問題一覧
1
Specific cox 2 inhibitor withdrawn to the market due to stroke and heart attack
rofecoxib, valdecoxib
2
Gastrokinetic 5-HT4 agonist withdrawn to the market due to arrhythmia
cisapride
3
-metabolized to paracetamol -withdrawn to the market due to nepropathy, carcinogen
phenacetin
4
Biguanide; withdrawn due to lactic acidosis
phenformin
5
Dopamine agonist( Parkinson's disease) -withdrawn due to vulvular heart disease
pergolide
6
Doc for migraine that is a full lB/lD serotonin receptor agonist
triptans
7
Doc for migraine that is a vasoselective alkaloid often used in combination with caffeine
ergotamine
8
Doc for migraine that is a uterselective ergot alkaloid
ergonovine
9
Migraine prophylaxis that is a serotonin antagonist
methysergide
10
Tetrodotoxin acts on which channel?
calcium channel
11
Oldest broad spectrum antibiotic
chloramphenicol
12
Medication for alcohol addiction that causes hangover like effect
disulfiram
13
Bioavailability that has 100% efficacy
intracardiac, intraarterial, intravenous
14
Acetylated morphin
heroin
15
Methylated morphine
codeine
16
For chronic gout
colchicine
17
(+) uric acid urinary secretion for chronic gout
probenacid
18
Purine xanthine oxidase inhibitor used for chronic gout
allopurinol
19
Non purine xanthine oxidase inhibitor used for chronic gout
febuxostat
20
Cox enzyme that is normally present, protects gastric mucosa, positive platelet aggregation "Housekeeping cox"
cox1
21
Cox inhibitor that is inducible during injury, causes inflammation
cox2
22
Cox enzyme known for the production of headaches
cox3
23
Nsaid that is required to add a black box warning on its label due to increased risk of thrombosis and stroke
rofecoxib
24
Nsaid that is the first line for stroke treatment and prevention
aspirin
25
Nsaid used for closure of patent ductus arteriosus
indomethacin
26
"preferentially selective cox ll inhibitor" nsaid
meloxicam
27
Element used in rheumatoid arthritis
gold
28
Usec for tensilon test
endrophonium
29
Most potent h2 receptor antagonist
famotidine
30
Factors targeted by warfarin
10972
31
High ceiling diuretics
loop diuretics
32
SE of ace inhibitors
dry cough
33
Most effective in increasing hdl levels
niacin
34
Contains the highest concentration and greatest number of prostaglandins
seminal fluid
35
Doc for partial seizure, tic duoloureux ( trigeminal neuralgia)
carbamazepine
36
Doc for grand mal seizure
valproic acid
37
Petit mal/ absence seizure
ethosuximide
38
Doc for neonatal seizure
phenobarbital
39
Doc for catemenial seizure
acetazolamide
40
Heparin monitoring
appt
41
Warfaring monitoring
pt inr
42
Doc for febrile seizures
phenobarbital
43
Doc for status epilepticus
lorazepam
44
Most abundant cyp hormones
cyp3a4
45
Most important organ for absorption
small intestine
46
Dissociative anesthetic sold as angel dust
ketamine
47
Weakest anesthetic
nitrous oxide
48
Anesthetic preferred for children
sevoflurane
49
Anesthetics preferred for asthmatics
enflurane
50
Most hepatotoxic anesthetic
halothane
51
Anesthetic of choice for labor
methoxyflurane
52
For vertigo
betahistine
53
Dolor
pain
54
Calor
heat
55
Rubor
redness
56
Tumor
swelling
57
Functio laesa
loss of function
58
Decreased ne, decreased gaba, decreased serotonin
anxiety
59
Increased da
schizophrenia
60
Decreased acetylcholine
alzeimers
61
Decreased ne, decreased serotonin
depression
62
Decreased da
parkinsons
63
Inhaled corticosteroids
fluticasone, budesonide
64
Short acting agents, for acute conditions
relievers
65
Long acting agents, for maintenance
controllers
66
B blocker used for stagr fright
propranolol
67
Should not be given approximately prior niacin to avoid flushing reaction
aspirin
68
Alpha2
inhibits lipolysis
69
Barbiturates used for induction of anesthesia
ultra short acting
70
Barbiturates used in sedation
short acting
71
Barbiturates used in hypnotics
intermediate acting
72
Barbiturates used as anti convulsant
long acting
73
Beta 3
stimulates lipolysis
74
Antipsychotic with severe eps
haloperidol
75
Antipsychotic associated with sedation and constipation
quetiapine
76
Antipsychotic associated with corneal deposit with no blindness
chlorpromazine
77
Antipsychotic associated with retinal deposit with blindness
thioridazine
78
Antidote for methane
mineral oil
79
Excessive sneezing
sternutator
80
Increase flow of tears
lacrimator
81
Causes unconsciousness or death by suffocation
asphyxiant
82
A substance that act locally on cutaneous or mucosal surface and illicits an inflammatory response
irritant
83
Refers to the percentage of if the administered dose of a drug that reaches the systemic circulation in its unchanged form; refers to both rate and extent of if absorption
absolute bioavailability
84
Compares to the bioavailability of a drug product to a reference standard product
relative bioavailability
85
Measurement used to quantify the total amount of drug absorbed into the bloodstream overtime
auc
86
Protein drugs that remains in the ststemic circulation for storage/ reservoir
protein bound drugs
87
Protein drugs that undergoes metabolism, goes to target organs, and passes and crosses membrane bound organs
protein unbound drugs
88
Autacoids
bradykinin, serotonin, eicosanoids, histamine
89
Cholinergic nt
acetylcholine
90
Adrenergic nt
ne, epi, dopa
91
2nd line for stroke prevention
clopidogrel, cilostazol
92
Tamoxifen is used for
breast cancer
93
Ability of a drug to bind to its receptor
affinity
94
The rate at which the drug leaves the body
elimination rate
95
Time it takes for a drig to exert its effects
onset of action
96
Bangkok pills that is known for being an anorexiant
phentermine
97
Alternative for hypertensive crisis known to cause hirsutism
minoxidil
98
Only nsaid that is a weak acid (ketone)
nabumetone
99
Receptor that inhibits adenyl cyclase
gi