問題一覧
1
What are the contents (2 examples) of Sabouraud culture media?
Antifungal agents against environmental moulds, carbohydrates, antibiotics.
2
Which antifungals produce pores on fungal cell membrane?
Amphotericin B, Nystatin
3
What are the fungal cell components (3examples)?
Cytoplasmic membrane with ergosterin, cell wall made of chitin, glucan, or cellulose.
4
List at least two asexual spore type.
Blastopore, conidia, arthrospore, spherule.
5
What is the most common causative agent of superficial mycosis?
Malassezia furfur
6
5. What is the cultivation temperature of the fungi?
25°C and 37°C to detect the dimorphism
7
List 5 Candida species!
Candida albicans, Candida tropicalis, Candida krusei, Candida glabrata, Candida parapsilosis
8
What type of infection is caused by Pneumocystis jirovecii?
Interstitial pneumonia of immunosupressed patients
9
List two 2 Trichophyton species!
Trichphyton rubrum, Trichphyton schonleinii, Trichphyton tonsurans, Trichphyton verrucosum
10
What kind of culture media can be used to cultivate fungi?
Sabouraud culture media.
11
List three pathogens causing systemic mycosis!
Coccidioides immitis, Histoplasma capsulatum, Blastomyces dermatitidis, Paracoccidoides brasiliensis
12
What are the sources of the infections caused by dermatophytes?
Anthropophil – human, geophil– soil, zoophil – animal
13
Classification the fungi by morphology?
Unicellular or yeast, multicellular or mould and dimorphic
14
Which fungus can cause subcutaneous mycosis?
Sporothrix shenkii
15
Mode of action of the antifungal drugs?
Inhibition of ergosterin synthesis, pore formation on membrane, inhibition of nucleic acid synthesis, inhibiion of cell division
16
What kind of diseases can be caused by fungi?
Allergic reactions, intoxications, mycosis (tissue damage of fungi).
17
What kind of staining can be used in mycology? (2 examples)
Gram-, methylene blue-, India ink-, PAS-, Gömöri-Grocott staining.
18
List two causative agent of dermatomycosis!
Trichopyton sp., Microsporum sp., Epidermophyton sp
19
19. What kind of diseases can be caused by dermatophytes? (3 examples)?
Tinea pedis, T. manus, T. capitis, T. corporis, T. faciei, T barbae.
20
Classification of the mycosis?
Superficial, cutaneous, subcutaneous, systemic, and opportunistic mycosis.
21
List three causative agent of opportunistic mycosis.
Candida sp, Cryptococcus neoformans, Pneumocystis jirovecii, Aspergillus sp., Penicillium sp., Mucor sp., Rhizopus sp.
22
What type of infections are caused by Blastomyces dermatitidis? (2 examples)
Pneumonia, skin nodules, ulcers, meningitis, brain abscess
23
Characterisation of the dimorphic fungus
They grow as moulds at room temperature and grow as yeast at body temperature.
24
What type of infections are caused by Paracoccidiodes brasiliensis?
Lung infection resembling TB, ulcers of skin and mucosa
25
What type of infections are caused by Histoplasma capsulatum? (2 examples)
Granuloma of the lung, lyph nodes, skin, and meningitis
26
What type of infections are caused by Coccidoides immitis?
Pneumonia, meningitis
27
What type of infections are caused by Cryptococcus neoformans?
Lung infection and meningitis