organic medicinal chemistry

Hannah Angelique Losaria · 100問 · 2年前

通報

問題一覧

what role do prodrugs play in medicinal chemistry?

serving as inactive precursors that are converted into active drugs in the body

this is the most importat organ for drug metabolism

liver

what is the conjugating agent for sulfation reaction

sulfate

which enzyme catalyzes acetylation reactions

n acetyltransferase

what is the major metabolic pathway for sulfonamides in humans

acetylation

the most important component of the mixed function oxidase system is

cytochrome p450

the most common anion used to prepare salts of organic medicines

chloride

which of the following ppathway is also known as mercapturic acid conjugation

glutathione cojugation

chhemical or physical treatment thaat destroys most vegetative microbes or viruses, but not spores, in or on inanimate suurfaces

disinfection

linezolid

oxazolidinedione

which of the following is not true regarding chloramphenicol

causes pseudomembranous colitis

colistin is a preparation of polimyxin___

ethanol that contains methanol or other txic substances such as benzene is called

denaturated alcohol

this syndromeis caused by the accumulation of free chloramphenicol in neonates or infants due to their inability to metabolize it through glucuronidation

gray baby syndrome

a colorless, flammable gas that is used to sterilize heat-sensitive medical dvices that cannot be autoclaved

ethylene oxxide

which phenol derivative is used for the tx of tinea (ringworm) infections and as keratolytic agents

resorcinol

benzoic acid and salicylic acid are components of

whitefield's ointment

an antifungal isolated originally as a "curling factor" in plants

griseofulvin

an antiviral that is obtained by fermentation with strains of streptomyces antibioticus

vidarabine

the major problem with the use of peniicillins

hypersensitivity

the p-hydroxy analog of ampicillin

amoxicillin

the beta-lactamase inhibitor present in augmentin

clavulanic acid

which of the following is not iodine-containing

formalin

atreonam is an example of

monobactam

this group of antibiotics form stable chelate complexes with metals, which will impair absorption and even bind to the calcium found in newly formed bones and teeth

tetracycline

the 6-methyl ether of erythromycin

clarithromycin

a charge-transfer complex of iodine with the non-ionic surfactant PVP

povidone iodine

the most effective of a serie of acyclic nucleosides that possessed activity against herpes simplex 2 and vvaricella zoster

acyclovir

methenamine requires an acidic ph in order to hydrolize to what active drug?

formaldehyde

which of the following mechanism is not bactericidal

protein synthesis inhibitor

mismatched

erythromycin- 50s subunit

which of the following sulfonamides is the DOC for severe traveller's diarrhea

trimethoprim- sulfamethoxazole

2,6-dimethoxyphenylpenicillin

methicillin

which of the following is not a penicillinase-resistant penicillin

pen g

which of the following can be given to patients that are allergic to penicillins

doxycycline

gentamycin belongs to the streptomycinoid group of antibiotics. it is obtained from?

m. purpurea

flouroquinolones exert thei action by targeting ___________

dna gyrase

this is consideered to be the ost effective of a series of antibacterial biguanides

chlorhexidine glucunate

which of the following antitubercular drugs is known to cause reddish orage discoloration of body fluids and permanently discolor soft contact lenses

rifampicin

agent of choice for the treatment of blood lukes (schistosomiasis)

praziquantel

how does iodine tincture differ from iodine solution

iodine tincture contains alcohol as solvent

the antimicrobial activity of chlorine anti-infectives is due to the liberation of ____________

hypochlorous acid

halazone, a chlorine-containing anti-infective, is used as a/an _________

water disinfectant

this mercury containing compound is the old active ingredient is the old active ingredient of merthiolate

thimerosal

methylparaben is a/an _______

preservative

this antifungal can be administered via the intravenous route for the treatment of severe, potentially life- threaatening funal infections

amphotericin b

which of the following is indicated for the treatmment of ringworm infections

griseofulvin

undecyclenic acid is a/an ________

antifungal

what do penicillins and cephalosporins have in common in their structure

beta-lactam ring

which of the following can be used as urinary tract anti-infectives I. nitrofurantoin II. nalidixic acid III. methenamine

I,II,III

bactrim I. trimethoprim- sulfamethoxazole II. trimethoprim- sulfisoxazole III. active ingredient against PCP

I, III

sulfonamides are active in its ______ form

ionized

these salts of penicillin are useful as depot forms to provide effective blood levels over a long period of time I. benzathine II. procaine III. hydrabamine

I, II, III

the alpha amino group in amoxicillin and ampicillin confers _________

activity against gram negative bacteria

which of the following is not a third generation cephalosphorin

cefepime

aminoglycosides such as streptomycin are known for causing this undesirable effect

ototoxicity

the amino glycosides has shown effectiveness in treating respiratory infections caused by p. aeruginosa in patients with cystic fibrosis

tobramycin

he drug of choice for mrsa

vancomycin

the following are reactive intermediates of metronidazole responsible for its antimicrobial effect, except

iodoquinol

the second line treatment for malaria in cases where artemether- lumefantrine is not available and/or there is treatment failure

quinne+ tetra/ doxy/ clinda

whih of the following is not a purine analog

cytarabine

which of the following is not an alkalyting agent

vinca alkaloids

antineoplastic agent combined with 5-fu and leucovorin as first line treatment of metastatic colon cancer

ironetican

which of the following antineoplastic agents will most likely cause congestive heart failure?

doxorubucin

the following anticancer agents are obtained from biological sources, except

busulfan

a plant metabolite classified as a mitotic inhibitor

vincristine

for endometrial cancer induced by tamoxifen, which of the following agents can be used?

medroxyprogesterone acetate

the sugar component found in nucleic acid is ______

ribose

this polysaccharide is used as a plasma expander

dextran

which of the following pharmaceutical enzymes is indicated for acute myocardial infarction

streptokinase

the folowing vaccines are prepared from inactivated virus, except I. influenza II. hepatitis a III. measles IV. mumps

III, IV

To produce the desired biological product, this vaccine is being grown in embryonated chicken eggs

mumps

which of the following natural products is used as an mulsifying agent in toothpastes

carageenan

which of the following is considered a second generation antihistamine?

levocetirizine

which is a pure opioid antagonists of all opioid receptor subtypes I. naltrexone II. naloxone III. nalbuphine IV. tramadol

I, II

which of the following is not an opiate

methadone

this functional group present in losartan and other ARBs confers acidity to the whole structure

tetrazole

which of the following herbs has been used to treat psychiatric disorders

st johns wort

silymarin is a mixture of three isomeric flavanolignans: silybin (silibinin), silychristin, and silyydianin. it is currently used as a

hepatoprotectant

the active ingredient present in st john's wort is

hypericine

which of the following substance is detected i the urine of a likely pregnant woman

human chorionic gonadotropin

a fat soluble vitamin that is used to treat acne vulgaris

tretinoin

mismatched

pge2- misoprostol

the therapeutic potency of conventional NSAIDs is highly correlated with what adverse effect?

GI toxxicity

this agent belongs to a group of drugs that are widely used as antihypertensives and are also considered first line treatments for galucoma

betaxolol

gastro

gastro

100問 • 2年前

Hannah Angelique Losaria · 7問 · 2年前

gastro m

gastro m

7問 • 2年前

Hannah Angelique Losaria · 13問 · 2年前

lab

lab

13問 • 2年前

Hannah Angelique Losaria · 94問 · 2年前

94問 • 2年前

Hannah Angelique Losaria · 88問 · 2年前

88問 • 2年前

Hannah Angelique Losaria · 50問 · 2年前

poisons

poisons

50問 • 2年前

Hannah Angelique Losaria · 19問 · 2年前

lec

lec

19問 • 2年前

Hannah Angelique Losaria · 16問 · 2年前

exam

exam

16問 • 2年前

Hannah Angelique Losaria · 41問 · 1年前

spec

spec

41問 • 1年前

Hannah Angelique Losaria · 55問 · 1年前

midterm

midterm

55問 • 1年前

Hannah Angelique Losaria · 54問 · 1年前

PHYSICAL PHARMACY

PHYSICAL PHARMACY

54問 • 1年前

Hannah Angelique Losaria · 29問 · 1年前

PHYSICAL PHARMACY II

PHYSICAL PHARMACY II

29問 • 1年前

Hannah Angelique Losaria · 33問 · 1年前

DDS

DDS

33問 • 1年前

Hannah Angelique Losaria · 22問 · 1年前

hallucinogens

hallucinogens

22問 • 1年前

Hannah Angelique Losaria · 42問 · 1年前

non volatile poisons

non volatile poisons

42問 • 1年前

Hannah Angelique Losaria · 63問 · 1年前

endterm

endterm

63問 • 1年前

Hannah Angelique Losaria · 17問 · 1年前

q3 endterm

q3 endterm

17問 • 1年前

Hannah Angelique Losaria · 65問 · 1年前

mockboard 2019

mockboard 2019

65問 • 1年前

Hannah Angelique Losaria · 39問 · 1年前

mockboard 2019 II

mockboard 2019 II

39問 • 1年前

Hannah Angelique Losaria · 36問 · 1年前

miss mel reviewer

miss mel reviewer

36問 • 1年前

Hannah Angelique Losaria · 9問 · 1年前

miss roma high yield

miss roma high yield

9問 • 1年前

Hannah Angelique Losaria · 12問 · 1年前

micro highlights

micro highlights

12問 • 1年前

Hannah Angelique Losaria · 24問 · 1年前

module 6 AUgdguwegfiuwegfu

module 6 AUgdguwegfiuwegfu

24問 • 1年前

Hannah Angelique Losaria · 75問 · 1年前

mod6 sure

mod6 sure

75問 • 1年前

manufacturing

manufacturing

Hannah Angelique Losaria · 94問 · 1年前

module 5

module 5

94問 • 1年前

Hannah Angelique Losaria · 98問 · 1年前

mod5

mod5

98問 • 1年前

5555555555

5555555555

brex

brex

Hannah Angelique Losaria · 44問 · 1年前

mod4

mod4

44問 • 1年前

Hannah Angelique Losaria · 69問 · 1年前

tox lab

tox lab

69問 • 1年前

Hannah Angelique Losaria · 59問 · 1年前

biopharmaceutics

biopharmaceutics

59問 • 1年前

Hannah Angelique Losaria · 86問 · 1年前

toxicology

toxicology

86問 • 1年前

Hannah Angelique Losaria · 49問 · 1年前

non volatile

non volatile

49問 • 1年前

Hannah Angelique Losaria · 15問 · 1年前

gosel and bricker

gosel and bricker

15問 • 1年前

Hannah Angelique Losaria · 19問 · 1年前

management of ADRs bariles

management of ADRs bariles

19問 • 1年前

Hannah Angelique Losaria · 16問 · 1年前

quiz 4

quiz 4

16問 • 1年前

Hannah Angelique Losaria · 63問 · 1年前

pcol miss gift exam

pcol miss gift exam

63問 • 1年前

Hannah Angelique Losaria · 27問 · 1年前

expirement 2- antidotes

expirement 2- antidotes

27問 • 1年前

Hannah Angelique Losaria · 28問 · 1年前

volatile poisons

volatile poisons

28問 • 1年前

Hannah Angelique Losaria · 37問 · 1年前

Drugs acting on the central nercous sytem

Drugs acting on the central nercous sytem

37問 • 1年前

Hannah Angelique Losaria · 20問 · 1年前

anti arrhythmic drugs

anti arrhythmic drugs

20問 • 1年前

Hannah Angelique Losaria · 17問 · 1年前

antiplatelet drugs

antiplatelet drugs

17問 • 1年前

Hannah Angelique Losaria · 31問 · 1年前

Cardiovascular Drugs

Cardiovascular Drugs

31問 • 1年前

Hannah Angelique Losaria · 26問 · 1年前

barbiturates

barbiturates

26問 • 1年前

Hannah Angelique Losaria · 34問 · 1年前

physical pharmacy

physical pharmacy

34問 • 1年前

plasma

plasma

Hannah Angelique Losaria · 73問 · 1年前

endterm

endterm

73問 • 1年前

Hannah Angelique Losaria · 55問 · 1年前

juris

juris

55問 • 1年前

dds

dds

Hannah Angelique Losaria · 92問 · 1年前

92問 • 1年前

Hannah Angelique Losaria · 19問 · 1年前

dddssss

dddssss

19問 • 1年前

Hannah Angelique Losaria · 59問 · 1年前

manuf

manuf

59問 • 1年前

Hannah Angelique Losaria · 67問 · 1年前

qc/qa

qc/qa

67問 • 1年前

Hannah Angelique Losaria · 83問 · 1年前

qc qa identification

qc qa identification

83問 • 1年前

quali/ quanti ppt

quali/ quanti ppt

Hannah Angelique Losaria · 23問 · 1年前

quali/quanti 2

quali/quanti 2

23問 • 1年前

Hannah Angelique Losaria · 68問 · 1年前

quali quanti identification

quali quanti identification

68問 • 1年前

Hannah Angelique Losaria · 37問 · 1年前

microbiology: introduction and bacterial anatomy

microbiology: introduction and bacterial anatomy

37問 • 1年前

Hannah Angelique Losaria · 60問 · 1年前

mocrobiology: bacterial stain, nutrition, bacterial recombination, growth phrases, microbial growth factor, culture media

mocrobiology: bacterial stain, nutrition, bacterial recombination, growth phrases, microbial growth factor, culture media

60問 • 1年前

Hannah Angelique Losaria · 28問 · 1年前

microbiology: bacteriology part 1

microbiology: bacteriology part 1

28問 • 1年前

Hannah Angelique Losaria · 48問 · 1年前

microbiology: bacteriology part 2

microbiology: bacteriology part 2

48問 • 1年前

Hannah Angelique Losaria · 20問 · 1年前

microbiology: mycology

microbiology: mycology

20問 • 1年前

Hannah Angelique Losaria · 48問 · 1年前

microbio identification 1

microbio identification 1

48問 • 1年前

Hannah Angelique Losaria · 38問 · 1年前

miss gift

miss gift

38問 • 1年前

Hannah Angelique Losaria · 21問 · 1年前

microbiology 2

microbiology 2

21問 • 1年前

Hannah Angelique Losaria · 18問 · 1年前

microbio 3

microbio 3

18問 • 1年前

microbio 4

microbio 4

Hannah Angelique Losaria · 30問 · 1年前

microbio anatomy

microbio anatomy

30問 • 1年前

Hannah Angelique Losaria · 37問 · 1年前

Drugs acting on the central nercous sytem

Drugs acting on the central nercous sytem

37問 • 1年前

Hannah Angelique Losaria · 17問 · 1年前

microbio5

microbio5

17問 • 1年前

Hannah Angelique Losaria · 13問 · 1年前

microbio6

microbio6

13問 • 1年前

Hannah Angelique Losaria · 34問 · 1年前

pub health 1

pub health 1

34問 • 1年前

Hannah Angelique Losaria · 30問 · 1年前

microbio7

microbio7

30問 • 1年前

Hannah Angelique Losaria · 31問 · 1年前

public health

public health

31問 • 1年前

Hannah Angelique Losaria · 40問 · 1年前

pacop

pacop

40問 • 1年前

Hannah Angelique Losaria · 98問 · 1年前

inorganic pharmaceutical pharmacy

inorganic pharmaceutical pharmacy

98問 • 1年前

transition metal iron triad FE CO NI

transition metal iron triad FE CO NI

Hannah Angelique Losaria · 8問 · 1年前

licensing

licensing

8問 • 1年前

Hannah Angelique Losaria · 26問 · 1年前

most common side effects

most common side effects

26問 • 1年前

chemistry people

chemistry people

pharmacognosy people

pharmacognosy people

Hannah Angelique Losaria · 29問 · 1年前

drug of choice

drug of choice

29問 • 1年前

Hannah Angelique Losaria · 19問 · 1年前

common antidotes

common antidotes

19問 • 1年前

Hannah Angelique Losaria · 25問 · 1年前

vitamin functions and deficiencies

vitamin functions and deficiencies

25問 • 1年前

Hannah Angelique Losaria · 97問 · 1年前

inorganic pharmaceutical pharmacy 2

inorganic pharmaceutical pharmacy 2

97問 • 1年前

Hannah Angelique Losaria · 42問 · 1年前

42問 • 1年前

Hannah Angelique Losaria · 62問 · 1年前

62問 • 1年前

Hannah Angelique Losaria · 48問 · 1年前

inorganic pharm chem 3

inorganic pharm chem 3

48問 • 1年前

Hannah Angelique Losaria · 66問 · 1年前

66問 • 1年前

Hannah Angelique Losaria · 60問 · 1年前

60問 • 1年前

Hannah Angelique Losaria · 43問 · 1年前

43問 • 1年前

Hannah Angelique Losaria · 79問 · 1年前

79問 • 1年前