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THYROID GLAND

  • Jef Marc Valencia

    • 問題数 71 • 7/4/2025

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    問題一覧

  • 1

    Thyroid gland is located below the ____and consist of 2 broad lobes connected via____

    LARYNX, ISTHMUS

  • 2

    Thyroid gland is consists of secretory parts called___filled with hormone storing colloid known as _____. Each lobe is consists of about ____follicles

    FOLLICLE, THYROGLOBULIN, 20-40

  • 3

    T3 and T4 are from what cell

    FOLLICULAR CELL

  • 4

    What hormone is secreted in the parafollicular cells

    CALCITONIN

  • 5

    Lowers blood levels of calcium and phosphate by inhibiting bone resorption by osteoclasts and by accelerating uptake of calcium and phosphate into bone extracellular matrix

    CALCITONIN

  • 6

    Increase basal metabolic rate, stimulate synthesis of proteins, increase use of glucose and fatty acids for ATP production, increase lipolysis, enhance cholesterol secretion, accelerate body growth and contribute to development of the nervous system

    TRIIODOTHYRONINE, THYROXINE

  • 7

    Secretion of T3 and T4 is caused by: Stimulated by:

    THYROTROPIN RELEASING HORMONE, THYROID STIMULATING HORMONE

  • 8

    Steps in Thyroid hormone secretion

    IODIDE TRAPPING, SYNTHESIS OF THYROGLOBULIN, OXIDATION OF IODIDE, IODONIZATION OF TYROSINE, COUPLING OF T1 AND T2, PINOCYTOSIS AND DIGESTION OF COLLOID

  • 9

    Refers to Important action of Thyroid hormone which increases body temperature

    CALORIGENIC EFFECT

  • 10

    Important nutrient for thyroid hormone secretion

    IODINE

  • 11

    Refers to iodine being absorbed in the diet and transported to the follicular cells

    IODIDE TRAPPING

  • 12

    Refers to the step which iodide is synthesized in the rough ER allowing Golgi complex to package inside the secretory vesicles to be released into the lumen.

    SYNTHESIS OF THYROGLOBULIN

  • 13

    Packaging center of the cell

    GOLGI COMPLEX

  • 14

    Where protein is being synthesized inside the cell

    ROUGH ER

  • 15

    Refers to the step where iodide is converted to iodine

    OXIDATION OF IODIDE

  • 16

    Enzyme responsible for oxidation of iodide

    THYROID PEROXIDASE

  • 17

    Refers to the step where iodine will lodge to tyrosine found in the TGB can lodge to T1 and T2

    IODINATION OF TYROSINE

  • 18

    Refers to the step where thyroglobulin will fold allowing the coupling.

    COUPLING OF T1 AND T2

  • 19

    Triiodothyronine is product result from the coupling of

    DIIODOTHYRONINE, MONOIODOTHYRONINE

  • 20

    Thyroxine is product result from the coupling of

    DIIODOTHYRONINE

  • 21

    Main carrier protein of thyroid hormones accounting for 70-75%

    THYROXINE BINDING PROTEIN

  • 22

    Other carrier protein of thyroid hormone accounting for 10-25%

    THYROXINE BINDING PREALBUMIN

  • 23

    Other carrier protein of thyroid hormone accounting for 10% only

    THYROXINE BINDING ALBUMIN

  • 24

    Physiologically active thyroid hormone

    TRIIODOTHYRONINE

  • 25

    How many percent of free thyroid hormone if T4 99% is bound

    0.03%

  • 26

    How many percent of free thyroid hormone if T3 99.7% is bound

    0.3%

  • 27

    Process of converting T4 to t3

    MONODEIODINATION

  • 28

    Normal value for thyroid hormones T3: T4:

    7 UG/DL, 0.24 UG/DL

  • 29

    Biological function of Thyroid hormones

    INCREASE BASAL METABOLIC RATE, SYNTHESIS OF NA/K ATPASE , INCREASE BODY TEMPERATURE

  • 30

    Action of Thyroid hormones

    NEURAL DEVELOPMENT, SEXUAL MATURATION, INCREASE ADREGERGIC ACTIVITY, PROTEIN SYNTHESIS

  • 31

    Give the clinical condition: T4: Low T3: Low Free T4: Low TSH: High

    PRIMARY HYPOTHYROIDISM

  • 32

    Give the clinical condition: T4: Low T3: Low Free T4: Low TSH: Low

    SECONDARY HYPOTHYROIDISM

  • 33

    Give the clinical condition: T4: High T3: High Free T4: High TSH: Low

    PRIMARY HYPERTHYROIDISM

  • 34

    Give the clinical condition: T4: High T3: High Free T4: High TSH: High

    SECONDARY HYPERTHYROIDISM

  • 35

    Give the clinical condition: T4: Low T3: Low Free T4: Normal TSH:Normal

    PRIMARY DECREASED TBG

  • 36

    Give the clinical condition: T4: High T3: High Free T4: Normal TSH: Normal

    PRIMARY INCREASED TBG

  • 37

    FACTITIA

    FACTITIA

  • 38

    Most c'mon cause of hyperthyroidism caused by an autoimmune disorder leading to generalized overactivity of the thyroid gland

    GRAVES DISEASE

  • 39

    What gender is c'monly attacked by graves disease

    FEMALE

  • 40

    Causes of graves disease

    THYROTROPIN RECEPTOR ANTIBODY, THYROID STIMULATING IMMUNOGLOBULIN

  • 41

    S/S of graves disease characterized by inflamed tissues around the eye leading to bulging

    GRAVES OPHTALMOPATHY

  • 42

    Rare symptom of Graves disease where patients may develop lumpy reddish thickening of the skin

    PRETIBAL MYXEDEMA

  • 43

    Symptoms of graves disease due to elevated level of T3 and T4

    GOITER

  • 44

    Thyroid cant produce amount of hormones pituitary calls for normal

    PRIMARY HYPOTHYROIDISM

  • 45

    Thyroid isn't being stimulated by pituitary to produce hormones

    SECONDARY HYPOTHYROIDISM

  • 46

    Signs and symptoms of primary hypothyroidism

    FATIGUE, WEIGHT GAIN, DECREASED MENTAL AND PHYSICAL OUTPUT, COLD INTOLERANCE

  • 47

    Autoimmune disorder in which the immune system creates antibodies that damage the thyroid gland causing decreased output

    HASHIMOTOS DISEASE

  • 48

    Signs and symptoms of hashimotos disease

    COLD INTOLERANCE, PUFFY FACE, ENLARGEMENT OF TONGUE, PALE DRY SKIN, CONSTIPATION

  • 49

    Central thyroid disease causing serum decreased T3, T4, and TSH but could also normal.

    SECONDARY HYPOTHYROIDISM

  • 50

    Secondary hypothyroidism is caused by

    PITUITARY, HYPOTHALAMIC DISEASE

  • 51

    Normal functioning thyroid gland in the presence of an abnormal concetrations of TBG

    EUTHYROID

  • 52

    Most useful test for Thyroid gland

    THYROID STIMULATING HORMONE

  • 53

    Normal range in most laboratories for TSH

    0.5-5 MIU/L

  • 54

    Method of choice for TSH

    IMMUNOASSAY

  • 55

    Serum T3 and T4 is measured by

    RIA, CHEMILUMINOMETRIC ASSAY, ELISA

  • 56

    What thyroid protein should not be seen in serum for normal person

    THYROGLOBULIN

  • 57

    Synthesized and secreted exclusively by thyroid follicular cell which serves as a proof of residual thyroid tissue that could be benign or malignant

    THYROGLOBULIN

  • 58

    Ideal tumor marker for thyroid cancer patients

    THYROGLOBULIN

  • 59

    Thyroglobulin is measured via

    RIA, ELISA

  • 60

    Test to detect antibodies to TSH receptor

    THYROID AUTOIMMUNITY

  • 61

    Thyroid stimulating antibodies

    THYROID STIMULATING ANTIBODY, THYROID STIMULATING IMMUNOGLOBULIN

  • 62

    TSH receptor antibody

    TRAb, TSHR-Ab

  • 63

    Most accurate tool for thyroid nodules

    FINE NEEDLE ASPIRATION

  • 64

    Other tools for evaluation of the thyroid gland

    NUCLEAR MEDICINE, THYROID ULTRASOUND, FINE NEEDLE ASPIRATION

  • 65

    Nuclear Evaluation:

    NORMAL

  • 66

    Nuclear Evaluation:

    GRAVES DISEASE

  • 67

    Nuclear Evaluation:

    TOXIC MULTINODULAR GOITER

  • 68

    Nuclear Evaluation:

    TOXIC ADENOMA

  • 69

    Promotes Calcium deposition in bones and urinary exceretion lowering plasma calcium level.This opposes the effects of the parathyroid hormone acting primarily to increase the level calcium in the blood.

    CALCITONIN

  • 70

    Calcitonin is produced by what cell in the thyroid gland

    PARAFOLLICULAR CELL

  • 71

    Production of calcitonin is stimulated by

    HYPERCALCEMIA

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    問題数 792025/05/03

    PERICARDIAL FLUID

    問題数 662025/05/04

    MCQ-SPERM

    問題数 592025/05/03

    MCQ-SPERM 2

    問題数 882025/05/03

    MCQ-AMNIOTIC FLUID

    問題数 732025/05/08

    HEMOFLAGELLATES

    問題数 682025/05/04

    Sex disorder

    問題数 602025/05/05

    NEMATODES

    問題数 62025/05/06

    MCQ-PERICARDIAL FLUID

    問題数 592025/05/11

    PHASMID NEMATODES

    問題数 52025/05/06

    HOOKWORMS

    問題数 92025/05/06

    MCQ-CSF

    問題数 942025/05/03

    BLOOD AND TISSUE NEMATODE

    問題数 82025/05/06

    PLATYHELMINTHS

    問題数 132025/05/06

    MCQ-CSF2

    問題数 242025/05/03

    TREMATODES

    問題数 72025/05/06

    INTRODUCTION

    問題数 362025/06/10

    INTRODUCTION TABLE

    問題数 412025/06/10

    CLASSFICATION OF ENZYME

    問題数 472025/06/11

    ENZYME VARIANTS

    問題数 412025/06/11

    FACTORS AFFECTING ENZYME ACTIVITY

    問題数 902025/06/12

    INTRODUCTION TO ENZYMOLOGY-MCQ

    問題数 412025/06/26

    CLASS AND VARIANT OF ENZYME-MCQ

    問題数 772025/06/26

    PITUITARY GLAND PART 2

    問題数 52025/07/04

    PARATHYROID GLAND

    問題数 122025/07/04

    ADRENAL GLAND

    問題数 772025/07/04

    SEX GLANDS

    問題数 352025/07/04

    OTHER GLANDS

    問題数 82025/07/04

    ACID BASE BALANCE

    問題数 512025/07/10

    TRACE ELEMENT

    問題数 792025/07/10

    VITAMINS

    問題数 272025/07/10

    TUMOR MARKERS

    問題数 252025/07/10

    TOXICOLOGY

    問題数 722025/07/13

    DRUG OF ABUSE

    問題数 952025/07/13

    TOXINS

    問題数 572025/07/13

    TDM

    問題数 942025/07/13

    ENDOCRINOLOGY

    問題数 962025/07/16

    ENDROCRINOLOGY PART 2

    問題数 462025/07/16

    FACTORS AFFECTING ENZYME ACTIVITY-MCQ

    問題数 892025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ

    問題数 992025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ2

    問題数 872025/07/18

    MEDICAL TERMINOLOGIES

    問題数 362025/08/17

    INTRODUCTION TO HEMA 1

    問題数 292025/08/17

    LABORATORY SAFETY

    問題数 232025/08/18

    TERMINOLOGIES

    問題数 512025/08/21

    LABORATORY 1

    問題数 182025/08/22

    LABORATORY 3

    問題数 532025/08/22

    HEMATOPOIESIS

    問題数 622025/08/23

    THEORIES ON BLOOD FORMATION

    問題数 552025/08/30

    ERYTHROPOIESIS

    問題数 462025/08/30

    LEUKOPOIESIS

    問題数 1002025/08/30

    LEUKOPOIESIS II AND MONOPOIESIS

    問題数 422025/09/01

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/24

    MYCOLOGY PROPER

    問題数 712025/09/01

    FUNGAL PATHOGENESIS

    問題数 352025/09/01

    CLASSIFICATION OF FUNGI

    問題数 452025/09/06

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS

    問題数 742025/09/06

    MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 542025/09/06

    Mind mapping

    問題数 92025/09/07

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/13

    MYCOLOGY PROPER MCQ

    問題数 592025/09/13

    FUNGAL PATHOGENESIS MCQ

    問題数 372025/09/13

    CLASSIFICATION OF FUNGI MCQ

    問題数 332025/09/13

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS MCQ

    問題数 742025/09/13

    MCQ-MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 532025/09/14

    THE SUPEFICIAL FUNGI

    問題数 342025/09/12

    THE CUTANEOUS FUNGI

    問題数 582025/09/13

    SUBCUTANEOUS FUNGI

    問題数 552025/09/13

    SYSTEMIC FUNGI

    問題数 282025/09/13

    LYMPHOPOIESIS

    問題数 442025/09/07

    MEGAKARYOPOIESIS

    問題数 342025/09/07

    INTRODUCTION TO HEMA1 MCQ

    問題数 452025/09/10

    HEMATOPOIESIS

    問題数 582025/09/14

    THEORIES ON BLOOD FORMATION

    問題数 462025/09/14

    ERYTHROPOIESIS MCQ

    問題数 412025/09/14

    LEUKOPOIESIS MCQ

    問題数 942025/09/10

    LEUKOPOIESIS II AND MONOPOIESIS MCQ

    問題数 392025/09/14

    LYMPHOPOIESIS MCQ

    問題数 392025/09/10

    MEGAKARYOPOIESIS MCQ

    問題数 392025/09/10

    BLOOD COLLECTION

    問題数 352025/09/10

    LABORATORY SAFETY

    問題数 212025/09/17

    LABORATORY 1

    問題数 162025/09/17

    LABORATORY 3

    問題数 472025/09/17

    BLOOD COLLECTION MCQ

    問題数 792025/09/17

    DEMATIACEOUS OPPORTUNISTIC FUNGI

    問題数 522025/09/30

    PENICILLUS

    問題数 212025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA IN CLUSTER

    問題数 162025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA BORNE SINGLY

    問題数 122025/10/08

    ZYGOMYCETE/HYALINE SEPTATE GROUP

    問題数 492025/10/08

    YEAST AND YEAST LIKE ORGANISMS

    問題数 722025/10/15

    HEMOCYTOMETRY

    問題数 832025/10/03

    HEMOGLOBIN

    問題数 1002025/10/04

    HEMOGLOBIN PART 2

    問題数 262025/10/05

    OXYGEN DISSOCIATION CURVE

    問題数 282025/10/14

    QUANTIFICATION OF HBF

    問題数 762025/10/12

    YEAST AND YEAST LIKE ORGANISMS

    問題数 702025/10/26