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MAJOR HISTOCOMPATIBILITY

  • Jef Marc Valencia

    • 問題数 26 • 9/9/2024

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  • 1

    discovered how to fuse lymphocytes to produce a single cell line. This single cell line is immortal and able to produce specific antibodies

    KOHLER, MILSTEIN, JERNE

  • 2

    Exhibit purity and specificity able to recognized and bind to a specific antigen

    MONOCLONAL ANTIBODIES

  • 3

    Purified antibodies cloned from a single cell

    MONOCLONAL ANTIBODIES

  • 4

    fusion of two different types of cells

    HYBRIDOMA

  • 5

    cancerous plasma cells that annot make their own DNA. They will die out unless they are fused to a plasma cell

    MYELOMA CELL

  • 6

    Myeloma cell is deficiency of the enzyme:

    HYPOXANTHINE GUANINE PHOSPHORIBOSYL TRANSFERASE

  • 7

    Immunoglobulins derived from a single clone of cells

    MONOCLONAL ANTIBODIES

  • 8

    an antibody directed against HER-2 or the neu protein, which is present in large numbers on tumor cells, has been helpful in slowing the disease’s progress

    HERCEPTIN

  • 9

    Tightly linked clusters of genes that Participates in the development of HMI and CMI

    MAJOR HISTOCOMPATIBILITY COMPLEX

  • 10

    Partly determines response of an individual to antigens of infectious disease and graft rejection. Implicated in susceptibility to disease and development of autoimmunity

    MAJOR HISTOCOMPATIBILITY COMPLEX

  • 11

    MAJOR HISTOCOMPATIBILITY COMPLEX First named as

    HUMAN LEUKOCYTE ANTIGEN

  • 12

    he observes MHC in responses of the specific white blood cells

    DAUSSET

  • 13

    It is named major histocompatibility complex because they determine whether a transplanted tissue is

    HISTOCOMPATIBLE

  • 14

    Coded for three different loci Highest on lymphocytes but Low or undetected on liver, neural cells, muscle cells and sperm

    CLASS I MOLECULE

  • 15

    locations where alleles are present

    LOCI

  • 16

    alternative form of a gene that is found on the same chromosome

    ALLELE

  • 17

    CLASS I MOLECULE Chain structure

    A CHAIN, B2 MICROGLOBULIN

  • 18

    are not detected, or low in production in the liver, which is why it is a common form of transplant.

    CLASS I MOLECULE

  • 19

    Mainly found in ANTIGEN PRESENTING CELL Presents processed antigenic peptides to Th Cells

    CLASS II MOLECULE

  • 20

    CLASS II MHC MOLECULE  CODED FOR SEVERAL LOCI o It includes

    DR, DQ, DP

  • 21

    CLASS II MHC MOLECULE chain structure

    A CHAIN, B CHAIN

  • 22

    will lead to the destruction of the antigen

    CLASA I MOLECULE

  • 23

    will lead to production of antibodies and antigen via plasma cells and memory b cells

    CLASS II MOLECULE

  • 24

    Encodes for components of the complement system and inflammation

    CLASS III MOLECULE

  • 25

    Secreted proteins that have immune function but are expressed on cell surface

    CLASS III MOLECULE

  • 26

    least immunogenic because cornea is the most privilege site {not easily recognize by the immune system)

    CORNEA

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    SUBCUTANEOUS FUNGI

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    SYSTEMIC FUNGI

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    MEGAKARYOPOIESIS

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    HEMATOPOIESIS

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    LEUKOPOIESIS MCQ

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    LEUKOPOIESIS II AND MONOPOIESIS MCQ

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    MEGAKARYOPOIESIS MCQ

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    BLOOD COLLECTION

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    LABORATORY SAFETY

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    LABORATORY 1

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    LABORATORY 3

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    DEMATIACEOUS OPPORTUNISTIC FUNGI

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    PENICILLUS

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    HEMOCYTOMETRY

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    HEMOGLOBIN

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    HEMOGLOBIN PART 2

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    OXYGEN DISSOCIATION CURVE

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    QUANTIFICATION OF HBF

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