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55

92問 • 1年前

問題一覧

This defect is due to thermal expansion of tablet cores and lack of film flexibility caused by overdrying

VIII. Type 1 film cracking

This defect is often associated with exposure of tablet cores to coating process conditions rather than a direct effect of applied coating

X. Delayed dissolution of IR products

A defect due to core swelling caused by excessive moisture uptake into tablet cores during coating application.

IX. Type 2 film cracking

This happens when partially spray dried materials accumulate within the logo, causing an unclear logo design.

V. Logo infilling

This defect is caused by partial spray drying or of overwetting causing the soft coating to rub.

VII. Rough coating

This part of the tablet press distributes the granules into the table top for compression.

Feed shoe

for storing materials for compression

Hopper

guides the movement of the punches

Cam tracks

for compacting the materials within the die

Punch

controls the size and shape of the tablet

Die

Internal disintegrants are those added before granulation. On the other hand, external disintegrants are added before compression.

Both statements are true

HPMC

Film former

Castor oil

Plasticizer

TiO2

Opacifying agent

Polyethylene glycol

Alloying substance

This part of the aerosol system connects the actuator and spring

Stem

opening where the product comes out

Valve

a tube that extends from the valve to the bottom of the can so that the product under pressure is pushed out

Dip tube

holds the spring and connects the dip tube to the valve assembly

Housing

enables the user to activate the aerosol delivery system

Hydrophilic Petrolatum, USP

Absorption base

Petrolatum White petrolatum Yellow ointment White ointment

Oleaginous bases

Hydrophilic ointment

Water-removable base

Polyethylene glycol

Water-soluble base

This method of drug delivery enhances the transport of some solute molecules by creating a potential gradient through the skin with an applied electrical current or voltage.

Iontophoresis

reversible alteration of the stratum corneum to reduce its diffusional resistance.

Chemical enhancers

high-frequency ultrasound.

Sonophoresis

creates conduits for the transfer of drugs through the stratum corneum

Microfabricated microneedles

This suppository base contains triglycerides derived from coconut oil.

Witepsol

Mixed triglycerides of oleic, palmitic, stearic acids.

Cocoa butter

Triglycerides from palm, palm kernel, and coconut oils with self-emulsifying glyceryl monostearate and polyoxyl stearate.

Fattibase

A homogeneous blend of PEGs and polysorbate 80.

Polybase

Triglycerides of saturated fatty acids C12–C18 with varied portions of the corresponding partial glycerides.

Witepsol

Acts between surfaces in relative motion to prevent friction and wear and also aids the release of the tablet from the die.

Lubricant

Prevents granulations from sticking to the faces of the punches and die walls

Antiadherents

Reduces friction among particles to enhance the flow

Glidants

Promotes breaking of tablet after administration

Disintegrants

Which filling method utilizes the container as the basis for controlling the fill of each unit?

Constant level

filling according to the exact weight (for large containers OR highly viscous liquids).

Gravimetric

filling according to constant volume (not for very viscous liquids).

Volumetric

For beverages – water bottles, jars, caps Have transparency and luster Gamma radiation sterilization

1. POLYETHYLENE TEREPHTHALATE (PET)

Hard thermoset for solid dosage forms Shampoo bottles, grocery bags Resistant to leaching

2. HIGH DENSITY POLYETHYLENE (HDPE)

Rigid and good clarity For blister packaging, IV bags and tubings Cleaning products, sheetings

3.POLYVINYL CHLORIDE (PVC)

Thermoplastic for squeeze bottles and medicine droppers Bread bags, plastic films Prone to leaching

4.LOW DENSITY POLYETHYLENE (LDPE)

Autoclavable yogurt cups, straws, hangers

5.POLYPROPYLENE (PP)

General purpose and impact modified Take away and hard packaging toys

6.POLYSTYRENE (PS)

The work required to reduce the size of a given quantity of material is constant for the same reduction ratio regardless of initial size of material.

Kick’s Law

explains the drug released by dissolution relative to the changes in surface area and diameter of the particles

Hixson-Crowell

The size reduction is directly proportional to the new surface formed.

Rittinger’s

the work used to reduce the particle size is proportional to the square root of diameter of particle produced

Bond’s

What equation refers to the dissolution rate of drugs in solution?

Noyes-Whitney

For diffusion

Fick’s

Buffer solutions`

Henderson-Hasselbalch

Enzyme kinetics

Michaelis Menten

This process separates colloidal and macromolecules via membrane, driven by hydrostatic pressure

Ultrafiltration

This type of mass transfer involves the passage of individual molecules through the lipid bilayer

Transcellular diffusion

movement of substances across the epithelium through the intercellular space between the cells.

Paracellular diffusion

This separation process involves the concept of unequal rates of passage of solutes and solvent through microporous membranes

Dialysis

This is the transfer of solvent molecules through a semipermeable membrane from region of low solute to high solute concentration

Osmosis

Dispersed phase consists of Aggregates (micelles) of small organic molecules or ions whose size individually is below the colloidal range

Association colloids

Dispersed phase consists generally of large organic molecules lying within colloidal size range

Lyophilic

Dispersed phase ordinarily consists of inorganic particles, such as gold or silver

Lyophobic

Places the emulsifying agent at the interface between oil and water, surrounding the droplets of the internal phase as a thin layer of film adsorbed on the surface of the drops, the film prevents contact and coalescing of the dispersed phase.

Plastic film theory

The use of surface active agents lowers the interfacial tension of the two immiscible liquids, reducing the repellent force between the liquids and diminishing each liquids attraction for its own molecules

Surface tension theory

Assumes monomolecular layers of emulsifying agent curved around a droplet of the internal phase of the emulsion depending on the solubility of these agents in that particular liquid

Oriented wedge theory

The degrees of freedom in a one-component system consisting of Gas and Solid phases?

These begin to flow when a shear stress is applied and does not exhibit any yield value. As shear stress increases, shear rate increases

Pseudoplastic

This is a rare type of flow that causes an increase in viscosity with time

Rheopexy

An observable increase in viscosity is observed when this material is sheared

Dilatant

These do not begin to flow until shear stress to a certain value is exceeded.

Plastic

Heat necessary for 1 mole of gas, solid or liquid to change to another phase.

Latent heat

heat capacity of 1 g of substance.

Specific heat

amount of energy that must be added to a mole of solid at constant pressure to turn it into a liquid.

Heat of fusion

amount of heat required to raise the temperature of a given quantity of substance by 1oC

Heat of capacity

Determined by the displacement of Helium gas, which can penetrate into very small pores.

True

measured from the bulk volume and the weight of the dry powder in a graduated cylinder.

Bulk

ratio of the density of the powder and the density of the material.

Relative

via Hg displacement

Granule

An Act Providing for the Mandatory Philhealth Coverage for All Senior Citizens

RA 10645

Anti-Drunk and Drugged Driving Act

RA 10586

Traditional and Alternative Medicines Act

RA 8423

The label of the drug is false and misleading, hence, the product is:

Misbranded

Revised regulations for licensing of drug establishments and outlets

The prescription book shall be open at all times for inspection and shall be preserved for a period of at least how many months after the last entry

24 months

Dangerous drugs logbook

1 year

Prescription book

2 years

Poison logbook

5 years

The Professional Board of Pharmacy is appointed by:

President of the Philippines

This contains information for non-prescription drugs used by the patient

Patient Information Leaflet

Classification of recall called for a situation in which use or exposure to a violative product may cause temporary or medically reversible adverse health consequences or where the probability of serious adverse health consequences is remote

Class 2 Recall

a situation in which there is a reasonable probability that the use or exposure to a violative product will cause serious adverse health consequences or death.

Class 1 recall

a situation in which the use or exposure to a violative product is not likely to cause adverse health consequences.

Class 3 recall

gastro

Hannah Angelique Losaria · 100問 · 2年前

gastro