問題一覧
1
Pharmacological action of carbachol
Act predominabntly on GIT, UB , For Glaucoma, nicotinic actions>Muscarinic actions :
2
Muscle weakness & fatigue people with myasthenia gravis
Ambenonium
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What are under direct acting
Choline ester, Alkaloids
4
Scopolamine
Hyoscine
5
Used for ophthalmic solution
Demecarium
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Lowers / Decrease acetylcholine level
Vesamicol.
7
Agonist dont stimulate and bond
Indirect acting
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What is the downside of ganglionic blocker why it is less prescribed
Reverse dumbbells , Adverse effects.
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Directly bind to antagonist
Direct
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Stimulate receptors of acetylcholine.
Alkaloids.
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Not hydrolyzed by cholinesterases
Betanechol, Methacholine
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What is the release inhibitor in SNS
Brethylium
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What are under alkaloids
Pilocarpine , Muscarine, Nicotine , Arecholine, Varenecline
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What is the brand name of physostigmine
Eserine.
15
Use for diagnostic for provocation testing/ Diagnostic asthma
Methacholine.
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What is the generic name of Ambenonium
Mytelase.
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Smooth muscle like pupil and bronchioles
M3
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In Alkaloids what is the only drug for glaucoma
Pilocarpine
19
Capable to increase the acetylcholine level in body
Indirect
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What are under reversible
Quaternary alcohol , Carbamates
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from Areca nut
Arecoline.
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What are under choline ester
Acetylcholine , Metacholine , Carbachol , Betanechol
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M1 blocker and for P.U.D
Pirenzipine, Telenzipine
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Atropine
Hysosyamine
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From leaves of jaborandi
Pilocarpine.
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It decreases. ocular pressure = Increase the drainage aqueous
Miosis
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more resistant to enzymatic hydrolysis than ACh.
Methacholine.
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What is the inhibitor of vesicles in SNS
Reserpine
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For mushrooms poisoning
Muscarinic
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Cannot cross BBB
Neostigmine
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Attach to the ACHE enzyme and are only slowly hydrolyzed.
Reversible inhibitor
32
A beta 2 agonist
Salbutamol.
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What is the most toxic nerve gas?
Tabuun.
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What is yhe generic name of pyridostigmine
Mestinon
35
What are drugs used for the treatment of myasthenia gravis
Neostigmine , Ambenonium, Pyridostigmine.
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What is yhe generic name of demecarium
Humorsol.
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Reacts to form a stable, phosphorylated enzyme, which is essentially not hydrolyzed.
Irreversible inhibitor
38
What is the rate limiting step in PNS
Hemicholinium
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What are under quaternary alcohol
Edrophonium
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What are under cholinergic agonist
Direct acting , Indirect acting
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Ganglionic blocker can cause?
Antihypertensive , Activates SNS and PNS
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Long acting for about 2-3 hours.
Carbamates
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Pharmacological action of betanechol
Act predominabntly on GIT, UB. , No nicotinic actions
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What are the drugs used for glaucoma
Demecarium , Pilocarpine , Ecothiophate, Carbachol
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dont form a covalent bond and a short acting
Quaternary alcohol
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What is the generic name of methacholine
Mecholyl.
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What are under organoleptic used as insecticide
Parathion , Malathion
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diagnosis of Myasthenia gravis
Endophonium
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Im what disease does decrease level of dopamine and has a High level of acetylcholine
Parkingson
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What is the generic name of betanchol
Urecholine
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What are medicine for bronchial asthma and PUD
Ipratropnium, Oxytropnium., Triotropium.
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Has a muscarinic action similar to ACH
Pilocarpine, Muscarine
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What are under carbamates
Neostigmine , TDGR, Demecarium, Ambenonium, Physostigmine
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What are under organophosphate
Parathion , Nerve gases, Ecothiophate, Malathion
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An autoimmune disease
Myasthenia gravis
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Why is in Choline ester betachol and methacholine is resistance in acetylcholinesterase and has a lower nicotinic activity
Presence of methyl substituents in Beta carbon
57
management of wrinkles
Butox.
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What is the pharmacology action of neostigmine
Post operative ileus, Urinary retention , Reverse Vms Block, Myasthenia gravis
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What is the release inhibitor in PNS
Botox.
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What is the uses of betanechol
Gastric retention , Postoperative abdominal distention, Nonobstructive urinary retention , Prevention of paralytic ileus
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very potent choline ester having both muscarinic and nicotinic effects
Carbachol.
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Treat glaucoma by decreasing the pressure inside the eye
Demecarium.
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Raidly hydrolyzed and. A quaternary ammonium compounds cannot penetrate
Acetylcholine.
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Chronic nicotinic toxicity
Nicotine.
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What is the plant sources or nicotine
Nicotiana tabacum
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Uptake of choline or vesicles
Hemicholinium
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endophonium also know as?
Tensilon.
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Short acting and test used for myasthenia gravis.
Endophonium.
69
What are under indirect acting
Reversible , Irreversible
70
Tertiary amine and well absorbed orally
Alkaloids
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can cross BBB
Physostigmine
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Methacholine mecholyl pharmaceutical action is?
Muscarinic actions =Ach. , Clinical Use: not used clinically, No nicotinic actions
73
Smoking sensation
Nicorrete gum or patch
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Bradycardia/ lower heart rate
M2
75
What is under irreversible
Organophosphate
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Not intend to use for industrial purposes and only for Biological weapon
Irreversible.
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What is the generic name of neostigmine
Prostigmine.
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Respiratory paralyzed
Nicotine.
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What is the inhibitor of vesicles in PNS
Vesamicol.
80
What is the rate limiting step in SNS
Metyrosin
81
It only increase the level of acetylcholine by inhibiting acetylcholinesterase
Indirect acting.
82
Drugs that can treat Myasthenia gravis
Ambenonium., Neostignine
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Found in stomach and acud secretion
M1
84
Used for inflammation
Cyclopenlate
85
What are medicine used for parkingson
Bensotropine, Biperiden, Trihexyphenidyl.
86
What are under of choline este that is resistance in nicotinic and muscarinic
Betanchol, Methacholine
87
What is the pharmacologic effect of physostigmine
Opthalmic , poisoning anticholinergic agent