問題一覧
1
Refers to a two-phase system consisting of a finely divided solid dispersed (suspended) in a liquid (the dispersing medium).
Suspension.
2
What do you call a finely divided solid dispersed
Suspended.
3
Preparations containing finely divided drug particles (the suspensoid) distributed somewhat uniformly throughout a vehicle in which the drug exhibits a minimum degree of solubility
Suspension.
4
A finely divided drug particles.
Suspensoid.
5
Disperse system in which solid, vehicle-insoluble particles.
Internal phase.
6
are uniformly suspended by mechanical agitation and formulation design throughout the liquid vehicle.
External phase.
7
The solid particles is greater than 1um
Suspension.
8
Most good pharmaceutical suspensions?
1-50.
9
What are the classification of suspension.
Oral, Topical and Parenteral Suspension.
10
Suspension shoud settle slowly and should be readily redispersed upon gentle shaking. (True/False)
True.
11
Suspension particles size should remain fairly constant throughout long periods of undisturbed standing.(True/False)
True.
12
Pour readily and evenly from its container. (True/False)
True.
13
Sedimentation rate 2.5 um powder in water.
1.02×10-⁴
14
0.25 um powder un water
1.02×10-⁶
15
2.5 powder in glycerin
4.25×10-⁸
16
0.25 powder in glycerin
4.25×10-¹⁰
17
Reduction is accomplished by the use of dry milling, micropulverization (10-50 um)
Dispersed phase.
18
Finer: < 10 um by fluid energy grinding
Jet milling.
19
For parenteral or ophthalmic suspension
Spray drying.
20
extremely small dimensions
Spray particles.
21
Small particles reduces sedimentation rate but may pose a problem on forming hard sediment. (True/False)
True.
22
an aggregation of particles
Flocs.
23
Suspension in which particles have undergone flocculation.
Flocculated.
24
Suspension in where no flocculation taken place.
Deflocculated.
25
Has floccules.
Flocculated.
26
Has no floccules.
Deflocculated.
27
The rate sedimentation is high.
Flocculated.
28
The rate sedimentation is low.
Deflocculated.
29
The volume of sediment is high.
Flocculated.
30
the Volume of sediment is low.
Deflocculated.
31
Form porous sediments.
Flocculated.
32
Form non-porous sediments.
Deflocculated.
33
The re-dispersion of a sediment can easily be dine by agitation.
Flocculated.
34
The re-dispersion of a sediment can difficult be done by agitation
Deflocculated.
35
enhance particle “dispersibility”.
Flocculating agent.
36
reduce sedimentation rate in the flocculated suspension
Viscosity enhancer.
37
increases penetration by the dispersion medium
Wetting agent.
38
any additive used in substance and compounds to keep them stable, retard deterioration
Stabilizer.
39
prevents the growth of microorganisms
Preservatives.
40
For oral suspension
Dry powders for suspension.
41
Barium sulfate for suspension
Rectal suspension.
42
• Antacid oral suspensions, •Antibacterials, •Antiprotozoal and •Anti-inflammatory
Shake well instruction.
43
Wet the powders using wetting agents like alcohol, glycerin, propylene glycol and other hygroscopic agents
Prep for suspension.
44
Use colloid mills or mortar and pestle to effect thorough mixing
Prep for suspension.
45
Add the dispersion medium to which other soluble components are dissolved
Prep for suspension.