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Sex disorder

  • Jef Marc Valencia

    • 問題数 60 • 5/5/2025

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  • 1

    A genetic condition in individuals assigned male at birth, involves an extra X chromosome (XXY instead of XY)

    KLINEFELTER SYNDROME

  • 2

    What chromosome is impaired in Klinefelter syndrome

    47,XXY

  • 3

    What chromosome variation is present in KIinefleter syndrome

    EXTRA CHROMOSOME X

  • 4

    What type of protein is affected in Klinefelter syndrome

    ALPHA 1 ANTITRYPSIN, CERULOPLASMIN

  • 5

    Give at least 5 s/s of klinefelter syndrome

    GYNECOMASTIA, ERECTILE DYSFUNCTION, INFERTILITY

  • 6

    Inheritance pattern of Klinefelter syndrome

    NOT INHERITED

  • 7

    Treatment available for Klinefelter syndrome

    TESTOSTERONE REPLACEMENT, FERTILITY TREATMENT, BREAST TISSUE SURGERY

  • 8

    XYY syndrome is also known as

    JACOBS SYNDROME

  • 9

    A rare genetic condition affecting males who have an extra Y chromosome in most or all of their cells

    XYY SYNDROME

  • 10

    Refers to only some cells carry the extra Y chromosome like in Jacobs syndrome

    MOSAICISM

  • 11

    Give at least 3 s/s of XYY syndrome

    HYPOTONIA, AUTISM, INVOLUNTARY MUSCLE MOVEMENT

  • 12

    Inheritance pattern of XYY syndrome

    NOT INHERITED

  • 13

    Available management for XYY syndrome

    THERAPY

  • 14

    A genetic disorder that affects only females and occurs when one of the two X chromosomes is either incomplete or missing

    TURNER SYNDROME

  • 15

    What chromosome is impaired in the Turner syndrome

    46,X

  • 16

    What type of protein is affected in turner syndrome

    STRUCTURAL, HORMONE RELATED, REGULATORY

  • 17

    Give at least 3 s/s of turner syndrome

    WEBBED NECK, PUFFINESS, INFERTILITY

  • 18

    Inheritance pattern of Turner syndrome

    NOT INHERITED

  • 19

    Available management for Turner syndrome

    GROWTH HORMONE THERAPY

  • 20

    referred to as Ovotesticular DSD (Disorder of sex development)

    HERMAPHRODITISM

  • 21

    a rare condition where a person is born with both ovarian (female) and testicular (male) gonadal tissue.

    HERMAPHRODITISM

  • 22

    Tissue might be separate (one ovary, one testis) or combined in one or both gonads

    OVOTESTIS

  • 23

    The most common scenario, seen in about 60% of individuals, is having in Hermaphroditism

    46,XX

  • 24

    Signal protein defected in Hermaphroditism

    RSPO1, WNT4

  • 25

    Transcription factor protein defected in hermaphroditism

    SRY, SOX9

  • 26

    Defective protein in hermaphroditism can lead to partial testicular development and ovotestis formation

    RSPO1

  • 27

    Defective protein in hermaphroditism that reduce ovary-promotingsignals, allowing some testicular tissue to form alongside ovarian tissue

    WNT4

  • 28

    Defective protein in hermaphroditism that can trigger partial testis/ovotestis formation.

    SRY

  • 29

    Defective protein in hermaphroditism that can disrupt normal gonad development, potentially leading to an ovotestis

    SOX9

  • 30

    Presence of Internal Female Structures in hermaphroditism

    MULLERIAN DERIVATIVE

  • 31

    Variable Internal Male Structures in hermaphroditism

    WOLFFIAN DUCT

  • 32

    Clinical manifestation of Hermaphroditism

    AMBIGUOUS GENITALIA AT BIRTH

  • 33

    Inheritance pattern of hermaphroditism if Not inherited and randomly de novo

    SPORADIC

  • 34

    Inheritance pattern of hermaphroditism if S0X9 duplication SRY gets translocated

    AUTOSOMAL DOMINANT

  • 35

    Inheritance pattern of hermaphroditism if RSPO1 is protein affected

    AUTOSOMAL RECESSIVE

  • 36

    Inheritance pattern of hermaphroditism if having mixed XX/XY cells is also typically a random event, Not inherited random errors in cell division

    MOSAICISM

  • 37

    Available management for Hermaphroditism

    GONADECTOMY, GENITAL SURGERY

  • 38

    Both ovarian and testicular tissue

    HERMAPHRODITISM

  • 39

    Gonads match one sex, but outer anatomy doesn’t

    PSEUDOHERMAPHRODITISM

  • 40

    Gene mutation involve in Male pseudohermaphroditism

    HSD17B3, SRD5A2, AR

  • 41

    Gene mutation in female pseudohermaphroditism

    CYP21A2

  • 42

    HSD17B3 gene mutation refers to

    DECREASE TESTOSTERONE SYNTHESIS

  • 43

    SRD5A2 gene mutation refers to

    DECREASE DHT PRODUCTION

  • 44

    AR gene mutation refers to

    ANDROGEN INSENSITIVITY

  • 45

    CYP21A2 gene mutation refers to

    EXCESS ANDROGEN IN CAH

  • 46

    Give at least 3 s/s of pseudohermaphroditism

    CRYPTORCHIDISM, CONGENITAL ADRENAL HYPERPLASIA, VIRILIZATION

  • 47

    Inheritance pattern of pseudohermaphroditism if Androgen Insensitivity Syndrome (AIS)

    X-LINKED RECESSIVE

  • 48

    Inheritance pattern of pseudohermaphroditism if Congenital Adrenal Hyperplasia (CAH) 5-alpha reductase deficiency (SRD5A2 mutations)

    AUTOSOMAL RECESSIVE

  • 49

    Inheritance pattern of pseudohermaphroditism if New mutations or chromosomal anomalies

    SPORADIC

  • 50

    Affected individuals are usually very tall. Many experience severe acne during adolescence. Additional symptoms may include learning disabilities and behavioral problems such as impulsivity.

    XYY SYNDROME

  • 51

    Intelligence is usually in the normal range, although IQ is on average ___points lower than siblings in XYY syndrome

    10-15

  • 52

    Turner syndrome chromosome

    45, X

  • 53

    Phenotypically female but are short in stature and do not exhibit sexual maturation.

    TURNERS SYNDROME

  • 54

    Intersex conditions are sometimes referred to as disorders

    DISORDER OF SEXUAL DEVELOPMENT

  • 55

    The condition of having both male and female reproductive organs.

    HERMAPHRODITISM

  • 56

    A condition in which the individual has a single chromosomal and gonadal sex but combines features of both sexes in the external genitalia causing doubt as to the true sex

    PSEUDOHERMAPHRODITISM

  • 57

    Refers to an individual with ovaries but with secondary sexual characteristics or external genitalia resembling those of a male

    FEMALE PSEUDOHERMAPHRODITISM

  • 58

    Also known as adrenogenital syndrome, is a common cause of female pseudohermaphroditis

    CONGENITAL ADRENAL HYPERPLASIA

  • 59

    Refers to individuals whose gonads are testes but whose secondary sexual characteristics or external genitalia resemble those of a female.

    MALE PSEUDOHERMAPHRODITISM

  • 60

    Male pseudohermaphroditism is rare and almost always results from

    AUTOSOMAL RECESSIVE

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    問題数 412025/06/26

    CLASS AND VARIANT OF ENZYME-MCQ

    問題数 772025/06/26

    PITUITARY GLAND PART 2

    問題数 52025/07/04

    THYROID GLAND

    問題数 712025/07/04

    PARATHYROID GLAND

    問題数 122025/07/04

    ADRENAL GLAND

    問題数 772025/07/04

    SEX GLANDS

    問題数 352025/07/04

    OTHER GLANDS

    問題数 82025/07/04

    ACID BASE BALANCE

    問題数 512025/07/10

    TRACE ELEMENT

    問題数 792025/07/10

    VITAMINS

    問題数 272025/07/10

    TUMOR MARKERS

    問題数 252025/07/10

    TOXICOLOGY

    問題数 722025/07/13

    DRUG OF ABUSE

    問題数 952025/07/13

    TOXINS

    問題数 572025/07/13

    TDM

    問題数 942025/07/13

    ENDOCRINOLOGY

    問題数 962025/07/16

    ENDROCRINOLOGY PART 2

    問題数 462025/07/16

    FACTORS AFFECTING ENZYME ACTIVITY-MCQ

    問題数 892025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ

    問題数 992025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ2

    問題数 872025/07/18

    MEDICAL TERMINOLOGIES

    問題数 362025/08/17

    INTRODUCTION TO HEMA 1

    問題数 292025/08/17

    LABORATORY SAFETY

    問題数 232025/08/18

    TERMINOLOGIES

    問題数 512025/08/21

    LABORATORY 1

    問題数 182025/08/22

    LABORATORY 3

    問題数 532025/08/22

    HEMATOPOIESIS

    問題数 622025/08/23

    THEORIES ON BLOOD FORMATION

    問題数 552025/08/30

    ERYTHROPOIESIS

    問題数 462025/08/30

    LEUKOPOIESIS

    問題数 1002025/08/30

    LEUKOPOIESIS II AND MONOPOIESIS

    問題数 422025/09/01

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/24

    MYCOLOGY PROPER

    問題数 712025/09/01

    FUNGAL PATHOGENESIS

    問題数 352025/09/01

    CLASSIFICATION OF FUNGI

    問題数 452025/09/06

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS

    問題数 742025/09/06

    MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 542025/09/06

    Mind mapping

    問題数 92025/09/07

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/13

    MYCOLOGY PROPER MCQ

    問題数 592025/09/13

    FUNGAL PATHOGENESIS MCQ

    問題数 372025/09/13

    CLASSIFICATION OF FUNGI MCQ

    問題数 332025/09/13

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS MCQ

    問題数 742025/09/13

    MCQ-MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 532025/09/14

    THE SUPEFICIAL FUNGI

    問題数 342025/09/12

    THE CUTANEOUS FUNGI

    問題数 582025/09/13

    SUBCUTANEOUS FUNGI

    問題数 552025/09/13

    SYSTEMIC FUNGI

    問題数 282025/09/13

    LYMPHOPOIESIS

    問題数 442025/09/07

    MEGAKARYOPOIESIS

    問題数 342025/09/07

    INTRODUCTION TO HEMA1 MCQ

    問題数 452025/09/10

    HEMATOPOIESIS

    問題数 582025/09/14

    THEORIES ON BLOOD FORMATION

    問題数 462025/09/14

    ERYTHROPOIESIS MCQ

    問題数 412025/09/14

    LEUKOPOIESIS MCQ

    問題数 942025/09/10

    LEUKOPOIESIS II AND MONOPOIESIS MCQ

    問題数 392025/09/14

    LYMPHOPOIESIS MCQ

    問題数 392025/09/10

    MEGAKARYOPOIESIS MCQ

    問題数 392025/09/10

    BLOOD COLLECTION

    問題数 352025/09/10

    LABORATORY SAFETY

    問題数 212025/09/17

    LABORATORY 1

    問題数 162025/09/17

    LABORATORY 3

    問題数 472025/09/17

    BLOOD COLLECTION MCQ

    問題数 792025/09/17

    DEMATIACEOUS OPPORTUNISTIC FUNGI

    問題数 522025/09/30

    PENICILLUS

    問題数 212025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA IN CLUSTER

    問題数 162025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA BORNE SINGLY

    問題数 122025/10/08

    ZYGOMYCETE/HYALINE SEPTATE GROUP

    問題数 492025/10/08

    YEAST AND YEAST LIKE ORGANISMS

    問題数 722025/10/15

    HEMOCYTOMETRY

    問題数 832025/10/03

    HEMOGLOBIN

    問題数 1002025/10/04

    HEMOGLOBIN PART 2

    問題数 262025/10/05

    OXYGEN DISSOCIATION CURVE

    問題数 282025/10/14

    QUANTIFICATION OF HBF

    問題数 762025/10/12

    YEAST AND YEAST LIKE ORGANISMS

    問題数 702025/10/26