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TDM

  • Jef Marc Valencia

    • 問題数 94 • 7/13/2025

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    問題一覧

  • 1

    Involves the analysis and evaluation of circulating concentrations of drugs in blood

    THERAPEUTIC DRUG MONITORING

  • 2

    This is to ensure that a given drug dosage which produces maximal therapeutic benefit and minimal toxic adverse effect

    THERAPEUTIC DRUG MONITORING

  • 3

    Consequences of over dosage

    TOXICITY

  • 4

    Consequences of under dosage

    TREATMENT FAILURE

  • 5

    The rate at which the drug is absorbed dependent upon th route of administration

    ABSORPTION

  • 6

    Transport mechanism of absorption

    PASSIVE DIFFUSION

  • 7

    Weak acids are absorbed in what organ

    STOMACH

  • 8

    Weak bases are absorbed in the

    INTESTINE

  • 9

    Single most important factor of TDM

    TIMING

  • 10

    Average peak concentrations of drug after an orallyy administered dose

    1 HOUR

  • 11

    Specimen of choice for TDM

    SERUM, PLASMA

  • 12

    C'monly used anticoagulant for TDM

    HEPARIN

  • 13

    What to avoid in sample collection for TDM

    HEMOLYSIS

  • 14

    Used to treat congestive heart failure and cardiac arrhythmias

    CARDIOTROPIC

  • 15

    Cardiotropic act on the ___of the cardiac muscle

    CONDUCTION SYSTEM

  • 16

    Net effect of cardiotropic

    SLOW DOWN ELECTRICAL CONDUCTION

  • 17

    Class of cardiotropic drug that blocks sodium channels during depolarization

    I

  • 18

    Class of cardiotropic drug that blocks blocks net effects of catecholamine

    II

  • 19

    Class of cardiotropic drug that works on atrial arrythmias

    III

  • 20

    Class of cardiotropic drug that blocks calcium channel blockers

    IV

  • 21

    Select all class 1 cardiotropics

    QUINIDINE, PROCAINAMIDE, LIDOCAINE, PHENYTOIN

  • 22

    Select all class 2 cardiotropics

    BETA ADRENERGIC BLOCKER, PROPRANOLOL

  • 23

    Select all class 3 cardiotropics

    POTASSIUM CHANNEL BLOCKER, AMIODARONE

  • 24

    Select all class 4 cardiotropics

    VERAPAMIL

  • 25

    Antibiotics used for the treatment of gram - bacterial infx

    AMINOGLYCOSIDE

  • 26

    Aminoglycosides are usually administered via

    INTRAMUSCULAR, INTRAVENOUS

  • 27

    Toxic effect of aminoglycosides

    NEPHROTOXICITY, OTOTOXICITY

  • 28

    Antibiotics used for the treatment of gram + cocci and bacilli

    VANCOMYCIN

  • 29

    Vancomycin administered by

    IV

  • 30

    Toxic therapeutic range of vancomycin

    5-10 UG/ML

  • 31

    Optimal blood sampling time of vancomycin

    TROUGH

  • 32

    Specific bacterias against vancomycin

    METHICILLIN RESISTANT S. AUREUS, S.PNEUMONIAE, ENTEROCOCCUS SPP

  • 33

    GIT bacteria against vancomycin

    C. DIFFICILE

  • 34

    Refers to damage to inner ear due to antibiotics toxicity

    OTOTOXICITY

  • 35

    Erythematous flushing of the extremities due to vancomycin toxicity

    RED MAN SYNDROME

  • 36

    2 major of types of seizure

    FOCAL/PARTIAL, GENERALIZED

  • 37

    Focal seizure which originates in one specific are of brain without loss of conciousness

    SIMPLE PARTIAL

  • 38

    Focal seizure which originates in one specific are of brain with loss of consciousness

    COMPLEX PARTIAL

  • 39

    Most well known generalized seizure

    GRAND MAL, TONIC CLONIC

  • 40

    Generalized seizure characterizes by blanking os mistakenluy identified as Day Dreaming

    ABSENCE, PETIT MAL

  • 41

    Generalized seizure focuses on muscle effect

    MYOCLONAL

  • 42

    Generalized seizure characterizes by sudden collapse

    ATONIC

  • 43

    Refers to muscle stiffness seizure

    TONIC

  • 44

    Refers to jerking seizure

    CLONIC

  • 45

    Anti seizure Used for generalized tonic-clonic seizure and simple partial seizure

    PHENOBARBITAL

  • 46

    Eye involvement toxicity due to phenobarbital

    NYSTAGMUS

  • 47

    Lack of eye and muscle coordination movement due to phenobarbital toxicity

    ATAXIA

  • 48

    Anti seizure for Short term prophylactic agent for brain injury

    PHENYTOIN

  • 49

    Major toxicity of phenytoin

    SEIZURE

  • 50

    Refers to abnormal hair growth due to phenytoin intoxicity

    HIRSUTISM

  • 51

    Long term toxicity effect of phenytoin

    VIT D AND FOLATE DEFICIENCY

  • 52

    Injectable water soluble pro-form phenytoin

    FOSPHENYTOIN

  • 53

    Anti seizure used for treatment of petit mal and absence seizure

    VALPROIC ACID

  • 54

    Valproic acid enhance the activity of ____mediated inhibitory system

    Y-AMINO BUTYRIC ACID

  • 55

    Hepatic dysfunction caused by the valproic acid

    HYPERAMMONEMIA

  • 56

    Which anti seizure drug causes terotogenic effect

    VALPROIC ACID

  • 57

    Toxicity of valproic acid causes

    SEDATION, GASTIC DISTURBANCE, ATAXIA

  • 58

    Anti seizure Used for generalized tonic clonic, simple partial, and complex partial seizure

    CARBAMAZEPINE

  • 59

    Refers to severe stabbingh pain in one side of face caused by carbamazepine

    TRIGEMINAL NEURALGIA, TIC DOULOUREX

  • 60

    Carbamazepine causes reduction of excitatory synaptic transmission in the__

    SPINAL TRIGEMINAL NUCLEUS

  • 61

    Metabolites of carbamazepine

    10, 11-EPOXIDE, 10, 11-DIHYDROXY

  • 62

    What anti seizure drug causes drowsiness, ataxia, dizziness, nausea and vomiting toxicity

    CARBAMAZEPINE

  • 63

    Rare toxicity of carbamazepine

    APLASTIC ANEMIA, THROMBOCYTOPENIA, AGRANULOCYTOSIS

  • 64

    Used for generalized tonic clonic, simple partial, and complex partial seizure

    PRIMIDONE, CARBAMAZEPINE

  • 65

    Metabolites of primidone

    PHENOBARBITAL, PHENYLETHYLMALONAMIDE

  • 66

    Anti seizure drug used for petit mal seizure which also chemically related to imipramine (TCA)

    ETHOSUXIMIDE

  • 67

    Chronic obstructive pulmonary disease caused by pulmonary or eosinophil obstruction characterizes by cough, chest tightness, and wheezing

    ASTHMA

  • 68

    First phase of Asthma

    BRONCHOCONSTRICTION

  • 69

    Second phase of Asthma

    INFLAMMATION

  • 70

    Broncho and vasodilator for moderate or severe asthma attacks

    THEOPHYLLINE

  • 71

    CNS stimulant which stimulates respiration and strengthens the action of cardiac muscles

    THEOPHYLLINE

  • 72

    Theophylline can be administered through

    ORAL, IV

  • 73

    Metabolite of theophylline

    3 METHYL XANTHINE

  • 74

    Drug that interacts with theophylline

    PHENYTOIN, CARBAMAZEPINE, ERYTHROMYCIN

  • 75

    Therapeutic range for Theophylline Adult: Newborn: Toxicity: Nausea, vomiting, headache, and anxiety Tachycardia, arrhythmias Seizure, Cardiac arrest

    10-20 UG/ML, 5-10 UG/ML, 15-20 UG/ML, 20-40 UG/ML, >40 UG/ML

  • 76

    Release and oxidize during tissue damage which medicines attacks

    ARACHIDONIC ACID

  • 77

    Inflammation pathway which asthma and allergy reactions occur

    LIPO OXYGENASE PATHWAY

  • 78

    Inflammatory mediator of lipo oxygenase pathway

    LEUKOTRIENE

  • 79

    Inflammation pathway which infection and injury occurs

    CYCLO OXYGENASE PATHWAY

  • 80

    Inflammatory mediator of cyclo oxygenase pathway

    THROMBOXANE, PROSTAGLANDIN

  • 81

    Anti inflammatory drug used to block cyclo oxygenase pathway also used to treat severe allergies and asthma

    CORTICOSTEROID

  • 82

    Anti inflammatory and pain reducer without undesirable effects

    NSAID

  • 83

    Analgesic, antipyretic and anti inflammatory used as anti thrombotic in lower dosage

    ASPIRIN

  • 84

    Metabolite of acetaminophen

    GLUCORONIDE, SULFATE CONJUGATE

  • 85

    Medications used to treat ADA and tissue transplant rejection

    IMMUNOSUPPRESIVE

  • 86

    Drug of choice for maintenance of kidney, liver, heart, and lung allografts

    CICLOSPORIN

  • 87

    Currently used in transplant surgery to prevent organ rejection which has similar toxicity profile to ciclosporin

    TACROLIMUS

  • 88

    Used to treat bipolar disease and depression

    MANIC DEPRESSION DRUG

  • 89

    Anti manic drug which is available as citrate and CO3 salt used to treat prophylaxis and treatment of bipolar disorder

    LITHIUM

  • 90

    Anti manic drug used to block reuptake and adrenergic and dopaminergic neurotransmitter

    TRICYCLIC ANTIDEPRESSANT

  • 91

    Chemotherapeutic agent used to inhibits dihydrofolate reductase-a cofactor of DNA synthesis

    METHOTREXATE

  • 92

    Chemotherapeutic agent Used to treat psoriasis, refractory rheumatoid arthritis, and malignant neoplastic disease

    METHOTREXATE

  • 93

    Chemotherapeutic agent used to treat leukemias and lymphomas prior to BM transplantation

    BUSULFAN

  • 94

    Toxicity of Busulfan

    HEPATIC VENO OCCLUSIVE DISEASE

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    問題数 242025/04/02

    TABULATED METABOLIC DISORDER

    問題数 192025/04/03

    FECAL ANALYSIS-MCQ

    問題数 862025/04/03

    BRISTOL STOOL CHART

    問題数 72025/04/03

    FECALYSIS CHEMICAL EXAMINATION

    問題数 512025/04/03

    BIOLOGICAL PREGNANCY TEST

    問題数 62025/03/31

    SPERM

    問題数 632025/04/22

    SPERM 2

    問題数 692025/04/22

    Fructose test table

    問題数 52025/04/22

    Sperm motility table

    問題数 82025/04/22

    PROTOZOAN

    問題数 812025/04/24

    CSF

    問題数 962025/04/29

    AMOEBA

    問題数 222025/04/29

    MCQ-CHEMICAL EXAMINATION OF URINE PART 2

    問題数 792025/05/03

    PERICARDIAL FLUID

    問題数 662025/05/04

    MCQ-SPERM

    問題数 592025/05/03

    MCQ-SPERM 2

    問題数 882025/05/03

    MCQ-AMNIOTIC FLUID

    問題数 732025/05/08

    HEMOFLAGELLATES

    問題数 682025/05/04

    Sex disorder

    問題数 602025/05/05

    NEMATODES

    問題数 62025/05/06

    MCQ-PERICARDIAL FLUID

    問題数 592025/05/11

    PHASMID NEMATODES

    問題数 52025/05/06

    HOOKWORMS

    問題数 92025/05/06

    MCQ-CSF

    問題数 942025/05/03

    BLOOD AND TISSUE NEMATODE

    問題数 82025/05/06

    PLATYHELMINTHS

    問題数 132025/05/06

    MCQ-CSF2

    問題数 242025/05/03

    TREMATODES

    問題数 72025/05/06

    INTRODUCTION

    問題数 362025/06/10

    INTRODUCTION TABLE

    問題数 412025/06/10

    CLASSFICATION OF ENZYME

    問題数 472025/06/11

    ENZYME VARIANTS

    問題数 412025/06/11

    FACTORS AFFECTING ENZYME ACTIVITY

    問題数 902025/06/12

    INTRODUCTION TO ENZYMOLOGY-MCQ

    問題数 412025/06/26

    CLASS AND VARIANT OF ENZYME-MCQ

    問題数 772025/06/26

    PITUITARY GLAND PART 2

    問題数 52025/07/04

    THYROID GLAND

    問題数 712025/07/04

    PARATHYROID GLAND

    問題数 122025/07/04

    ADRENAL GLAND

    問題数 772025/07/04

    SEX GLANDS

    問題数 352025/07/04

    OTHER GLANDS

    問題数 82025/07/04

    ACID BASE BALANCE

    問題数 512025/07/10

    TRACE ELEMENT

    問題数 792025/07/10

    VITAMINS

    問題数 272025/07/10

    TUMOR MARKERS

    問題数 252025/07/10

    TOXICOLOGY

    問題数 722025/07/13

    DRUG OF ABUSE

    問題数 952025/07/13

    TOXINS

    問題数 572025/07/13

    ENDOCRINOLOGY

    問題数 962025/07/16

    ENDROCRINOLOGY PART 2

    問題数 462025/07/16

    FACTORS AFFECTING ENZYME ACTIVITY-MCQ

    問題数 892025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ

    問題数 992025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ2

    問題数 872025/07/18

    MEDICAL TERMINOLOGIES

    問題数 362025/08/17

    INTRODUCTION TO HEMA 1

    問題数 292025/08/17

    LABORATORY SAFETY

    問題数 232025/08/18

    TERMINOLOGIES

    問題数 512025/08/21

    LABORATORY 1

    問題数 182025/08/22

    LABORATORY 3

    問題数 532025/08/22

    HEMATOPOIESIS

    問題数 622025/08/23

    THEORIES ON BLOOD FORMATION

    問題数 552025/08/30

    ERYTHROPOIESIS

    問題数 462025/08/30

    LEUKOPOIESIS

    問題数 1002025/08/30

    LEUKOPOIESIS II AND MONOPOIESIS

    問題数 422025/09/01

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/24

    MYCOLOGY PROPER

    問題数 712025/09/01

    FUNGAL PATHOGENESIS

    問題数 352025/09/01

    CLASSIFICATION OF FUNGI

    問題数 452025/09/06

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS

    問題数 742025/09/06

    MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 542025/09/06

    Mind mapping

    問題数 92025/09/07

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/13

    MYCOLOGY PROPER MCQ

    問題数 592025/09/13

    FUNGAL PATHOGENESIS MCQ

    問題数 372025/09/13

    CLASSIFICATION OF FUNGI MCQ

    問題数 332025/09/13

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS MCQ

    問題数 742025/09/13

    MCQ-MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 532025/09/14

    THE SUPEFICIAL FUNGI

    問題数 342025/09/12

    THE CUTANEOUS FUNGI

    問題数 582025/09/13

    SUBCUTANEOUS FUNGI

    問題数 552025/09/13

    SYSTEMIC FUNGI

    問題数 282025/09/13

    LYMPHOPOIESIS

    問題数 442025/09/07

    MEGAKARYOPOIESIS

    問題数 342025/09/07

    INTRODUCTION TO HEMA1 MCQ

    問題数 452025/09/10

    HEMATOPOIESIS

    問題数 582025/09/14

    THEORIES ON BLOOD FORMATION

    問題数 462025/09/14

    ERYTHROPOIESIS MCQ

    問題数 412025/09/14

    LEUKOPOIESIS MCQ

    問題数 942025/09/10

    LEUKOPOIESIS II AND MONOPOIESIS MCQ

    問題数 392025/09/14

    LYMPHOPOIESIS MCQ

    問題数 392025/09/10

    MEGAKARYOPOIESIS MCQ

    問題数 392025/09/10

    BLOOD COLLECTION

    問題数 352025/09/10

    LABORATORY SAFETY

    問題数 212025/09/17

    LABORATORY 1

    問題数 162025/09/17

    LABORATORY 3

    問題数 472025/09/17

    BLOOD COLLECTION MCQ

    問題数 792025/09/17

    DEMATIACEOUS OPPORTUNISTIC FUNGI

    問題数 522025/09/30

    PENICILLUS

    問題数 212025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA IN CLUSTER

    問題数 162025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA BORNE SINGLY

    問題数 122025/10/08

    ZYGOMYCETE/HYALINE SEPTATE GROUP

    問題数 492025/10/08

    YEAST AND YEAST LIKE ORGANISMS

    問題数 722025/10/15

    HEMOCYTOMETRY

    問題数 832025/10/03

    HEMOGLOBIN

    問題数 1002025/10/04

    HEMOGLOBIN PART 2

    問題数 262025/10/05

    OXYGEN DISSOCIATION CURVE

    問題数 282025/10/14

    QUANTIFICATION OF HBF

    問題数 762025/10/12

    YEAST AND YEAST LIKE ORGANISMS

    問題数 702025/10/26