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  • Jef Marc Valencia

    • 問題数 49 • 3/12/2024

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  • 1

    THE PROCESS BY WHICH AN RNA SEQUENCE IS FORMED FROM A DNA TEMPLATE.

    TRANSCRIPTION

  • 2

    TRANSCRIPTION SEQUENCE

    DNA, RNA, CHON SYNTHESIS

  • 3

    UNLIKE IN IN REPLICATION, TRANSCRIPTION HAPPENS ON

    ONE STRAND

  • 4

    MAJOR STEPS TRANSCRIPTION

    INITIATION, ELONGATION, TERMINATION

  • 5

    THE TRANSCRIPTION COMPLEMENTARY STRANDS:

    TEMPLATE STRAND, CODING STRAND

  • 6

    ✓USED FOR RNA SYNTHESIS ✓A.K.A ANTISENSE STRAND

    TEMPLATE STRAND

  • 7

    ✓HAS THE SAME SEQUENCE AS THE RNA PRODUCED, WITH THE EXCEPTION OF ONE NITROGENOUS BASE PAIR. ✓NON-TEMPLATE STRAND

    CODING STRAND

  • 8

    ✓A.K.A SENSE STRAND

    CODING STRAND

  • 9

    THE PRODUCT PRODUCED BY TRANSCRIPTION.

    mRNA

  • 10

    ALL RNA CAN BE PRODUCED ON THE

    DNA STRAND

  • 11

    WHETHER REPLICATION OR TRANSCRIPTION, THE DIRECTION IS ALWAYS

    5-3

  • 12

    WHEN THE SYNTHESIS IS 5’ TO 3’, THE TEMPLATE STRAND IS

    3-5

  • 13

    ENZYMES BINDS TO A PROMOTER SITE OF THE DNA.

    RNA POLYMERASE II

  • 14

    RNA POLYMERASE PULLS A PORTION OF THE DNA STRANDS APART FROM EACH OTHER, EXPOSING

    UNATTACHED DNA BASES

  • 15

    ONE OF THE TWO DNA STRANDS PROVIDES THE TEMPLATE FOR THE SEQUENCE OF THE mRNA NUCLEOTIDES Term as

    ANTISENSE VS. SENSE

  • 16

    THE RNA IS SYNTHESIZED ONLY IN _DIRECTION.

    5-3

  • 17

    RNA POLYMERASE MOVES IN _DIRECTION

    3-5

  • 18

    ALONG THE DNA TEMPLATE STRAND WHILE ASSEMBLING THE mRNA STRAND FROM _

    5-3

  • 19

    SEPARATE FROM THE TRANSCRIBED SINGLE mRNA STRAND.

    DNA STRAND, RNA POLYMERASE

  • 20

    THE TRANSCRIPTION MECHANISM FINAL PRODUCT

    PRIMARY TRANSCRIPT

  • 21

    APPLIED TO THE PRIMARY mRNA MOLECULE BEFORE IT LEAVES THE NUCLEUS.

    POST TRANSCRIPTION MODIFICATION

  • 22

    RNA PRODUCTS ARE NOT NECESSARILY

    FUNCTIONAL

  • 23

    POST-TRANSCRIPTION MODIFICATION EXAMPLES;

    SPLICING, CAPPING, POLYADENYLATION

  • 24

    INTRONS IN THE PRECURSOR mRNA ARE EXCISED AND THE EXONS ARE SPLICED TOGETHER TO FORM A SHORTER MATURE mRNA.

    SPLICING

  • 25

    5’ END OF RNA IS CAPPED BY THE ADDITION OF A METHYLATED GUANINE NUCLEOTIDE.

    CAPPING

  • 26

    3’ END ACQUIRES A poly(A) TAIL THAT CONTAINS APPROX. 200 ADENINE RESIDUES.

    POLYADENYLATION

  • 27

    CAPPING: 5’ END OF RNA IS CAPPED BY THE ADDITION OF

    METHYLATED GUANINE NUCLEOTIDE

  • 28

    THE MAIN TRANSCRIPTION ENZYME

    RNA POLYMERASE

  • 29

    RNA POLYMERASE BINDS TO A_NEAR THE BEGINNING OF A GENE

    PROMOTER SEQUENCE

  • 30

    DNA UNWINDING FORMS

    TRANSCRIPTION BUBBLE

  • 31

    THE SITE FROM WHICH THE FIRST RNA NUCLEOTIDE IS TRANSCRIBED IS CALLED

    +1 SITE

  • 32

    RNA POLYMERASE BINDS TO THE PROMOTER REGION OF THE GENE OF INTEREST.

    INITIATION

  • 33

    THE PROMOTER INDICATES WHERE TRANSCRIBING SHOULD BEGIN.

    INITIATION

  • 34

    TRANSCRIPTION BUBBLE IS FORMED ➔ TRANSCRIPTION INITIATES.

    INITIATION

  • 35

    INDICATES WHERE TRANSCRIBING SHOULD BEGIN

    PROMOTER

  • 36

    STAGE WHERE THE RNA GETS LONGERS DUE TO NUCLEOTIDE SYNTHESIS.

    ELONGATION

  • 37

    RNA POLYMERASE MOVES AT A 3’ TO 5’ DIRECTION ALONG THE TEMPLATE STRAND AND THE mRNA MOVES AT AN OPPOSITE DIRECTION.

    ELONGATION

  • 38

    THE RNA TRANSCRIPT IS ALMOST AN IDENTICAL COPY OF THE SENSE CODING STRAND BUT T → U

    ELONGATION

  • 39

    RNA POLYMERASE WILL KEEP TRANSCRIBING UNTIL IT RECEIVES AS SIGNAL OR MARKER TO HALT.

    TERMINATION

  • 40

    THE SIGNAL: TERMINATOR—A SEQUENCE OF DNA.

    TERMINATION

  • 41

    SEQUENCE OF DNA SIGNAL:

    TERMINATOR

  • 42

    TERMINATION IN BACTERIA

    Rho DEPENDENT VS. Rho INDEPENDENT

  • 43

    RNA HAS A BINDING SIDE FOR THE Rho CHON. Rho BINDS TO THE SITE AND WORKS ITS WAY UP THE TRANSCRIPT TO THE POLYMERASE IN THE TRANSCRIPTION BUBBLE. WHEN IT DOES, IT ‘UNZIPS’ THE RNA TRANSCRIPT FROM THE TEMPLATE DNA, ENDING THE TRANSCRIPTION

    DEPENDENT

  • 44

    A SPECIFIC ENDING REGION IN C AND G NICLEOTIDES WILL TRIGGER THE RNA TRANSCRIPT TO FOLD ITSELF IN A ‘HAIRPIN’ FORMATION, ENDING THE TRANSCRIPTION.

    INDEPENDENT

  • 45

    area of transcription, where the two strands separate

    TRANSCRIPTION BUBBLE

  • 46

    Adenosine monophosphate is used; for stabilization against enzymatic breakdown

    POLYADENYLATION

  • 47

    first synthesized nucleotide; succeeding nucleotides are negative; movement is downstream

    INITIATION SITE

  • 48

    Typical bacterial initiation site start at _ because

    10-35, ADENINE, THYMINE

  • 49

    help RNA polymerase to bind to promoter site

    BASAL

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    DRUG OF ABUSE

    問題数 952025/07/13

    TOXINS

    問題数 572025/07/13

    TDM

    問題数 942025/07/13

    ENDOCRINOLOGY

    問題数 962025/07/16

    ENDROCRINOLOGY PART 2

    問題数 462025/07/16

    FACTORS AFFECTING ENZYME ACTIVITY-MCQ

    問題数 892025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ

    問題数 992025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ2

    問題数 872025/07/18

    MEDICAL TERMINOLOGIES

    問題数 362025/08/17

    INTRODUCTION TO HEMA 1

    問題数 292025/08/17

    LABORATORY SAFETY

    問題数 232025/08/18

    TERMINOLOGIES

    問題数 512025/08/21

    LABORATORY 1

    問題数 182025/08/22

    LABORATORY 3

    問題数 532025/08/22

    HEMATOPOIESIS

    問題数 622025/08/23

    THEORIES ON BLOOD FORMATION

    問題数 552025/08/30

    ERYTHROPOIESIS

    問題数 462025/08/30

    LEUKOPOIESIS

    問題数 1002025/08/30

    LEUKOPOIESIS II AND MONOPOIESIS

    問題数 422025/09/01

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/24

    MYCOLOGY PROPER

    問題数 712025/09/01

    FUNGAL PATHOGENESIS

    問題数 352025/09/01

    CLASSIFICATION OF FUNGI

    問題数 452025/09/06

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS

    問題数 742025/09/06

    MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 542025/09/06

    Mind mapping

    問題数 92025/09/07

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/13

    MYCOLOGY PROPER MCQ

    問題数 592025/09/13

    FUNGAL PATHOGENESIS MCQ

    問題数 372025/09/13

    CLASSIFICATION OF FUNGI MCQ

    問題数 332025/09/13

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS MCQ

    問題数 742025/09/13

    MCQ-MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 532025/09/14

    THE SUPEFICIAL FUNGI

    問題数 342025/09/12

    THE CUTANEOUS FUNGI

    問題数 582025/09/13

    SUBCUTANEOUS FUNGI

    問題数 552025/09/13

    SYSTEMIC FUNGI

    問題数 282025/09/13

    LYMPHOPOIESIS

    問題数 442025/09/07

    MEGAKARYOPOIESIS

    問題数 342025/09/07

    INTRODUCTION TO HEMA1 MCQ

    問題数 452025/09/10

    HEMATOPOIESIS

    問題数 582025/09/14

    THEORIES ON BLOOD FORMATION

    問題数 462025/09/14

    ERYTHROPOIESIS MCQ

    問題数 412025/09/14

    LEUKOPOIESIS MCQ

    問題数 942025/09/10

    LEUKOPOIESIS II AND MONOPOIESIS MCQ

    問題数 392025/09/14

    LYMPHOPOIESIS MCQ

    問題数 392025/09/10

    MEGAKARYOPOIESIS MCQ

    問題数 392025/09/10

    BLOOD COLLECTION

    問題数 352025/09/10

    LABORATORY SAFETY

    問題数 212025/09/17

    LABORATORY 1

    問題数 162025/09/17

    LABORATORY 3

    問題数 472025/09/17

    BLOOD COLLECTION MCQ

    問題数 792025/09/17

    DEMATIACEOUS OPPORTUNISTIC FUNGI

    問題数 522025/09/30

    PENICILLUS

    問題数 212025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA IN CLUSTER

    問題数 162025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA BORNE SINGLY

    問題数 122025/10/08

    ZYGOMYCETE/HYALINE SEPTATE GROUP

    問題数 492025/10/08

    YEAST AND YEAST LIKE ORGANISMS

    問題数 722025/10/15

    HEMOCYTOMETRY

    問題数 832025/10/03

    HEMOGLOBIN

    問題数 1002025/10/04

    HEMOGLOBIN PART 2

    問題数 262025/10/05

    OXYGEN DISSOCIATION CURVE

    問題数 282025/10/14

    QUANTIFICATION OF HBF

    問題数 762025/10/12

    YEAST AND YEAST LIKE ORGANISMS

    問題数 702025/10/26