Week5,6-sexual

blood testis barrier, expression of CYP19, secretion of Anti mullerian hormone, secretion of inhibin, they can phagocyte residual bodies, production of seminiferous fluid

the erigebr nerve innervating cavernous body is predominantly nitergic, insufficient androgen production may leads to erectile dysfunction, venous return from cavernous spaces decrease, inhibition of cGMP breakdown enhances erection, the reflex can be originated from mechanoreceptors of the glans and from upper brain centers as well

spermatogenesis is the formation of sperm cells, FSH indirectly stimulates spermatogenesis, spermatogenesis occurs in the seminiferius tubule, Sertoli cells provide nutrition of germ cells

the posess LH receptors., secretion of testosterone

neonatal, adult, fetal

Leydig cells contain Gs coupled LH receptors, the testosterone level is higher in the second trimester in the fetus right after delivery

The reflex can originate both from mechanoreceptors of the glans and from brain centers, It is accompanied by generalized para effects, The efferent axons are located in the erigent nerve

it is typically accompanied by the elevation of arterial blood pressure, it is produced by NE NT and is supported by somatic motor nerve, The reflex can be originated from the mechanoreceptors of the glans and from upper brain centers as well., It is accompanied by generalized sympathetic tone increase

phenotypic sex is determined by the hormones produced by the gonads, chromosomal sex is determined by presence or absence of Y chromosome, peripheral testosterone production correlates with adult reproductive orientation, gonadal sex is controlled by presence or absence of testis determining

early in fetal life, germ cells migrate from yolk sacs to the genital ridge, SRY decreases Wnt4 expression, Wnt4 contributes to the formation of the Müllerian duct

adrenarche does not occur in gifs with Addison disease, at the begging of puberty GnRH secretion becomes pulsatile, Wnt4 promotes female sex development, menarche is the first menstrual cycle, the level of AMH is higher in males even after birth, SRY decreases Wnt4/B cathenin signaling, Wnt4 contributes to the formation of the Müllerian duct, early in fetal life, germ cells and genital ridge are bipotential

SRY decreases Wnt4, adrenarche does not occur in girls with Addison, Wnt4 promotes female sex development, at the beginning of puberty GnRH secretion becomes pulsatile

LH, FSH, Estradiol

high level of 17b estradiol has a positive fb in pituitary gonadotropes, 17OHprogesteron induces the rupture of mature of follicle

the dominant follicle expresss the highest level of FSH receptor, synthesis of progesterone is greatly increased after ovulation, increasing level of FSH induces the growth of a group of follicles, high concentration of estrogen causes the LH surge, LH level gradually increases, increasing level of E2 inhibits gonadtrop FSH secretion

during pegnancy P4 inhibits the immunological rejection of the fetus, P4 is secretes by the corpus luteum, induces breast proliferation, helps to maintain gestation by reducing the excitability of the myometrium, facilitates implantation of the embryo, reduces oxytocin sensitivity of the myometrium

its levels are elevated in the seconda phase of menstrual cycle, it facilitates the development of secretory endometrium, it maintains gestation, it has a negative fb effect on the secretion of LH

without hCG it dies at the end of the literal phase, produces progesterone, produces estrogens, LH receptor is expressed on the plasma membrane of its cells

insufficient androgen production may lead to erectile dysfunction, venous return from cavernous spaces decreases, the blood flow into sinusoids cavernous spaces via helicjne arterioles increases

high concentration of estrogen causes the LH surge, synthesis of progesterone is greatly increased after the ovulation

the reflex can be originated from upper brain centers, the reflex can be originated from the mechanoreceptors of the glans, the efferent axons are located in the pudendal nerves, it is accompanied by generalized sympathetic tone increases

the body temperature is higher than follicular phase, hCG secretion of the implanted embryo rescues the corpus luteum, high level of progesterone inhibits FSH secretion