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問題一覧
1
In the microbial assay of antibiotics, the microorganism used for pen g is?
s aureus
2
Bottles, vials, caps, packer boxes. Which is not a primary packaging component
packer boxes
3
Drug substances that are withheld from distribution until batch certification from FDA has been received
antibiotics
4
Content uniformity is to be performed for all tablets whose active ingredients are:
50mg or less
5
The presence of cotton fiber in a liquid preparation is considered as an/an
ocular defect
6
In infrared spectrometry, water is not used as solvent because water will:
absorb IR radiation, dissolve the NaCl cell holder
7
The law related to spectrometry wherein the power of transmitted light decreases exponentially as the THICKNESS of the solution INCREASES ARITHMETICALLY is:
lambert's/ bouger's
8
The power of transmitted radiant beam DECREASES exponentially as the CONCENTRATION of the solution containing the absorption species increases arithmetically
beer's
9
In the spectrophotometry procedure for assay, aside from the sample of unknown, this is also required
reference
10
Formation of gas, formation of precipitate, formation of soluble products, formation of slightly ionized substances. Which condition DOES NOT cause a reaction to go to completion?
formation of soluble products
11
A plot of absorbance against CONCENTRATION of a standard drawn in a straight line is
beer's
12
The indicator used in the assay of a weak acid reactung with a strong base is
phenolphthalein TS
13
Strong acid, strong base indicator
phenolphthalein
14
Strong acid, weak base indicator
methyl red
15
Strong base, weak acid indicator
phenolphthalein
16
Weak acid, weak base indicator
none
17
The method of assay of vitamin b12 and calcium pantothenate is
microbial-turbidimetric method
18
Measure of excess energy loss by emission
fluorometry
19
Example of fluorometry
thiamine, riboflavin
20
Measure of TRANSMITTED light
turbidity
21
Example of turbidity
antibiotics, ca pantothenate, vit b12
22
Measure REFLECTED light
nephelometry
23
An excellent solvent for fats and fatty oils used in the determination of extractive content of a plant sample
water
24
Temperature equivalent to dull red heat
800-1000°c
25
Addition of an excess titrant to permit complete reaction of the analyte with the titrant and then titrating the unreacted excess titrant with another standard solution
residual titration
26
Analyte is reacted with titrant after rendering it soluble in the titration medium
direct titration
27
Analyte undergoes preliminary treatment prior to titration
indirect titration
28
Appropriate solvent for extraction of RESINS
ethanol
29
It is a property of liquids tgat is closely related to the RESISTANCE TO FLOW
viscosity
30
This raw material quality control test entails addition of silver nitrate to a hydrochloric acid standard
limit test for chlorides
31
This raw material quality control test entails addition of barium chloride to a sulfuric axid standard
limit test for sulfates
32
Passage of a fluid or solution through a sterilizing grade membrane to produce a sterile effluent
sterilization by filtration
33
Paddle over disk is also known as
apparatus 5
34
Basket is apparatus number
1
35
Paddle is apparatus number
2
36
Reciprocating cylinder is also known as apparatus number
3
37
Flow through cell is apparatus numer
4
38
Revolving cylinder is apparatus number
6
39
Reciprocating holder is apparatus number
7
40
Buccal tablets should disintegrate within
4 hours
41
The radiant energy requiredin the analysis of drugs using fluorometry
IR
42
Immediate release tablets/capsules
within 30 mins in water
43
Buccal tablets
within 4 hours in water
44
Sublingual tablets
2-3 minutes in water
45
Enteric coated in water
5 mins
46
Enteric coated in gastric fluid
1 hour
47
Usp method 1 for iodine value
hanus
48
Hanus
12 and br2
49
Method 2 in iodine value
wijs
50
Wijs
12 monochloride
51
Method 3
hubl
52
Hubl
unofficial method
53
The operating speed for paddle in dissolution apparatus is
50rpm
54
Content uniformity test used to ensure which of the following quality in tablet products
potency
55
Class if raw materials, which are to be subjected in tests and assays by the qc department and are still WAITING the final disposition of the qc department
quarantined products
56
The theoritical point at which equivalent amounts of analyte and titrant have reacted us called
stochiometric/ equivalence point
57
Buret, pipet, grad. cylinder, vokumetric flask. Which is the LEAST accurate
pipet
58
High efficiency particulate air (hepa) is an example of
filter
59
Endpoint assay of SODIUM NITRATE
light pink
60
Far IR
15-300
61
Medium IR
3-15
62
Near IR
780-3000
63
Visible IR
380-780
64
UV
200-380
65
Section of qc responsible for validating existing and tentative procedures of testing
specifications and analytical lab