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1
This is used to view viruses as they are too small for conventional microscope
ELECTRON MICROSCOPE
2
Herpes causing viruses
INFECTIOUS MONONUCLEOSIS, EPSTEIN BARR VIRUS, CYTOMEGALOVIRUS
3
This refers to the submicroscopic particle
VIRUS
4
What is the basic structure of virus
NUCLEIC ACID
5
In virology, viruses are differentiated into 2 structures which are
DNA, RNA
6
Refers to pathogens which needs living host to survive
INTRACELLULAR
7
What rule do bacteria follows to reproduce
BINARY FISSION
8
Bacteria needs an agar to be called cultivated while viruses needs
LIVING CELL
9
Considered to be the best cell for virus cultivation
RHESUS KIDNEY CELL
10
The most famous cultivating medium for viruses which derives from cervical cancer cell
HELA CELL
11
Cancer cells are considered to be ? Which making them as ideal cultivating media for viruses
IMMORTAL
12
What is the type of immunity that serves as the first line of protection against viruses
INNATE IMMUNITY
13
What are the first line of protection in which inhibits viral replication and enhances activity of nk cells
INTERFERON A, INTERFERON B
14
These are considered to be our defense when it comes to viruses and it serves as a bridging between innate and adaptive immunity
NATURAL KILLER CELL
15
Natural killer cells have this enzymes which creates pores on viruses causing the extracellular fluid to go inside the cell promoting lysis
PERFORIN, GRANZYME
16
What is release from the virus after lysis
ANTIGEN FRAGMENT
17
These are the cells that presents the antigen fragments to the adaptive immunity
ANTIGEN PRESENTING CELL, MAJOR HISTOCOMPATIBILITY COMPLEX
18
This type of immunity involves the b cell and plasma cell which produces virus specific antibodies
HUMORAL IMMUNITY
19
This is form when b cells are exposed to antigen fragments which further mature producing virus specific antibodies.
PLASMA CELL
20
This prevents the spread of viral replication through neutralization
ANTIBODY
21
Antibody which promotes phagocytosis through opsonization
IGG
22
Antibody which promotes agglutinates viral particles
IGM
23
Igm and igg have one important function which is to activate this substances leading to lysis
COMPLEMENT
24
What are the specific cells involves in the cellular defense mechanism program to expand in number and attack the virus infected cell
CD4 HELPER T CELL, CYTOKINE, CD8 CYTOTOXIC T CELL
25
This is similar to natural killer cells which produces proteins and proteases
CD8 CYTOTOXIC T CELL
26
Cytotoxic T cells increases to how many times to its original number
50000
27
This is the capability of viruses which produces new viral antigens causing to be not recognized immediately by initial immune response
FREQUENT GENETIC MUTATION
28
This virus can evade actions of the component of the immune response which blocks interference making degradation viruses impossible
HEPATITIS C VIRUS
29
This viruses can evade the host defense by suppressing the immune system
HIV, CYTOMEGALO VIRUS
30
HIV targets what cell
CD4 T CELL
31
Cytomegalovirus suppress this part of immune system disabling to present antigen
MAJOR HISTOCOMPATIBILITY COMPLEX
32
This antibodies indicates current or recent viral infection
VIRUS SPECIFIC IGM ANTIBODY
33
This antibody indicates current or past viral infection in most cases of immunity
IGG
34
This immunoglobulins mainly maternal antibodies
IGG
35
Specific igm antibody in newborns indicates
CONGENITAL INFECTION
36
This is the general term of inflammation of the liver
HEPATITIS
37
What are the possible cause of hepatitis
VIRAL INFECTION, CHEMICAL, IONIZING RADIATION, AUTOIMMUNE PROCESS
38
Acute stage of hepatitis have this symptom
FLU LIKE
39
Progressive stage of hepatitis have this symptoms
HEPATOMEGALY, JAUNDICE, DARK URINE, LIGHT FECES
40
This substances have elevations in initial laboratory test indicating a possible hepatitis disease
TOTAL BILIRUBIN, LIVER ENZYME
41
This is the waste product of heme which is toxic and non-water soluble
INDIRECT BILIRUBIN
42
This is the important carrier protein which delivers unconjugated bilirubin to the liver
ALBUMIN
43
A further converted conjugated bilirubin which is responsible for the color of urine and also excreted into the urinary system
UROBILIN, UROCHROME
44
This is form from further conversion of conjugated bilirubin which is excreted via stool
STERCOBILIN
45
This refers to the accumulation of indirect bilirubin in the brain cause by hepatitis
KERNICTERUS
46
Also known as? Which is non envelope single stranded ribonucleic acid virus responsible for 10 millions of infection worldwide
HEPATITIS A, INFECTIOUS HEPATITIS
47
Hepatitis a belongs to the hepatovirus genus of
PICORNAVIRIDAE SSRNA
48
What are the possible transmission of hepatitis a
FECAL, ORAL, CLOSE CONTACT, CONTAMINATED FOOD
49
What is the course of infection of hepatitis a? Resolves in how many months
ACUTE, 2
50
What is the serological marker in the diagnosis of hepatitis a
IGM ANTIBODY
51
Demonstration of igm antibody to hepatitis a virus is detected via
SOLID PHASE ANTIBODY CAPTURE ENZYME IMMUNOASSAY
52
Test for total hepatitis a virus which detects igg
COMPETITIVE INHIBITION ENZYME IMMUNOASSAY
53
This persist for life and it is considered as the forever marker of infection
IGG
54
What are the test for the virus itself
POLYMERASE CHAIN REACTION, NUCLEIC ACID TEST
55
This is the major cause of mortality and morbidity worldwide of hepatitis
HEPATITIS B
56
The only dna virus in hepatitis viral infection
HEPATITIS B
57
What is the mode of transmission of hepatitis b
PARENTERAL, SEXUAL, PERINATAL, ORAL
58
What is the serological marker the diagnosis of hepatitis b
ANTIBODY, ANTIGEN
59
Hepatitis b belongs to the genus of what family
HEPADNAVIRIDAE DSDNA
60
Disappear shortly after hbsag which may be elevated during acute phase and present during period of active replication
HBeAG
61
This must be negative when applying for interns in medical technology as this indicates that virus has high degree of infectivity
HBeAG
62
Marker for hepatitis b which is not detected in the serum
HBcAG
63
First to appear antigen which indicates current or recent infection of Hepatitis B
IGM ANTI HBc
64
This refers to the period of time in which the patient suffers a possible infection without any symptoms
WINDOW
65
This is also known as the zero conversion in which the antibodies are still starting to produce
CONVALESCENCE
66
Which part of the blood has the highest concentration of virus
PLASMA
67
This marker can be tested in which may suggest that the vaccine for hepatitis b is needed a booster or not
ANTI HBs
68
Also known as? Which is asymptomatic but problematic because it may lead to chronic infection
HEPATITIS C, MAJOR PUBLIC HEALTH PROBLEM, POST TRANSFUSION HEPATITIS, NON A NON B HEPATITIS
69
What is the average incubation period of hepatitis c
7 WEEK, 15-150 DAY
70
Transmission of hepatitis c
CONTAMINATED BLOOD, BLOOD TRANSFUSION, ORGAN TRANSPLANTATION, HEMODIALYSIS
71
Type of hepatitis which sexual transmission is less common and has no acute stage
HEPATITIS C
72
What is the screening test of hepatitis c
DETECTION OF HCV IGG ANTIBODY USING THIRD GENERATION
73
What is the confirmatory test for hepatitis c
RECOMBINANT IMMUNOBLOT ASSAY, MOLECULAR METHOD
74
This is also refers to as the most common blood transfusion hepatitis
HEPATITIS C
75
Is also known as? Which parenterally only occur in the presence of hepa b
HEPATITIS D, DELTA HEPATITIS
76
Hepatitis d is a defective virus that needs what hepatitis to complete its replication
HEPATITIS B
77
Hepatitis d infection is indicated by the presence of? In patient serum
ANTI HDV
78
Test used to diagnose hepatitis d
IMMUNOASSAY EMPLOYING HEPATITIS D ANTIGEN
79
Test used to diagnose acute hepatitis d infection
IGM ANTI HDV
80
This is the most severe form of viral hepatitis
HEPATITIS D
81
Type of hepatitis which transmission is also through ingestion of heavily contaminated drinking water in developing countries in which there is no treatment
HEPATITIS E
82
What is the incubation period of hepatitis e
3-8 WEEK, 15-60 DAY
83
Hepatitis e causes self limiting hepatitis that last for how many weeks in most people who became infected
1-4 WEEK
84
The diagnosis of hepatitis e relies on
SEROLOGIC TEST
85
Acute infection of hepatitis e demonstrate the presence of? Detectable during clinical onset
IGM ANTI HEV
86
IGM ANTI HEV is identified by
HIGHLY SENSITIVE ENZYME IMMUNOASSAY
87
What is the other name of hepatitis b
SERUM HEPATITIS
88
What family do hepatitis c belongs
FLAVIVIRIDAE SSRNA
89
What family do hepatitis e belongs
HEPEVIRIDAE SSRNA
90
Incubation period of hepatitis d
30-60 DAY
91
Incubation period of hepatitis b
45-160 DAY
92
Incubation period of hepatitis d
30-60 DAY
93
Which hepatitis is transmitted through hemodialysis
HEPATITIS C
94
What hepatitis it has a clinical significance of acute and self limiting
HEPATITIS A
95
What hepatitis which is chronic and about 10 to 90% of infected individuals develops cirrhosis and risk for ca
HEPATITIS B
96
What hepatitis has an 80 to 85% will develop a chronic disease while 15 to 20% will have an spontaneous resolution
HEPATITIS C
97
What hepatitis has the super infection or co infection with hepatitis b
HEPATITIS D
98
What hepatitis is acute self limiting culminant liver and it is a failure in pregnant woman
HEPATITIS E
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