Week11

1200 1000

1200 800

3100 1900

2400 1800

4800 3200

6000 4200

500

whole body plethysmography, helium dilution technique

the amount of air that normally moves into (or out of) the lung with each respiration., around 500 mL in healthy adults.

It can be measured by spirometry., It is the volume difference bw TLC and RV.

FEV1, Tiffeneau index

VC, RV, ERV, TV

PEF of 8 L/sec., Intrapleural pressure with relaed respiratory muscles of -4cm H2O.

highly depends on the bronchial smooth muscle tone., can be decreased by the inhalation of B2 receptor agonists., can be pharmacologically modulated.

Decreased alveolar pO2 stimulates spontaneous breathing., Increased alveolar pCO2 stimulates spontaneous breathing., Voluntary hyperventilation decreases alveolar pCO2.

to reduce the possibility of plumonar edema., to equalize pressure in large and small alveoli, to decrease surface tension, protects small alveoli from collapse, reduces the work of respiration, prevents from pulmonary edema

24 9

Diastolic BP in the plumonary artery is 9 mmHg., It contains about 10% of the blood volume., Systolic BP in the plumonary artery is 24 mmHg., Local hypoxia induces vasoconstriction.

When the respiratory muscles are relaxed and the airway is open, At the end of a normal expiration., When lung recoil is balanced by chest wall expansion.

The diaphragm contracts., The activity of the phrenic nerve increases., The intrapleural pressure decreases to 7 cm H2O below barometric pressure.

It is needed for the calculation of Tiffeneau index., It can be measured spiroscopy., It is the volume difference bw the TC and RV.

Type2 alveolar cells produce surfactant.