問題一覧
1
Volatile metals
zn, cd, hg
2
Coinage metas
cu, ag, au
3
Causes glossitis
gold
4
Causes bronze like skin "Wilson's disease"
copper
5
Causes baritosis
barium
6
Lightest metal
lithium
7
Aqua fortis
nitric acid
8
Heavy water
d2o
9
Acts in 30s ribosomal subunits
aminoglycosides, tetracyclines
10
Acts on 50s ribosomal subunits
chloramphenicol, erythromycin (macrolides), lincosamides
11
Molds
methylparaben
12
Yeast
propylparaben
13
Selection of structure components. The steric, electronic, and solubility characteristics of a drug which makes it interchangeable with drugs of the same pharmacologic class
isosterism
14
More than one compound have the same chemical formula but different chemical structures
isomerism
15
Relates the structure of the drug to its MOA or biological effects
SAR
16
The property of two dosage forms or active ingredients with similar blood concentration levels that produce the same effect at the site of physiological activity
bioequivalence
17
The cell will no longer divide
g0
18
Cells increased in the size and produces enzyme for dna synthesis *No replication occur and cells only grow larger
g1
19
Dna synthesis and replication occur
s
20
Gap between s phase and mitosis wherein the cell will continue to grow and produce new proteins and RNA
g2
21
Cell divides into two daughter cells
m (mitosis)
22
Only IV insulin
regular insulin
23
Intermediate acting insulin
isophane
24
"humalog" rapid acting insulin
lispro
25
Long acting insulin
degludec
26
Anticancer agents derived from the bark of pacific yew that stabilizes microtubules and inhibits depolymerization
taxanes
27
Derived from periwinkle that inhibits tubulin polymerization and microtubule formation
vinca alkaloids
28
Derived from mayapple root that inhibits topoisomerase 2
epipodophyllatoxins
29
Inhibits topoisomerase l ( topotecan, irinotecan)
camptothecin derivatives
30
Other term for first dose effect
syncope/ orthostatic hypotension
31
A common side effect involved with alpha 1 blockers and vasodilation
first dose effect
32
Fluoroquinolones under first generation
norfloxacin
33
Fluoroquinolones under 2nd generation
ciprofloxacin, ofloxacin
34
Fluoroquinolones under 3rd generation
levofloxacin, gemifloxacin, moxifloxacin
35
DOC for schistosomiasis
praziquantel
36
DOC wuchereria bancrofti
DEC
37
Alternative TC for taenia spp.
niclosamide
38
Onchocerca vovulus and strongyloides stercoralis
ivermectin
39
Dihydropeptoate synthase inhibitor
sulfamethoxazole
40
Inhibits renewal dihydropeptase
cilastatin
41
Inhibits beta lactamase
sulbactam
42
Inhibits folate reductase
trimethoprim