問題一覧
1
Pge2 analog for glaucoma
latanoprost
2
SERM for tamoxefin resistant breast cancer
fulvestrant
3
Pge2 analog for abortion
dinoprostone
4
Receptor that stimulates phospholipidase c
gq
5
Intentional exposure
overdose
6
Inhibition of cyclooxygenase for clotting
aspirin and other cox inhibitors
7
Drugs for oharmacologic stress test
dobutamine, dipyridamole
8
T4
long acting, less potent
9
Posses both anti parkinsonian and antiviral activity
amantadine
10
Dependent upon the concentration of the drug
first order reaction
11
Secondary to accidental exposure to a drug
poisoning
12
Oral gold compound
auranofin
13
Less than 1 month
subacute
14
Mineral used for duarrhea that can be chelated by tetracycline
zinc
15
5ht-3 antagonist that is an antiemetic also used for management of acute migraine attacks
ondansetron
16
Bcs class ll
carbamazepine, glibenclamide
17
Irreversible inhibitors of p2yl2 receptors
clopidogrel, ticlopidine
18
Process of drug metabolism and excretion
elimination
19
B blocker that increases nitric oxide levele
nevibolol
20
SERM; fertility drug
clomiphene
21
Sildenafil and nitroglycerin causes
hypotension
22
Nsaid not effective for gout
tolmetin
23
Frequency of occurence of undesirable effects arising from exposure to a physical or chemical agent
risk
24
Opioid used against diarrhea but has lesser or no risk of dependence
loperamide
25
Prostacyclin analog usedfor the management of primary pulmonsry hypertension
epoprostenol
26
Non energy requiring Moved along concentration gradient Can be carrier mediated (fascilitated transport)
passive transport
27
Reversible adp antiplatelet
ticagrelor
28
Mitotic inhibitor
vincristine, vinblastine, paclitaxel
29
Ability to cause harm or injury in a guven situation
hazard
30
Pge1 analog for erectile dysfunction
alprostadil
31
Evidence obtained from administering the toxic substance into an animal and noting its effect
experimental evidence
32
Biologically active for of insulin
monomer
33
Neurolept anesthesia
nitrous oxide, droperidol, fentanyl
34
5-ht4 agonist used for acute migraine attacks
tegaserod
35
Aripiprazole is a
antipsychotic
36
Also known as antibodies
immunoglobins
37
Nm blockers acts specifically on whuch receptor
nicotinic
38
Dopamine is metabolized by
mao b
39
SERM for breast cancer
tamoxifen
40
Topoisomerase ll inhibitor
etoposide, teniposide
41
Rare genetic disorder that affects the skins anility to repair itself from uv damage
xeroderma pigmentosum
42
Evidence inferred from a series of events or facts, proves motives
circumstantial evidence
43
Independent from the concentration of the drug
zero order reaction
44
Severe withdrawal syndrome that can occur in people who have been heavy drinkers for a long time and abruptly stopped drinking * Hallucinations, disorientation, tremor, fever, sweating
delirium tremens
45
BCS class lV
furosemide, chlorthalidone
46
More than 3 months
chronic
47
BCS class lll
acyclovir, atenolol, cimetidine
48
Neurolept analgesia
droperidol, fentanyl
49
Mixedacting adrenergic antagonist (both alpha and beta blocking)
labetalol, carvedilol
50
Vasodilator used for management of hypertensive emergency in pregnancy, and management of chf (combined with ismd)
hydralazine
51
Lowest dose producing maximum effect
ceiling dose
52
The immune response created by the body in response to the presence of an antigen
antibody
53
Degree of changes in dose with changes in response
slope
54
Inhibition of fibrinolysis
tranexamic acid
55
Range of physical and mental health problems that can develop due to chronic heavy alcohol use *Cognitive decline, memory problems, liver damage
alcohol syndrome
56
Evidence detected using analysis
chemical evidence
57
5-ht4 agonist for ibs consti type used in management of acute migraine attacks
tegaserod
58
24 hours
acute
59
Pge1 analog for nsaid induced pud
misoprostol
60
Partial 5ht-1a agonist for anxiety also used in management of acute migraine attacks
buspirone
61
Ability to induce adverse effects
toxicity
62
Process that breaks down drugs into very fine particles
micronization
63
Less sedating antihistamines
cetirizine, levocetirizine
64
Drug concentration needed to just barey produce an effect
maximum toxic concentration
65
Condition where pre existing hyperthyroidism worsens after exposure to iodine
jod basedow phenomenon
66
A foreign substance that allows the body to create an immune response
antigen
67
Intermediate acting barbiturates
amobarbital, butabarbital
68
Long acting barbiturate
phenobarbital
69
SERM for osteoporosis
raloxefin
70
Bcs class l
paracetamol, metoprolol, theophylline
71
Rate limiting facto in the dissolution of drugs
disintegration
72
Paracetamol toxicity causes depletion of
glutathione
73
T3
short acting, more potent
74
Weak opioid for pain
tramadol
75
Inhibition of vitamin k dependent clotting factor synthesis
warfarin
76
Energy requiring Move against the concentration gradient Carrier mediated
active transport
77
Inhibition of thrombin
heparin
78
Opioid which exhibits no cardiovascular or biliary effect
mepiridine
79
Canivaptan is
vasopressin antagonist
80
An acetazolamide used by mountaineers exepriencing dizziness, insomnia, and headache, after quickly reaching the summit
diamox
81
Building blocks of rna and dna
nucleic acid
82
Storage form of insulin
hexamer
83
Bioavailability is greatly affected by
drug absorption
84
Inhibition of platelet aggregation
antiplatelet
85
Ritodrine is
tocolytic
86
Antiviral drug approved for the treatment of corona virus by the national medical products administration of china
favilavir
87
Low molecular weight heparins
fondaparinux, enoxaparin, dalteparin, tinzaparin
88
1-3 months
subchronic
89
Heparins that are safe for pregnant patient
low molecular weight
90
Measure of relative safety ( relative- in comparison to other drugs)
therapeutic index
91
Inhibition of p2yl2 receptors
clopidogrel
92
Antiarrhythmic drug that may cause hypothyroidism
amiodarone
93
Evidende obtained from the examination of organs and tissues of the dead
post mortem evidence
94
Given with atropine to decrease risk of addiction, used to treat diarrhea
diphenoxylate
95
Molecular weight protein that binds to endogenous substances before contributing to the body's immune response
hopten
96
Topoisomerase l inhibitor
irenotecan, topotecan
97
Se of hydralazine
systemic lupus, erythematosus
98
Fraction of an administered dose of a drug that reaches the systemic circulation in its active form and is available to produce its intended effect
bioavailability
99
Toxicity associated with any chemical substance
intoxication
100
Refere to efficacy
maximum achievable response