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>0.5 mcm •visible in both ordinary and electric microscope •does not PASS THROUGH eg: enulsions, suspensions
coarse dispersion
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•Is the science of the delivery of APIs to the target site to achieve the pharmacological effect. •The study of the physical and chemical of drugs and their dosage forms. •Application of physics and chemistry in the study of drugs.
physical pharmacy
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Transfer of electrons
non metal, metal
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debye dipole- induced dipole
induction effect
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0.1 nm •visible only in ELECTRIC microscope •pass thru filter paper eg: cheese, butter
colloidal dispersion
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states that the total pressure in a mixture of gases is equal to the sum of the partial pressure of each gas
dalton's law of partial pressure
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characteristics of molecules that form mesophase
rigid, organic, possess strong dipole, depolarizable, elongated and redilinear shape
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NM + NM
covalent
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•follows the shape of its container •definite volume •gliding motion
liquid
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solubility of ionic crystals in water
ion-dipole
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describes the relationship between vapor pressure. and the absolute temperature of a liquid
clausius clapeyron equation
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this law states that the rate of diffusion of the gas and the speed of the gas molecules. are inversely proportional to the diffusion and effusion
graham's law
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independent of the amount of the substance in the system •temperature •pressure •density, SG, VG •viscosity •surface tension *unchanged
intensive
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<0.1 nm •INVISIBLE •pass thru filter paper amd semi permeable membrabe
true solution/molecular dispersion
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other term for mesophase
liquid crystalline state
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•thread like •rotate in 1 axis •mobile in 3 directions
nematic
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•constant P •ISOBARIC •Linear
charle's law
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weak forces that involves the dispersion of charge across a molecule called a dipole
Van der Waals forces
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other gas law
dalton's law of partial pressure, graham's law
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heat absorbed by 1 mole of liquid when it passes into vapor state
molar heat of vaporization
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exhibits properties intermediate between solids and liquids
mesophase
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only visible gas
nitrous oxide
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physical properties of system
intensive, extensive
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unequal sharing of electrons
polar
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a mixture of two or more components that form a honogenous molecular dispersion or one ohase system
solution
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most common gas laws
boyle's law, gay lussac's law, charle's law, combined gas law
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molecules or ions dispersed throughout the solvent
solute
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pressure of the saturated vapor above a liquid resulting from the escape of the surface liquid molecules
vapor pressure
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•special case •chiral nematic •higher opacity
cholesteric
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•mariotte's law • constant T •ISOTHERMIC •non linear
boyle's law
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van der waals forces
keesom, debye, london
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DEPENDENT of the amount of tye substances in the system •mass •length •volume *changed
extensive
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•important in biological structures •ex.: mi celles and lipid bilayer membrane
hydrophobic interactions
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london induced dipole-induced dipole
dispersion effect
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clad
cohesive like molecules adhesive different molecules
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types of mesophase
smectic, nematic, cholesteric
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other physical properties
additive, colligative, constitutive, density, SV, SG, MV
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forces necessary to cohere and forces necessary to prevent molecular interpenetration "clad"
repulsive or attractive
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resposible for the LIQUEFACTION OF GASES is an aerosolized dosage form. •brings about condensation of non polar gas molecules
london
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equal sharing of electrons
non polar
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results from the tendency of molecules to align themselves with the oppositely charged end of their neighbor
keesom
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keesom dipole-dipole
orientation effect
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aloy formation
metal, metal
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soap like or grease like •rotate in 1 axis •mobile in 2 directions
smectic
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•amonton's law •constant v •ISOCHORIC •linear
gay lussac's law
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polar molecules can produce temporary electric dipole in a non polar molecule
debye
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formation of iodide complex which accounts for solubility of iodine in Kl. test solution
ion-induced dipole
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uniquely strong hydrogen + fons accounts for the UNUSUAL PROPERTIES of water •high dielectric constant •high boiling point •low vapor pressure
hydrogen bonding
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the first recorded type of liquid crystal obtained through the application of heat
cholesteryl benzoate
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states that solubility of any gas increases as the external pressure is increased
henry's law
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classification of dispersed system
true solution/molecular dispersion, colloidal dispersion, coarse dispersion
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•fills available spaces •compressible •invisible •kinetic energy in rapid motion •weakest intermolecular forces
gas
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non metal + metal
ionic
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M + M
metallic