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AUTOIMMUNITY

  • Jef Marc Valencia

    • 問題数 89 • 12/4/2024

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  • 1

    Selective destruction of the insulin producing b cells of the islets of Langerhans in the pancreas

    DM 1

  • 2

    Chronic systemic inflammatory disorder in which joint cartilage ligaments and tendons are destroyed

    RHEUMATOID ARTHRITIS

  • 3

    Immune complexes are formed and these lodge in the basement membrane of kidney skin and joints

    SYSTEMIC LUPUS ERYTHEMATOSUS

  • 4

    Unregulated secretion of T3 and T4 due to stimulation of TSH receptor by antibody

    GRAVES DISEASE

  • 5

    Destruction of the thyroid gland

    HASHIMOTOS THYROIDITIS

  • 6

    Destruction of the parietal cells of the stomach mucosa leading to intrinsic factor defieciency

    PERNICIOUS ANEMIA

  • 7

    Antibodies involved in DM1

    ANTI GLUTAMIC ACID DECARBOXYLASE, ANTI INSULIN ANTIBODY

  • 8

    Antibodies involved in Graves disease

    ANTI TSH RECEPTOR ANTIBODY

  • 9

    Antibodies involved in Hashimotos Thyroiditis

    ANTI THYROID PEROXIDASE ANTIBODY

  • 10

    Antibodies involved in Pernicious Anemia

    ANTI PARIETAL CELL ANTIBODY, ANTI INTRINSIC FACTOR ANTIBODY

  • 11

    Most specific antibody for Systemic Lupus Erythematosus

    ANTI dsDNA

  • 12

    HLA associated to RA

    HLA DR4

  • 13

    HLA associated in SLE

    HLA DR2, HLA DR3

  • 14

    HLA associated in Scleroderma

    HLA DR3 WEAK

  • 15

    HLA associated din Sjogrens Syndrome

    HLA DR3

  • 16

    Ratio F/M of RA

    3:1

  • 17

    Ratio F/M of SLE

    10:1

  • 18

    Ratio F/M of MG

    4:1

  • 19

    Ratio F/M of Scleroderma

    3:1

  • 20

    Ratio F/M of Sjogrens Syndrome

    10:1

  • 21

    The only autoimmune disorder c'mon among men

    ANKYLOSING SPONDYLITIS

  • 22

    Ankylosing Spondylitis primarily affects the

    SACROILIAC JOINT, VERTEBRAL JOINT, LARGE PERIPHERAL JOINT

  • 23

    Causes some of the vertebrae in the spine to fuse inducing stiffness in lower back and hips. May also induced neck pain and fatigue

    ANKYLOSING SPONDYLITIS

  • 24

    Antibody involved in Multiple Sclerosis

    AUTO REACTIVE T CELL

  • 25

    An autoimmune disease that destroys myelin sheath leading to numerous neurological dysfunctions

    MULTIPLE SCLEROSIS

  • 26

    A chronic systemic inflammatory disease primarily involving the joints

    RHEUMATOID ARTHRITIS

  • 27

    An IgG auto ab involves in RA

    RHEUMATOID FACTOR

  • 28

    Rheumatoid factor attaches to what part of antibody causing pain in joints

    FRAGMENT CRYSTALLIZABLE

  • 29

    Refers to advance cases of joint deformities caused by RA

    INVASIVE PANNUS

  • 30

    Invasive pannus consists of the following

    MACROPHAGE, MAST CELL, FIBROBLAST

  • 31

    These substances are present in synovial fluid in RA cases

    ORGANIZED LYMPHOID TISSUE, CD4 T CELL, B CELL, MACROPHAGE

  • 32

    What WBC is increased in synovial fluid due to RA

    NEUTROPHIL

  • 33

    A multi organ autoimmune disease in which patients develop autoantibodies to a number of self antigen

    SYSTEMIC LUPUS ERYTHEMATOSUS

  • 34

    These substances in serum level drops in cases of SLE

    C3, C4

  • 35

    Complement fixing antibodies involved in SLE cases

    IGG, IGM

  • 36

    These are major symptoms of SLE

    AUTOIMMUNE HEMOLYTIC ANEMIA, THROMBOCYTOPENIA, VASCULITIS, GLOMERULONEPHRITIS, ARTHRITIS

  • 37

    These are the reasons that leads to tissue destruction in SLE

    IMMUNE COMPLEX DEPOSITION, SUBSEQUENT COMPLEMENT ACTIVATION

  • 38

    Refers to the butterfly rash in SLE. It is red or purplish and mild scaly

    MALAR RASH

  • 39

    Percentage of occurrence of malar rsh in SLE pxt

    46-65

  • 40

    Refers to the autoimmune responses directed against self antigens present in many organs and tissues of the body resulting in widespread tissue damage to the host.

    ORGAN NON SPECIFIC AUTOIMMUNE DISEASE

  • 41

    Myasthenia Gravis Occurs in

    NEUROMUSCULAR JUNCTION

  • 42

    An autoimmune disease which breakdown normal communication between nerves and muscles causing breakdown and fatigue of any muscle

    MYASTHENIA GRAVIS

  • 43

    Where do auto abs binds in MG

    NICOTINIC RECEPTOR

  • 44

    Ab involves in MG

    ANTIBODY AGAINST NICOTINIC RECEPTOR

  • 45

    This organic compound excites nerve cells which is inhibited in MG

    ACETYLCHOLINE

  • 46

    These autoimmune disorder which autoantibodies bind to TSH receptor on thyroid

    GRAVES DISEASE

  • 47

    Graves disease causes overproduction of thyroid hormone causing

    HYPERTHYROIDISM

  • 48

    Other hyperthyroidism, what are the major s/s of graves disease

    GRAVE OPTHAMOPATHY, GRAVE DERMOPATHY

  • 49

    Responsible for releasing TRH

    HYPOTHALAMUS

  • 50

    This is where the TSH came from

    ANTERIOR PITUITARY GLAND

  • 51

    Hormones that may increase in Graves dx

    TRIIODOTHYRONINE, THYROXINE

  • 52

    A condition caused by autoimmune responses against beta cells resulting to their destruction

    INSULIN DEPENDANT DIABETES

  • 53

    Antibody involved in DM1 which is against the beta cells that migrate to pancreas

    SELF REACTIVE CYTOTOXIC T CELL

  • 54

    Autoantibodies to beta cells may activate__ causing destruction to beta cell

    COMPLEMENT CASCADE

  • 55

    This cells produces insulin

    BETA CELL

  • 56

    3 P's of s/s in DMs

    POLYURIA, POLYDIPSIA, POLYPHAGIA

  • 57

    This refers to the enlarged, inflamed, hypofunctioning thyroid

    HASHIMOTOS THYROIDITIS

  • 58

    This is caused by the autoantibodies to certain antigens on the membrane kidney glomeruli and lung alveoli resulting in an inflammatory reactions in lungs and kidney

    GOODPASTEUR SYNDROME

  • 59

    Refers to bleeding in the lungs due to goodpasteur syndrome

    PULMONARY HEMORRHAGE

  • 60

    Specific AB for Goodpasteur syndrome

    ANTI GLOMERULAR BASEMENT MEMBRANE ANTIBODY

  • 61

    Refers to the condition which autoantibodies to platelets bind to many of the major platelets membrane glycoproteins

    IDIOPATHIC THROMBOCYTOPENIC PURPURA

  • 62

    Major antigens which the platelets autoantibodies bind

    GpIIb/IIIa, GpIb/IX

  • 63

    Classic symptoms of Idiopathic Thrombocytopenic Purpura

    PETECHIAE, BRUISING, BLEEDING

  • 64

    Procedures of Primary Hemostasis

    ADHESION, AGGREGATION, VISCOUS METAMORPHASIS

  • 65

    Components of ADHESION primary hemostasis

    Gp Ib, VON WILLEBRAND FACTOR

  • 66

    Components of aggregation primary hemostasis

    Gp IIb, Gp IIIa

  • 67

    Procedure of Primary Hemostasis which bind to broken blood vessel

    ADHESION

  • 68

    Procedure of Primary Hemostasis which platelets bind together

    AGGREGATION

  • 69

    Procedure of Primary Hemostasis which adapt wound size

    VISCOUS METAMORPHASIS

  • 70

    A Chronic disease resulting form the non absorption of vit b12

    PERNICIOUS ANEMIA

  • 71

    What is being detected in PA diagnostic

    IF BLOCKING ANTIBODY

  • 72

    Carrier protein of Vit B12 which is inhibited in PA cases

    INTRINSIC FACTOR

  • 73

    What is the basic abnormality of the PA disease

    SEVERE ATROPHIC GASTRITIS

  • 74

    Characteristics of RBC in PA

    MEGALOBLASTIC

  • 75

    A condition which the autoantibodies bind to antigen on RBCS and lead to the lysis of RBCS

    AUTOIMMUNE HEMOLYTIC ANEMIA

  • 76

    Cephalosporins and Dapsone acts as__ in AIHA

    HAPTEN

  • 77

    Induces immune system to produce antibodies in AIHA

    DRUG RBC ANTIGEN COMPLEX

  • 78

    An AIHA caused by IGG autoantibodies

    WARM AUTOIMMUNE HEMOLYTIC ANEMIA

  • 79

    AIHA caused by IGM

    COLD AUTOIMMUNE HEMOLYTIC ANEMIA

  • 80

    An AIHA which IGG protein reacts with RBC in colder parts of the body producing complement component binding

    PAROXYSMAL COLD HEMOGLOBINURIA

  • 81

    Paroxysmal Cold HEMOGLOBINURIA specific abs

    BIPHASIC HEMOLYSIN

  • 82

    Biphasic Hemolysin ___to RBC when cold

    BIND

  • 83

    Biphasic Hemolysin ___to RBC when WARM

    LYSE

  • 84

    PCH sample must be put in

    WARM TEMPERATURE

  • 85

    Organ located in a privilege site

    CORNEA

  • 86

    Bacterial species which causes auto anti I cold agglutinins

    MYCOPLASMA PNEUMONIAE

  • 87

    Problem of self/non self discrimination

    AUTOIMMUNITY

  • 88

    Who described autoimmunituy phenomenon as horror autotoxicus

    PAUL EHRLICH

  • 89

    Ehrlich described autoimmunity as__ meaning fear of self poisoning

    HORROR AUTOTOXICUS

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    Signs and Symptoms and Tables of Renal Disorder

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    CHROMOSOME SHITS

    問題数 242025/04/02

    METABOLIC DISORDER-MCQ

    問題数 742025/04/03

    TABULATED METABOLIC DISORDER

    問題数 192025/04/03

    FECAL ANALYSIS-MCQ

    問題数 862025/04/03

    BRISTOL STOOL CHART

    問題数 72025/04/03

    FECALYSIS CHEMICAL EXAMINATION

    問題数 512025/04/03

    BIOLOGICAL PREGNANCY TEST

    問題数 62025/03/31

    SPERM

    問題数 632025/04/22

    SPERM 2

    問題数 692025/04/22

    Fructose test table

    問題数 52025/04/22

    Sperm motility table

    問題数 82025/04/22

    PROTOZOAN

    問題数 812025/04/24

    CSF

    問題数 962025/04/29

    AMOEBA

    問題数 222025/04/29

    MCQ-CHEMICAL EXAMINATION OF URINE PART 2

    問題数 792025/05/03

    PERICARDIAL FLUID

    問題数 662025/05/04

    MCQ-SPERM

    問題数 592025/05/03

    MCQ-SPERM 2

    問題数 882025/05/03

    MCQ-AMNIOTIC FLUID

    問題数 732025/05/08

    HEMOFLAGELLATES

    問題数 682025/05/04

    Sex disorder

    問題数 602025/05/05

    NEMATODES

    問題数 62025/05/06

    MCQ-PERICARDIAL FLUID

    問題数 592025/05/11

    PHASMID NEMATODES

    問題数 52025/05/06

    HOOKWORMS

    問題数 92025/05/06

    MCQ-CSF

    問題数 942025/05/03

    BLOOD AND TISSUE NEMATODE

    問題数 82025/05/06

    PLATYHELMINTHS

    問題数 132025/05/06

    MCQ-CSF2

    問題数 242025/05/03

    TREMATODES

    問題数 72025/05/06

    INTRODUCTION

    問題数 362025/06/10

    INTRODUCTION TABLE

    問題数 412025/06/10

    CLASSFICATION OF ENZYME

    問題数 472025/06/11

    ENZYME VARIANTS

    問題数 412025/06/11

    FACTORS AFFECTING ENZYME ACTIVITY

    問題数 902025/06/12

    INTRODUCTION TO ENZYMOLOGY-MCQ

    問題数 412025/06/26

    CLASS AND VARIANT OF ENZYME-MCQ

    問題数 772025/06/26

    PITUITARY GLAND PART 2

    問題数 52025/07/04

    THYROID GLAND

    問題数 712025/07/04

    PARATHYROID GLAND

    問題数 122025/07/04

    ADRENAL GLAND

    問題数 772025/07/04

    SEX GLANDS

    問題数 352025/07/04

    OTHER GLANDS

    問題数 82025/07/04

    ACID BASE BALANCE

    問題数 512025/07/10

    TRACE ELEMENT

    問題数 792025/07/10

    VITAMINS

    問題数 272025/07/10

    TUMOR MARKERS

    問題数 252025/07/10

    TOXICOLOGY

    問題数 722025/07/13

    DRUG OF ABUSE

    問題数 952025/07/13

    TOXINS

    問題数 572025/07/13

    TDM

    問題数 942025/07/13

    ENDOCRINOLOGY

    問題数 962025/07/16

    ENDROCRINOLOGY PART 2

    問題数 462025/07/16

    FACTORS AFFECTING ENZYME ACTIVITY-MCQ

    問題数 892025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ

    問題数 992025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ2

    問題数 872025/07/18

    MEDICAL TERMINOLOGIES

    問題数 362025/08/17

    INTRODUCTION TO HEMA 1

    問題数 292025/08/17

    LABORATORY SAFETY

    問題数 232025/08/18

    TERMINOLOGIES

    問題数 512025/08/21

    LABORATORY 1

    問題数 182025/08/22

    LABORATORY 3

    問題数 532025/08/22

    HEMATOPOIESIS

    問題数 622025/08/23

    THEORIES ON BLOOD FORMATION

    問題数 552025/08/30

    ERYTHROPOIESIS

    問題数 462025/08/30

    LEUKOPOIESIS

    問題数 1002025/08/30

    LEUKOPOIESIS II AND MONOPOIESIS

    問題数 422025/09/01

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/24

    MYCOLOGY PROPER

    問題数 712025/09/01

    FUNGAL PATHOGENESIS

    問題数 352025/09/01

    CLASSIFICATION OF FUNGI

    問題数 452025/09/06

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS

    問題数 742025/09/06

    MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 542025/09/06

    Mind mapping

    問題数 92025/09/07

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/13

    MYCOLOGY PROPER MCQ

    問題数 592025/09/13

    FUNGAL PATHOGENESIS MCQ

    問題数 372025/09/13

    CLASSIFICATION OF FUNGI MCQ

    問題数 332025/09/13

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS MCQ

    問題数 742025/09/13

    MCQ-MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 532025/09/14

    THE SUPEFICIAL FUNGI

    問題数 342025/09/12

    THE CUTANEOUS FUNGI

    問題数 582025/09/13

    SUBCUTANEOUS FUNGI

    問題数 552025/09/13

    SYSTEMIC FUNGI

    問題数 282025/09/13

    LYMPHOPOIESIS

    問題数 442025/09/07

    MEGAKARYOPOIESIS

    問題数 342025/09/07

    INTRODUCTION TO HEMA1 MCQ

    問題数 452025/09/10

    HEMATOPOIESIS

    問題数 582025/09/14

    THEORIES ON BLOOD FORMATION

    問題数 462025/09/14

    ERYTHROPOIESIS MCQ

    問題数 412025/09/14

    LEUKOPOIESIS MCQ

    問題数 942025/09/10

    LEUKOPOIESIS II AND MONOPOIESIS MCQ

    問題数 392025/09/14

    LYMPHOPOIESIS MCQ

    問題数 392025/09/10

    MEGAKARYOPOIESIS MCQ

    問題数 392025/09/10

    BLOOD COLLECTION

    問題数 352025/09/10

    LABORATORY SAFETY

    問題数 212025/09/17

    LABORATORY 1

    問題数 162025/09/17

    LABORATORY 3

    問題数 472025/09/17

    BLOOD COLLECTION MCQ

    問題数 792025/09/17

    DEMATIACEOUS OPPORTUNISTIC FUNGI

    問題数 522025/09/30

    PENICILLUS

    問題数 212025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA IN CLUSTER

    問題数 162025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA BORNE SINGLY

    問題数 122025/10/08

    ZYGOMYCETE/HYALINE SEPTATE GROUP

    問題数 492025/10/08

    YEAST AND YEAST LIKE ORGANISMS

    問題数 722025/10/15

    HEMOCYTOMETRY

    問題数 832025/10/03

    HEMOGLOBIN

    問題数 1002025/10/04

    HEMOGLOBIN PART 2

    問題数 262025/10/05

    OXYGEN DISSOCIATION CURVE

    問題数 282025/10/14

    QUANTIFICATION OF HBF

    問題数 762025/10/12

    YEAST AND YEAST LIKE ORGANISMS

    問題数 702025/10/26