PUD.

45問 • 1年前

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Secreted form the parietal cells in the body of the stomach Its release is Regulated by endocrine, Paracrine and neurocrine cells

Hydrochloric acid.

It helps the body to break down, digest, and absorb nutrients such as protein. It also eliminates bacteria and viruses in the stomach, protecting the body from infection.

Hydrochloric acid.

The acid level of the digestive system rises above normal. The acids erodes the lining of the digestive tract giving a burning like sensation in the stomach

Hyperacidity.

general inflammation of the gastric mucosa

Gastritis.

circumscribed loss of mucus membrane of the stomach

Peptic ulcer.

a circumscribed loss of the mucous membrane of the GIT system exposed to gastric juices containing acid and pepsin.

Peptic ulcer disease.

Imbalance between aggressive factor and defensive factors.

Peptic ulcer disease.

What is the transmission of H.pylori?

Fecal oral.

What H.pylori secret that it survive in alkaline ph.

Urease.

weakens mucous coating of the stomach and duodenum, thus allowing acid to get through to the sensitive lining beneath

Peptic ulcers disease.

Inhibition of COX-1 in the gastrointestinal tract leads to a reduction of prostaglandin secretion and its cytoprotective effects in gastric mucosa

Nsaid.

prostaglandin analogue that can increase mucus production in the stomach (obsolete= abortifacient effect)

Misoprostol.

A painful sore located in the lining of the lower part of the esophagus, at the junction of the esophagus and stomach

Esophageal ulcer.

Esophagus is the tube connecting throat and the stomach. (T/F)

True.

Esophagitis that is meal-related is primarily due to reflux of stomach contents

Gerd.

Open sores that develop on the lining of the stomach.

Gastric ulcer.

Primary caused by drugs (NSAID induced) or H. pylori infection

Gastric ulcer.

It can develop into malignancy or gastric cancer

Gastric ulcer.

Gnawing or burning pain in the upper abdomen (relieved by eating food but it may persist even after eating

Gastric ulcer.

peptic ulcer that develops in the first part of the small intestine

Duodenal ulcer.

Gnawing or burning pain in the upper abdomen (relieved by eating food but reappears 1-3hrs after meal )

Doudenal ulcer.

due to pyloric channel or duodenal ulcers causes incapacitating crampy abdominal pain may lead to total obstruction with intractable vomiting

Scarring.

5% patients and 66% of ulcer deaths and most common cause by ulcer.

Perforation.

25-33% of patience and 25% ulcer death and it is the first indication of an ulcer.

Bleeding.

Reduce pain and may promote healing (high doses 40meq of antacid 7x daily) (T/F)

True.

WEAK BASES that are taken orally which reacts with gastric acids

Antacids.

Slow onset, long duration

Aluminum hydroxide.

Fast onset, LONG duration

Calcium carbonate.

Fast onset, short duration

Magnesium hydroxide and Sodium bicarbonate.

Ideal dosing interval: 1 and 3 hr after meals and at bedtime

Antacids.

Heart failure = excess sodium intake (t/f)

True.

Renal failure = should not use magnesium (T/F)

True.

rapid onset of action but short duration of action

Sodium bicarbonate.

absorbed systemically and should not be used for long-term treatment. Contraindicated to hypertension due to its high sodium content

Sodium bicarbonate.

fast onset of action with long duration of action

Calcium carbonate.

rapid onset of action but short duration of action. All magnesium salts are used as antacid

Magnesium hydroxide.

slow onset of action but long duration of action

Aluminium hydroxide.

decrease gastric acid secretion through competitive inhibition of H2 receptors

Histamine 2.

- GERD (reflux disease) - Short term tx for Duodenal and gastric ulcer

Histamine 2.

These drugs suppress the secretion of hydrochloric acid into the lumen of the stomach

Proton pump inhibitors.

it inhibits the absorption of ketoconazole ◦ contraindicated in pregnancy

Omeprazole.

it can increase theophylline clearance it is contraindicated in asthma

Lansoprazole.

These are agents that coat any injured area in the stomach to prevent further injury from acid

Cytotprotectant.

is a 14 amino acid peptide that is released in the gastrointestinal tract and pancreas from paracrine cells, D-cells, and enteric nerves as well as from the hypothalamus

Somastatin.

is a synthetic octapeptide with actions similar to somatostatin.

Octreotide.

Cell structure.

Quinn Karylle Fuentes · 28問 · 2年前

Cell structure.