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  • Hannah Angelique Losaria

  • 問題数 100 • 10/5/2024

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    問題一覧

  • 1

    Specific cox 2 inhibitor withdrawn to the market due to stroke and heart attack

    rofecoxib, valdecoxib

  • 2

    Gastrokinetic 5-HT4 agonist withdrawn to the market due to arrhythmia

    cisapride

  • 3

    -metabolized to paracetamol -withdrawn to the market due to nepropathy, carcinogen

    phenacetin

  • 4

    Biguanide; withdrawn due to lactic acidosis

    phenformin

  • 5

    Dopamine agonist( Parkinson's disease) -withdrawn due to vulvular heart disease

    pergolide

  • 6

    Doc for migraine that is a full lB/lD serotonin receptor agonist

    triptans

  • 7

    Doc for migraine that is a vasoselective alkaloid often used in combination with caffeine

    ergotamine

  • 8

    Doc for migraine that is a uterselective ergot alkaloid

    ergonovine

  • 9

    Migraine prophylaxis that is a serotonin antagonist

    methysergide

  • 10

    Tetrodotoxin acts on which channel?

    calcium channel

  • 11

    Oldest broad spectrum antibiotic

    chloramphenicol

  • 12

    Medication for alcohol addiction that causes hangover like effect

    disulfiram

  • 13

    Bioavailability that has 100% efficacy

    intracardiac, intraarterial, intravenous

  • 14

    Acetylated morphin

    heroin

  • 15

    Methylated morphine

    codeine

  • 16

    For chronic gout

    colchicine

  • 17

    (+) uric acid urinary secretion for chronic gout

    probenacid

  • 18

    Purine xanthine oxidase inhibitor used for chronic gout

    allopurinol

  • 19

    Non purine xanthine oxidase inhibitor used for chronic gout

    febuxostat

  • 20

    Cox enzyme that is normally present, protects gastric mucosa, positive platelet aggregation "Housekeeping cox"

    cox1

  • 21

    Cox inhibitor that is inducible during injury, causes inflammation

    cox2

  • 22

    Cox enzyme known for the production of headaches

    cox3

  • 23

    Nsaid that is required to add a black box warning on its label due to increased risk of thrombosis and stroke

    rofecoxib

  • 24

    Nsaid that is the first line for stroke treatment and prevention

    aspirin

  • 25

    Nsaid used for closure of patent ductus arteriosus

    indomethacin

  • 26

    "preferentially selective cox ll inhibitor" nsaid

    meloxicam

  • 27

    Element used in rheumatoid arthritis

    gold

  • 28

    Usec for tensilon test

    endrophonium

  • 29

    Most potent h2 receptor antagonist

    famotidine

  • 30

    Factors targeted by warfarin

    10972

  • 31

    High ceiling diuretics

    loop diuretics

  • 32

    SE of ace inhibitors

    dry cough

  • 33

    Most effective in increasing hdl levels

    niacin

  • 34

    Contains the highest concentration and greatest number of prostaglandins

    seminal fluid

  • 35

    Doc for partial seizure, tic duoloureux ( trigeminal neuralgia)

    carbamazepine

  • 36

    Doc for grand mal seizure

    valproic acid

  • 37

    Petit mal/ absence seizure

    ethosuximide

  • 38

    Doc for neonatal seizure

    phenobarbital

  • 39

    Doc for catemenial seizure

    acetazolamide

  • 40

    Heparin monitoring

    appt

  • 41

    Warfaring monitoring

    pt inr

  • 42

    Doc for febrile seizures

    phenobarbital

  • 43

    Doc for status epilepticus

    lorazepam

  • 44

    Most abundant cyp hormones

    cyp3a4

  • 45

    Most important organ for absorption

    small intestine

  • 46

    Dissociative anesthetic sold as angel dust

    ketamine

  • 47

    Weakest anesthetic

    nitrous oxide

  • 48

    Anesthetic preferred for children

    sevoflurane

  • 49

    Anesthetics preferred for asthmatics

    enflurane

  • 50

    Most hepatotoxic anesthetic

    halothane

  • 51

    Anesthetic of choice for labor

    methoxyflurane

  • 52

    For vertigo

    betahistine

  • 53

    Dolor

    pain

  • 54

    Calor

    heat

  • 55

    Rubor

    redness

  • 56

    Tumor

    swelling

  • 57

    Functio laesa

    loss of function

  • 58

    Decreased ne, decreased gaba, decreased serotonin

    anxiety

  • 59

    Increased da

    schizophrenia

  • 60

    Decreased acetylcholine

    alzeimers

  • 61

    Decreased ne, decreased serotonin

    depression

  • 62

    Decreased da

    parkinsons

  • 63

    Inhaled corticosteroids

    fluticasone, budesonide

  • 64

    Short acting agents, for acute conditions

    relievers

  • 65

    Long acting agents, for maintenance

    controllers

  • 66

    B blocker used for stagr fright

    propranolol

  • 67

    Should not be given approximately prior niacin to avoid flushing reaction

    aspirin

  • 68

    Alpha2

    inhibits lipolysis

  • 69

    Barbiturates used for induction of anesthesia

    ultra short acting

  • 70

    Barbiturates used in sedation

    short acting

  • 71

    Barbiturates used in hypnotics

    intermediate acting

  • 72

    Barbiturates used as anti convulsant

    long acting

  • 73

    Beta 3

    stimulates lipolysis

  • 74

    Antipsychotic with severe eps

    haloperidol

  • 75

    Antipsychotic associated with sedation and constipation

    quetiapine

  • 76

    Antipsychotic associated with corneal deposit with no blindness

    chlorpromazine

  • 77

    Antipsychotic associated with retinal deposit with blindness

    thioridazine

  • 78

    Antidote for methane

    mineral oil

  • 79

    Excessive sneezing

    sternutator

  • 80

    Increase flow of tears

    lacrimator

  • 81

    Causes unconsciousness or death by suffocation

    asphyxiant

  • 82

    A substance that act locally on cutaneous or mucosal surface and illicits an inflammatory response

    irritant

  • 83

    Refers to the percentage of if the administered dose of a drug that reaches the systemic circulation in its unchanged form; refers to both rate and extent of if absorption

    absolute bioavailability

  • 84

    Compares to the bioavailability of a drug product to a reference standard product

    relative bioavailability

  • 85

    Measurement used to quantify the total amount of drug absorbed into the bloodstream overtime

    auc

  • 86

    Protein drugs that remains in the ststemic circulation for storage/ reservoir

    protein bound drugs

  • 87

    Protein drugs that undergoes metabolism, goes to target organs, and passes and crosses membrane bound organs

    protein unbound drugs

  • 88

    Autacoids

    bradykinin, serotonin, eicosanoids, histamine

  • 89

    Cholinergic nt

    acetylcholine

  • 90

    Adrenergic nt

    ne, epi, dopa

  • 91

    2nd line for stroke prevention

    clopidogrel, cilostazol

  • 92

    Tamoxifen is used for

    breast cancer

  • 93

    Ability of a drug to bind to its receptor

    affinity

  • 94

    The rate at which the drug leaves the body

    elimination rate

  • 95

    Time it takes for a drig to exert its effects

    onset of action

  • 96

    Bangkok pills that is known for being an anorexiant

    phentermine

  • 97

    Alternative for hypertensive crisis known to cause hirsutism

    minoxidil

  • 98

    Only nsaid that is a weak acid (ketone)

    nabumetone

  • 99

    Receptor that inhibits adenyl cyclase

    gi