glucocorticoids

blocks 5ht3 receptor in the affarebt neurons distention induced sensory and motor reflex activation colonic motility

5ht4 agonist enteric neurons acetylcholine release 5ht3 antagonist

tx for crohn's disease

directly stimulates motilin receptor onset of migrating motor complex

sorbitol

resident bacteria cleanse the azo bonds by means of

resembles serotonin in structure

example of stool surfactants

reduce ammonia levels in hepatic encephalopathy

prototypic muscarinic receptor antagonist most effective for motion sickness

reduces absorption of the oarent drug from the small intestine

tx for IBS with predominant constipation

acetylcholinisterase inhibitor, ohilvie's syndrome

SE of somatostatin and ocreotide

inhibits the secretion of gastrin, cholecystokinin, glucagon, growth hormone, insulin secretion, pancreatic polypeptide, vasoactive intestinal peptide, and 5ht3

parkinsonism syndrome, restlessness

gi transit, speed gastric emptying time

softeners

perirectal fistulas, fissures abscesses, anal stenosis

tx of chemo induced vomiting

potent antiemetics. blocks d2 receptor in ctz antagonize amorphin induced vomiting

hydrolyzed in small intestine local irritant that stimulates inyestinal motility

cholinomimetic agents

synthetic fibers

prokinetic indications

methomoglobinemia

adr of serotonin 5htr receptor antagonist

aloe, senna, cascara

SE of bile salt resins

contains time release microgranules

do not give to pc with crohns diseas, obstruction, intestinal strictures

side effects of anthraquinone derivatives

before the initiation of cemotherapy to reduce anticipatory vomiting

antipsychotic agents potent antiemetic and sedative properties inhibits dopamine and muscarinic antihistamine

dioperidol

diphenylmethane derivatives

mouth to anus; rectum is spared

examples of bile salt resins

cannot be given to patients with bloody diarrhea, fever, and systemic toxicity

immune mediated chronic intestinal condition

hyosyamine

blocks dopamine d2 receptor, anti nausea, antiemetic. includes prolactin, cholinergic smooth muscle stimulation

inhibits muscarinic cholinergic receptor in the enteric plexus; smooth muscles

tx of constipations

soften stool materials, permits h2o and lipides to penetrate

anti emetic due to dopaminergic blockade metoclopramide and trimethobenzamide dopamine receptor blockade

major psychoactive compound

dexamethasone, methylprednisolone

laxatives

mainstay of therapy for mild to moderate ulcerative colitis

delivered at high concentration to the rectum and the sigmoid colon

involves the rectum, extends proximally to involve the colon

side effect of mesalamin compounds

magnesium oxide

mesalamine compounds

purgatives

motion sickness, lesser morning sickness anti emetic properties is base on anti cholinergic, anti histamine and sedation

prophylaxis of motion sickness clear for tetranogenic potential

h2 antihistamines

soluble but not absorbable compound. results to increase stool liquidation

cardiac arrythmias

lorazepam and diazepam

substituted benzamines

bound to 4-aminobenzoyl-b-alanine secretory diarrhea

oated in ph-sensitive resinthat dissolves at ph7

5 asa group are bound together

complete colonic cleansing before git endoscopy

dulcolax

backwash ileitis

tx of fecal impaction and debilitated adults

natural plant producs

induction and maintenance of remission of UC and CD post operative prophylaxis of cd

diarrhea caused by excess bile acids, crohn's disease and resection of terminal ileum

half life of somatostatin

examples of antispasmodics

carceroid and VIPoma

difficult or infrequent passage of stools

inhibition of endocrine tumor

fat-soulble vitamins

induce bowel movements through direct stimulation of enteric ns, colonic electrolyte, fluid secretion

rectal burning

clear, viscous oil that lubricates fecal material

side effects of mineral oil

dronabinol

IBD

appetite stimulant

half life of ocreotides

mild to moderate acute diarrhea control diarrhea caused by IBS and IBD

acute colonic pseudoobstruction

not to be given in px with hpn, chf, and renal impairment

muscarinic m3 receptor on myenteric plexus synapse

qt interval prolongation, cardiact arrest, sudden death

indigestible, hydrophillic colloids that absorbs water forming or bulky emollient gels

phased out in market due to cardiac toxicity

dicyclomine

examples of azo compounds

example of antidiarrheal

purine anti metabolite

diarrhea predominant ibs