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TUMOR MARKERS

  • Jef Marc Valencia

    • 問題数 25 • 7/10/2025

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  • 1

    Produced directly by the tumor or as an effect of the tumor on healthy tissue

    TUMOR MARKER

  • 2

    Characteristics of an ideal tumor marker

    SPECIFICITY, SENSITIVITY, HALF LIFE, CONSISTENT CONCENTRATION

  • 3

    Found in very small amounts in the blood of healthy individuals which increased in some people with CA or non-cancerous conditions

    CARCINOEMBRYONIC ANTIGEN

  • 4

    Produced by both normal & abnormal prostate cells which elevates in men who have a benign growth (very common in older men) or malignant growth in the prostate; indicative for the need for other tests to determine whether CA is present

    PROSTATE SPECIFIC ANTIGEN

  • 5

    Initially found in the prostate but was later found to be present in a variety of tissue and increased levels in blood in patients with Prostate CA (advanced disease)

    PROSTATIC ACID PHOSPHATASE

  • 6

    PAP is c'monly seen in conditions like

    MULTIPLE MYELOMA, OSTEOGENIC SARCOMA

  • 7

    Protein produced by a variety of cells particularly by ovarian cancer cells which elevated in patients’ w/ breast & colorectal cancers, Pregnant women, endometriosis, ovarian cysts or fibroids and Cirrhosis, hepatitis or pancreatitis

    CA 125

  • 8

    Produced by the developing fetus; AFP falls to a low level after birth

    ALPHA FETOPROTEIN

  • 9

    Normally secreted by the placenta during pregnancy

    HUMAN CHORIONIC GONADOTROPIN

  • 10

    HCG may increased in ___CA that develops from an abnormal fertilized egg

    TROPHOBLASTIC DISEASE

  • 11

    Found throughout the body which nearly every type of CA & other diseases can cause its levels to increased

    LACTATE DEHYDROGENASE

  • 12

    Detected in patient’s w/ neuroblastoma, small cell lung CA, medullary thyroid CA, carcinoid tumors, pancreatic endocrine tumors& melanoma

    NEURON SPECIFIC ENOLASE

  • 13

    Hepatic and testicular cancers

    AFP

  • 14

    Pancreatic cancer

    AMYLASE

  • 15

    Breast or ovarian cancer

    BRCA 1

  • 16

    Ovarian cancer (treatment and recurrence)

    CA 125

  • 17

    Brease cancer (treatment and recurrence)

    CA 15.3, CA 27.29

  • 18

    Gastric, pancreatic and colorectal cancers

    CA 19.9

  • 19

    Gastric and pancreatic cancers (treatment and recurrence)

    CA 50

  • 20

    Medullary thyroid cancer

    CALCITONIN

  • 21

    Colorectal, stomach, breast, lung cancer (treatment and recurrence)

    CEA

  • 22

    Small cell lung cancer, prostate cancer

    CK-1

  • 23

    Breast cancer

    ESTROGEN RECEPTOR, HER2/NEU, CATHEPSIN D

  • 24

    Hepatoma

    GGT

  • 25

    Urinary bladder cancer

    NUCLEAR MATRIX PROTEIN

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