問題一覧
1
True nonsedating antihistamines
loratadine, disloratadine, fexofenadine
2
Antidiuretic action in individuals with mild or moderate diabetes insipidus
fenofibrate
3
Congenital heart defect where one of the heart valves is malformed
ebstein anomaly
4
The skin condition exhibits a distinct net like pattern of reddish blue discoloration
livedo reticularis
5
Inflammatory condition involving eosonophiles. Ld4 related
eosinophilic vasculitis
6
Characterized by severe asthma and eosinophilic vasculitis. Ld4 related
churg strauss syndrome
7
Ltd4 receptor antagonist
montelukast, zafirlukast, pranlukast
8
Stimulant laxative that cause melanosis coli
senna
9
Cefotetan is cobtraindicated to
alcoholic patients
10
For acute gputy attacks, anti mitotic
colchicine
11
Diuretic used for patients with traumatic head injury and cerebral edema
mannitol
12
Primary mechanism of ne release is accompanied by this process
exocytosis
13
K+ competers with digoxin in the na/k atpase pump
hypokalemia
14
Low mg leads to high ca that leads to inotropy
hypomagnasemia
15
Low o2= high hr
hypoxia
16
Too much inotropy
hypercalcemia
17
Antiemetic drug that is a synthetic form of tch used for nausea and vomiting associated with chemotherapy
dronabinol
18
Anfi emetic that acts as a dopamine receptor antagonist and increases the tone of the lower esophageal spincter, which helps prevent reflux and vomiting
metoclopramide
19
Anti emitic that is neurokinin 1 receptor antagonist
aprepitant
20
Reversible adp inhibitors
ticagrelor, cangrelor
21
First generation sulfonylureas
chlorpropamide, tolbutamide, tolazamide, acetazolamide
22
First gen sulfonylurea with the longest half life
chlorpropamide
23
Toxic effect of chlorpropamide
hepatic or renal insufficiency
24
Shortest half life first gen sulfonylurea
tolbutamide
25
Toxic effect of tolbutamide
cardiotoxicity
26
Non selective beta blockers are contraindicated to patients with
asthma or copd
27
Non selective beta blockers
nadolol, sotalol, timolol, propanolol, pindolol
28
Cardioselctive b blockers
canbeam
29
With charge Polar Dissolves more rapidly Easily excreted
ionized salt form
30
No charge Lipid soluble Easily absorbed
non ionized
31
Hypourecimic agent that inhibits xanthine oxidase for gout
allopurinol, febuxostat
32
Noyes whitney
dissolution
33
Ficks law
diffusion
34
Arrhenius
stability or shelf life
35
Henderson hasselbalch
buffers
36
Neurotransmitter primarily responsible for the transmission in the sympathetic ns
ne
37
Androgens and sex hormones
zona reticularis
38
Glucocorticoids, cortisol
zona fasciculata
39
Minercorticoids, aldosterone
zona glomerulosa
40
Aka inactivation antagonism, chemical reaction between compounds
chemical antagonism
41
Aka physiologic antagonism, different receptors, opposing effect
functional antagonism
42
Aka receptor antagonism, same receptor, different effects
pharmacological antagonism
43
Tranexamic acid inhibits
plasminogen activation
44
Escilatopram is classified as
ssri
45
Se of diazoxide
hyperglycemia
46
Vasodilators that is used as alternative for hypertensive crisis
diazoxide
47
Fibrinolytics
streptokinase, anisylated plasminogen, recombinant tpa, urokinase
48
Antiplatelet that is txa synthesis inhibitor
aspirin
49
Apetitle stimulant
dexamethasone, dronabinol, magestral oxandrolone
50
Anorexiant
methamphetamine, phendimetrazine, dexamethasone
51
Diuretic for altitude sickness
acetazolamide
52
Diuretic for patients having hyoercalcemia manifestation
furosemide
53
Diuretic effective in preventing calcium stone
chlorthalidone
54
Decrease hepatic gluconeogenesis Stimukates amino acid uptake into cells Increase glucose uptake of cells Induction of glycogen synthesis
insulin
55
Chlordiazepoxide is a
benzodiazepine
56
Chlorthalidone is a
thiazide diuretic
57
Chlorpromazine is a
antipsychotic
58
Symbicort
budesonide, formoterol
59
Seretide
salmeterol, fluticasone
60
Bupropion is
atypical antidepressant
61
Pagets disease, osteoporosis
alendronate
62
Pro aggregants
thromboxane, adp, serotonin
63
Anti aggregants
camp, pge, pgi2
64
Newly discovered cox1 variation but still not well established
cox3
65
B blocker with membrane stabilizing activity
propanolol, pindolol, labetalol, metoprolol, acebutolol
66
Doc for parkinsons
levodopa, carvidopa
67
Dopamine release Used for parkinsons disease
amantadine
68
Comt inhibitor Parkinson's disease
tolcapone
69
Mao b inhibitor Parkinson's disease
seligiline
70
Insulin is secreted by
pancreatic beta cells
71
Thiothexene is
thioxanthine
72
Same with rickets
osteomalacia
73
Vit d deficiency that leads to soft bones
rickets
74
Calcium sensitizer; increase the sensitivity of the troponin system in heart muscle cells to calcium
levosimendan
75
Phosphodiesterase inhibitor, increase levels of camp in heart muscles
milirinone
76
Natriuretic peptide that acts as vasodilator, used for hf
nesiritide
77
Drug for hf that is currently investigational
istaroxime
78
Drugs used in management of hypertension
diuretics, alpha 2 agonists, ace inhibitors
79
Refers to lipid solubility/water solubility
k partition