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1
Classifications of Renal Dx
GLOMERULAR, INTERSTITIAL, TUBULAR
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Most c'mon class of Renal Disorder caused by immune mediation (bacteria, pathogens)
GLOMERULAR
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Class of Renal Disorders caused by toxic substances and infections
TUBULAR
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Class of Renal Disorder caused by medications
INTERSTITIAL
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Refers to a sterile inflammatory process that affects the glomerulus and is associated w/ the finding of blood, protein, and casts in the urine
GLOMERULONEPHRITIS
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Majority of Glomerular disorder are caused by
IMMUNE ORIGIN
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Class of Glomerular Disorder
NEPHROTIC SYNDROME, NEPHRITIC SYNDROME
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Class of Glomerular disorder which is immune mediated and acute onset of usually gross visible hematuria
NEPHRITIC SYNDROME
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C'mon findings of Nephritic syndrome
RBC CAST, HEMATURIA, MILD-MODERATE PROTEINURIA, OLIGURIA, HYPERTENSION
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Class of Glomerular Disorder caused by the disruption electrical charges of the basement membranes leading to massive loss of proteins and lipids. It can also be chronic or acute
NEPHROTIC SYNDROME
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C'mon findings of Nephrotic syndrome
HEAVY PROTEINURIA, HEMATURIA, RENAL TUBULAR CELL, OVAL FAT BODY, FAT DROPLET, FATTY/WAXY CAST
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Deposition of immune complexes formed in conjunction of Group A streptococcus infection on the glomerular membrane. Renal Disorder Class
ACUTE POSTSTREPTOCOCCAL GLOMERULONEPHRITIS, NEPHRITIC
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Protein that is pathogenic to man caused by the Group Streptococcus
M PROTEIN
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Appearance of RBCs seen in Acute post streptococcal Glomerulonephritis due to the proliferation of Blood
DYSMORPHIC
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Test to confirm acute post streptoccocal glomerulonephritis infection
ANTI STREPTOLYSIN O TITER
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Deposition of immune complexes from systemic immune disorders such as Systemic Lupus Erythematosus on the Glomerular membrane.Renal Disorder Class
RAPIDLY PROGRESSIVE (CRESCENTIC) GLOMERULONEPHRITIS, NEPHRITIC
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Cellular proliferation of epithelial cells inside the bowman's capsule from____in rapidly progressive glomerulonephritis
CRESCENT RBC
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Deposition of antiglomerular basement membrane antibody to glomerular and alveolar basement membrane.Renal Disorder Class
GOODPASTURE SYNDROME, NEPHRITIC
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What is detected in Henel biopsy confirming Goodpasture syndrome
ANTI GLOMERULAR BASEMENT MEMBRANE ANTIBODY
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Color of Anti GBM gio when detected
BRIGHT GREEN
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Disorder causing a granuloma producing inflammation of the small blood vessels of primarily the kidney and respiratory system.
WEGENERS GRANULOMATOSIS, GRANULOMATOSIS WITH POLYANGIITIS, NEPHRITIC
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Usually occurs in children following viral respiratory infections causing allergic purpura that causes decrease in the number of platelets and affects vascular integrity. Renal Disorder Class
HENOCH SCHONLEIN PURPURA, NEPHRITIC
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Antibody detected in the pxt. Serum during Wegeners Granulomatosis
ANTI NEUROPHILIC CYTOPLASMIC ANTIBODY
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Allergic rash that only affects small area of the skin
PURPURA
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The pronounced thickening of the glomerular basement membrane resulting from the deposition of immunoglobulin G immune complexes. Renal Disorder Class
MEMBRANOUS GLOMERULONEPHRITIS, NEPHRITIC
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Cellular proliferation affecting capillary walls of the glomerular basement membrane. Renal Disorder Class
MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS, NEPHRITIC
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Gradual worsening of symptoms leading to loss of kidney function leading to progression to end stage renal failure w/ Nephritic syndromes.
CHRONIC GLOMERULONEPHRITIS, NEPHRITIC
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The most c'mon cause of glomerulonephritis caused by IgA deposition on the glomerular membrane leading to thickening. Renal Disorder Class
BERGERS DISEASE, IMMUNOGLOBULIN A NEPHROPATHY, NEPHRITIC
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Genetic disorder primarily affecting men showing lamellated and thinning of Glomerular Basement Membrane. Renal Disorder Class
ALPORT SYNDROME, NEPHROTIC
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Disruption of podocytes occuring primarily in children following allergic reactions and immunizations causing little cellular changes. Renal Disorder Class
LIPID NEPHROSIS, MINIMAL CHANGE DISEASE, NEPHROTIC
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These are foot like processes found in the glomerulus which is affected during FSGS, and Minimal Change Disease
PODOCYTE
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Disruption of podocytes in certain areas of glomerulus but others remain normal due to heroin, analgesic abuse and AIDS. Renal Disorder Class
FOCAL SEGMENTAL GLOMERULOSCLEROSIS, NEPHROTIC
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The most c'mon cause of end stage renal disease due to increased proliferation of mesangial cells and deposition of cellular, non cellular materials, and glycosylated proteins on the GBM caused by poorly controlled blood glucose level. Renal Disorder Class
DIABETIC NEPHROPATHY, KIMMELSTIEL WILSON, NEPHROTIC
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Increased proliferation of mesangial cells during Diabetic Nephropathy may caused
KIMMELSTIEL WILSON NODULE
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Test to detect glycosylated proteins deposition in GBM during Diabetic Nephropathy
HbA1 C
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Expected urine output and color during Nephritic Syndrome
COLA COLORED, OLIGURIA
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Expected blood condition during Nephritic Syndrome
HYPERTENSION
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Expected Urine condition during Nephrotic Syndrome
HEAVY PROTEINURIA
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Expected blood condition during Nephrotic Syndrome
HYPOALBUMINEMIA
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Class of Renal disorders affecting the renal tubules include those in which tubular function is disrupted as a result of actual damage to the tubules which could be a metabolic or hereditary affecting the intricate functions of tubules.
TUBULAR
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Damage to the renal tubular epithelial cell due to ischemia and nephrotoxic agents. Renal Disorder Class
ACUTE TUBULAR NECROSIS, TUBULAR
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Most frequent tubular disorder caused by failure of tubular reabsorption in the PCT. It can also be associated w Cystinosis and Hartnup disease. Renal Disorder Class
FANCONIS SYNDROME, TUBULAR
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Refering to the accumulation of cystine
CYSTINOSIS
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Refering to the accumulation of tryptophan
HARTNUP DISEASE
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What are the substances no being reabsorbed in the PCT during Fanconis Syndrome
GLUCOSE, AMINO ACID, PHOSPHORUS, SODIUM, POTASSIUM, BICARBONATE, WATER
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Failure of the Hypothalamus to produce ADH. Renal Disorder Class
NEUROGENIC DIABETES INSIPIDUS, TUBULAR
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Renal tubules not responding to ADH. Renal Disorder Class
NEPHROGENIC DIABETES INSIPIDUS, TUBULAR
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Inherited defects in the production of uromodulin by the renal tubules which is replaced by abnormal forms destroying RTE cells.It also increase uric acid promoting gout. Renal Disorder Class
UROMODULIN ASSOCIATED KIDNEY DISEASE, TUBULAR
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A condition which increased urine glucose due t defective tubular absorption but pxt has a normal blood glucose. Renal Disorder Class
RENAL GLUCOSURIA, TUBULAR
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A renal disorder class affecting the interstitium affecting tubules due to their close proximity. These are majority caused by inflammation and infection.
TUBULOINTERSTITIAL
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Lower UTI c'mon to women and children due to bacterial infection of the urinary bladder. Renal Disorder Class
TUBULOINTERSTITIAL, CYSTITIS
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Upper UTI due to infection of the renal tubules and interstitium related to interference of urine flow to the bladder, reflux or urine from the bladder and untreated cystitis. Renal Disorder Class
ACUTE PYELONEPHRITIS, TUBULOINTERSTITIAL
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Recurrent infection of the renal tubules and interstitium caused by structural abnormalities affecting the flow of urine. Renal Disorder Class
CHRONIC PYELONEPHRITIS, TUBULOINTERSTITIAL
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Allergic Inflammation of the renal interstitium in response to certain medications. Renal Disorder Class
ACUTE INTERSTITIAL NEPHRITIS, TUBULOINTERSTITIAL
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Heavy proteinuriamay suggest if proteins goes in what level
>3.5 G/DAY
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Levels that may suggest decreased glomerular filtration rate
<25 ML/MIN
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General Characteristics of Renal Failure
AZOTEMIA, EDEMA, OLIGURIA, DECREASED GFR
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Gradual S/S chronic glomerulonephritis
OLIGURIA, EDEMA, HYPERTENSION, ANEMIA, FATIGUE, AZOTEMIA
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Damage by macrophages to the capillary walls releases cells and plasma into Bowman's space and the production of crescentic formation containing macrophages, fibroblasts, and polymerized fibrin causes permanent damage to the capillary tufts Disorder class:
RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS, NEPHRITIC
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Causes morphologic changes to the glomeruli resembling those in rapid progressive glomerulonephritis seen in conjunction with the autoimmune disorder Disorder class
GOODPASTURE SYNDROME, NEPHRITIC
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Leukocytes involved in Wegeners Granulomatosis
NEUTROPHILS
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Aside from allergic purpura seen in Henoch Schonlein purpura, What are the other s/s that may seen
BLOODY SPUTUM, BLOODY STOOL, BLOODY URINE
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Associated w/ diseases like SLE, Sjogren syndrome, secondary syphilis, hep B infection
MEMBRANOUS GLOMERULONEPHRITIS
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Disease associated to Hartnup and Cystinosis
FANCONI SYNDROME