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AUTOIMMUNITY
  • Jef Marc Valencia

  • 問題数 89 • 12/4/2024

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    問題一覧

  • 1

    Components of ADHESION primary hemostasis

    Gp Ib, VON WILLEBRAND FACTOR

  • 2

    Antibody involved in DM1 which is against the beta cells that migrate to pancreas

    SELF REACTIVE CYTOTOXIC T CELL

  • 3

    Classic symptoms of Idiopathic Thrombocytopenic Purpura

    PETECHIAE, BRUISING, BLEEDING

  • 4

    Ratio F/M of Sjogrens Syndrome

    10:1

  • 5

    What is the basic abnormality of the PA disease

    SEVERE ATROPHIC GASTRITIS

  • 6

    3 P's of s/s in DMs

    POLYURIA, POLYDIPSIA, POLYPHAGIA

  • 7

    AIHA caused by IGM

    COLD AUTOIMMUNE HEMOLYTIC ANEMIA

  • 8

    Where do auto abs binds in MG

    NICOTINIC RECEPTOR

  • 9

    Refers to the butterfly rash in SLE. It is red or purplish and mild scaly

    MALAR RASH

  • 10

    Chronic systemic inflammatory disorder in which joint cartilage ligaments and tendons are destroyed

    RHEUMATOID ARTHRITIS

  • 11

    Characteristics of RBC in PA

    MEGALOBLASTIC

  • 12

    Organ located in a privilege site

    CORNEA

  • 13

    Antibodies involved in Pernicious Anemia

    ANTI PARIETAL CELL ANTIBODY, ANTI INTRINSIC FACTOR ANTIBODY

  • 14

    Procedures of Primary Hemostasis

    ADHESION, AGGREGATION, VISCOUS METAMORPHASIS

  • 15

    Invasive pannus consists of the following

    MACROPHAGE, MAST CELL, FIBROBLAST

  • 16

    An autoimmune disease which breakdown normal communication between nerves and muscles causing breakdown and fatigue of any muscle

    MYASTHENIA GRAVIS

  • 17

    Components of aggregation primary hemostasis

    Gp IIb, Gp IIIa

  • 18

    Major antigens which the platelets autoantibodies bind

    GpIIb/IIIa, GpIb/IX

  • 19

    Biphasic Hemolysin ___to RBC when cold

    BIND

  • 20

    Specific AB for Goodpasteur syndrome

    ANTI GLOMERULAR BASEMENT MEMBRANE ANTIBODY

  • 21

    These are the reasons that leads to tissue destruction in SLE

    IMMUNE COMPLEX DEPOSITION, SUBSEQUENT COMPLEMENT ACTIVATION

  • 22

    An AIHA caused by IGG autoantibodies

    WARM AUTOIMMUNE HEMOLYTIC ANEMIA

  • 23

    An autoimmune disease that destroys myelin sheath leading to numerous neurological dysfunctions

    MULTIPLE SCLEROSIS

  • 24

    Problem of self/non self discrimination

    AUTOIMMUNITY

  • 25

    Refers to the autoimmune responses directed against self antigens present in many organs and tissues of the body resulting in widespread tissue damage to the host.

    ORGAN NON SPECIFIC AUTOIMMUNE DISEASE

  • 26

    Unregulated secretion of T3 and T4 due to stimulation of TSH receptor by antibody

    GRAVES DISEASE

  • 27

    A condition caused by autoimmune responses against beta cells resulting to their destruction

    INSULIN DEPENDANT DIABETES

  • 28

    These are major symptoms of SLE

    AUTOIMMUNE HEMOLYTIC ANEMIA, THROMBOCYTOPENIA, VASCULITIS, GLOMERULONEPHRITIS, ARTHRITIS

  • 29

    Antibody involved in Multiple Sclerosis

    AUTO REACTIVE T CELL

  • 30

    This is caused by the autoantibodies to certain antigens on the membrane kidney glomeruli and lung alveoli resulting in an inflammatory reactions in lungs and kidney

    GOODPASTEUR SYNDROME

  • 31

    A chronic systemic inflammatory disease primarily involving the joints

    RHEUMATOID ARTHRITIS

  • 32

    Antibodies involved in DM1

    ANTI GLUTAMIC ACID DECARBOXYLASE, ANTI INSULIN ANTIBODY

  • 33

    This cells produces insulin

    BETA CELL

  • 34

    Responsible for releasing TRH

    HYPOTHALAMUS

  • 35

    Who described autoimmunituy phenomenon as horror autotoxicus

    PAUL EHRLICH

  • 36

    Procedure of Primary Hemostasis which bind to broken blood vessel

    ADHESION

  • 37

    What is being detected in PA diagnostic

    IF BLOCKING ANTIBODY

  • 38

    This organic compound excites nerve cells which is inhibited in MG

    ACETYLCHOLINE

  • 39

    Refers to the condition which autoantibodies to platelets bind to many of the major platelets membrane glycoproteins

    IDIOPATHIC THROMBOCYTOPENIC PURPURA

  • 40

    Myasthenia Gravis Occurs in

    NEUROMUSCULAR JUNCTION

  • 41

    Destruction of the thyroid gland

    HASHIMOTOS THYROIDITIS

  • 42

    Ab involves in MG

    ANTIBODY AGAINST NICOTINIC RECEPTOR

  • 43

    The only autoimmune disorder c'mon among men

    ANKYLOSING SPONDYLITIS

  • 44

    This is where the TSH came from

    ANTERIOR PITUITARY GLAND

  • 45

    Complement fixing antibodies involved in SLE cases

    IGG, IGM

  • 46

    Induces immune system to produce antibodies in AIHA

    DRUG RBC ANTIGEN COMPLEX

  • 47

    Ratio F/M of RA

    3:1

  • 48

    Biphasic Hemolysin ___to RBC when WARM

    LYSE

  • 49

    HLA associated to RA

    HLA DR4

  • 50

    HLA associated in SLE

    HLA DR2, HLA DR3

  • 51

    Hormones that may increase in Graves dx

    TRIIODOTHYRONINE, THYROXINE

  • 52

    Ratio F/M of MG

    4:1

  • 53

    PCH sample must be put in

    WARM TEMPERATURE

  • 54

    Ratio F/M of SLE

    10:1

  • 55

    An IgG auto ab involves in RA

    RHEUMATOID FACTOR

  • 56

    Refers to bleeding in the lungs due to goodpasteur syndrome

    PULMONARY HEMORRHAGE

  • 57

    Ehrlich described autoimmunity as__ meaning fear of self poisoning

    HORROR AUTOTOXICUS

  • 58

    Procedure of Primary Hemostasis which platelets bind together

    AGGREGATION

  • 59

    Bacterial species which causes auto anti I cold agglutinins

    MYCOPLASMA PNEUMONIAE

  • 60

    An AIHA which IGG protein reacts with RBC in colder parts of the body producing complement component binding

    PAROXYSMAL COLD HEMOGLOBINURIA

  • 61

    Ankylosing Spondylitis primarily affects the

    SACROILIAC JOINT, VERTEBRAL JOINT, LARGE PERIPHERAL JOINT

  • 62

    Immune complexes are formed and these lodge in the basement membrane of kidney skin and joints

    SYSTEMIC LUPUS ERYTHEMATOSUS

  • 63

    A condition which the autoantibodies bind to antigen on RBCS and lead to the lysis of RBCS

    AUTOIMMUNE HEMOLYTIC ANEMIA

  • 64

    Graves disease causes overproduction of thyroid hormone causing

    HYPERTHYROIDISM

  • 65

    Paroxysmal Cold HEMOGLOBINURIA specific abs

    BIPHASIC HEMOLYSIN

  • 66

    Rheumatoid factor attaches to what part of antibody causing pain in joints

    FRAGMENT CRYSTALLIZABLE

  • 67

    Antibodies involved in Graves disease

    ANTI TSH RECEPTOR ANTIBODY

  • 68

    HLA associated in Scleroderma

    HLA DR3 WEAK

  • 69

    Antibodies involved in Hashimotos Thyroiditis

    ANTI THYROID PEROXIDASE ANTIBODY

  • 70

    Carrier protein of Vit B12 which is inhibited in PA cases

    INTRINSIC FACTOR

  • 71

    A multi organ autoimmune disease in which patients develop autoantibodies to a number of self antigen

    SYSTEMIC LUPUS ERYTHEMATOSUS

  • 72

    These autoimmune disorder which autoantibodies bind to TSH receptor on thyroid

    GRAVES DISEASE

  • 73

    Ratio F/M of Scleroderma

    3:1

  • 74

    Autoantibodies to beta cells may activate__ causing destruction to beta cell

    COMPLEMENT CASCADE

  • 75

    Other hyperthyroidism, what are the major s/s of graves disease

    GRAVE OPTHAMOPATHY, GRAVE DERMOPATHY

  • 76

    Most specific antibody for Systemic Lupus Erythematosus

    ANTI dsDNA

  • 77

    Destruction of the parietal cells of the stomach mucosa leading to intrinsic factor defieciency

    PERNICIOUS ANEMIA

  • 78

    What WBC is increased in synovial fluid due to RA

    NEUTROPHIL

  • 79

    This refers to the enlarged, inflamed, hypofunctioning thyroid

    HASHIMOTOS THYROIDITIS

  • 80

    A Chronic disease resulting form the non absorption of vit b12

    PERNICIOUS ANEMIA

  • 81

    Selective destruction of the insulin producing b cells of the islets of Langerhans in the pancreas

    DM 1

  • 82

    Procedure of Primary Hemostasis which adapt wound size

    VISCOUS METAMORPHASIS

  • 83

    Cephalosporins and Dapsone acts as__ in AIHA

    HAPTEN

  • 84

    HLA associated din Sjogrens Syndrome

    HLA DR3

  • 85

    Causes some of the vertebrae in the spine to fuse inducing stiffness in lower back and hips. May also induced neck pain and fatigue

    ANKYLOSING SPONDYLITIS

  • 86

    Refers to advance cases of joint deformities caused by RA

    INVASIVE PANNUS

  • 87

    These substances are present in synovial fluid in RA cases

    ORGANIZED LYMPHOID TISSUE, CD4 T CELL, B CELL, MACROPHAGE

  • 88

    Percentage of occurrence of malar rsh in SLE pxt

    46-65

  • 89

    These substances in serum level drops in cases of SLE

    C3, C4