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Metabolism and Excretion
31問 • 1年前
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    • 通報

    問題一覧

  • 1

    Oxidation

    Phase 1

  • 2

    Reduction

    Phase 1

  • 3

    Hydrolysis

    Phase 1

  • 4

    Most common metabolism in Phase 2

    Glucoronidation

  • 5

    Enzyme: Glucoronyltransferase

    Glucoronidation

  • 6

    Enzyme: N-Acetyltransferase

    Acetylation

  • 7

    Enzyme: Glutathione-S-transferase

    Glutathione Conjugation

  • 8

    Enzyme: Sulfotransferase

    Sulfation

  • 9

    Enzyme: Methyltransferase

    Methylation

  • 10

    Reaction used in conversion of Benzoic Acid to Hippuric Acid

    Glycine Conjugation

  • 11

    List the reactions that makes the drug Very Polar

    Glucoronidation, Glycine Conjugation, Glutathione Conjugation, Sulfation

  • 12

    Metabolic process present at birth

    Sulfation

  • 13

    Metabolic process present at birth

    Methylation

  • 14

    What governs the Kinetic Orders?

    Rate Law

  • 15

    Most drugs follows what Kinetic Orders?

    First-order kinetics

  • 16

    Rate is DEPENDENT on the remaining concentration

    First-order kinetics

  • 17

    Rate of metabolism becomes CONSTANT

    Zero-order kinetics

  • 18

    Constant FRACTION (100-50-25-12.5)

    First-order kinetics

  • 19

    Rate is PROPORTIONAL to the concentration

    First-order kinetics

  • 20

    Rate is INDEPENDENT on the remaining concentration

    Zero-order kinetics

  • 21

    Rate is INDEPENDENT on the remaining concentration

    Zero-order kinetics

  • 22

    Constant AMOUNT (100-95-90-85) 5-5-5-5

    Zero-order kinetics

  • 23

    Glomerular filtration

    Passive mechanism

  • 24

    Tubular secretion

    Active mechanism

  • 25

    Tubular reabsorption

    Both Passive and Active but mostly Passive mechanism

  • 26

    Filtration is non saturable

    Glomerular filtration

  • 27

    Requirement for FILTERED FORMS in Glomerular filtration

    Small / LMW, Free Drug, Can be ionized or unionized

  • 28

    primarily occurs in the proximal tubules by two energy-requiring active transport systems

    Tubular secretion

  • 29

    In Tubular reabsorption, only ________ or ________ forms are reabsorbed

    unionized or uncharged

  • 30

    Organic anion example

    deprotonated forms of weak acids

  • 31

    Organic cation example

    protonated forms of weak base

    • Module 2 Part 1

    Module 2 Part 1

    ユーザ名非公開 · 100問 · 1年前

    Module 2 Part 1

    Module 2 Part 1

    100問 • 1年前
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    Module 1

    Module 1

    ユーザ名非公開 · 13問 · 1年前

    Module 1

    Module 1

    13問 • 1年前
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    Module 2

    Module 2

    ユーザ名非公開 · 100問 · 1年前

    Module 2

    Module 2

    100問 • 1年前
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    Antibiotics

    Antibiotics

    ユーザ名非公開 · 10問 · 1年前

    Antibiotics

    Antibiotics

    10問 • 1年前
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    Module 2 Part 2

    Module 2 Part 2

    ユーザ名非公開 · 100問 · 1年前

    Module 2 Part 2

    Module 2 Part 2

    100問 • 1年前
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    Module 2 (Part 2)

    Module 2 (Part 2)

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    Module 2 (Part 2)

    Module 2 (Part 2)

    100問 • 1年前
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    Module 2 Part 3

    Module 2 Part 3

    ユーザ名非公開 · 85問 · 1年前

    Module 2 Part 3

    Module 2 Part 3

    85問 • 1年前
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    Module 4

    Module 4

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    Module 4

    Module 4

    100問 • 1年前
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    Module 4 Part 2

    Module 4 Part 2

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    Module 4 Part 2

    Module 4 Part 2

    100問 • 1年前
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    Module 4 Part 3

    Module 4 Part 3

    ユーザ名非公開 · 60問 · 1年前

    Module 4 Part 3

    Module 4 Part 3

    60問 • 1年前
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    Module 2 (Part 4)

    Module 2 (Part 4)

    ユーザ名非公開 · 68問 · 1年前

    Module 2 (Part 4)

    Module 2 (Part 4)

    68問 • 1年前
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    Randome Questions

    Randome Questions

    ユーザ名非公開 · 13問 · 1年前

    Randome Questions

    Randome Questions

    13問 • 1年前
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    1

    1

    ユーザ名非公開 · 100問 · 1年前

    1

    1

    100問 • 1年前
    ユーザ名非公開

    Module 2 (Part 5)

    Module 2 (Part 5)

    ユーザ名非公開 · 100問 · 1年前

    Module 2 (Part 5)

    Module 2 (Part 5)

    100問 • 1年前
    ユーザ名非公開

    2

    2

    ユーザ名非公開 · 100問 · 1年前

    2

    2

    100問 • 1年前
    ユーザ名非公開

    Module 2 (Part 6)

    Module 2 (Part 6)

    ユーザ名非公開 · 68問 · 1年前

    Module 2 (Part 6)

    Module 2 (Part 6)

    68問 • 1年前
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    Module 4 Part 1

    Module 4 Part 1

    ユーザ名非公開 · 5問 · 1年前

    Module 4 Part 1

    Module 4 Part 1

    5問 • 1年前
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    問題一覧

  • 1

    Oxidation

    Phase 1

  • 2

    Reduction

    Phase 1

  • 3

    Hydrolysis

    Phase 1

  • 4

    Most common metabolism in Phase 2

    Glucoronidation

  • 5

    Enzyme: Glucoronyltransferase

    Glucoronidation

  • 6

    Enzyme: N-Acetyltransferase

    Acetylation

  • 7

    Enzyme: Glutathione-S-transferase

    Glutathione Conjugation

  • 8

    Enzyme: Sulfotransferase

    Sulfation

  • 9

    Enzyme: Methyltransferase

    Methylation

  • 10

    Reaction used in conversion of Benzoic Acid to Hippuric Acid

    Glycine Conjugation

  • 11

    List the reactions that makes the drug Very Polar

    Glucoronidation, Glycine Conjugation, Glutathione Conjugation, Sulfation

  • 12

    Metabolic process present at birth

    Sulfation

  • 13

    Metabolic process present at birth

    Methylation

  • 14

    What governs the Kinetic Orders?

    Rate Law

  • 15

    Most drugs follows what Kinetic Orders?

    First-order kinetics

  • 16

    Rate is DEPENDENT on the remaining concentration

    First-order kinetics

  • 17

    Rate of metabolism becomes CONSTANT

    Zero-order kinetics

  • 18

    Constant FRACTION (100-50-25-12.5)

    First-order kinetics

  • 19

    Rate is PROPORTIONAL to the concentration

    First-order kinetics

  • 20

    Rate is INDEPENDENT on the remaining concentration

    Zero-order kinetics

  • 21

    Rate is INDEPENDENT on the remaining concentration

    Zero-order kinetics

  • 22

    Constant AMOUNT (100-95-90-85) 5-5-5-5

    Zero-order kinetics

  • 23

    Glomerular filtration

    Passive mechanism

  • 24

    Tubular secretion

    Active mechanism

  • 25

    Tubular reabsorption

    Both Passive and Active but mostly Passive mechanism

  • 26

    Filtration is non saturable

    Glomerular filtration

  • 27

    Requirement for FILTERED FORMS in Glomerular filtration

    Small / LMW, Free Drug, Can be ionized or unionized

  • 28

    primarily occurs in the proximal tubules by two energy-requiring active transport systems

    Tubular secretion

  • 29

    In Tubular reabsorption, only ________ or ________ forms are reabsorbed

    unionized or uncharged

  • 30

    Organic anion example

    deprotonated forms of weak acids

  • 31

    Organic cation example

    protonated forms of weak base