問題一覧
1
What are the fungal cell components (3examples)?
Cytoplasmic membrane with ergosterin, cell wall made of chitin, glucan, or cellulose.
2
Classification the fungi by morphology?
Unicellular or yeast, multicellular or mould and dimorphic
3
Characterisation of the dimorphic fungus
They grow as moulds at room temperature and grow as yeast at body temperature.
4
5. What is the cultivation temperature of the fungi?
25°C and 37°C to detect the dimorphism
5
What kind of culture media can be used to cultivate fungi?
Sabouraud culture media.
6
List at least two asexual spore type.
Blastopore, conidia, arthrospore, spherule.
7
What are the contents (2 examples) of Sabouraud culture media?
Antifungal agents against environmental moulds, carbohydrates, antibiotics.
8
What kind of diseases can be caused by fungi?
Allergic reactions, intoxications, mycosis (tissue damage of fungi).
9
What kind of staining can be used in mycology? (2 examples)
Gram-, methylene blue-, India ink-, PAS-, Gömöri-Grocott staining.
10
Classification of the mycosis?
Superficial, cutaneous, subcutaneous, systemic, and opportunistic mycosis.
11
Mode of action of the antifungal drugs?
Inhibition of ergosterin synthesis, pore formation on membrane, inhibition of nucleic acid synthesis, inhibiion of cell division
12
Which antifungals produce pores on fungal cell membrane?
Amphotericin B, Nystatin
13
List three pathogens causing systemic mycosis!
Coccidioides immitis, Histoplasma capsulatum, Blastomyces dermatitidis, Paracoccidoides brasiliensis
14
List two causative agent of dermatomycosis!
Trichopyton sp., Microsporum sp., Epidermophyton sp
15
What are the sources of the infections caused by dermatophytes?
Anthropophil – human, geophil– soil, zoophil – animal
16
19. What kind of diseases can be caused by dermatophytes? (3 examples)?
Tinea pedis, T. manus, T. capitis, T. corporis, T. faciei, T barbae.
17
What is the most common causative agent of superficial mycosis?
Malassezia furfur
18
Which fungus can cause subcutaneous mycosis?
Sporothrix shenkii
19
List three causative agent of opportunistic mycosis.
Candida sp, Cryptococcus neoformans, Pneumocystis jirovecii, Aspergillus sp., Penicillium sp., Mucor sp., Rhizopus sp.
20
What type of infections are caused by Coccidoides immitis?
Pneumonia, meningitis
21
What type of infections are caused by Histoplasma capsulatum? (2 examples)
Granuloma of the lung, lyph nodes, skin, and meningitis
22
What type of infections are caused by Blastomyces dermatitidis? (2 examples)
Pneumonia, skin nodules, ulcers, meningitis, brain abscess
23
What type of infections are caused by Paracoccidiodes brasiliensis?
Lung infection resembling TB, ulcers of skin and mucosa
24
What type of infections are caused by Cryptococcus neoformans?
Lung infection and meningitis
25
What type of infection is caused by Pneumocystis jirovecii?
Interstitial pneumonia of immunosupressed patients
26
List 5 Candida species!
Candida albicans, Candida tropicalis, Candida krusei, Candida glabrata, Candida parapsilosis
27
List two 2 Trichophyton species!
Trichphyton rubrum, Trichphyton schonleinii, Trichphyton tonsurans, Trichphyton verrucosum