問題一覧
1
the following are the effects of alpha1 when activated, except
bronchodilation
2
the following beta blockers can be used for patients with asthma i metoprolol ii. bisoprolol iii. sotalol iv. atenolol
I, II, IV
3
the following antiarrhythmic agents targets potassium channel i. sotalol ii. disopyramide iii. dofetilide iv. veapamil
I, III
4
Historically, isoproterenol is a drug for asthma but is pulled out in the market because of?
arrhythmia
5
tetrodotoxin
puffer fish
6
cantharidin
blister fly/ spanish fly
7
clupeotoxin
oyster/ sardines
8
scromboid
mackerel/tuna
9
ciguatoxin
fish
10
the beta blockers that has mixed action in blocking alpha and beta receptor
carvedilol
11
snake toxin
hyaluronidase
12
black widow toxin
latrotoxin
13
bee toxin
apitoxin
14
the principal neurotransmitter involved in pns
acetylcholine
15
the DOC for chronic stable angina pectoris
b-blockers
16
the following are protein synthesis inhibitors, except
vancomycin
17
the following drugs can be used in treating HIV, except
ganciclovir
18
amantadine is indicated for the following, except
AOTA
19
the concept/ interaction involved beween heparin and protamine is
neutralization
20
the following are drugs for fungal infection, except
polymyxin
21
which of the following drugs does not belong
metacholine
22
excretion of salicylates and methotrexate can be done bby adding
NaHCO3
23
the following drugs are narrow therapeutic drug index, except
NOTA
24
the following drugs can be used to treat gestational HTN i. hyralazine ii. methyldopa iii. nifedipine iv. labetalol
AOTA
25
a drug that inhibits the vesicle mediated transport of dopamine
metyrosine
26
the most ototoxic loop diuretic
ethacrynic acid
27
the following are used as anticoagulant, except
dipyridamole
28
the following statin drug can be taken anytime of the day i. simvastatin ii. atorvastatin iii. rosuvastatin
i, iii
29
warfarin + cimetidine
increase pt-inr
30
a specific cardiac biomarker (gold standard) that is tested when a patient is diagnosed with MI
troponin
31
the following are the uses of aspirin i. antiplatelet ii. anti-inflammatory iii. analgesic iv. anti-pyretic
AOTA
32
the following are matabolim pathway of paracetamol,except
methylation
33
the following are effects of opioids, except
diarrhea
34
the following are effects of thoazide diuretics except
hypocalcemia
35
a class of antihypertensive that is contraindicated with patients taking non-dihydropyridines CCBs
b receptor blocker
36
this drug partially inhibits/blocks fatty acid oxidation in myocaardial cell, useful in cases of angina
trimetazedine
37
below are agents used in the treatment admanagement of heart failure, except
succinylcholine
38
what is the clnical application of drugs that inhibits dipeptidyl peptidase-4 a forbacterial infection
oral hypoglycemic
39
mechanism of granisetron
5HT3 receptor antagonist
40
agent of choice for the treatment of hyperthyroidism in women
PTU
41
hormones deficient in diabetes
vasopressin
42
the only non- acidic nsaid that resembles naproxen in strucure
nabumetone
43
this is a LOX inhibitor
zileuton
44
prostaglandin analog used for induction of labor
latanoprost
45
drug used in breast cancer patient who become resistant to tamoxifen
fulvestrant
46
rhinitis medicamentosa is associated with
A1 selective agonist
47
the following inhibits the synthesis of leukotriene, except
aminophylline
48
antipsychotic agent that doesn't produce a weight gain as a side effect
molindone
49
TB medication that causes hepatoxicity and hyperuricemia
pyrazinamide
50
the following belongs to ureido penicillins except i. ticarcillin ii. piperacilllin iii. methicillin
i, iii
51
manifestationof As poisoning
foot/hand drop
52
a 5HT-1A partial agonist that is used as anxiolytic with lesser chance of developing dependence
buspirone
53
the following anticoagulant drugs should be administered parenterally, except
dabigatran
54
the following condition aggravates the effect of digoxin except
hyperkalemia
55
MOA of aminophylline i. adenosine agonist ii. adenosine antagonist iii. pde inhibitor
ii, iii
56
weak acids are reasorbed in blood stream if
urinary pH is low
57
which direction would a partial agonist shift the dose-response curve when compared to a full agonist
down
58
a type of transport system where drug molecule is dissolved in acqeous medium and move along with the liquid through the pore
convective transport
59
a drug that reverse tthe effects of morphine and heroine by competitively blocking the opios receptors
naloxone
60
pegvisomat is used to treat
acromgaly
61
final metabolite of adrenaline and noradrenalin
vanillyl mandelic acid
62
rate limiting step of acetylcholine biosynthesis
active uptake of Ach
63
a non selective cox2 inhibitor with the highest risk of GI bleeding
oxicam derivative
64
amino acid precursor of cathecholamines
tyrosin
65
most nephrotoxic ammnoglycosides
neomycin
66
most hepatotoxic anesthetic gas
halothane
67
a woman who is suffering from hyperthyroidism is currently taking methimazole as treatment but upon knowing that the patient is pregnant, the physician changed the medication. this is because methimazole can cause what type of teratogenic condition?
aplasia cutis
68
hemorrhagic cystitis isa condition wherein the patient is experiencing symptoms including hematuria, and irritative voiding symptoms. this condition is also a side effect of what anti cancer drug
cyclophosphamide
69
antidote for gasoline poisoning
mineral oil
70
what disease does bauxite cause?
shaver's disease
71
antagonism that describes the ability of an agonist to inhibit the response to a second agonist via activation of different receptors that are physically separate
physiological antagonism
72
which of the following is classified as a thrombolytic agent?
reteplase
73
which of the following drug classes are typical antipsychotics
aota
74
which of th following diuretics should be used with precaution in patients under calcium duroles supplementation
acetazolamine
75
which of the following is least likely to cause sulfonamide like effect
ethacrynic acid
76
the substance that causes the hangover effects after drinking alcohol is
acetaldehyde
77
what agent may increase the chance of producing twins
clomiphene
78
aldosterone secretion is most likely to cause
hypernatremia
79
which of the following is used to manage digoxin induced arrgythmia
aota
80
the following drugs works by inhibiting enzymaatic reactions, except
acetazolamide
81
most antipsychotic drugs are capable of blocking
dopamine receptors
82
which of the following is most likely to have pulmonary side effects
propranolol
83
all are expected to manifest in patients under carbamate intoxication except
urinary retention
84
which of the following routes have 100% bioA?
IC
85
which of the following are likely to cause adverse effect in the liver
fibrates
86
a patinet under supplementation for a certain anemia is found to have stool discoloration. the patient is most like suffering
IDA
87
an active agent against m. leprae which causes skin discoloration ranging from red-brown to nearly black
aota
88
the DOC for schistosomiasis
praziquantel
89
an opioid derivative that is used to treat Parkinson's disease
apomorphine
90
the following are excitatory neurotransmitter except
glycine
91
the following can be effect of when RAAS is active, except
hyponatremia
92
the most common metabolism pathway of neonates
sulfation
93
metabolism occurs before it reaches the systemic circulation leading to decreased bioavailability
first pass metabolism
94
drug products that contain the same therapeutic moeity but as different salts, esters and complexes
pharmaceuticl alternative
95
drug products containing different active ingredients that are indicated for the same therapeutic or clinical objectives
therapeutic alternative
96
different dosage form and strengths within a product line by a single manufacturer
pharmaceutical equivalent
97
process of dispensing a therapeutic alternative in place of the prescribed drug product
therapeutic subsitution
98
process of dispensing a different brand or unbranded drug product in place of the prescribed drug product
generic substitution
99
the following transport mechanism does not require energy, except
pinocytosis
100
the following drugs can be a treatment for RA except
chloroquine