問題一覧
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An agent intended for use in the diagnosis, treatment, cure, mitigation, & prevention of disease in man or animals
DRUG
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Agents intended to be placed in contact with external parts of the human body, teeth, or mucus membranes
COSMETICS
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• AKA additives, adjuncts, pharmaceutical necessities • Largest percentage present in dosage form
EXCIPIENTS
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Reddens the skin
RUBEFACIENT
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Causes the contraction of body tissues to stop bleeding
ASTRINGENT
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Relieves itching
ANTI-PRURITIC
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Produces a superficial irritation in one part of the body to relieve irritation in another
COUNTER-IRRITANT
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Makes skin soft & pliable
EMOLLIENT
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Prevents the escape of water from the skin
OCCLUSIVE
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Prevents drying of the dosage form
HUMECTANT
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Intended to be swallowed
ORAL POWDERS
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• Powder for cleaning teeth • Abrasive, anti-cariogenic
DENTRIFICE
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• Applied into body cavities • Dissolved in warm water • pH usually 3.5-5
DOUCHE
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• Introduced into body cavities by insufflator • CONS: Inaccurate dosing
INSUFFLATION
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Dropped into the skin by means of sifter-top containers
DUSTING POWDERS
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Administered with the aid of inhalers
AEROSOLS
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From coarsely powdered herbs
POULTICE
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• A process of particle size reduction
COMMINUTION OF POWDERS
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Method of producing finer drug particles under 10 micrometers
MICRONIZATION
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• Intended to both comminute & mix • Grinded using mortar & pestle
TRITURATION
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Solutions, suspension, ointments
Glass
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Soft aggregates, crystals
Porcelain
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Crystalline solids
Wedgewood
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• Use of a non-volatile non-solvent • Forms a PASTE using a levigating agent • Ex. Mineral oil, glycerin
LEVIGATION
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• Addition of a volatile solvent • For gummy materials • Ex. Alcohol + camphor, Ether + iodine pellets
PULVERIZATION BY INTERVENTION
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• For non-potent substances • Results in a light, fluffy product
SIFTING
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• For small amounts of powders & non-potent substances • Eutectic mixtures
SPATULATION
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• For potent substances • 1:1 proportion
GEOMETRIC DILUTION
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Mixing in a large, rotating chamber
TUMBLING
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Prepared agglomerates of smaller particles of powder
GRANULES
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Removed prior to use
RELEASE LINER
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Ensures contact for continuous drug release
adhesive layer
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where the drug is kept
drug reservoir
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release controller
microposous membrane
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protects the patch from the environment prevents drug/ water loss
occlusive backing layer
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supersonic shock waves of helium gas
high velocity powder particles
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low voltage curent to fascilitate diffusion
iontophoresis
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shirt high-volatage electric pulses which creates acqueaous phores
electrophoration
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higgh frequency ultrasound
sonophoresis
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homogenous blend of PEGs and polysorbate 80
polybase
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aka pluronics black copolymers
poloxamers
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70% glycerin 20% granular gelatin 10%Drug
glycenerated gelatin
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bn: carbowax polymers of ethylene oxide and water
peg
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eutectic mixture of mono-di, triglycerides derived from natural vegetable oils
suppocire
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triglycerides from palm, palm kernel, coconut oils
fattibase
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daturated fatty acid esp lauric acid
witepsol
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coconut oil
wecobee
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most stable form: beta
cocoa butter
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small, compressed or tuft
pledget
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plastic masses used in dermatological practice
dressing
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soft moist mass in hot cloth
cataplasm
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dental fillings
cements
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uses muslin cloth
cerates
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• AKA: Water-ABSORBABLE • Do not contain oleaginous → greaseless • For incorporation of solids
water soluble
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• AKA: Water-MISCIBLE • o/w emulsions resembling creams • Absorbs serous discharges
water removable
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• Greasy & non-water washable • Absorbs small amounts of water
absorption
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• AKA: Hydrocarbon base • Emollient, occlusive dressing
oleaginous
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holds the valve in place
mounting cup
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delivers and regulates the flow of material from the container
valve
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prevents formulation leakage
gsket
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holds gasket in place
spring
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brings formulation from conntainer to valve
dip tube
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links the dip tube, stem, actuator
housing
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supports actuator
stem
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button pressed to activate valve assembly
actuator
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expasion of propellant- small bubbles
foam
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carry API to srface
surface
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remains in the air for prolonged periods
space
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• O/W → W/O • W/O → O/W
phase inversion
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irrecersible separation of the internal phase
cracking/ breaking
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complete fusion
coalescence
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reversible agglomeration
flocculation
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downward movement w/o
sedimenttaion
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ipwad movement o/w
creaming
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in situ soap 1:1
nascent
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forbes 3:2:1 for volatile oils
bottle
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english 4:2:1 water, gum, oil drop by drop
wet gum
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continental 4:2;1 oil, gum, water all at once
dry gum
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Plastic masses containing 15% gelatin, 40% glycerin, 30% water, & 10% API
glycerogelatins
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Aqueous suspensions of insoluble inorganics having bigger particles than gels & lotions
magmas
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Liquid suspension or dispersion with LOW viscosity intended for external application to the skin
lotions
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irreversible sol-gel formation
rheopexy
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reversible gel-sol formation
thixotropy
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liberatiion of oil/water
bleeding
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liquid is removed andonly framework remains
xerogel
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gel shrinks with loss of liquid
syneresis
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take ip liquid with increase in vlume
syneresis
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take up liquid without increase in volume
imbibtion
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Clear, sweetened hydroalcoholic solutions intended for oral use & are usually flavored to enhance their palatability & always contains alcohol
elixir
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injected into bloodstream
parenteral
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Sterile, non-pyrogenic solutions used to wash or bath surgical incisions, wound or body tissue.
wound irrigation
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Alcohol or oil-based solutions prepared from vegetable materials or from chemical substances. • 10% Potent
tinctures
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Occlusive, protectant, applied over bandages
collodion
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Class of gels with a structural matrix containing a higher percentage of water
jellies
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Thick, viscid adhesive liquids made of dispersing gum in water
MUCILAGE
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Thick liquid preparations allied to syrups but used as base
HONEY
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Viscous oral liquid that generally contains a higher concentration of sugar
LINCTUS
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Concentrated aqueous preparation of sugar or sugarsubstituted w/ or w/o flavoring agents & medicinal substances & may contain alcohol as preservative or as solvent for the flavors but not as the general solvent • SIMPLE SYRUP: 85% w/v or 65% w/w
SYRUP
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Treatment of the pharynx & nasopharynx by forcing air from the lungs thru the gargle, held in throat & spit out.
.GARGLE
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Used by swishing the liquid in the oral cavity
MOUTHWASH