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ENZYME OF CLINICAL SIGNIFICANCE-MCQ

  • Jef Marc Valencia

    • 問題数 99 • 7/17/2025

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  • 1

    EC 2.6.1.1

    AST

  • 2

    SGOT

    AST

  • 3

    Serves as an important biomarker for liver, muscle disorders, and cardiac events

    AST

  • 4

    Marker for the detection and monitoring of liver disease

    ALT

  • 5

    EC 2.6.1.2

    ALT

  • 6

    EC 2.7.3.2

    CK

  • 7

    EC 1.1.1.27

    LDH

  • 8

    An important oxidoreductase enzyme that catalyzes the interconversion of lactate and pyruvate

    LDH

  • 9

    EC 3.1.3.2

    ACP

  • 10

    A hydrolase enzyme tha catalyzes the hydrolysis of phosphate esters in acidic conditions

    ACP

  • 11

    EC 3.1.3.1

    ALP

  • 12

    Catalyzes the hydrolysis of phosphate groups from various molecules such as nucleotides proteins and alkaloids under alkaline conditions

    ALP

  • 13

    EC 2.3.2.1

    GGT

  • 14

    Catalyzes the transfer of y glutamyl group from y glutamyl peptides like glutathione

    GGT

  • 15

    Highest sensitivity for the detection of liver disorders

    GGT

  • 16

    Full name is A1, 1-4 glucan-4-glucanohydrolase

    AMS

  • 17

    EC 3.2.1.1

    AMS

  • 18

    Smallest enzyme which could easily pass through glomeruli

    AMS

  • 19

    Catalyzes the hydrolysis of triglycerides esters of long chain fatty acid

    LPS

  • 20

    EC 3.1.1.3

    LPS

  • 21

    Chemical name is Triaglycerol Acylhydrolase

    LPS

  • 22

    EC 3.4.21.4

    TRYP

  • 23

    AST-AMI Pre Peak Return

    6-8 HRS, 24 HRS, 3-5 DAY

  • 24

    CK-AMI Pre Peak Return

    4-8 HRS, 12-24 HRS, 2-3 DAY

  • 25

    LDH-AMI Pre Peak Return

    12-24 HRS, 2-3 DAY, 10-14 DAY

  • 26

    AMS-Pancreatitis Pre Peak Return

    7-12 HRS, 12-72 HRS, 3-5 DAY

  • 27

    LPS-Pancreatitis Pre Peak Return

    4-8 HRS, 24 HRS, 7-14 DAY

  • 28

    AST ULN Viral hep

    100X

  • 29

    AST ULN Cirrhosis

    4X

  • 30

    AST ULN Skeletal muscle disorder

    4-8X

  • 31

    De ritis ratio formula

    AST/ALT

  • 32

    De Ritis Ratio <1

    NORMAL, VIRAL HEP

  • 33

    De Ritis Ratio 1-2

    CHRONIC LIVER, CIRRHOSIS

  • 34

    De Ritis Ratio >2

    ALCOHOLIC HEP, HEP/CEL CARCINOMA

  • 35

    AST Stability

    3-4 DAY AT 4-8C

  • 36

    ALT Stability

    3-4 DAY AT 4 C

  • 37

    Assay for AST

    KARMEN METHOD

  • 38

    Assay for ALT

    LDH COUPLED METHOD

  • 39

    Substrate for AST

    MDH

  • 40

    Substrate for ALT

    LDH

  • 41

    Optimal pH for Karmen

    7.3-7.8

  • 42

    Hemolysis in AST may increase result

    15X

  • 43

    Obligate activator for CK

    MAGNESIUM

  • 44

    Molecular structure of CK

    DIMERIC, 40,000 D

  • 45

    CK complexed w/ Ig

    MACRO CK TYPE 1

  • 46

    CK composed of oligomeric CK MT

    MACRO CK TYPE 2

  • 47

    Macro CK found in Severe illness, malignancy, and liver disease

    TYPE 2

  • 48

    Macro CK found in ADA, Old indivs,and Chronic illness

    TYPE 1

  • 49

    Macro CK attach to IgG

    CK BB

  • 50

    Macro CK attach to IgA

    CK MM

  • 51

    Helpful in detecting reoccurence of MI

    CK MB

  • 52

    Which CK can be used as tumor marker potential;

    CK BB

  • 53

    Optimum pH for CK forward reaction

    9.0

  • 54

    Optimum pH for CK reverse reaction

    6.7

  • 55

    Forward reaction step for CK

    CK REACTION, PEP SYSTEM, LDH SYSTEM

  • 56

    Reverse reaction step for CK

    PRIMARY CK REACTION, HK SYSTEM, G6PD SYSTEM

  • 57

    Which reaction requires magnesium in CK

    FORWARD

  • 58

    Reference method for CK based on net charge and mobility

    ELECTROPHORESIS

  • 59

    High resolution separation based on affinity to charged resin

    ION EXCHANGE

  • 60

    CK determination which uses anti m or anti b

    IMMUNOINHIBITION

  • 61

    CK determination which uses mono or polyclonal ab detecting active and inactive form

    IMMUNOASSAY

  • 62

    CK band source of misID in hemodialysis pxt during electrophoresis

    CK 1

  • 63

    Can quantify CK MB mass concentration

    IMMUNOASSAY

  • 64

    May merge to CK MB

    CK MM

  • 65

    May co elute to CK MB

    CK BB

  • 66

    Can also co elute with CK mb

    MACRO CK

  • 67

    Optimum pH for oliver rosalki method

    6.8

  • 68

    LDH band used for detection of Pancreatitis

    3

  • 69

    LDu c'monly used measures NANDH formed less product inhibition

    WACKER

  • 70

    2x faster used in dry slide tech requiring less specimen

    WROBLEUSKI LA DUE

  • 71

    LDH forward reaction

    8.8-9.8

  • 72

    LDH reverse reaction

    7.4-7.8

  • 73

    Wrobleuski la due pH

    7.2

  • 74

    Increases in mild hepatic injury

    cAST

  • 75

    Increases in severe hepatic injury

    mAST

  • 76

    Serves as rapid energy reserve capable of regenerating ATP from ADP during muscle contraction

    PHOSPHOCREATINE

  • 77

    May constitute 15% of total CK activity of the heart

    CK-Mt

  • 78

    Condition may elevate CK for up to 50X ULN

    DMD

  • 79

    Caused by the reduced cerebral blood flow due to throbotic or amblic stroke

    CEREBRAL ISCHEMIA

  • 80

    This leads to neuronal necrosis and CK BB leakage into CSF and occasionally serum

    CELLULAR HYPOXIA

  • 81

    Encompasses ischemic stroke intracerebral hemorrhage and subarachnoid hemorrhage

    ACUTE CEREBRAVASCULAR DISEASE

  • 82

    Acute metabolic encelopathy in chlidren following viral illness and aspirin use

    REYES SYNDROME

  • 83

    What ck elevates in Reyes syndrome

    CK BB, CK MM

  • 84

    This step is spectrochemically monitored by measruing the decrease in NADH absorbance at 340 nm

    FORWARD, LDH SYSTEM

  • 85

    This prevents equilibrium build up and maintains the forward flow of the CK reaction

    REVERSE, HK SYSTEM

  • 86

    NADPH is formed and measured spectrochemically at 340 nm

    REVERSE, G6PD SYSTEM

  • 87

    Enzyme ubiquitous in nature

    LDH

  • 88

    Molecular structure of LDH

    TETRAMER

  • 89

    Signifies grave prognosis and impending death

    LDH 6

  • 90

    Substrate to enhance LDH 1

    A HYDROXYBUTYRATE

  • 91

    Hemolysis may increase result of LDH for

    100-150X

  • 92

    Heat labile LDH

    1, 2

  • 93

    Heat stable LDH

    4, 5

  • 94

    Most unstable LDH

    5

  • 95

    Optimum pH of ACP

    5.0

  • 96

    Which ACP is prostatic tissue and tartrate sensitive

    1

  • 97

    Which ACP is granulocyte minor contributor

    2, 4

  • 98

    Which ACP is Plateles Rbcs, and monocytes; a major isoenzyme in plasma

    3

  • 99

    TRAP Bone ACP

    5

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    問題数 882025/05/03

    MCQ-AMNIOTIC FLUID

    問題数 732025/05/08

    HEMOFLAGELLATES

    問題数 682025/05/04

    Sex disorder

    問題数 602025/05/05

    NEMATODES

    問題数 62025/05/06

    MCQ-PERICARDIAL FLUID

    問題数 592025/05/11

    PHASMID NEMATODES

    問題数 52025/05/06

    HOOKWORMS

    問題数 92025/05/06

    MCQ-CSF

    問題数 942025/05/03

    BLOOD AND TISSUE NEMATODE

    問題数 82025/05/06

    PLATYHELMINTHS

    問題数 132025/05/06

    MCQ-CSF2

    問題数 242025/05/03

    TREMATODES

    問題数 72025/05/06

    INTRODUCTION

    問題数 362025/06/10

    INTRODUCTION TABLE

    問題数 412025/06/10

    CLASSFICATION OF ENZYME

    問題数 472025/06/11

    ENZYME VARIANTS

    問題数 412025/06/11

    FACTORS AFFECTING ENZYME ACTIVITY

    問題数 902025/06/12

    INTRODUCTION TO ENZYMOLOGY-MCQ

    問題数 412025/06/26

    CLASS AND VARIANT OF ENZYME-MCQ

    問題数 772025/06/26

    PITUITARY GLAND PART 2

    問題数 52025/07/04

    THYROID GLAND

    問題数 712025/07/04

    PARATHYROID GLAND

    問題数 122025/07/04

    ADRENAL GLAND

    問題数 772025/07/04

    SEX GLANDS

    問題数 352025/07/04

    OTHER GLANDS

    問題数 82025/07/04

    ACID BASE BALANCE

    問題数 512025/07/10

    TRACE ELEMENT

    問題数 792025/07/10

    VITAMINS

    問題数 272025/07/10

    TUMOR MARKERS

    問題数 252025/07/10

    TOXICOLOGY

    問題数 722025/07/13

    DRUG OF ABUSE

    問題数 952025/07/13

    TOXINS

    問題数 572025/07/13

    TDM

    問題数 942025/07/13

    ENDOCRINOLOGY

    問題数 962025/07/16

    ENDROCRINOLOGY PART 2

    問題数 462025/07/16

    FACTORS AFFECTING ENZYME ACTIVITY-MCQ

    問題数 892025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ2

    問題数 872025/07/18

    MEDICAL TERMINOLOGIES

    問題数 362025/08/17

    INTRODUCTION TO HEMA 1

    問題数 292025/08/17

    LABORATORY SAFETY

    問題数 232025/08/18

    TERMINOLOGIES

    問題数 512025/08/21

    LABORATORY 1

    問題数 182025/08/22

    LABORATORY 3

    問題数 532025/08/22

    HEMATOPOIESIS

    問題数 622025/08/23

    THEORIES ON BLOOD FORMATION

    問題数 552025/08/30

    ERYTHROPOIESIS

    問題数 462025/08/30

    LEUKOPOIESIS

    問題数 1002025/08/30

    LEUKOPOIESIS II AND MONOPOIESIS

    問題数 422025/09/01

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/24

    MYCOLOGY PROPER

    問題数 712025/09/01

    FUNGAL PATHOGENESIS

    問題数 352025/09/01

    CLASSIFICATION OF FUNGI

    問題数 452025/09/06

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS

    問題数 742025/09/06

    MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 542025/09/06

    Mind mapping

    問題数 92025/09/07

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/13

    MYCOLOGY PROPER MCQ

    問題数 592025/09/13

    FUNGAL PATHOGENESIS MCQ

    問題数 372025/09/13

    CLASSIFICATION OF FUNGI MCQ

    問題数 332025/09/13

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS MCQ

    問題数 742025/09/13

    MCQ-MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 532025/09/14

    THE SUPEFICIAL FUNGI

    問題数 342025/09/12

    THE CUTANEOUS FUNGI

    問題数 582025/09/13

    SUBCUTANEOUS FUNGI

    問題数 552025/09/13

    SYSTEMIC FUNGI

    問題数 282025/09/13

    LYMPHOPOIESIS

    問題数 442025/09/07

    MEGAKARYOPOIESIS

    問題数 342025/09/07

    INTRODUCTION TO HEMA1 MCQ

    問題数 452025/09/10

    HEMATOPOIESIS

    問題数 582025/09/14

    THEORIES ON BLOOD FORMATION

    問題数 462025/09/14

    ERYTHROPOIESIS MCQ

    問題数 412025/09/14

    LEUKOPOIESIS MCQ

    問題数 942025/09/10

    LEUKOPOIESIS II AND MONOPOIESIS MCQ

    問題数 392025/09/14

    LYMPHOPOIESIS MCQ

    問題数 392025/09/10

    MEGAKARYOPOIESIS MCQ

    問題数 392025/09/10

    BLOOD COLLECTION

    問題数 352025/09/10

    LABORATORY SAFETY

    問題数 212025/09/17

    LABORATORY 1

    問題数 162025/09/17

    LABORATORY 3

    問題数 472025/09/17

    BLOOD COLLECTION MCQ

    問題数 792025/09/17

    DEMATIACEOUS OPPORTUNISTIC FUNGI

    問題数 522025/09/30

    PENICILLUS

    問題数 212025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA IN CLUSTER

    問題数 162025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA BORNE SINGLY

    問題数 122025/10/08

    ZYGOMYCETE/HYALINE SEPTATE GROUP

    問題数 492025/10/08

    YEAST AND YEAST LIKE ORGANISMS

    問題数 722025/10/15

    HEMOCYTOMETRY

    問題数 832025/10/03

    HEMOGLOBIN

    問題数 1002025/10/04

    HEMOGLOBIN PART 2

    問題数 262025/10/05

    OXYGEN DISSOCIATION CURVE

    問題数 282025/10/14

    QUANTIFICATION OF HBF

    問題数 762025/10/12

    YEAST AND YEAST LIKE ORGANISMS

    問題数 702025/10/26