問題一覧
1
Which cytoskeletal component play a crucial role in cytokinesis?
Actin and myosin filaments
2
TGT to TGG cys to trp
missense
3
A synaptonemal complex is:
Aladderlikestructurethatformsinpairingofhomologouschromosomesmeiosis
4
How many tetrads are found in meiotic prophase in an organism with a diploid number of 12?
6
5
The human genome is:
All of our DNA
6
A 47, XXY karyotype may be caused by the non-disjunction of __________
Meiosis II in either parent
7
give the number of chromosomes, a soeematid
23
8
In meiosis I anaphase:
Homologous chromosomes move toward opposite poles
9
The number of DNA molecules in the nucleus of a diploid human cell in G1 phase
46
10
Which proteins are encoded by tumor suppressor genes?
cycline dependent kinase inhibitors
11
Which type of chromosome abnormality is characteristic for the centric fusion?
structural aberration
12
Klinefelter’s syndrome (XXY) is an example of chromosomal aneuploidy that can readily be diagnosed by:
Karyotyping
13
give the number of chromosomes, a primaryoocyte
46
14
GAG to GTG disease
sickle cell anemia
15
Which stage of meiosis is the physical basis for Mendels law of independent assortment?
Anaphase I
16
What is the requirement for passing the restriction point?
phosphorylation of pRb
17
TGT to TGA
nonsense
18
Differences between meiosis and mitosis include all of the following EXCEPT
Each mitotic cell division and each second meiotic division is preceded bya complete round of DNA synthesis
19
What can be the consequence in the offspring, if one of the parents is a carrier for Robertsonian translocation between chromosome 14 and 21?
The offspring will either have Down syndrome or normal phenotype.
20
give the number of chromosomes, secondary soermatocyte
23
21
Polyploidy refers to:
An individual with complete extra sets of chromosomes
22
Which is correct?
MPF triggers the mitosis and meiosis as well
23
Choose the correct statement for the M-phase
At the beginning of prophase the nuclear envelope disintegrates
24
Alleles that are both expressed in a heterozygote are
Codominant
25
During anaphase II (meiosis II)
Sisterchromatidsseparateandmigratetowardsoppositepoles
26
A disease caused by an autosomal non-disjunction is
Down syndrome
27
Burkitt lymphoma
reciprocal translocation
28
What characterize the inactive MPF?
It is the substrate of kinases and a phosphatases
29
Homologous chromosomes are NOT necessarily identical in their _______
alleles
30
During the mitosis the spindle fibers connect to the:
kinetochores
31
give the number of chromosomes, a cell formed after soermiogenesis
23
32
Which is not true for the structural chromosome aberrations?
One or more extra copy of chromosome is in the cell
33
A man with type A blood marries a woman with type B blood. If both parent are homozygous, their offspring will have type _____ blood, which is an example of ___
AB; codominance
34
What is true for the chromosomes?
The DNA sequence of the two sister chromatids are identical
35
give the number of chromosomes, the polar body formed along with a secondary oocyte
23
36
TGT to TGC (cys to cys)
silent
37
What is not true for the cell cycle regulation?
Theinhibitoryphosphateisremovedbyactivatingkinase
38
A human genetic defect that is caused by non-disjunction of sex chromosome is
Turner syndrome
39
What is true about kinetochore?
It is a protein complex added to the centromere region of chromosomes
40
give the number of chromosomes, a cell resulting from mitosis division of spermatogonium
46
41
What is true about sister chromatid exchange?
It has no genetic consequence in most of the cases
42
Which of these statements about the difference between mitosis and meiosis is true?
Sister chromatids separate during mitosis and meiosis II, but not during meiosis I
43
Choose the correct statement for cell cycle
M-phase is completed after the inactivation of MPF
44
In a population expressing five different alleles for a particular gene, how many alleles may be present in each diploid organism in the population?
2
45
In meiosis, what is meant by a tetras of homologous chromosomes?
Four chromatids in the unit
46
In which phase or stage do sister chromatids separate during meiosis?
In anaphase II
47
TRUE for cell cycles
The DNA content of the cell is duplicated before mitosis.
48
The number of chromosomes in a zygote is
The same as in a skincell
49
Down syndrome results from:
Thepresenceofanextrachromosomeinposition21