Week6-skeletal muscle

The DHPR are located in the plasma membrane.

Cross bridges are formed bw myosin and actin., The myofilaments do not change their length.

Spreads inward to all parts of the muscle via the T-tubules., Is essential for the contraction.

The DHPR is a voltage sensor., RyR is on the SR.

RyR is on the SR.

Action potential on scrcolemma., Ca++ binding to tropininC, Actin potential on T tubule.

SERCA has ATPase activity., Myosin has ATPase activity,, Tropinin C can bind Ca++.

It is larger than it needs to be to produce the muscle response., Is caused by the opneing of channels that permits the movement of Na+ and K+through the central pole., Produces a depolarization that results in a muscle action potential.

Is generated by a Na++ current., Produces a depolarization that results in a muscle AP., Is generated by K+ current.