

    Conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate

  • 25

    In the glycolysis pathway, which enzyme is responsible for the first ATP-generating step via substrate-level phosphorylation?

    Phosphoglycerate kinase

  • 26

    Fats are chemically classified as:

    Ester

  • 27

    Eicosanoids are chemically classified as:

    Carboxylic acid

  • 28

    Cytosine and Guanine are bonded by three hydrogen bonds while Adenine and Thymine are bonded by two hydrogen bonds.

    Not false

  • 29

    A nucleoside is composed of a nitrogen base, a sugar and a phosphate, while a nucleotide is composed of a nitrogen base and sugar.

    False

  • 30

    The following codons halts translation except:

    AUG

  • 31

    Glucose + Fructose + Glucose

    Melezitose

  • 32

    The following are trisaccharides, except?

    Stachyose

  • 33

    Test for aromatic amino acids

    Xanthoproteic

  • 34

    Using this test, proline would manifest a yellow color.

    Xanthoproteic

  • 35

    The following amino acids shows positive test result to lead acetate test: I. Ala III. Lys II. Met IV. Cys

    II, IV

  • 36

    Most monosaccharides often found in nature are in what form?

    Dextrorotatory

  • 37

    Most amino acids often found in nature are in what form?

    Levorotatoy

  • 38

    Special secretory tissue present in Pine trees.

    Schizogenous and lyzigenous passages

  • 39

    The volatile oils of orange are secreted from:

    Schizogenous and lyzigenous passages

  • 40

    The structure below is classified as:

    Tropane alkaloids

  • 41

    The structure below is classified as:

    Isoquinoline alkaloids

  • 42

    This class of alkaloids are widely known for their ability to inhibit parasympathetic effects.

    Tropane alkaloids

  • 43

    Odd one out:

    Pilocarpine

  • 44

    An anti-malarial and anti-arrhythmic alkaloid.

    Quinine

  • 45

    The following are liquid alkaloids except:

    Codeine

  • 46

    Purine alkaloids, except:

    Coca

  • 47

    Tropane alkaloids, except:

    Codeine

  • 48

    Camellia sinensis belongs to which class of alkaloids?

    Purine

  • 49

    Test for the presence of caffeine

    Murexide

  • 50

    A development of purple color in Marquis test indicates the presence of:

    Opium

  • 51

    Test for quinine

    Thalleoquin

  • 52

    Turpentine oil can be isolated via:

    Water distillation

  • 53

    Oil from Eugenia caryophyllus can be isolated via

    Both Water and Steam Distillation

  • 54

    Site of translation.

    Ribosome

  • 55

    Site of transcription.

    Nucleus

  • 56

    Primarily the site of post-translational modification.

    Golgi bodies

  • 57

    A codon is a three-nucleotide sequence on a tRNA molecule that is complementary to an anticodon on an mRNA molecule.

    False

  • 58

    Identify the type of mutation ATCGTTAGCCGA ATCTTAGCCGAA

    Frameshift; Deletion

  • 59

    59. Identify the type of mutation TCTCAAAAATTTACG TCTCAAATATTTACG

    Point; Transversional

  • 60

    Identify the type of mutation UCUCAAAAAUUUUCA UCUCAAAAAUUUUGA

    Nonsense

  • 61

    Which of the following is derived during transcription to convert this nucleutide chain into protein? ATTCGTCTTCACAT

    UAAGCAGAAGUGUA

  • 62

    RNA nitrogen bases, except:

    Thymine

  • 63

    The following are true, except:

    Nucleic acids are made of 6-carbon sugar, a nitrogen base, and a phosphate group

  • 64

    The simplest glycolipid

    Cerebroside

  • 65

    This type of glycolipid contains 2 or more monosaccharides, a sphingosine, and a fatty acid.

    Globosides

  • 66

    The following are essential fatty acids:

    Both Linoleic acid and α -Linolenic acid

  • 67

    This element serves as a co-factor for carbonic anhydrase

    Zinc

  • 68

    Which is correcly paired?

    Frankincense: Oleogumresin

  • 69

    Gums are physiologic products. Resins are pathological products.

    Both statements are not correct

  • 70

    The following are components of CBT, except:

    Peru balsam

  • 71

    Odd one out

    Paclitaxel

  • 72

    Which of the following is incorrectly matched:

    Theobromine: 3,7-diethylxanthine

  • 73

    Among the 4 ETC complexes, which is the one being attacked by the cyanide ion?

    Complex IV

  • 74

    The major branch point intermediate of Shikimic acid pathway.

    Chorismate

  • 75

    Statins work by inhibiting which enzyme in the mevalonic acid pathway?

    HMG coA reductase

  • 76

    This condition is characterized by the accumulation of urate in joints and kidney along with compulsive destructive behaviour, mental deficiency and spasticity. This condition is due to the condition of hyphoxanthine-gunanine phosphoribosyltransferase.

    Lesch-Nyhan syndrome

  • 77

    Adenosine Deaminase Deficiency

    Severe Combined Immunodeficiency

  • 78

    Which of the following does not stimulate lipolysis.

    Insulin

  • 79

    A condition characterized by a deficiency of muscle phosphofructokinase and a modest accumulation of glycogen.

    GSD VII

  • 80

    Major type of membrane lipid

    Phospholipid

  • 81

    An achiral amino acid which is also an inhibitory neurotransmitter.

    Glycine

  • 82

    The following are essential amino acids except:

    Y

  • 83

    The synthesis of aromatic compounds in plants is done via shikimic acid pathway. These includes aromatic amino acids such as:

    AOTA

  • 84

    A deficiency of alpha-ketoacid dehydrogenase causes a disease called Maple syrup urine odor. Which of the following amino acids’ toxic metabolites are excreted via the urine in this condition?

    AOTA

  • 85

    An enzyme synthesised by chief cells in stomach of mammals and a key component of a complex set of enzymes used in cheese production.

    Rennin

  • 86

    The inactive form of a proteolytic enzyme found in the intestine.

    Trypsinogen

  • 87

    The inactive form of a proteolytic enzyme found in the stomach.

    Pepsinogen

  • 88

    88. A homoglycan used as a diagnostic aid for renal dysfunction.

    Inulin

  • 89

    Scurvy is a disease common to sailors who had no access to fresh food supplies. This disease is caused by lack of:

    Vitamin C

  • 90

    Vitamin used as antidote of choice for acute cyanide poisoning.

    Vitamin B12

  • 91

    A vitamin administered to neonates to prevent bleeding

    Phylloquinone

  • 92

    The following are marine gums except:

    Xanthan

  • 93

    Which of the following statements are mismatched? I. Camptotheca acuminata: Topoisomerase I inhibition II. Taxus brevifolia: Topoisomerase II inhibition III. Catharanthus roseus: Microtubule polymerization inhibition IV. Podophyllum peltatum: Microtubule depolymerization inhibition

    II and IV

  • 94

    In an ATP molecule, the bond responsible for storing energy is called:

    Phospho-anhydride bonds

  • 95

    Ester of a long-chain fatty acid and a long- chain organic compound with hydroxyl groups

    Wax

  • 96

    The simplest method on preserving crude drugs.

    Exposure to 65⁰C

  • 97

    In determining the presence of cardiac glycosides in a sample, which test is most appropriate?

    Keller-Killiani

  • 98

    Which of the following sugars will test negative in Fehling’s test?

    Sucrose

  • 99

    Mucic acid test is a test for:

    Galactose

  • 100

    The use of this test is significant in diagnosing Diabetes mellitus.

    Benedict’s test

  • Module 2 Part 1

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    BCS

    BCS

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    BCS

    BCS

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    Routes of Administration

    Routes of Administration

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    Routes of Administration

    Routes of Administration

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    Pharmacokinetics

    Pharmacokinetics

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    Pharmacokinetics

    Pharmacokinetics

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    Enzyme Inducers and Enzyme Inhibitors

    Enzyme Inducers and Enzyme Inhibitors

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    Enzyme Inducers and Enzyme Inhibitors

    Enzyme Inducers and Enzyme Inhibitors

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    Metabolism and Excretion

    Metabolism and Excretion

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    Metabolism and Excretion

    Metabolism and Excretion

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    PHARMACODYNAMICS

    PHARMACODYNAMICS

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    PHARMACODYNAMICS

    PHARMACODYNAMICS

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    Ramdom

    Ramdom

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    Ramdom

    Ramdom

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    A. Parasympathetic (Cholinergic) Drugs

    A. Parasympathetic (Cholinergic) Drugs

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    A. Parasympathetic (Cholinergic) Drugs

    A. Parasympathetic (Cholinergic) Drugs

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    3

    3

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    3

    3

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    4

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    4

    4

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    Module 3 Rationales

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    Terms

    Terms

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    Terms

    Terms

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    Excipients

    Excipients

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    Excipients

    Excipients

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    Module 4

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    Module 4

    Module 4

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    Flavors,Sweeteners, and Colors

    Flavors,Sweeteners, and Colors

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    Flavors,Sweeteners, and Colors

    Flavors,Sweeteners, and Colors

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    Module 5

    Module 5

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    Module 5

    Module 5

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    Anti Glaucoma

    Anti Glaucoma

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    Anti Glaucoma

    Anti Glaucoma

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    B. Parasympathetic (Cholinergic) Blockers — Anti Cholinergic Agents

    B. Parasympathetic (Cholinergic) Blockers — Anti Cholinergic Agents

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    B. Parasympathetic (Cholinergic) Blockers — Anti Cholinergic Agents

    B. Parasympathetic (Cholinergic) Blockers — Anti Cholinergic Agents

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    C. Sympathetic (Adrenergic) Drugs

    C. Sympathetic (Adrenergic) Drugs

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    C. Sympathetic (Adrenergic) Drugs

    C. Sympathetic (Adrenergic) Drugs

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    D. Sympathetic (Adrenergic) BLOCKERS

    D. Sympathetic (Adrenergic) BLOCKERS

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    D. Sympathetic (Adrenergic) BLOCKERS

    D. Sympathetic (Adrenergic) BLOCKERS

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    E. Nicotinic Receptor Blockers

    E. Nicotinic Receptor Blockers

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    E. Nicotinic Receptor Blockers

    E. Nicotinic Receptor Blockers

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    F. Central Muscle Relaxants (or Spasmolytic agents)

    F. Central Muscle Relaxants (or Spasmolytic agents)

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    F. Central Muscle Relaxants (or Spasmolytic agents)

    F. Central Muscle Relaxants (or Spasmolytic agents)

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    Rationale Quiz 1.0

    Rationale Quiz 1.0

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    Rationale Quiz 1.0

    Rationale Quiz 1.0

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    A. Anxiolytic Agents

    A. Anxiolytic Agents

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    A. Anxiolytic Agents

    A. Anxiolytic Agents

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    B.1 Drugs for Depression

    B.1 Drugs for Depression

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    B.1 Drugs for Depression

    B.1 Drugs for Depression

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    B.2 Drugs for Mania / Bipolar Disorder

    B.2 Drugs for Mania / Bipolar Disorder

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    B.2 Drugs for Mania / Bipolar Disorder

    B.2 Drugs for Mania / Bipolar Disorder

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    C. Drugs for Psychoses - Typical and Atypical Antipsychotics

    C. Drugs for Psychoses - Typical and Atypical Antipsychotics

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    C. Drugs for Psychoses - Typical and Atypical Antipsychotics

    C. Drugs for Psychoses - Typical and Atypical Antipsychotics

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    D. Drugs for Seizure Disorders

    D. Drugs for Seizure Disorders

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    D. Drugs for Seizure Disorders

    D. Drugs for Seizure Disorders

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    E. General Anesthetics

    E. General Anesthetics

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    E. General Anesthetics

    E. General Anesthetics

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    G. Anti-Parkinson Drugs

    G. Anti-Parkinson Drugs

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    G. Anti-Parkinson Drugs

    G. Anti-Parkinson Drugs

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    H. Drugs for Alzheimer's Disease

    H. Drugs for Alzheimer's Disease

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    H. Drugs for Alzheimer's Disease

    H. Drugs for Alzheimer's Disease

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    Rationale Quiz 2

    Rationale Quiz 2

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    Rationale Quiz 2

    Rationale Quiz 2

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    1

    1

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    1

    1

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    2

    2

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    2

    2

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    3

    3

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    3

    3

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    4

    4

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    4

    4

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    5

    5

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    5

    5

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    6

    6

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    6

    6

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    1. Diuretics

    1. Diuretics

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    1. Diuretics

    1. Diuretics

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    2. Angiotensin Blockers

    2. Angiotensin Blockers

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    2. Angiotensin Blockers

    2. Angiotensin Blockers

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    3 and 4. CCBs: Non-dihydropyridines and Vasodilators

    3 and 4. CCBs: Non-dihydropyridines and Vasodilators

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    3 and 4. CCBs: Non-dihydropyridines and Vasodilators

    3 and 4. CCBs: Non-dihydropyridines and Vasodilators

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    Module 2

    Module 2

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    Module 2

    Module 2

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    Pharmacodynamics

    Pharmacodynamics

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    Pharmacodynamics

    Pharmacodynamics

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    Drug Classes

    Drug Classes

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    Drug Classes

    Drug Classes

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    MOA

    MOA

    ユーザ名非公開 · 24問 · 1年前

    MOA

    MOA

    24問 • 1年前
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    5. Sympatholytics

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    5. Sympatholytics

    11問 • 1年前
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    B. Drugs for Heart Failure

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    ユーザ名非公開 · 45問 · 1年前

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    E. Diabetes Mellitus

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    F. Drugs for osteoporosis

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    F. Drugs for osteoporosis

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    Rationale Quiz

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    問題一覧

  • 1

    Which of the following pair of amino acids undergoes direct deamination?

    Serine and Glycine

  • 2

    Claviceps purpurea is a fungus which infects crop plants. Arrange the process ofinfection. I. Some of the hyphal strands produce asexual spores, known as conidiospores, which become suspended in a viscous, sugary liquid, known as honeydew II. Insects are attracted to this honeydew and carry it and the spores to other host plants, where the process is repeated. III. Spores comes into contact with the ovary of a grass, frequently rye, where it germinates, forming hyphal strands that penetrate into the host tissue. IV. The hyphae eventually form a mass of tissue known as a mycelium, which supplants the ovary. V. Honeydew is secreted by the mycelium.

    III-IV-I-V-II

  • 3

    The process of synthesis of glucose and other carbohydrate molecules from simple precursors.

    Photosynthesis

  • 4

    Glycolysis: EMP pathway; Photosynthesis:

    Calvin cycle

  • 5

    What is the product of light reaction?

    ATP and NADPH

  • 6

    The site of the Calvin cycle reactions

    Chloroplast

  • 7

    During the Krebs Cycle, which step directly produces GTP, which can be converted into ATP?

    Succinyl CoA to Succinate

  • 8

    The following are products of Krebs cycle.

    3 NADH, 1 FADH2 and 1 GTP

  • 9

    Which intermediate of the citric acid cycle is used for the synthesis of heme?

    Succinyl-CoA

  • 10

    Which step in the Krebs cycle involves substrate-level phosphorylation?

    Succinyl-CoA to Succinate

  • 11

    The conversion of isocitrate to α-ketoglutarate is possible because of what chemical reaction?

    Oxidative decarboxylation

  • 12

    An amino acid relevant to the production of heme.

    Glycine

  • 13

    Arrange the process of curing of Vanilla. I. Upon developing correct moisture level and aroma, the pods are laid in the open air, alternating between sun and shade, driving out moisture without overly drying the pods. II. The soaked pods are wrapped in woolen blankets in the day and packed in wool- covered boxes at night until the pods lose 70-80% of their original weight. III. The ripe vanilla pods are dipped into warm water for about 3 minutes IV. The pods are then graded and tied into bundles stored and sealed in closed boxes (e.g. tin containers) for shipment V. The fruits are collected as they ripen to a yellow color, 6 to 10 months after pollination.

    V-III-II-I-IV

  • 14

    Complete the general enzyme reaction scheme: E + S ⇆ ES →___

    E+P

  • 15

    This tradionally used herbal plant is used to aid cough, STOMACH ULCERS, and has been shown to exhibit ANTI-INFLAMMATORY properties.

    Glycyrrhiza glabra

  • 16

    The Lineweaver-Burke plot below is typical for a substrate with what type of inhibitor?

    Non-competitive

  • 17

    The source of thebaine

    P. bracteatum

  • 18

    Which of the following is the catalytic strategy exhibited by chymotrypsin?

    Promotion of a reaction that is immeasurably slow at neutral pH

  • 19

    Quinine is from a plant family called:

    Rubiaceae

  • 20

    The consumption of this traditionally herbal plant would cause an additive effect when taken with OHAs.

    Momordica charantia

  • 21

    The Cori cycle primarily involves the conversion of:

    Glucose to lactate in muscle cells and lactate to glucose in the liver.

  • 22

    Which of the following enzymes is involved in the "committed step" of glycolysis?

    Phosphofructokinase-1

  • 23

    At the end of glycolysis, three two-carbon fragments are produced.

    Not true

  • 24

    Which step in the glycolysis pathway produces NADH?

    Conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate

  • 25

    In the glycolysis pathway, which enzyme is responsible for the first ATP-generating step via substrate-level phosphorylation?

    Phosphoglycerate kinase

  • 26

    Fats are chemically classified as:

    Ester

  • 27

    Eicosanoids are chemically classified as:

    Carboxylic acid

  • 28

    Cytosine and Guanine are bonded by three hydrogen bonds while Adenine and Thymine are bonded by two hydrogen bonds.

    Not false

  • 29

    A nucleoside is composed of a nitrogen base, a sugar and a phosphate, while a nucleotide is composed of a nitrogen base and sugar.

    False

  • 30

    The following codons halts translation except:

    AUG

  • 31

    Glucose + Fructose + Glucose

    Melezitose

  • 32

    The following are trisaccharides, except?

    Stachyose

  • 33

    Test for aromatic amino acids

    Xanthoproteic

  • 34

    Using this test, proline would manifest a yellow color.

    Xanthoproteic

  • 35

    The following amino acids shows positive test result to lead acetate test: I. Ala III. Lys II. Met IV. Cys

    II, IV

  • 36

    Most monosaccharides often found in nature are in what form?

    Dextrorotatory

  • 37

    Most amino acids often found in nature are in what form?

    Levorotatoy

  • 38

    Special secretory tissue present in Pine trees.

    Schizogenous and lyzigenous passages

  • 39

    The volatile oils of orange are secreted from:

    Schizogenous and lyzigenous passages

  • 40

    The structure below is classified as:

    Tropane alkaloids

  • 41

    The structure below is classified as:

    Isoquinoline alkaloids

  • 42

    This class of alkaloids are widely known for their ability to inhibit parasympathetic effects.

    Tropane alkaloids

  • 43

    Odd one out:

    Pilocarpine

  • 44

    An anti-malarial and anti-arrhythmic alkaloid.

    Quinine

  • 45

    The following are liquid alkaloids except:

    Codeine

  • 46

    Purine alkaloids, except:

    Coca

  • 47

    Tropane alkaloids, except:

    Codeine

  • 48

    Camellia sinensis belongs to which class of alkaloids?

    Purine

  • 49

    Test for the presence of caffeine

    Murexide

  • 50

    A development of purple color in Marquis test indicates the presence of:

    Opium

  • 51

    Test for quinine

    Thalleoquin

  • 52

    Turpentine oil can be isolated via:

    Water distillation

  • 53

    Oil from Eugenia caryophyllus can be isolated via

    Both Water and Steam Distillation

  • 54

    Site of translation.

    Ribosome

  • 55

    Site of transcription.

    Nucleus

  • 56

    Primarily the site of post-translational modification.

    Golgi bodies

  • 57

    A codon is a three-nucleotide sequence on a tRNA molecule that is complementary to an anticodon on an mRNA molecule.

    False

  • 58

    Identify the type of mutation ATCGTTAGCCGA ATCTTAGCCGAA

    Frameshift; Deletion

  • 59

    59. Identify the type of mutation TCTCAAAAATTTACG TCTCAAATATTTACG

    Point; Transversional

  • 60

    Identify the type of mutation UCUCAAAAAUUUUCA UCUCAAAAAUUUUGA

    Nonsense

  • 61

    Which of the following is derived during transcription to convert this nucleutide chain into protein? ATTCGTCTTCACAT

    UAAGCAGAAGUGUA

  • 62

    RNA nitrogen bases, except:

    Thymine

  • 63

    The following are true, except:

    Nucleic acids are made of 6-carbon sugar, a nitrogen base, and a phosphate group

  • 64

    The simplest glycolipid

    Cerebroside

  • 65

    This type of glycolipid contains 2 or more monosaccharides, a sphingosine, and a fatty acid.

    Globosides

  • 66

    The following are essential fatty acids:

    Both Linoleic acid and α -Linolenic acid

  • 67

    This element serves as a co-factor for carbonic anhydrase

    Zinc

  • 68

    Which is correcly paired?

    Frankincense: Oleogumresin

  • 69

    Gums are physiologic products. Resins are pathological products.

    Both statements are not correct

  • 70

    The following are components of CBT, except:

    Peru balsam

  • 71

    Odd one out

    Paclitaxel

  • 72

    Which of the following is incorrectly matched:

    Theobromine: 3,7-diethylxanthine

  • 73

    Among the 4 ETC complexes, which is the one being attacked by the cyanide ion?

    Complex IV

  • 74

    The major branch point intermediate of Shikimic acid pathway.

    Chorismate

  • 75

    Statins work by inhibiting which enzyme in the mevalonic acid pathway?

    HMG coA reductase

  • 76

    This condition is characterized by the accumulation of urate in joints and kidney along with compulsive destructive behaviour, mental deficiency and spasticity. This condition is due to the condition of hyphoxanthine-gunanine phosphoribosyltransferase.

    Lesch-Nyhan syndrome

  • 77

    Adenosine Deaminase Deficiency

    Severe Combined Immunodeficiency

  • 78

    Which of the following does not stimulate lipolysis.

    Insulin

  • 79

    A condition characterized by a deficiency of muscle phosphofructokinase and a modest accumulation of glycogen.

    GSD VII

  • 80

    Major type of membrane lipid

    Phospholipid

  • 81

    An achiral amino acid which is also an inhibitory neurotransmitter.

    Glycine

  • 82

    The following are essential amino acids except:

    Y

  • 83

    The synthesis of aromatic compounds in plants is done via shikimic acid pathway. These includes aromatic amino acids such as:

    AOTA

  • 84

    A deficiency of alpha-ketoacid dehydrogenase causes a disease called Maple syrup urine odor. Which of the following amino acids’ toxic metabolites are excreted via the urine in this condition?

    AOTA

  • 85

    An enzyme synthesised by chief cells in stomach of mammals and a key component of a complex set of enzymes used in cheese production.

    Rennin

  • 86

    The inactive form of a proteolytic enzyme found in the intestine.

    Trypsinogen

  • 87

    The inactive form of a proteolytic enzyme found in the stomach.

    Pepsinogen

  • 88

    88. A homoglycan used as a diagnostic aid for renal dysfunction.

    Inulin

  • 89

    Scurvy is a disease common to sailors who had no access to fresh food supplies. This disease is caused by lack of:

    Vitamin C

  • 90

    Vitamin used as antidote of choice for acute cyanide poisoning.

    Vitamin B12

  • 91

    A vitamin administered to neonates to prevent bleeding

    Phylloquinone

  • 92

    The following are marine gums except:

    Xanthan

  • 93

    Which of the following statements are mismatched? I. Camptotheca acuminata: Topoisomerase I inhibition II. Taxus brevifolia: Topoisomerase II inhibition III. Catharanthus roseus: Microtubule polymerization inhibition IV. Podophyllum peltatum: Microtubule depolymerization inhibition

    II and IV

  • 94

    In an ATP molecule, the bond responsible for storing energy is called:

    Phospho-anhydride bonds

  • 95

    Ester of a long-chain fatty acid and a long- chain organic compound with hydroxyl groups

    Wax

  • 96

    The simplest method on preserving crude drugs.

    Exposure to 65⁰C

  • 97

    In determining the presence of cardiac glycosides in a sample, which test is most appropriate?

    Keller-Killiani

  • 98

    Which of the following sugars will test negative in Fehling’s test?

    Sucrose

  • 99

    Mucic acid test is a test for:

    Galactose

  • 100

    The use of this test is significant in diagnosing Diabetes mellitus.

    Benedict’s test