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問題一覧
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-application of physical and chemical principles and laws in pharmaceutical scoences -physical chemistry in pharmacy -to understand and develop dosage forms and drug delivery system
physical pharmacy
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indivisible unit of matter
atom
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combination of atoms
molecule
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combination of DIFFERENT atoms
compound
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cation or anion
ions
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forces within a molecule
intramolecular forces
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ionic bonding
transfer of electron
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covalent bonding
sharing of electron
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intermolecular forces
forces between a molecule
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transfer of electron
ionic
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electronegativity difference of ionic
>1.7
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unequal sharing of electrons
polar covalent
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electronegativity difference of polar covalent bond
0.5-1.7
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equal sharing of electron
non polar covalent bond
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electronegativity difference of non polar covalent bond
<0.5
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alloy formation between 2 or more metals goal: resistanc to corrosion
metallic bond
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polar molecules attracted to either positive or negative charges
ion dipole
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the force of attraction induced by a close proximity of a charged ion into a non-polar molecule
ion-induced dipole
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attraction of H for a strongly elctronegative ion
hydrogen bonds
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depends on the sum of the individual properties of the components present in a system
additive property
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depends on the type and arrangement of the components present in the system
constitutive property
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depends on the number of components present in a system
colligative property
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depends on the size or amount of material in the sytem eg: V, entropy, enthalpy, electric resistence, mass
extensive
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does not depend on the size or the amount of material in the system eg: Sp gravity, viscosity, velocity
intensive
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numerical value of density
specifc gravity
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meausure of the disorder or randomness of a system
entropy
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sum of internal energy E of a system and the poduct of the pressure and volume of the system
enthalpy
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AKA mesophase, liquid crystal -partly solid and partly liquid -tends to flow like liquid under extreme conditions
plasma
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the property of plasma to divide the passing light into two components with differeent velocities and refractive index
birefringence
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soap like/grease like, rotates in one axis, mobile on 2 directions -most important pharmaceutical setting
smectic
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thread like, rotates in one axis, mobile in 3 directions
nematic
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considered as special type of nematic, with highest opacity (chiral nematic)
cholesteric
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first plasma produced by thermotropic method
cholesteryl benzoate
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only visible gas
nitrogen oxide